One common medication prescribed by doctors is trimethoprim-sulfamethoxazole (sometimes called co-trimoxazole or TMP/SMX), the generic form of Bactrim . (khealth.com)
As with any medication, trimethoprim-sulfamethoxazole is not for everyone. (khealth.com)
To help you be an informed patient-and to make prescription medicine more transparent-this article will address what trimethoprim-sulfamethoxazole is, what it's used for, potential side effects, and how to take it. (khealth.com)
What Is Trimethoprim-sulfamethoxazole? (khealth.com)
Trimethoprim-sulfamethoxazole, or generic Bactrim, is an FDA-approved prescription antibiotic medication. (khealth.com)
Trimethoprim-sulfamethoxazole works by decreasing the bacteria infecting a person's body. (khealth.com)
Trimethoprim-sulfamethoxazole is an antibacterial drug used to treat infectious diseases in the body caused by bacteria. (khealth.com)
Antibiotics, including trimethoprim-sulfamethoxazole, don't work for viral infections such as the common cold and influenza. (khealth.com)
Can You Get Trimethoprim-sulfamethoxazole Online? (khealth.com)
Since trimethoprim-sulfamethoxazole is a prescription antibiotic medication, you need a healthcare provider's prescription to get it. (khealth.com)
What Forms Does Trimethoprim-sulfamethoxazole Come In? (khealth.com)
Trimethoprim-sulfamethoxazole comes in two forms: liquid and tablet. (khealth.com)
What Are Common Dosages of Trimethoprim-sulfamethoxazole? (khealth.com)
Your doctor will work with you to determine the appropriate dosage of trimethoprim-sulfamethoxazole based on your infection, its severity, and your general health. (khealth.com)
Antibiotics less likely to reduce OCP effectiveness include ciprofloxacin 4 and trimethoprim/sulfamethoxazole. (aafp.org)
For some antibiotics, such as trimethoprim-sulfamethoxazole, metronidazole and tinidazole, drinking alcohol while taking the antibiotic can cause nausea, vomiting, headache, rapid heart beat and flushing. (livestrong.com)
Increased risk of hemolysis in G6PD-deficient patients with concomitant trimethoprim/sulfamethoxazole, other folic acid antagonists (eg, pyrimethamine), anticonvulsants, rifampin, St. John's wort. (renalandurologynews.com)
NBDPS data has shown that periconceptional (i.e., one month before conception through the third month of pregnancy) use of trimethoprim-sulfamethoxazole (e.g. (cdc.gov)
c Trimethoprim 3.5-4 mg/kg/dose every 8-12 hours is suggested (adult doses are higher than typical trimethoprim-sulfamethoxazole doses of 1 double-strength orally twice daily). (medscape.com)
Antibiotics5
In addition, a discussion of possible interactions of OCPs with antibiotics would be very helpful. (aafp.org)
Another systematic review concluded that current evidence does not support the existence of drug interactions between OCPs and nonrifamycin antibiotics. (aafp.org)
Sulfamethoxazole-trimethoprim: A potential drug interaction exists with concomitant use of sulfamethoxazole-trimethoprim and folinic acid. (wikipedia.org)
Warfarin3
Finally, warfarin is very sensitive to drug-drug interactions involving its metabolism or function and great care must be given to starting or stopping concurrent medications in patients on warfarin therapy. (nih.gov)
Overdose of the oral anticoagulant warfarin (Coumadin), or drug interactions with warfarin, can lead to toxicity. (medscape.com)
Lack of familiarity with the interactions between warfarin and other drugs may lead to clinically relevant and avoidable increases or decreases in prothrombin time (PT). (medscape.com)
Pneumocystis1
Folinic acid has been shown to decrease the efficacy of sulfamethoxazole-trimethoprim in the treatment of Pneumocystis jirovecii (formerly known as Pneumocystis carinii), a common cause of pneumonia in AIDS patients. (wikipedia.org)
Warnings1
Please see Adult OI guidelines for information about drug interactions, including warnings about interactions between boceprevir and HIV protease inhibitors. (hiv.gov)
There is the potential for significant drug interactions and overlapping toxicities in patients receiving medications for treatment or prevention of opportunistic infections (OIs). (hiv.gov)
To get a better understanding of a possible mechanism for the teratogenicity of these and other medications, such as gene-medication interaction, the Birth Defects Monitoring and Research Branch is planning a genome-wide association study (GWAS) with enhanced pharmacogenomic content among mothers of infants with and without birth defects who used specific medications. (cdc.gov)
Antibiotic1
Antimicrobial activity of ciprofloxacin against Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus determined by the killing curve method: antibiotic comparisons and synergistic interactions. (microbiologyresearch.org)
Drug13
Still, a drug interaction that could increase the risk of an unintended pregnancy is certainly clinically relevant. (aafp.org)
Regarding interactions with OCPs and antiepileptics, a recent study showed the drug interactions between ethinyl estradiol/estradiol and valproate (Depacon), oxcarbazepine (Trileptal), and carbamazepine to be among the most prevalent interactions in a group of 395 women with epilepsy seen in a tertiary outpatient clinic. (aafp.org)
A systematic review concluded that pharmacokinetic and ovulation outcomes support a clinically relevant drug interaction between OCPs and rifampin and, to a lesser extent, rifabutin, but data are limited for other rifamycins. (aafp.org)
This is not a complete list of mercaptopurine drug interactions. (rxwiki.com)
In particular, protease inhibitors and non-nucleoside reverse transcriptase inhibitors affect the CYP450 or other transporter systems and may be associated with clinically significant drug interactions. (hiv.gov)
The integrase inhibitor raltegravir is metabolized by UGT1A1 and may be a suitable option when trying to minimize interactions with other drug classes. (hiv.gov)
Table 5 provides clinicians with information regarding known or suspected drug interactions between drugs commonly used for treatment or prevention of HIV-associated OIs and treatment of HIV infection. (hiv.gov)
Drug interaction information is generally obtained from studies involving healthy adult volunteers. (hiv.gov)
When possible, alternative agents with less drug interaction potential or use of therapeutic drug monitoring should be considered. (hiv.gov)
The drug interactions included in this table were selected on the basis of their potential clinical significance and are not inclusive of all potential drug interactions (see drug label and the drug interaction websites listed for complete information on drug interactions). (hiv.gov)
Due to system maintenance, the drug interactions feature you are attempting to access is temporarily unavailable. (medscape.com)
Drug interactions are extensive and many known examples are enumerated below. (medscape.com)
Drug interactions may occur with selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, amphetamines, and foods high in tyramine. (medscape.com)
Diarrhea1
Sulfamethoxazole trimethoprim dose may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. (canadadrugs.co)
Dose5
3 Ketoconazole's interaction is less well documented, but combining that agent with low-estrogen (low-dose) OCPs warrants caution. (aafp.org)
Sulfamethoxazole trimethoprim dose should not be used in children less than 2 months of age due to the risk of serious side effects. (canadadrugs.co)
The objective of the present study was to evaluate reports of suspected liver reactions to drugs used for treating COVID-19, compare their use for other indications among patients with COVID-19, and assess possible interactions between them. (bvsalud.org)
Clindamycin1
However, there is no documented interaction between clindamycin and alcohol, so you can safely drink wine while taking clindamycin. (livestrong.com)
Bacterial infections2
Trimethoprim with sulfamethoxazole works by destroying bacteria in the body, which can alleviate bacterial infections. (khealth.com)
Sulfamethoxazole is used for treating a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). (canadadrugs.co)
Infections1
Sulfamethoxazole is used for treating only certain types of infections. (canadadrugs.co)
Doses1
2 months: 8mg/kg per day trimethoprim (40mg/kg per day of sulfamethoxazole) in 2 divided doses at 12-hour intervals for 5 days (shigellosis) or 10 days (otitis media, UTIs). (empr.com)
Defining interactions among pharmacogenomic variants and medication use during pregnancy will help inform risk of birth defects. (cdc.gov)
Medicines4
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. (drugs.com)
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. (drugs.com)
Using alcohol or tobacco with certain medicines may also cause interactions to occur. (drugs.com)
Occasionally, Septran DS may have interactions with other medicines. (goodrxmedicine.com)
Potential4
This is a useful article, but I find it curious that it does not mention potential interactions with oral contraceptive pills (OCPs). (aafp.org)
The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. (drugs.com)
Interventions may focus on prescribing safer alternatives when a potential for interaction exists. (harvard.edu)
It is difficult to predict the interaction potential when three or more drugs with similar metabolic pathways are co-administered and there is substantial inter-patient variability in the magnitude of these interactions. (hiv.gov)
Alcohol1
Not much information is available on interactions of this medicine when taken with alcohol. (pharmeasy.in)
Patients1
Il est nécessaire de veiller à l'adéquation des prescriptions de médicaments et d'effectuer un suivi plus vigilant des patients dans le cadre clinique et en laboratoire. (who.int)