• The oral cavity of a new-born baby does not contain bacteria but rapidly becomes colonized with bacteria such as Streptococcus salivarius. (wikipedia.org)
  • Streptococcus mutans was previously considered a primary cause, but recent research promotes the ecologic hypothesis, in which a dysbiosis in the oral microbial community leads to caries. (researchsquare.com)
  • Biofilms are pathogens (10). (cdc.gov)
  • Besides maintaining human health, different sources reported that riboflavin can inhibit or inactivate the growth of different pathogens including bacteria, viruses, fungi and parasites, highlighting the possible role of riboflavin as an antimicrobial agent. (bioseek.eu)
  • Hence, this review aimed to provide some insights on the promising role of riboflavin as an antimicrobial candidate and also a host immune-modulator from a multi-perspective view as well as to discuss the application and challenges on using riboflavin in photodynamic therapy against various pathogens and microbial biofilm-associated infections. (bioseek.eu)
  • Research has shown a direct correlation between the amount of coating on a person's tongue and the total number of anaerobic bacteria present in the coating. (medscape.com)
  • Cover gram-positive and gram-negative organisms and aerobic and anaerobic bacteria, including beta-lactamase-producing organisms. (medscape.com)
  • Oral microbiology is the study of the microorganisms (microbiota) of the oral cavity and their interactions between oral microorganisms or with the host. (wikipedia.org)
  • Factors of note that have been found to affect the microbial colonization of the oral cavity include the pH, oxygen concentration and its availability at specific oral surfaces, mechanical forces acting upon oral surfaces, salivary and fluid flow through the oral cavity, and age. (wikipedia.org)
  • As a diverse environment, a variety of organisms are able to inhabit unique ecological niches present in the oral cavity including the teeth, gingiva, tongue, cheeks, and palates. (wikipedia.org)
  • The development of antibiotic resistance in periodontopathogens is a major issue given that these bacteria may migrate from the oral cavity to other organs where they may cause infections or transfer their antibiotic resistances to other bacterial species. (nature.com)
  • Adverse microbial changes, both in composition and function, can act at several levels within the gut (stool and mucosal) and have also been described in the blood and oral cavity. (jci.org)
  • While dysbiosis in the oral cavity could be a source of systemic inflammation, current cirrhosis treatment modalities are targeted toward the gut-liver axis and do not address the oral microbiome. (jci.org)
  • The human oral cavity is a highly complex ecosystem in which the tooth- and soft-tissue surfaces offer distinct ecological niches for microbial colonization. (biomedcentral.com)
  • Definition Dental Plaque "is a specific but highly variable structural entity, resulting from sequential colonization of microorganisms on tooth surfaces, restorations & other parts of oral cavity, composed of salivary components like mucin, desquamated epithelial cells, debris & microorganisms, all embedded in extracellular gelatinous matrix. (medicpresents.com)
  • Endocarditis can be treated with antibiotic therapy and may cause death.Although S. gordonii initiates dental plaque and the colonization of other pathogenic bacteria on tooth surfaces, S. gordonii is not directly pathogenic in the oral cavity. (datapunk.net)
  • Acid producing normal flora of the oral cavity such as Lactobacillus acidophilus thrive and may become cariogenic in the presence of high sugar intake and fermentable carbohydrates on the enamel, as from carbonated drinks. (fluoridationaustralia.com)
  • Conversely, mastication increases saliva flow, with concomitant cleansing of the oral cavity and reduction in malodor. (medscape.com)
  • The inhibition of quorum sensing, called quorum quenching, may disrupt oral biofilm formation, which is the main etiological factor of oral diseases, including periodontitis. (mdpi.com)
  • In periodontitis, however, the development of periodontal pockets as a result of breakdown of the bone and soft-tissues supporting the teeth, creates a new subgingival niche that promotes growth of bacterial species suited to the environment. (biomedcentral.com)
  • Tannerella forsythia is an anaerobic, fusiform Gram-negative oral pathogen strongly associated with periodontitis, a multibacterial inflammatory disease that leads to the destruction of the teeth-supporting tissue, ultimately causing tooth loss. (karger.com)
  • Periodontitis is a highly prevalent, chronic multifactorial infectious disease, induced by the dysbiotic biofilm that triggers a persistent systemic inflammation and recurrent bacteremia. (intechopen.com)
  • This chapter emphasis the relationship between periodontitis and adverse pregnancy outcomes and the underlying mechanisms that link peridontitis to oral carcinogenesis. (intechopen.com)
  • The oral microbiome, mainly comprising bacteria which have developed resistance to the human immune system, has been known to impact the host for its own benefit, as seen with dental cavities. (wikipedia.org)
  • Researching this discrepancy further by analyzing gut microbes on the strain level could contribute to answering some of the questions relating to contradictions relating to composition and abundance of species in the gut microbiome that are often found. (biotax.co)
  • The aim of this review article is to highlight the role of gut microbiome and inflammation in the pathophysiology of cirrhosis and to introduce the oral-gut-liver axis as a new perspective to consider in future research. (jci.org)
  • Marine Animal Microbiomes: Toward Understanding Host-Microbiome Interactions in a Changing Ocean. (pressbooks.pub)
  • Identified as a constituent of the oral microbiome by Human Oral Microbiome Database. (datapunk.net)
  • This is a relevant aspect to take into consideration because microbial adherence to the dentin is the first step in colonization, including tubule invasion, and the origin of biofilm infections. (opendentistryjournal.com)
  • As a result of recent advances in culture-independent measurements of microbial communities, we know that the human gut is host to roughly a thousand different bacterial species [ 2 ]. (biomedcentral.com)
  • Dysbiotic subgingival communities are characterized by a relative increase in abundance of anaerobic, Gram-negative bacterial species that can exploit protein-rich GCF as a nutrient source, promoting development of a proteolytic community phenotype. (biomedcentral.com)
  • The mouth is home to hundreds of bacterial species with various nutritional preferences. (medscape.com)
  • Our results show increased microbial diversity in the tumor microenvironment, with changes in the abundances of commensal and pathogenic bacterial taxa, including Fusobacterium and Providencia . (biomedcentral.com)
  • Several studies have illustrated the therapeutic efficacy of photoactivated riboflavin against nosocomial infections and multidrug resistant bacterial infections as well as microbial associated biofilm infections, revealing the potential role of riboflavin as a promising antimicrobial candidate, which could serve as one of the alternatives in fighting the global crisis of the emergence of antimicrobial resistance seen in different pathogenic microbes. (bioseek.eu)
  • Organisms within the genus comprise both pathogenic bacteria, such as S.pneumoniae and S. pyogenes, and non-pathogenic species that inhabit the mouth, skin, intestine and upper respiratory tract of humans including S. gordonii and S. mutans. (datapunk.net)
  • Of particular interest is the role of oral microorganisms in the two major dental diseases: dental caries and periodontal disease. (wikipedia.org)
  • Candida show uniform resistance to a wide spectrum of the The devices become colonized by the microorganisms that currently available conventional antifungal agents, which form a biofilm of cells, the detachment of which can result implies that antimicrobial drugs that specifically target in septicemia (2-5,8,9,14,15). (cdc.gov)
  • The need for retreatment may be attributed to either reinfection by oral bacteria or, more often, to the persistence and regrowth of microorganisms that were not eliminated during the previous treatment. (opendentistryjournal.com)
  • Effects of fermented soymilk with Lactobacillus Lactobacillus son bacterias anaerobias facultativas y acidificantes que colonizan principalmente el estómago y el intestino… casei Shirota on skin condition and the gut microbiota: a randomised clinical pilot trial. (gapsfamily.org)
  • It plays a key role in subgingival biofilm formation by bridging the early colonizers (streptococci and actinomyces) and the late colonizers ( Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola ) 3 that make up the red complex initially described by Socransky et al . (nature.com)
  • Dysbiotic communities are characterized by increased numbers of bacteria that exploit the serum-like transudate for nutrients, giving rise to a proteolytic community phenotype. (biomedcentral.com)
  • Together in the subgingival consortium however, all the included species were able to grow in the serum environment and the community adopted a proteolytic phenotype. (biomedcentral.com)
  • E. meningoseptica isolate CH2B and strain NCTC 10016 T displayed a strong biofilm-forming phenotype which may play a role in its potential pathogenicity in both clinical and aquaculture environments. (biomedcentral.com)
  • Actinomyces oris is an early colonizer and has two types of fimbriae on its cell surface, type 1 fimbriae (FimP and FimQ) and type 2 fimbriae (FimA and FimB), which contribute to the attachment and coaggregation with other bacteria and the formation of biofilm on the tooth surface, respectively. (biomedcentral.com)
  • Fungal biofilm-asso- ciated infections are frequently refractory to conventional iensis possesses a readily inducible fluconazole resistance therapy because of resistance to antimicrobial agents. (cdc.gov)
  • Biofilm-associated tor that is associated with nosocomial Candida infections. (cdc.gov)
  • Most manifestations of can- biofilm-associated infections are needed. (cdc.gov)
  • The use of drugs effective in implanted devices are troublesome and the most frequent- combating biofilm-associated infections could lead to major ly encountered. (cdc.gov)
  • One of the most common is oral denture developments in the treatment of fungal implant infections. (cdc.gov)
  • E. meningoseptica is the most significant species for human clinical infections, although E. miricola has been associated with sepsis [ 2 ]. (biomedcentral.com)
  • Dental surgery, oral trauma, urologic or gynecologic surgery, skin infections and intravenous drug use will increase the chances of endocarditis. (datapunk.net)
  • Similar to the effect of gut microbiota on cirrhosis, emerging evidence also suggests that there is a possible link between a dysbiotic oral microenvironment and liver diseases. (jci.org)
  • Tooth-associated communities were distinct, but not entirely dissimilar, from other oral surfaces. (biomedcentral.com)
  • May involve the interaction of phosphate groups with calcium ions in saliva to form "bridges" Protective functions of early enamel pellicle: protection , lubrication by decreasing frictional forces, may selectively concentrate antimicrobial substances such as immunoglobulins, lysozyme, and cystatins at different oral surfaces. (medicpresents.com)
  • The ability of E. meningoseptica isolates to adhere to abiotic surfaces and form biofilm structures may result from the hydrophilic cell surface and multiple adhesins located around the cell. (biomedcentral.com)
  • These organisms colonize tooth surfaces by creating biofilms in the human mouth, also known as dental plaque. (datapunk.net)
  • Here we investigate the contribution of interactions between members of a sub-gingival community to survival and development of virulence in a serum environment-modelling that in the subgingival pocket. (biomedcentral.com)
  • members of the genus also produce a filamentous type of Biofilms are universal, complex, interdependent com- growth (pseudohyphae) (1). (cdc.gov)
  • Eventually dental biofilms lead to periodontal disease and dental cavities which are two of the most common diseases in developed nations.S. gordonii also causes bacterial endocarditis by entering the blood stream usually after oral trauma. (datapunk.net)
  • One of the most significant current discussions in Cu biochemistry relates to the mechanisms of the positive and negative actions of Cu ions based on the generation of reactive oxygen species, including radicals that can interact with DNA molecules. (mdpi.com)
  • Moreover, riboflavin and flavins could produce reactive oxygen species (ROS) when exposed to light, inducing oxidative damage in cells and tissues, and thus are excellent natural photosensitizers. (bioseek.eu)
  • Additionally, research has correlated poor oral heath and the resulting ability of the oral microbiota to invade the body to affect cardiac health as well as cognitive function. (wikipedia.org)
  • Their mechanisms include maintaining physicochemical conditions in the colon (e.g., pH and bile acid profile), balancing the quantity of beneficial gut microbiota members through the production of short-chain fatty acids, reducing the abundance of putrefactive bacteria producing enzymes such as azoreductase, β-glucosidase, β-glucuronidase, and nitroreductase, binding and degrading mutagenic compounds, as well as performing immunomodulatory activities. (metabiom.org)
  • Although the gut microbiota is populated mainly by bacteria, it also contains less than 1% of fungi. (frontiersin.org)
  • La majoria d'articles són en anglès, amb alguns en castellà o altres llengües, y la majoria té resum en castellà, gràcies al Biocodex Microbiota Insitute (que no fa els resums en català). (gapsfamily.org)
  • The recruitment criteria included a set of objective, composite measurements performed by healthcare professionals [ 10 ], defining this reference population and enabling this investigation to focus on defining the integrated oral, oropharyngeal, and gut microbiomes in the absence of host disease. (biomedcentral.com)
  • Dysbiosis of coral microbiomes results from various biotic and environmental stressors, including interactions with important reef fishes which may act as vectors of opportunistic microbes via deposition of fecal material. (frontiersin.org)
  • S gordonii is part of the group viridians of Strepotococci, nonpathogenic commensal streptococci, which are integral members of the human oral flora. (datapunk.net)
  • In the multi-species consortium, growth was facilitated by the wild-type and Rgp-expressing strains of P. gingivalis, suggesting that Rgp is involved in delivery of nutrients to the whole community through degradation of complex protein substrates in serum. (biomedcentral.com)
  • Although C. composed of a population that developed from a single albicans is the predominant etiologic agent of candidiasis, species or a community derived from multiple microbial other Candida species that tend to be less susceptible to the species (14,17). (cdc.gov)
  • Instead, bacteria with the ability to form attachments to the acquired pellicle, which contains certain salivary proteins, on the surface of the teeth, begin the establishment of the biofilm. (wikipedia.org)
  • Organic Component Organic constituents : polysaccharides, proteins, glycoproteins, and lipid material Polysaccharides produced by bacteria-Dextran: predominant form Albumin: originating from crevicular fluid Lipid material: debris from the membranes of disrupted bacterial and host cells and possibly food debris. (medicpresents.com)
  • In bacteria and archaea , structural proteins with related functions are usually encoded together within the genome in a block called an operon and are transcribed together under the control of a single promoter , resulting in the formation of a polycistronic transcript ( Figure 12.30 ). (pressbooks.pub)
  • In recombinant DNA technology, DNA molecules are manipulated using naturally occurring enzymes derived mainly from bacteria and viruses. (pressbooks.pub)
  • Additionally, we identified a clear, significant enrichment of predicted virulence-associated genes in the colorectal cancer microenvironment, likely dependent upon the genomes of Fusobacterium and Providencia . (biomedcentral.com)
  • Candida species, including the novel opportunistic cans many virulence factors, such as germ tube formation, pathogen Candida dubliniensis , are now emerging as exoenzyme production, and phenotypic switching (10). (cdc.gov)
  • Bacteria occupy the ecological niche provided by both the tooth surface and mucosal epithelium. (wikipedia.org)
  • #Bifidobacterium is associated with antitumor effects, and oral administration of #Bifidobacterium alone improved tumor control to the same degree as PD-L1 antibody therapy while combination treatment nearly abolished tumor growth in mice. (metabiom.org)
  • Analysis showed that the gut bacterial composition of samples from HwA was less diverse than that of samples from HwoA and had a lower abundance of Roseburia , Barnesiella , Butyricicoccus , Odoribacter , and Butyricimonas species, most of which were short-chain fatty acids-producing microbes. (frontiersin.org)
  • Compared with those in samples from HwoA, the abundance correlation networks in samples from HwA displayed more complex fungal-fungal and fungal-bacterial community interactions. (frontiersin.org)
  • A dynamic equilibrium exists between dental plaque bacteria and the innate host defense system. (wikipedia.org)
  • Early childhood caries (ECC) - dental caries (cavities) occurring in primary teeth up to age 6-years - is a prevalent childhood oral disease with a microbial etiology. (researchsquare.com)
  • Formation of dental Pellicle Acquired enamel pellicle forms rapidly - Early pellicle Characterized by an absence of bacteria and their products. (medicpresents.com)
  • Short-chain fatty acids (SCFAs) are metabolic products of oral bacteria including A. oris and regulate pH in dental plaques. (biomedcentral.com)
  • SCFAs affect the INAC-associated activities of the A. oris fimbrillins and non-fimbrillins during ionized and non-ionized acid formations in the form of co-culturing with other bacteria in the dental plaque but not impact the interaction of A. oris with streptococci. (biomedcentral.com)
  • It can be a social problem in which standard dental treatments and mouthwashes are often recommended to manage oral causes and provide relief that often needs consistent maintenance. (medscape.com)
  • 1, 2 This review approaches the role of mucin degrading enzymes from the potential interaction of micro-organisms with the cervical mucus barrier, and discusses the contribution that mucin degrading enzymes may make to microbial colonisation of the reproductive tract. (bmj.com)
  • Candida biofilms include those occurring on devices such and in infected patients, strongly suggesting that C. dublin- as indwelling intravascular catheters. (cdc.gov)
  • Candida biofilms are highly relevant for public health (4,7,15-18). (cdc.gov)
  • Speculations about the ecologic advan- commonly used antifungal drugs such as C. krusei , C. tages of forming a biofilm include protection from the glabrata , C. lusitaniae , and the newest Candida species, environment, nutrient availability, metabolic cooperation, C. dubliniensis, have emerged as substantial opportunistic and acquisition of new genetic traits (3,17). (cdc.gov)
  • This study revealed a marked impact of appendectomy on gut bacteria and fungi, which was particularly durable for fungi. (frontiersin.org)
  • The gingival crevice area (supporting structures of the teeth) provides a habitat for a variety of anaerobic species. (wikipedia.org)
  • At junctional epithelium the teeth provide access to bacteria into the body. (medicpresents.com)
  • About 80-90% of halitosis is due to intraoral microbial species that populate on the tongue, teeth, and periodontal biofilms. (medscape.com)
  • However, interactions between these biotic and abiotic factors have yet to be evaluated. (frontiersin.org)
  • isolates, while the role of cell-free supernatants, from diverse bacteria, in inducing enhanced adherence was investigated using microtitre plate assays. (biomedcentral.com)
  • Bacterial vaginosis (BV), or nonspecific vaginitis, was named because bacteria are the etiologic agents and an associated inflammatory response is lacking. (medscape.com)
  • Understanding the interaction between the gene expression of a pathogen and that of its human host is important for the understanding of a particular infectious disease. (pressbooks.pub)
  • Given the emergence of antibiotic-resistant bacteria, new, preferably inexpensive, alternatives to conventional antibiotics must be developed. (nature.com)
  • Treatment consists of intravenous antibiotic therapy and sometimes oral antibiotics for several weeks. (datapunk.net)
  • Nugent's criteria may be used to quantify or grade bacteria via Gram staining of vaginal samples. (medscape.com)
  • It is curious that oral streptococci are efficient in binding to blood platelets especially since the blood stream is not their natural habitat. (datapunk.net)
  • Recent studies have addressed this phenomenon and concluded that oral streptococci have adapted specialized mechanisms to recognize and bind with sialic-acid containg structures in the mouth, their natural habitat, which also allows for efficient interaction with platelet sialoglycoprotein GPI-alpha, located on the platelet membrane. (datapunk.net)
  • Clearly, an evolutionary adaptation in one habitat has allowed S. gordoniiand other oral streptococci to invade another habitat .Bacterial endocarditis occurs in humans who most often have artificial heart valves, heart disorders, or hypertrophic cariomyopathy. (datapunk.net)
  • Studying the microbial communities in the tumor microenvironment may shed light on the role of host-bacteria interactions in colorectal cancer. (biomedcentral.com)
  • therefore, this review will highlight the emerging role of the oral-gut-liver axis and introduce perspectives for future research. (jci.org)
  • The role of volatile sulfur compounds (VSCs) in producing bacteria that colonize the dorsal surface of the tongue was recently understood as a primary cause of halitosis (bad breath). (medscape.com)
  • Oral malodor from the overgrowth of proteolytic, anaerobic gram-negative bacteria on the crevices of the tongue dorsum can be successfully diagnosed and treated. (medscape.com)
  • Intragenera competitions and intergenera cooperation between oral taxa may shape the emergence of these communities, providing points for preventive interventions. (researchsquare.com)