Injection autoinjector anaphylaxis. Medical search. Frequent questions

It's a brand-name prescription medication used in adults and some children for the emergency treatment of severe allergic reactions , including anaphylaxis . (medicalnewstoday.com)
Epinephrine injection, USP auto-injector is a non-selective alpha and beta-adrenergic receptor agonist indicated in the emergency treatment of allergic reactions (Type I) including anaphylaxis. (nih.gov)
Auvi-Q is the first and only compact epinephrine auto-injector for severe allergic reactions (anaphylaxis) that will talk you through the injection. (mountainside-medical.com)
The Epinephrine Injection, USP Auto-Injector is indicated in the emergency treatment of allergic reactions (TYPE I) including anaphylaxis to stinging and biting insects, food, drugs, allergen immunotherapy, diagnostic testing substances, and other allergens, as well as idiopathic or exercise-induced anaphylaxis. (epinephrineautoinject.com)
Serious allergic reactions, including anaphylaxis: Permanently discontinue UDENYCA in patients with serious allergic reactions. (drugs.com)
Emerade is indicated for the emergency treatment of severe acute allergic reactions (anaphylaxis) triggered by allergens in foods, medicines, insect stings or bites, and other allergens as well as for exercise-induced or idiopathic anaphylaxis. (medicines.org.uk)
Epinephrine injection is used to treat severe allergic reactions (anaphylaxis) to insect stings or bites, foods, drugs, and other allergens. (canpharm.com)
Children with severe allergic reactions must be carefully guarded from the source of their allergies if they even potentially suffer anaphylaxis, as allergic reactions can happen any time and at any age. (pediatricmalpracticeguide.com)
Background: Anaphylaxis is the most severe clinical presentation of acute systemic allergic reactions and can cause death. (bvsalud.org)

The diagnosis and long-term management of anaphylaxis are complicated, so you'll probably need to see a doctor who specializes in allergies and immunology. (nchmd.org)
Our data show that the level of pediatricians' knowledge about recent advances in the management of anaphylaxis is unsatisfactory. (turkishjournalpediatrics.org)
Pediatricians' failure to know recent advances in the management of anaphylaxis may endanger children when assistance is required. (turkishjournalpediatrics.org)
However, management of anaphylaxis - both acute and preventative - varies by region. (bvsalud.org)
Methods: The World Allergy Organization (WAO) Anaphylaxis Committee and the WAO Junior Members Steering Group undertook a global online survey to evaluate local practice in the diagnosis and management of anaphylaxis across regions. (bvsalud.org)

Patients with refractory or very severe anaphylaxis (with cardiovascular and/or severe respiratory symptoms) should be admitted or treated and observed for a longer period in the emergency department or an observation area. (medscape.com)
6 , 7 Three clinical criteria for anaphylaxis based on symptoms and history were also proposed at the symposium. (aap.org)
The symptoms of anaphylaxis can signal that urgent medical attention is required. (medicalnewstoday.com)
Someone with anaphylaxis may have other symptoms too, such as skin reactions, stomach pains, and vomiting. (bupa.co.uk)
Adrenaline is the most effective drug for anaphylaxis symptoms. (bupa.co.uk)
Anaphylaxis symptoms usually occur within minutes of exposure to an allergen. (nchmd.org)
Even if symptoms improve after the injection, you still need to go to an emergency room to make sure symptoms don't recur, even without more exposure to the allergen. (nchmd.org)
Make an appointment to see your provider if you or your child has had a severe allergy attack or signs and symptoms of anaphylaxis in the past. (nchmd.org)
Allergy symptoms aren't usually life-threatening, but a severe allergic reaction can lead to anaphylaxis. (nchmd.org)
If symptoms reoccur after the first injection, a repeat injection can be given after 10-20 minutes while en route to emergency care. (anaphylaxis.org)
Anaphylaxis might start with some of the same symptoms as a less severe reaction, but can quickly get worse. (kidshealth.org)
This online course will introduce you to the signs and symptoms of anaphylaxis. (guardiangroupservices.com)
While we usually write about common food allergy symptoms, such as diarrhea or eczema, more severe reactions like anaphylaxis are possible for many children and adults with allergies. (neocate.com)
Administering the medication to someone who does not show symptoms of anaphylaxis. (outdooreducation.in)
An initial dose should be administered as soon as symptoms of anaphylaxis are recognised. (medicines.org.uk)
They should call for immediate medical assistance, ask for an ambulance and state 'anaphylaxis' even if symptoms appear to be improving (see section 4.4) . (medicines.org.uk)
Based on recommendations from an expert group, the symptoms and values from Sampson5 were for all reactions and anaphylaxis only translated and compared by kappa statistics with 22 instruments, ranging from 3 to 6 steps. (worldallergy.org)
Symptoms can range from mild to severe, ranging from a simple rash to anaphylaxis (rare cases). (buzzymoment.com)
Adrenaline reverses the symptoms of anaphylaxis by acting on alpha and beta adrenergic receptors in the body. (olicentral.com)
If your child seems to be suffering from a severe reaction (so an intense culmination of mild to moderate symptoms) or anaphylaxis, seek medical attention immediately. (healthstoriesforkids.com)
Although most children suffer from the common symptoms of an egg allergy, on some occasions, anaphylaxis can happen. (foodallergyinstitute.com)
One time your child may have mild symptoms, but next time it can be more severe or even lead to anaphylaxis. (foodallergyinstitute.com)

In some cases, the cause of anaphylaxis is not identified (idiopathic anaphylaxis). (nchmd.org)
At-risk patients include "those with a history of anaphylaxis who can re-encounter their triggers, such as foods or stinging insects, those with idiopathic anaphylaxis, and those at increased risk of anaphylaxis who might not yet have experienced it. (medscape.com)

Epinephrine injection, USP auto-injectors are intended for immediate administration in patients who are determined to be at increased risk for anaphylaxis, including individuals with a history of anaphylactic reactions. (nih.gov)
Epinephrine injection, USP auto-injectors are intended for immediate administration as emergency supportive therapy only and are not a substitute for immediate medical care. (nih.gov)
Prefilled injectable epinephrine pens and adrenaline auto injectors are anticipated to witness a hike in sales owing to the high ubiquity of allergic conditions such as anaphylaxis on a global level. (factmr.com)
Epinephrine auto-injectors may be kept on hand for self-injection by a person with a history of severe allergic reaction. (canpharm.com)
Epinephrine auto-injectors, commonly known as Epipens, are life-saving devices used to treat anaphylaxis, a severe allergic reaction that can be fatal if left untreated. (sigfox.us)
Even with the rise of other epinephrine auto-injectors in the market, the EpiPen continues to be the leading device for emergency treatment of anaphylaxis in the United States. (sigfox.us)
According to a new study published in the Annals of Allergy, Asthma and Immunology , the scientific publication of the American College of Allergy, Asthma and Immunology (ACAAI), misuse of epinephrine auto-injectors has been documented in cases of fatal anaphylaxis. (kidswithfoodallergies.org)
It includes information about epinephrine auto-injectors (available in the US), how epinephrine treats anaphylaxis, how to use your auto-injector, and other key facts about the drug. (kidswithfoodallergies.org)
Failure to use auto injectors at the right time is mainly due to lack of knowledge about signs of anaphylaxis. (pharmiweb.com)
The SHL Group offers a variety of auto injectors that can accommodate changes in injections, such as larger volumes, high viscosity and others. (pharmiweb.com)

Epinephrine is also used to treat exercise-induced anaphylaxis, or to treat low blood pressure that is caused by septic shock. (canpharm.com)

In rare cases, severe mosquito bite allergies can lead to anaphylaxis, a life-threatening allergic reaction. (emoyer.com)

however, at a recent symposium cosponsored by the National Institutes of Health and the Food Allergy & Anaphylaxis Network, the following definition was proposed: "Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death. (aap.org)
Even if you or your child has had only a mild anaphylactic reaction in the past, there's a risk of more severe anaphylaxis after another exposure to the allergy-causing substance. (nchmd.org)
Peanut allergy can cause a severe reaction called anaphylaxis , even if a previous reaction was mild. (kidshealth.org)
If you have already had a severe reaction/anaphylaxis , wear a medical alert bracelet or necklace that will alert others and you have a food allergy. (allergycure.co.in)
This plan should include the appropriate management strategies to care the child in case of food allergy and in emergency case of anaphylaxis. (allergycure.co.in)
An EpiPen Auto-Injector has been a mandatory part of my backcountry first aid kit for over a decade, as I have an undiagnosed allergy that leads to anaphylaxis. (backpackgeartest.org)
One hundred and fifty-two cases of severe anaphylaxis were reported to the Allergy Vigilance Network in France and Belgium in 2011. (biomedcentral.com)
Arroabarren E, Lasa EN: Pediatr Allergy Immunol. (biomedcentral.com)
Beyond anaphylaxis, the immune system's reaction to egg allergy can lead to other health complications. (buzzymoment.com)
Your doctor can prescribe your child an epinephrine autoinjector if they are diagnosed with a peanut allergy. (healthstoriesforkids.com)
The consequences of an unknown and serious allergy can be life-altering, since anaphylaxis requires emergency treatment, often in a hospital . (pediatricmalpracticeguide.com)
Further, a number of patients visiting the emergency department due to severe anaphylaxis reaction are already administered epinephrine, says the Journal of Allergy and Clinical Immunology. (pharmiweb.com)
The AAP's universal Allergy and Anaphylaxis Emergency Plan offered in this report is available on the AAP website . (medscape.com)

Designs exist for both intramuscular and subcutaneous injection. (wikipedia.org)
Intramuscular injection of epinephrine into the lateral thigh (vastus lateralis) is the preferred route for therapy in first-aid treatment. (aap.org)
Include the proper use of epinephrine auto-injector to ensure that subcutaneous or intramuscular injections are given into the anterolateral aspect of the thigh, including through clothing if necessary. (epinephrineautoinject.com)
These injections are typically less painful than intramuscular injections, which go into the muscle (requiring longer needles) ( Usach, 2019 ). (ro.co)
Compared to intramuscular or intravenous (into a vein) injections, subcutaneous injections deliver medications more slowly, which is important for certain medications. (ro.co)
The EpiPen Auto-Injector is a prescription device that delivers an intramuscular 0.3 mg epinephrine dose to a person suffering anaphylaxis (allergic emergencies). (backpackgeartest.org)
While intramuscular epinephrine (adrenaline) is first-line treatment for anaphylaxis, some countries continue to recommend alternative routes in contrast to guidelines. (bvsalud.org)

There's a whole range of things that can cause anaphylaxis. (bupa.co.uk)
Additionally, if you have allergies that cause anaphylaxis, such as bee stings or certain food allergies, you will want to ask your allergist for an additional epinephrine injection prescription. (greenbarnllamafarm.com)

Effective care for individuals at risk of anaphylaxis requires a comprehensive management approach involving families, allergic children, schools, camps, and other youth organizations. (aap.org)

Risk reduction entails confirmation of the trigger, discussion of avoidance of the relevant allergen, a written individualized emergency anaphylaxis action plan, and education of supervising adults with regard to recognition and treatment of anaphylaxis. (aap.org)
When an allergen couples with the IgE antibodies, histamine and other mediators of anaphylaxis are released from the mast cells and basophils. (anaphylaxis.org)
When anaphylaxis happens as a result of contact with an allergen, a rapid immune reaction occurs that can quickly make breathing very difficult. (neocate.com)
Our doctors will prescribe injections with increasing amounts of the allergen to allow your body to build immunity. (mcgovernallergy.com)

Anaphylaxis is an acute, potentially fatal, multiorgan system reaction caused by the release of chemical mediators from mast cells and basophils. (medscape.com)
Anaphylaxis is an acute, life-threatening reaction, usually mediated by an immunologic mechanism involving immunoglobulin E, that results in sudden systemic release of mast-cell and basophil mediators such as histamine and tryptase. (aap.org)

But the most common anaphylaxis triggers include the following. (bupa.co.uk)

If the person has a history of severe reactions, they may be carrying an adrenaline, or epinephrine, injection kit. (medicalnewstoday.com)
If you have an ongoing risk of anaphylaxis, you should be prescribed an adrenaline auto-injector (or 'pen'), like EpiPen, Emerade or Jext. (bupa.co.uk)
Have an Epinephrine / Adrenaline Autoinjector with you. (allergycure.co.in)
A poor outcome from anaphylaxis is associated with late administration of adrenaline. (medicines.org.uk)
This severe reaction requires an immediate epinephrine (adrenaline) injection and a visit to the emergency room. (foodallergyinstitute.com)
The drug, a man-made version of adrenaline, a hormone made by our bodies, is used to counter a potentially life-threatening allergic reaction known as anaphylaxis. (medscape.com)

People who know they are at risk of anaphylaxis should always carry an epinephrine auto-injector with them and should know how to use it. (safemedicationuse.ca)
If you have an attack and you carry an epinephrine autoinjector, administer it right away. (nchmd.org)

In 2023 an open source autoinjector was developed that could be digitally replicated with a low cost desktop 3D printer. (wikipedia.org)

In a person experiencing anaphylaxis, the airways often become narrow, making breathing difficult. (medicalnewstoday.com)

Mere minutes in a case of anaphylaxis can cost a child their life. (pediatricmalpracticeguide.com)

[ 3 ] It is also important to note that some of the most severe cases of anaphylaxis present in the absence of skin findings. (medscape.com)
The studies brought together 22,313 anaphylaxis episodes for the severity studies and 18,101 anaphylaxis episodes for the studies of new cases of anaphylaxis. (worldallergy.org)

An anaphylactic reaction (also known as anaphylaxis) is a serious allergic reaction that can come on quickly and may cause death. (safemedicationuse.ca)
EpiPens are auto-injectable devices, which are intended to deliver epinephrine to individuals experiencing a severe allergic reaction, known as anaphylaxis. (aboutlawsuits.com)

See Table 1 for a side by side comparison of presenting features of anaphylaxis and vasovagal syncope. (canada.ca)
Therefore, a sudden loss of consciousness in young children should be presumed to be anaphylaxis , especially if other clinical features of anaphylaxis are present. (canada.ca)
Table 1: Key distinguishing features of anaphylaxis and vasovagal syncope. (canada.ca)

Although a variety of different triggers for anaphylaxis episodes have been identified, food and insect stings are the most common identifiable triggers reported in the community setting. (aap.org)
What are the most common triggers for anaphylaxis? (bupa.co.uk)

What is the best treatment for anaphylaxis? (anaphylaxis.org)

What is a subcutaneous injection? (ro.co)
A subcutaneous injection-also called a sub-Q or SQ injection-goes just under the skin and into that layer of fat above the muscle. (ro.co)
There are several common subcutaneous injection sites, all of which are places on the body with a layer of fatty tissue under the skin. (ro.co)
Glatopa is a clear, colorless to slightly yellow, sterile, nonpyrogenic solution for subcutaneous injection. (rxlist.com)

The medicine epinephrine is used to treat anaphylaxis and should be given as soon as possible. (safemedicationuse.ca)
Epinephrine injection is the medication that is used to treat anaphylaxis. (guardiangroupservices.com)

Most live with them without life-threatening episodes, perhaps with annoying sniffles, watery eyes, or itchy rashes-unless they experience anaphylaxis. (pediatricmalpracticeguide.com)

Yet another type of injection device is called an autoinjector, best known with EpiPens, a quick-jab method of delivering epinephrine into the muscle for people having a severe allergic reaction ( Campbell, 2016 ). (ro.co)

When a person experiences anaphylaxis it is also called an anaphylactic shock . (outdooreducation.in)
It is given by injection to treat a life-threatening allergic reaction called anaphylactic shock. (olicentral.com)

Brand names include Anapen, EpiPen, Emerade, and Auvi-Q. Rebiject, Rebiject II and Rebidose autoinjectors for Rebif, the drug for interferon beta-1a used to treat multiple sclerosis. (wikipedia.org)
Glatopa (glatiramer acetate injection) is an immunomodulator used to treat patients with relapsing forms of multiple sclerosis (MS), including those who have experienced a first clinical episode and have magnetic resonance imaging (MRI) features consistent with MS. Glatopa is generic version of Copaxone . (rxlist.com)

This involves regular injections of small amounts of allergens to help the body build up a tolerance over time. (emoyer.com)

2 - 4 Food allergies 5 and other allergies have increased in the past several years, and pediatricians increasingly need to prescribe emergency care plans for patients in the event of anaphylaxis outside the hospital/medical setting. (aap.org)
Egg allergies can cause a severe reaction called anaphylaxis . (kidshealth.org)

An EpiPen is an autoinjector (automatic injection device). (medicalnewstoday.com)
EpiPen also comes with a trainer autoinjector ("dummy" EpiPen). (medicalnewstoday.com)
You can use it to practice giving an EpiPen injection. (medicalnewstoday.com)
If you're administering EpiPen to a child, it's important to hold their leg firmly during the injection. (medicalnewstoday.com)
This Anaphylaxis and Epipen certificate provides a record of your training history and course completion. (guardiangroupservices.com)

Anaphylaxis is a severe, potentially fatal systemic allergic reaction that is rapid in onset and may cause death. (aap.org)
If anaphylaxis isn't treated right away, it can be fatal. (nchmd.org)

The recommended epinephrine dose for anaphylaxis in children, based primarily on anecdotal evidence, is 0.01 mg/kg, up to 0.30 mg. (aap.org)

Anaphylaxis is primarily a clinical diagnosis. (medscape.com)
This clinical report focuses on practical issues concerning the administration of self-injectable epinephrine for first-aid treatment of anaphylaxis in the community. (aap.org)
1 Anaphylaxis has many clinical presentations, but respiratory compromise and cardiovascular collapse cause the greatest concern, because they can potentially lead to fatalities. (aap.org)
Table 1 lists clinical features that differentiate fainting due to vasovagal syncope from anaphylaxis. (canada.ca)
This has impact upon clinical practice, and whether to withhold these types of medications in patients at risk of anaphylaxis or even prior to some common procedures, such as diagnostic challenges. (worldallergy.org)
Table 1 Clinical features of severe food anaphylaxis treated by epinephrine. (biomedcentral.com)

Emerade should be administered early, at the first signs of anaphylaxis. (medicines.org.uk)

An autoinjector for the Avonex version of this same medication is also on the market. (wikipedia.org)
Injection of affected medication could also result in increased irritation or reaction at the injection site. (productsafety.gov.au)
For instance, in the case of an insulin injection for diabetes, slower medication delivery means a more effective and even control of blood sugar. (ro.co)
Your healthcare provider will go over the specifics for your particular medication, including how to store the medication (in the refrigerator or at room temperature), the dosage, when to inject, and details about the injection device you'll be using. (ro.co)
There are also pen-like injection devices that deliver medication with the click of a button ( FDA, 2013 ). (ro.co)
Our Glatopa (glatiramer acetate injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
The American Academy of Pediatrics (AAP) confirms in a new report that epinephrine is the medication of choice for the first-aid treatment of anaphylaxis and updates a 2007 report on how it should be used most effectively. (medscape.com)

On rare occasions, a life-threatening reaction called anaphylaxis can happen. (foodallergyinstitute.com)
However, people who are severely allergic can have a life-threatening reaction called Anaphylaxis. (mcgovernallergy.com)

When triggered the actuator drives a three-step sequence: accelerate the syringe forward, puncturing the injection site actuate the piston of the syringe, injecting the drug deploy a shield to cover the needle Some injectors are triggered by simply pushing the nose ring against the injection site. (wikipedia.org)
Glatopa is for subcutaneous use only using the prefilled syringe or an optional injection device [see Instructions For Use ]. (rxlist.com)
Outside healthcare settings, epinephrine autoinjectors (EAs) are preferred because they are relatively easy to use and have more reliable accuracy of dosing than laypeople filling a syringe or using a prefilled syringe, the report says. (medscape.com)

An autoinjector (or auto-injector) is a medical device designed to deliver a dose of a particular drug. (wikipedia.org)
The autoinjector contains a single dose of the drug for injection into the thigh. (medicalnewstoday.com)
Each device is a single-dose injection. (nih.gov)
This report also describes several quandaries in regard to management, including the selection of dose, indications for prescribing an autoinjector, and decisions regarding when to inject epinephrine. (aap.org)
6 mg/0.6 mL in a single-dose prefilled autoinjector. (drugs.com)
Included in the epinephrine guidance is the recommendation that if anaphylaxis occurs in a healthcare setting, epinephrine should be given in these doses: 0.01 mg/kg (maximum dose, 0.3 mg) in a prepubescent child, and up to 0.5 mg in a teenager. (medscape.com)

SureClick autoinjector is a combination product for drugs Enbrel or Aranesp to treat rheumatoid arthritis or anemia, respectively. (wikipedia.org)

The site of injection depends on the drug loaded, but it typically is administered into the thigh or the buttocks. (wikipedia.org)
The epinephrine injection, USP auto-injector should ONLY be injected into the anterolateral aspect of the thigh. (epinephrineautoinject.com)
The outer thigh is the safest site for injection because there are no major blood vessels or nerves in this area. (anaphylaxis.org)
The drug's effects typically last ten to twenty minutes and it is administered by self injection into the outer thigh, and keeping the needle depressed for ten seconds. (backpackgeartest.org)
Other common errors included failure to place the needle end of the device on the thigh, and failure to push down forcefully enough to activate the injection. (kidswithfoodallergies.org)

Anaphylaxis is a severe systemic allergic reaction that causes the bronchi (in the respiratory system) to constrict and blood vessels to dilate. (outdooreducation.in)

Anaphylaxis is a severe, potentially life-threatening allergic reaction. (nchmd.org)

Large doses or accidental intravenous injection of epinephrine may result in cerebral hemorrhage due to a sharp rise in blood pressure. (epinephrineautoinject.com)

This second reaction is called biphasic anaphylaxis. (nchmd.org)
In severe cases, this reaction is called anaphylaxis. (guardiangroupservices.com)

Naloxone autoinjectors are being developed and prescribed to recreational opioid users to counteract the deadly affects of opioid overdose. (wikipedia.org)
People with a prescription for a naloxone injection kit, automatic injection device, or nasal spray should train on how to administer it properly. (cdc.gov)

Epinephrine autoinjectors are often prescribed to people who are at risk for anaphylaxis. (wikipedia.org)
To minimize the risk of injection related injury, hold the child's leg firmly in place and limit movement prior to and during injection when administering to young children. (nih.gov)
In addition to being relatively painless, SQ injections are easy to do at home, and the small needle size means the risk of infections is low (Usach, 2019). (ro.co)
Beta-blockers (BBs) and angiotensin-converting enzyme inhibitors (ACEIs) have been associated with an increased risk and severity of anaphylaxis. (worldallergy.org)
When the doctor considers that there is a high risk of anaphylaxis, an emergency injection of epinephrine may be ordered. (buzzymoment.com)
Medical providers can prescribe an epinephrine auto-injector for a child at risk of a severe allergic reaction ( anaphylaxis ). (healthychildren.org)
Epinephrine auto-injector (EAI) devices, prescribed to individuals at ongoing risk of anaphylaxis in the community setting, are only available in 60% of countries surveyed, mainly in high-income countries. (bvsalud.org)
Learn how to use an epinephrine auto-injector if you, a family member, or a coworker is at risk for anaphylaxis. (cdc.gov)

They offer the added benefit of being a straightforward way for people who need frequent injections to get their medicine at home without visiting a healthcare provider. (ro.co)
If you are giving yourself or another person daily or weekly injections, your healthcare provider may recommend switching up your injection site each time or positioning the needle at least one inch away from the last place you injected. (ro.co)
Likewise, if you're helping someone else with their injections, follow their healthcare provider's exact instructions. (ro.co)
Given the prevalence of anaphylaxis within healthcare systems, it is a high priority public health issue. (bvsalud.org)

The quality of evidence showing that the use of BBs and ACEI increases the severity of anaphylaxis is low owing to differences in the control of confounders arising from the concomitant presence of cardiovascular diseases. (worldallergy.org)

Anatomy2

Organisms8

Diseases14

Chemicals and Drugs27

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Phenomena and Processes4

Technology, Industry, Agriculture2

Allergic Reactions9

Management of Anaphylaxis5

Symptoms22

Idiopathic anaphylaxis2

Auto-injectors10

Exercise-induced ana1

Lead to anaphylaxis1

Allergy13

Intramuscular7

Cause anaphylaxis2

Individuals at risk of anaphylaxis1

Allergen4

Acute2

Common anaphylaxis triggers1

Adrenaline6

Carry an epinephrine2

20231

Person experiencin1

Case of anaphylaxis1

Cases of anaphylaxis2

Known as anaphylaxis2

FEATURES OF ANAPHYLAXIS3

Triggers for anaphylaxis2

Treatment for anaphylaxis1

Subcutaneous injection4

Treat anaphylaxis2

Experience anaphylaxis1

Having a severe allergic reaction1

Anaphylactic Shock2

Multiple sclerosis2

Allergens1

Allergies2

EpiPen5

Fatal2

Epinephrine dose1

Clinical6

Emerade1

Medication7

Life-threatening rea2

Syringe3

Dose6

Rheumatoid arthritis1

Thigh5

Systemic allergic reaction1

Potentially1

Intravenous1

Reaction is called2

Naloxone2

Risk8

Healthcare4

Cardiovascular1