Liposome injectionChemotherapyEffects of vincristineAdministration of vincristineSulfate liposomeReceive vincristineIntrathecal vincristineMedicationSodium Chloride InjectionAcute lymphoblOxaliplatin InjectionIsolated in 1961Injected intravenouslyDoxorubicinDoseBelongsAllergicKrisDrugsVein100mgMercaptopurinePeripheral neuropathyAntineoplastic agentVinlon 1mg InjectionCancerTreatmentsTubulinConstipationNauseaBleomycinCyclophosphamideInterferePatientsDextrose InjectionTabletsMedicationsInteractionsRatsWater for InjectionDrugTreatmentAccidentalSide effects
Liposome injection3
- Marqibo® (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine. (nih.gov)
- Vincristine liposome injection is used to treat Philadelphia chromosome-negative acute lymphoblastic leukemia (Ph- ALL) that has worsen or come back or in patients who have received at least 2 previous cancer treatments that did not work well. (mayoclinic.org)
- This medication comes in a liposome injection as well as an injection to be given directly into a vein (IV) by a healthcare provider. (medicap.com)
Chemotherapy8
- Vincristine lipid complex should be given only under the supervision of a doctor with experience in the use of chemotherapy medications. (medlineplus.gov)
- Vincristine, also known as leurocristine and marketed under the brand name Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer. (wikipedia.org)
- Vincristine is delivered via intravenous infusion for use in various types of chemotherapy regimens. (wikipedia.org)
- The main side effects of vincristine are chemotherapy-induced peripheral neuropathy, hyponatremia, constipation, and hair loss. (wikipedia.org)
- Chemotherapy-induced peripheral neuropathy can be severe, and may be a reason to reduce or avoid using vincristine. (wikipedia.org)
- The chemotherapy drug vincristine almost always causes fatal toxicity if it is incorrectly administered intrathecally (via spinal injection) rather than intravenously. (ahrq.gov)
- ZOFRAN® Injection is indicated for the prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy, including high-dose cisplatin [see Clinical Studies ]. (globalrph.com)
- Before having acute myeloid leukemia, the patient received 6 cycles of combination chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, etoposide, and prednisone) to treat high-grade diffuse large B cell lymphoma. (cdc.gov)
Effects of vincristine1
- Nervous system effects may be more likely to occur in the elderly, who are usually more sensitive to the effects of vincristine. (drugs.com)
Administration of vincristine2
- For example, many institutions have still not followed best practices for the administration of vincristine. (ahrq.gov)
- Peripheral neuropathy was induced in rats by administration of vincristine sulfate (50 μg/kg i.p. ) for 10 consecutive days. (biomedcentral.com)
Sulfate liposome1
- Patients receive volasertib intravenously (IV) over 1 hour on day 1 and vincristine sulfate liposome IV over 1 hour on days 1, 8, 15, and 22. (mycancergenome.org)
Receive vincristine2
- Your doctor may not want you to receive vincristine lipid complex or may need to change your dose of vincristine lipid complex injection. (medlineplus.gov)
- If you miss an appointment to receive vincristine, contact your doctor as soon as possible to reschedule your appointment. (medbroadcast.com)
Intrathecal vincristine2
- A significant series of inadvertent intrathecal vincristine administration occurred in China in 2007 when batches of cytarabine and methotrexate (both often used intrathecally) manufactured by the company Shanghai Hualian were found to be contaminated with vincristine. (wikipedia.org)
- This hazard is well publicized, but accidental administration of intrathecal vincristine continues to occur. (ahrq.gov)
Medication2
- Medication safety and the administration of intravenous vincristine: international survey of oncology pharmacists. (ahrq.gov)
- Paclitaxel 30 mg Injection is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer. (pharmatone.in)
Sodium Chloride Injection2
- ZOFRAN Injection should be diluted in 50 mL of 5% Dextrose Injection or 0.9% Sodium Chloride Injection before administration. (globalrph.com)
- Irinotecan hydrochloride injection is intended for dilution with 5% Dextrose Injection, USP (D5W), or 0.9% Sodium Chloride Injection, USP, prior to intravenous infusion. (com.bd)
Acute lymphobl1
- Vincristine has been use in combination with other medicines to treat the following cancers: non-Hodgkin's lymphoma, Hodgkin's lymphoma, acute lymphoblastic leukemia (ALL), Wilms' tumor (a form of pediatric kidney cancer), rhabdomyosarcoma, and neuroblastoma. (medicap.com)
Oxaliplatin Injection5
- Salvavidas Pharmaceutical Pvt Ltd is a leading supplier and exporter of Oxaliplatin Injection 50 mg in various strengths And packaging. (salvavidaspharma.com)
- Oxaliplatin injection of 50 mg is used to treat colon and rectal cancer. (salvavidaspharma.com)
- How Does Oxaliplatin Injection 50 mg Work? (salvavidaspharma.com)
- Oxaliplatin injection of 50 mg is an anticancer drug. (salvavidaspharma.com)
- Oxaliplatin Injection 50 mg also treats and reduces the risk of developing additional cancerous growth (polyps) and colon cancer. (salvavidaspharma.com)
Isolated in 19611
- Vincristine was first isolated in 1961. (wikipedia.org)
Injected intravenously1
- Vincristine lipid complex comes as a liquid to be injected intravenously (into a vein) over 1 hour by a doctor or nurse in a medical facility. (medlineplus.gov)
Doxorubicin1
- Three of 14 wipe samples were positive for cyclophosphamide (1.6-3.9 ng/sample) while simultaneously being ND for doxorubicin, vincristine, methotrexate, and epirubicin. (cdc.gov)
Dose3
- The recommended dose and dosing schedule of vincristine varies according to the specific type of cancer being treated, the response to therapy, and the other drugs or treatments being used. (medbroadcast.com)
- Vincristine-induced neuropathy is the main dose-limiting side effect. (wikipedia.org)
- If extravasation occurs, the injection should be discontinued immediately, and any remaining portion of the dose should then be introduced into another vein. (drugs.com)
Belongs3
- Vincristine belongs to the group of cancer-fighting medications known as antineoplastics . (medbroadcast.com)
- Vincristine belongs to the group of medicines known as antineoplastic agents. (drugs.com)
- Vincristine belongs to a group of drugs called vinca alkaloids. (medicap.com)
Allergic1
- tell your doctor and pharmacist if you are allergic to vincristine, any other medications, or any of the ingredients in vincristine lipid complex injection. (medlineplus.gov)
Kris1
- VINCRISTINE (vin KRIS teen) treats some types of cancer. (chemocare.com)
Drugs1
- Chemotherapeutic drugs such as vincristine, paclitaxel, oxaliplatin, etc. are widely used in management of cancers especially Hodgkins lymphoma, non-Hodgkins lymphoma and leukemia. (biomedcentral.com)
Vein5
- Vincristine lipid complex should be administered only into a vein. (medlineplus.gov)
- Vincristine is injected into a vein through a specially prepared site on your skin that has been prepared for this purpose. (medbroadcast.com)
- It is extremely important that the intravenous needle delivering vincristine be properly positioned in the vein. (medicap.com)
- Vinlon 1mg Injection is given as an injection into the vein beneath near the supervision of a health practitioner. (jindalmedicalstore.in)
- [3] If vincristine is used alone, it is given once a week strictly into a vein. (mdwiki.org)
100mg3
- Offering you a complete choice of products which include bevacizumab injection 100mg, paclitaxel 30 mg injection, paclitaxel 100 mg injection, paclitaxel 260mg injection, taxonab paclitaxel protein bound particles for injectable suspension 100mg and velcade bortezomib injection. (pharmatone.in)
- Bevacizumab (100mg/4ml) injection is an anticancer medicine that is used alone or in combination with other medicines for the treatment of various types of cancers such as colorectal cancer, glioblastoma multiforme, renal cell carcinoma, cervical cancer, ovarian cancer, etc. (pharmatone.in)
- We are a leading Manufacturer of calcitonin salmon nasal spray, orlistat 120 mg, relipoietin 4000iu injection, artesunate tab 100mg, vinlon 1mg injection and hertraz 440mg injection from Nagpur, India. (shrisanjivanmedicos.com)
Mercaptopurine1
- Patients with high-risk LCH must receive at least 1 year of combination therapy, such as a vincristine, prednisone, mercaptopurine combination. (medscape.com)
Peripheral neuropathy2
- One of the first symptoms of peripheral neuropathy is foot drop: A person with a family history of foot drop and/or Charcot-Marie-Tooth disease (CMT) should avoid vincristine. (wikipedia.org)
- With repeated doses of vincristine, you may feel symptoms of peripheral neuropathy (tingling sensation and numbness in the fingers and toes). (medicap.com)
Antineoplastic agent2
- Vincristine liposome is an antineoplastic agent (cancer medicine). (mayoclinic.org)
- Irinotecan hydrochloride injection is an antineoplastic agent of the topoisomerase I inhibitor class. (com.bd)
Vinlon 1mg Injection2
- Vinlon 1mg Injection is an anti-most cancers remedy used withinside the remedy of breast most cancers, non-small mobileular lung most cancers, pancreatic most cancers, kidney most cancers, blood most cancers, a couple of myeloma, lymphomas and bone most cancers. (jindalmedicalstore.in)
- Vinlon 1mg Injection is sold in bulk at very affordable prices. (jindalmedicalstore.in)
Cancer7
- Vincristine is used alone or in combination with other antineoplastic medications to treat many different types of cancer , including leukemia (cancer of white blood cells), lymphoma (cancer of the lymph cells), breast cancer, lung cancer, malignant melanoma, cancer of the cervix, colorectal cancer, and Wilms' tumor. (medbroadcast.com)
- As well as interfering with the genetic material DNA of cancer cells, vincristine can interfere with some of your normal cells. (medbroadcast.com)
- A downside, however, to Vincristine is that it does not only affect the division of cancer cells. (wikipedia.org)
- Vincristine interferes with the growth of cancer cells, which are eventually destroyed. (drugs.com)
- Cizumab 100 mg/4ml Injection is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian cancer and cervical cancer. (pharmatone.in)
- Vincristine treats certain types of cancer. (medicap.com)
- Vincristine has been use in combination with other medicines to treat certain types of cancer. (medicap.com)
Treatments2
- [ 12 ] In contrast, multiple bone lesions, alone or in association with a nonrisk site, may, although nonfatal, require 1 year of therapy with combination treatments such as prednisone plus vincristine. (medscape.com)
- Use a reliable method of birth control while receiving vincristine treatments. (medicap.com)
Tubulin1
- Vincristine works partly by binding to the tubulin protein, stopping the tubulin dimers from polymerizing to form microtubules, causing the cell to be unable to separate its chromosomes during the metaphase. (wikipedia.org)
Constipation1
- Your doctor may tell you to take a stool softener or laxative to help prevent constipation during your treatment with vincristine lipid complex. (medlineplus.gov)
Nausea3
- ZOFRAN Injection is indicated for the prevention of postoperative nausea and/or vomiting. (globalrph.com)
- In patients in whom nausea and/or vomiting must be avoided postoperatively, ZOFRAN Injection is recommended even when the incidence of postoperative nausea and/or vomiting is low. (globalrph.com)
- For patients who do not receive prophylactic ZOFRAN Injection and experience nausea and/or vomiting postoperatively, ZOFRAN Injection may be given to prevent further episodes [see Clinical Studies ]. (globalrph.com)
Bleomycin1
- Manufacturer of a wide range of products which include gemcitabine 200 mg injection, mitomycin c injection, bleomycin injection, cisplatin injection ip 50mg/50ml, bortezomin for injection 3.5mg and methotrexate injection injection usp 50mg/2ml. (aarjeyhealthcare.net)
Cyclophosphamide1
- Cyclotox(Cyclophosphamide for injection) is a sterile white powder containing cyclophosphamide monohydrate. (com.bd)
Interfere1
- you should know that vincristine may interfere with the normal menstrual cycle (period) in women and may temporarily or permanently stop sperm production in men. (medlineplus.gov)
Patients3
- We searched PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL) and three Chinese databases from inception to 20 July 2020 to identify randomized clinical trials (RCTs) that assessed the effects of Danhong injection as an add-on therapy in patients with ischemic stroke. (researchsquare.com)
- The addition of Danhong injection to western medicine may improve neurological function, self-care ability and blood lipids of ischemic stroke patients. (researchsquare.com)
- Vincristine is unique among the chemotherapeutic agents that it produces predictably and uniformly neurotoxicity in all the patients even at the therapeutic doses [ 6 ]. (biomedcentral.com)
Dextrose Injection1
- The preferred diluent is 5% Dextrose Injection, USP. (com.bd)
Tablets1
- The manufacturing of Tablets, Capsules, Liquid, and Lyophilized injections are all carried out at our world-class facility which is WHO-GMP and US FDA certified. (pharmika.co.in)
Medications1
- Vincristine lipid complex is in a class of medications called vinca alkaloids. (medlineplus.gov)
Interactions1
- This is not a complete list of vincristine drug interactions. (medicap.com)
Rats1
- The present study was designed to investigate the ameliorative potential of Ocimum sanctum and its saponin rich fraction in vincristine-induced peripheral neuropathic pain in rats. (biomedcentral.com)
Water for Injection2
- mannitol 100 mg and Water for Injection q.s. (medbroadcast.com)
- and 1.2 mg of methylparaben, NF and 0.15 mg of propylparaben, NF as preservatives in Water for Injection, USP. (globalrph.com)
Drug3
- The overuse of vincristine may also lead to drug resistance by overexpression of the p-glycoprotein pump (Pgp). (wikipedia.org)
- The liposome encapsulation of vincristine enhances the efficacy of the vincristine drug while simultaneously decreasing the neurotoxicity associated with it. (wikipedia.org)
- Local injection of hyaluronidase and the application of moderate heat to the area of leakage help disperse the drug and are thought to minimize discomfort and the possibility of cellulitis. (drugs.com)
Treatment3
- It is important for you to tell your doctor how you are feeling during your treatment with vincristine lipid complex. (medlineplus.gov)
- Most people experience some side effects from vincristine treatment. (wikipedia.org)
- Before you begin treatment with vincristine, you and your doctor should talk about the good this medicine will do as well as the risks of using it. (drugs.com)
Accidental1
- Accidental injection of vinca alkaloids into the spinal canal (intrathecal administration) is highly dangerous, with a mortality rate approaching 100 percent. (wikipedia.org)
Side effects1
- Vincristine lipid complex may cause side effects. (medlineplus.gov)