DiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesHealth Care
TopotecanInjectionsTopoisomerase I InhibitorsAntineoplastic AgentsCamptothecinDrug Administration ScheduleInjections, IntravenousDNA Topoisomerases, Type IOvarian NeoplasmsInfusions, IntravenousInjections, IntramuscularTopoisomerase InhibitorsInjections, IntralesionalAntineoplastic Combined Chemotherapy ProtocolsInjections, SubcutaneousDose-Response Relationship, DrugInjections, Intra-ArticularInjections, IntraperitonealCarcinoma, Small CellNeutropeniaArea Under CurveAdministration, OralLung NeoplasmsThrombocytopeniaRetinal NeoplasmsAcridinesRhabdomyosarcomaCisplatinDrug Resistance, NeoplasmAntineoplastic Agents, PhytogenicPaclitaxelATP-Binding Cassette TransportersNeoplasmsNeoplasm Recurrence, LocalAdministration, MetronomicInjections, IntradermalInjections, SpinalInjections, EpiduralInjections, IntraventricularSmall Cell Lung CarcinomaMaximum Tolerated DoseTreatment Outcome
HycamtinChemotherapyHydrochlorideInhibitorsSmall Cell LPaclitaxelBelongs to the groupChemotherapeutic agentsDrugsVialTopoisomeraseMetastatic cancerRetinoblastomaAllergicDose and dosing sCisplatinXenograftsAppointment to receiveInfusionMelphalanVinorelbineToxicityHypersensitivitySeverePowder for injectionOvarianTreatmentTreatmentsCOSELAReactionsMedicationsHarmPregnantAvastinCountsPatientsDrugCancer cellsSideType
Hycamtin8
  • HYCAMTIN (topotecan) for injection, for intravenous use is supplied as a sterile, lyophilized, buffered, light yellow to greenish powder available in single-dose vials. (globalrph.com)
  • HYCAMTIN® for injection, as a single agent, is indicated for the treatment of patients with metastatic ovarian cancer after disease progression on or after initial or subsequent chemotherapy. (globalrph.com)
  • HYCAMTIN for injection, as a single agent, is indicated for the treatment of patients with small cell lung cancer (SCLC) with platinum-sensitive disease who progressed at least 60 days after initiation of first-line chemotherapy. (globalrph.com)
  • HYCAMTIN for injection, in combination with cisplatin, is indicated for the treatment of patients with Stage IV-B, recurrent, or persistent cervical cancer not amenable to curative treatment. (globalrph.com)
  • The recommended dosage of HYCAMTIN for injection is 1.5 mg/m² by intravenous infusion over 30 minutes daily for 5 consecutive days, starting on Day 1 of a 21-day cycle until disease progression or unacceptable toxicity. (globalrph.com)
  • The recommended dosage of HYCAMTIN for injection is 0.75 mg/m² by intravenous infusion over 30 minutes daily on Days 1, 2, and 3, in combination with cisplatin 50 mg/m² on Day 1, of a 21-day cycle. (globalrph.com)
  • Do not administer subsequent cycles of HYCAMTIN for injection until neutrophils recover to greater than 1,000/mm³, platelets recover to greater than 100,000/mm³, and hemoglobin levels recover to greater than or equal to 9 g/dL (with transfusion if necessary). (globalrph.com)
  • For HYCAMTIN for injection as a single agent, reduce the dose to 0.75 mg/m²/day for patients with creatinine clearance (CLcr) of 20 to 39 mL/min (calculated with the Cockcroft-Gault method using ideal body weight) [see CLINICAL PHARMACOLOGY ]. (globalrph.com)
Chemotherapy10
  • Topotecan injection should be given only in a hospital or clinic under the supervision of a doctor with experience in the use of chemotherapy medications for cancer. (medlineplus.gov)
  • Aims To report outcomes with selective intra-arterial chemotherapy (SIAC) using simultaneous carboplatin, topotecan, and melphalan for advanced intraocular retinoblastoma. (bmj.com)
  • Aprifast IV Injection is a prescription medicine used to prevent nausea and vomiting caused by chemotherapy. (prakashbiopharma.org)
  • Phase I dose escalation study of vinorelbine and topotecan combination chemotherapy in patients with recurrent lung cancer. (musc.edu)
  • For instance, in February 2021, G1 Therapeutics, Inc., a commercial-stage oncology company, announced that the U.S. Food and Drug Administration (FDA) has approved COSELA (trilaciclib) for injection to reduce the incidence of chemotherapy-induced myelosuppression in adult patients when given before a platinum/etoposide-containing regimen or topotecan-containing regimen for advanced-stage small cell lung cancer (ES-SCLC). (coherentmarketinsights.com)
  • Cosela is a kinase inhibitor used to mitigate the incidence of chemotherapy-induced myelosuppression in adult patients when administered prior to a platinum/etoposide-containing regimen or topotecan-containing regimen for extensive-stage small cell lung cancer. (indianpharmanetwork.in)
  • GTHX ), a commercial-stage oncology company, today announced that the U.S. Food and Drug Administration (FDA) has approved COSELA™ (trilaciclib) for injection to decrease the incidence of chemotherapy-induced myelosuppression in adult patients when administered prior to a platinum/etoposide-containing regimen or topotecan-containing regimen for extensive-stage small cell lung cancer (ES-SCLC). (g1therapeutics.com)
  • Most people receive chemotherapy drugs through an injection or infusion. (medicalnewstoday.com)
  • This cancer chemotherapy drug is given by infusion into a vein or injection. (biogenindia.in)
  • We are API supplier in China of Topotecan Hcl, pharmaceutical raw material used for the treatment of relapsed small cell lung cancer in patients with a prior complete or partial response and who are at least 45 days from the end of first-line chemotherapy .Send us enquiry for Topotecan Hcl price if you have interest to buy it online. (inopha.net)
Hydrochloride2
  • Each 4 mg vial contains 4 mg topotecan hydrochloride as free base. (globalrph.com)
  • Our product range includes a wide range of clomifene citrate tablets ip, bethanechol chloride tablets, ondansetron orally disintegrating tablets, raloxifene hydrochloride tablets ip, levonorgestrel tablets ip and topotecan injection ip. (nbgmedexport.com)
Inhibitors1
  • Topotecan is in a class of medications called topoisomerase type I inhibitors. (medlineplus.gov)
Small Cell L1
  • Topotecan injection is used to treat ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed) and small cell lung cancer (a type of cancer that begins in the lungs) that have spread and did not improve after treatment with other medications. (medlineplus.gov)
Paclitaxel12
  • Paclitaxel injection IP (30 mg Z-Taxel Injection) is prescribed for the treatment of different types of cancer. (biogenindia.in)
  • A drug called intravenous paclitaxel injection (I.P.) is used to treat a number of cancers, including breast cancer, ovarian cancer, lung cancer, and others. (biogenindia.in)
  • Active component: The primary active component of Paclitaxel Injection I.P. is paclitaxel, a chemotherapeutic agent with a taxane basis. (biogenindia.in)
  • Different formulations: Paclitaxel Injection I.P. is offered in a range of formulations and strengths, allowing medical professionals to customize the dosage to meet the needs of each patient. (biogenindia.in)
  • 1. What is Paclitaxel Injection I.P? (biogenindia.in)
  • Paclitaxel Injection I.P is a medication used to treat various types of cancer, including breast, ovarian, and lung cancer. (biogenindia.in)
  • 2. How is Paclitaxel Injection I.P administered? (biogenindia.in)
  • Paclitaxel Injection I.P is administered through a vein by a healthcare professional in a clinical setting, such as a hospital or infusion center. (biogenindia.in)
  • 3. What are the common side effects of Paclitaxel Injection I.P? (biogenindia.in)
  • Common side effects of Paclitaxel Injection I.P may include hair loss, nausea, vomiting, diarrhea, mouth sores, muscle or joint pain, numbness or tingling in the hands or feet, and changes in taste. (biogenindia.in)
  • 4. Are there any serious side effects of Paclitaxel Injection I.P? (biogenindia.in)
  • Avastin in combination with paclitaxel and cisplatin or paclitaxel and topotecan is indicated for the treatment of persistent, recurrent, or metastatic carcinoma of the cervix. (runyoncanyon-losangeles.com)
Belongs to the group1
  • Topotecan belongs to the group of medicines called antineoplastics. (mayoclinic.org)
Chemotherapeutic agents3
  • These studies include the use of CED-delivery of NanoLiposomes carrying chemotherapeutic agents directly to brain tumor, including drugs such as irinotecan and topotecan. (wikipedia.org)
  • From this preliminary study, it appears that combination of dimer oxime and topotecan may be used as chemotherapeutic agents against nonsmall cell lung cancer. (wjtcm.net)
  • Administer topotecan under the supervision of a health care provider experienced in the use of cancer chemotherapeutic agents. (medicscientist.com)
Drugs2
  • Using these models, we attempted treatment of xenografts with topotecan - a known anticancer drug and artemisinin dimer oxime or combination of these two drugs. (wjtcm.net)
  • Three Effective Drugs With Wide Variation In Prices Avastin was priced at approximately $50 and Lucentis was priced at $1,950 per injection. (runyoncanyon-losangeles.com)
Vial2
  • Each single dose vial of solution contains topotecan HCL equivalent to 4 mg of topotecan as free base in 4 mL of Sterile Water for Injection USP. (pharmachoice.com)
  • Reconstitute each vial of powder with 4 mL of Sterile Water for Injection, for a final concentration of 1 mg/mL. (medicscientist.com)
Topoisomerase1
Metastatic cancer2
  • Topotecan is used to treat metastatic cancer of the ovary after other treatment(s) have failed. (pharmachoice.com)
  • Topotecan injection is used to treat patients with metastatic cancer (a cancer that has already spread) of the ovaries after other treatments have failed. (mayoclinic.org)
Retinoblastoma1
  • Topotecan and carboplatin were chosen for a three-drug combination with melphalan because they have been used successfully as single agents to treat both intraocular and metastatic retinoblastoma. (bmj.com)
Allergic1
  • tell your doctor and pharmacist if you are allergic to topotecan injection, any other medications, or any of the ingredients in topotecan injection. (medlineplus.gov)
Dose and dosing s1
  • The recommended dose and dosing schedule of topotecan varies according to body size and the results of blood tests carried out before your treatment. (pharmachoice.com)
Cisplatin1
Xenografts1
  • Novel ABCG2 Antagonists Reverse Topotecan-Mediated Chemotherapeutic Resistance in Ovarian Carcinoma Xenografts. (musc.edu)
Appointment to receive2
  • Call your doctor right away if you are unable to keep an appointment to receive a dose of topotecan injection. (medlineplus.gov)
  • If you miss an appointment to receive topotecan, contact your doctor as soon as possible to reschedule your appointment. (pharmachoice.com)
Infusion2
  • Protect vials from light in the original cartons at controlled room temperature 20° to 25°C (68° to 77°F). Reconstituted vials of topotecan diluted for infusion are stable at approximately 20° to 25°C (68° to 77°F) and ambient lighting conditions for 24 hr. (medicscientist.com)
  • Assess patients for signs/symptoms of injection-site reactions, phlebitis, and thrombophlebitis, including infusion-site pain and erythema during infusion. (indianpharmanetwork.in)
Melphalan3
  • Methods A retrospective chart review was conducted of patients who received three-drug (melphalan, topotecan, and carboplatin) SIAC during 2006-2011. (bmj.com)
  • In the three-drug therapy, dose ranges were 2.5-7.5 mg for melphalan, 0.3-0.6 mg for topotecan, and 25-50 mg for carboplatin, and median infusions per eye was 2 (range 1-4). (bmj.com)
  • Intravitreal melphalan injections can result in decreased ERG response, which is indicative of retinal toxicity (5,6) . (aboonline.org.br)
Vinorelbine1
  • Member of Farmavita.net is offering dossier in European CTD format for Vinorelbine, 10 mg/ml as 10 - 50 mg solution, solution for injection. (farmavita.net)
Toxicity2
Hypersensitivity1
  • Administration of Trilacicilib 300 mg injection can cause acute drug hypersensitivity reactions, including facial edema and urticaria. (indianpharmanetwork.in)
Severe1
  • Azithromycin may also be given by injection to treat severe pneumonia or pelvic inflammatory disease. (medbroadcast.com)
Powder for injection1
  • Member of Farmavita.net is offering dossier in European CTD format for Zeledronic acid, 4 mg, lyophilized powder for injection. (farmavita.net)
Ovarian3
  • When topotecan injection is used to treat ovarian or lung cancer, it is usually given once a day for 5 days in a row every 21 days. (medlineplus.gov)
  • In May 2021, On Target Laboratories, Inc. declared results of the 006 Study, a Phase 3, randomized, multi-center, prospective, open-label study to study the safety and efficacy of pafolacianine sodium injection (OTL38) for intraoperative imaging of folate receptor-positive ovarian cancer. (delhi-today.com)
  • Long-term survival advantage for the sake of women treated with pegylated liposomal doxorubicin compared with topotecan in a facet 3 randomized swat of recur- rental and refractory epithelial ovarian cancer. (daubnet.com)
Treatment5
  • We performed a phase 2 study in children with recurrent or refractory leptomeningeal leukemia to determine the objective response rate after treatment with intrathecal (IT) topotecan. (nih.gov)
  • Some effects may occur after treatment with topotecan has been stopped. (mayoclinic.org)
  • Injection is used in the treatment of early as well as metastatic breast cancer. (prakashbiopharma.org)
  • The implanted cells were allowed to grow for 10 days before initiation of drug treatment (dimer oxime and topotecan, ip). (wjtcm.net)
  • If filgrastim is used, do not initiate until day 6 of the course of therapy, 24 hr after completion of treatment with topotecan. (medicscientist.com)
Treatments1
  • Treatments with combination of topotecan and dimer oxime resulted in the reduced mortality rates in comparison with untreated mice. (wjtcm.net)
COSELA5
  • The interval between doses of Cosela Injection on sequential days should not be greater than 28 hours. (indianpharmanetwork.in)
  • Based on its mechanism of action, Cosela 300 mg injection can cause fetal harm if administered to a pregnant woman. (indianpharmanetwork.in)
  • COSELA (trilacicilib) injection can be imported by patients or government hospitals on the name of the patients only. (indianpharmanetwork.in)
  • COSELA (trilacicilib injection) is a (prescription drug, prescription medication or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed. (indianpharmanetwork.in)
  • Toll-Free No: 1800-889-1064 or write us at [email protected] for Cosela injection price in India. (indianpharmanetwork.in)
Reactions1
  • Administration of Trilacicilib can be responsible for causing injection-site reactions including phlebitis and thrombophlebitis. (indianpharmanetwork.in)
Medications2
  • Topotecan often causes nausea and vomiting, but you will be given medications to help control this. (pharmachoice.com)
  • Trastuzumab injection products are also used with other medications to treat certain types of stomach cancer that have spread to other parts of the body. (prakashbiopharma.org)
Harm1
Pregnant2
Avastin1
Counts1
Patients1
  • Cyclophosphamide and topotecan as first-line salvage therapy in patients with relapsed ewing sarcoma at a single institution. (musc.edu)
Drug1
  • Image-guided thermosensitive liposomes for focused ultrasound drug delivery: Using NIRF-labelled lipids and topotecan to visualise the effects of hyperthermia in tumours. (lido-dtp.ac.uk)
Cancer cells1
  • As well as interfering with the genetic material DNA of cancer cells, topotecan can interfere with some of your normal cells. (pharmachoice.com)
Side1
Type1
  • Topotecan injection may cause a decrease in the number of white blood cells (a type of blood cell that is needed to fight infection). (medlineplus.gov)