Cell ProliferationCalcium CarbonateCell DivisionCells, CulturedSignal TransductionCell Line, TumorApoptosisCell DifferentiationCell CycleCaco-2 CellsBromodeoxyuridineRNA, MessengerCell LineCell MovementCell SurvivalLymphocyte ActivationImmunohistochemistryBlotting, WesternTumor Cells, CulturedMice, Inbred C57BLProliferating Cell Nuclear AntigenReverse Transcriptase Polymerase Chain ReactionKi-67 AntigenPhosphorylationGene Expression Regulation, NeoplasticEpithelial CellsGene Expression RegulationRNA, Small InterferingCell Growth ProcessesDown-RegulationFlow CytometryT-LymphocytesMice, KnockoutTransfectionStem CellsDose-Response Relationship, DrugTime FactorsGene ExpressionCyclin D1Mice, TransgenicMolecular Sequence DataFibroblastsThymidineUp-RegulationMice, NudeMuscle, Smooth, VascularTranscription FactorsCell CountProto-Oncogene Proteins c-aktRNA InterferenceCyclin-Dependent Kinase Inhibitor p27Mice, Inbred BALB CCell Transformation, NeoplasticColonic NeoplasmsHyperplasiaIntestinal MucosaBase SequenceEnzyme ActivationMyocytes, Smooth MuscleDNAMitogensCell Cycle ProteinsEnzyme InhibitorsExtracellular Signal-Regulated MAP KinasesGrowth InhibitorsRats, Sprague-DawleyDNA-Binding ProteinsProto-Oncogene ProteinsProto-Oncogene Proteins c-mycCyclin-Dependent Kinase Inhibitor p21Gene Knockdown TechniquesGene Expression Regulation, DevelopmentalAntineoplastic AgentsPhenotypeProtein-Serine-Threonine KinasesMAP Kinase Signaling SystemInterleukin-2Disease Models, AnimalMitogen-Activated Protein Kinase 3G1 PhaseBreast NeoplasmsCell AdhesionModels, BiologicalMutationPlatelet-Derived Growth FactorGrowth SubstancesFibroblast Growth Factor 2Transforming Growth Factor betaMitogen-Activated Protein Kinase 1Recombinant ProteinsPhosphatidylinositol 3-KinasesNuclear ProteinsAmino Acid SequenceTranscription, GeneticNeovascularization, PathologicMitogen-Activated Protein KinasesEpitheliumTumor Suppressor Protein p53Gene Expression ProfilingTumor Suppressor Proteins