Inhibits human protein serine threonine kinases. Medical search. Frequent questions

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Anatomy18

Cell Line Cells, Cultured Tumor Cells, Cultured 3T3 Cells HeLa Cells Cell Nucleus COS Cells Cell Line, Tumor Cell Membrane HEK293 Cells Cytoplasm Jurkat Cells NIH 3T3 Cells Fibroblasts Subcellular Fractions Cytosol Cell Line, Transformed CHO Cells

Organisms8

Saccharomyces cerevisiae Cercopithecus aethiops Mice, Knockout Mice, Inbred C57BL Cattle Escherichia coli Cricetinae Drosophila

Diseases2

Peutz-Jeghers Syndrome Cell Transformation, Neoplastic

Chemicals and Drugs147

Protein-Serine-Threonine Kinases Phosphoprotein Phosphatases Threonine Protein Phosphatase 2 Protein Kinases Casein Kinase II Serine Calcium-Calmodulin-Dependent Protein Kinases Protein Phosphatase 1 Okadaic Acid Recombinant Proteins Oxazoles Ethers, Cyclic Protein Kinase C Enzyme Inhibitors Proto-Oncogene Proteins c-pim-1 DNA, Complementary Phosphatidylinositol 3-Kinases Phosphoproteins Phosphothreonine p21-Activated Kinases Phosphoserine Protein-Tyrosine Kinases Protein Kinase Inhibitors Proto-Oncogene Proteins Proto-Oncogene Proteins c-akt Glycogen Synthase Kinase 3 RNA, Messenger Death-Associated Protein Kinases MAP Kinase Kinase Kinases Proto-Oncogene Proteins c-raf Aurora Kinases Recombinant Fusion Proteins Tyrosine Activin Receptors Cyclic AMP-Dependent Protein Kinases Aurora Kinase A Proteins src-Family Kinases Receptors, Transforming Growth Factor beta Threonine Dehydratase Ribosomal Protein S6 Kinases Mitogen-Activated Protein Kinase Kinases Isoenzymes Intracellular Signaling Peptides and Proteins Serine Endopeptidases Mitogen-Activated Protein Kinase 1 p38 Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinases Aurora Kinase C JNK Mitogen-Activated Protein Kinases CDC2 Protein Kinase Microcystins Cell Cycle Proteins rho-Associated Kinases Cyclin-Dependent Kinase 5 DNA-Binding Proteins Carrier Proteins Mitogen-Activated Protein Kinase 3 Cyclin-Dependent Kinases Casein Kinases DNA Primers TOR Serine-Threonine Kinases Nuclear Proteins Adaptor Proteins, Signal Transducing MAP Kinase Kinase 1 Activin Receptors, Type I 3-Phosphoinositide-Dependent Protein Kinases Receptors, Growth Factor Staurosporine Receptor Protein-Tyrosine Kinases eIF-2 Kinase Protein Kinase C-alpha Transcription Factors Ribosomal Protein S6 Kinases, 90-kDa Phosphotyrosine Extracellular Signal-Regulated MAP Kinases Lim Kinases RNA, Small Interfering MAP Kinase Kinase 4 Protein Kinase C-delta Transforming Growth Factor beta Serine Proteinase Inhibitors Tetradecanoylphorbol Acetate Membrane Proteins DNA Phosphopeptides Serine Proteases Trans-Activators Phosphotransferases (Alcohol Group Acceptor)1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Glutathione Transferase Drosophila Proteins Androstadienes Peptides Saccharomyces cerevisiae Proteins I-kappa B Kinase Phosphoamino Acids Protein Kinase C beta AMP-Activated Protein Kinases Protein Isoforms Ribosomal Protein S6 Kinases, 70-kDa Chromones Multiprotein Complexes Protein Kinase C-epsilon Oncogene Proteins v-raf Amino Acids Creatine Kinase Indoles 14-3-3 Proteins Glycogen Synthase Kinases Morpholines Protein C Bone Morphogenetic Protein Receptors, Type I Adenosine Triphosphate Aurora Kinase B Pyruvate Kinase Calcium Smad2 Protein Bacterial Proteins Calcium-Calmodulin-Dependent Protein Kinase Type 2 MAP Kinase Kinase Kinase 1 Bone Morphogenetic Protein Receptors Actins Insulin Fungal Proteins Apoptosis Regulatory Proteins NF-kappa B Sirolimus Epidermal Growth Factor Oncogene Protein v-akt CDC2-CDC28 Kinases Phosphoric Monoester Hydrolases raf Kinases Receptors, Cell Surface Smad Proteins Thymidine Kinase Pyridines Maleimides Tumor Suppressor Proteins Proteome Nerve Tissue Proteins Phorbol Esters Isoquinolines MAP Kinase Kinase Kinase 5 Casein Kinase Ialpha Oncogene Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment21

Cloning, Molecular Transfection Mutagenesis, Site-Directed Sequence Alignment Blotting, Western Precipitin Tests Immunoprecipitation Two-Hybrid System Techniques Peptide Mapping Models, Biological Immunoblotting Protein Interaction Mapping Models, Molecular Electrophoresis, Polyacrylamide Gel Amino Acid Substitution Blotting, Northern Reverse Transcriptase Polymerase Chain Reaction Polymerase Chain Reaction Microscopy, Fluorescence Crystallography, X-Ray Mass Spectrometry

Phenomena and Processes54

Phosphorylation Amino Acid Sequence Base Sequence Substrate Specificity Sequence Homology, Amino Acid Signal Transduction Enzyme Activation Protein Binding Catalytic Domain MAP Kinase Signaling System Transfection Gene Expression Mutation Binding Sites Down-Regulation Protein Structure, Tertiary Kinetics Apoptosis Gene Expression Regulation, Enzymologic Catalysis Transcription, Genetic Protein Processing, Post-Translational Cell Division Cell Cycle Gene Expression Regulation Conserved Sequence Amino Acid Motifs Protein Transport Cell Survival Mitosis Time Factors Structure-Activity Relationship RNA Interference Cell Proliferation Amino Acid Substitution Plasmids Protein Conformation Dose-Response Relationship, Drug Promoter Regions, Genetic Phenotype Sequence Deletion Molecular Weight Gene Library Mutagenesis Cell Differentiation Gene Deletion Transcriptional Activation src Homology Domains Tissue Distribution Cell Movement Protein Interaction Domains and Motifs Point Mutation Up-Regulation Consensus Sequence

Disciplines and Occupations1

Information Science4

Molecular Sequence Data Amino Acid Sequence Base Sequence Databases, Protein

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science

Protein-Serine-Threonine Kinases Phosphoprotein Phosphatases Phosphorylation Molecular Sequence Data Amino Acid Sequence Threonine Protein Phosphatase 2 Protein Kinases Casein Kinase II Serine Calcium-Calmodulin-Dependent Protein Kinases Protein Phosphatase 1 Okadaic Acid Cloning, Molecular Base Sequence Substrate Specificity Recombinant Proteins Sequence Homology, Amino Acid Signal Transduction Oxazoles Enzyme Activation Ethers, Cyclic Cell Line Protein Kinase C Enzyme Inhibitors Proto-Oncogene Proteins c-pim-1 Protein Binding DNA, Complementary Phosphatidylinositol 3-Kinases Phosphoproteins Phosphothreonine p21-Activated Kinases Catalytic Domain Phosphoserine Protein-Tyrosine Kinases Protein Kinase Inhibitors Proto-Oncogene Proteins Proto-Oncogene Proteins c-akt MAP Kinase Signaling System Glycogen Synthase Kinase 3 Cells, Cultured RNA, Messenger Transfection Tumor Cells, Cultured Gene Expression Mutation Binding Sites Down-Regulation Death-Associated Protein Kinases Protein Structure, Tertiary Saccharomyces cerevisiae MAP Kinase Kinase Kinases Proto-Oncogene Proteins c-raf Aurora Kinases Recombinant Fusion Proteins Tyrosine Mutagenesis, Site-Directed Activin Receptors Cyclic AMP-Dependent Protein Kinases Aurora Kinase A Proteins src-Family Kinases Kinetics Receptors, Transforming Growth Factor beta Sequence Alignment Threonine Dehydratase Ribosomal Protein S6 Kinases Mitogen-Activated Protein Kinase Kinases Isoenzymes Intracellular Signaling Peptides and Proteins 3T3 Cells HeLa Cells Serine Endopeptidases Blotting, Western Mitogen-Activated Protein Kinase 1 Cell Nucleus p38 Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinases Apoptosis Precipitin Tests COS Cells Aurora Kinase C JNK Mitogen-Activated Protein Kinases CDC2 Protein Kinase Microcystins Cell Cycle Proteins rho-Associated Kinases Immunoprecipitation Cyclin-Dependent Kinase 5 DNA-Binding Proteins Carrier Proteins Mitogen-Activated Protein Kinase 3 Cyclin-Dependent Kinases Two-Hybrid System Techniques Casein Kinases Gene Expression Regulation, Enzymologic Cell Line, Tumor DNA Primers Catalysis Transcription, Genetic

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