• Nonsteroidal anti-inflammatory drugs (NSAIDs) are used in patients with Bartter syndrome. (medscape.com)
  • Relafen (nabumetone) is a nonsteroidal anti-inflammatory ( NSAID ) drug used to treat inflammation and pain caused by arthritis . (rxlist.com)
  • Nonsteroidal anti-inflammatory drugs (including Relafen) may rarely increase the risk for a heart attack or stroke . (rxlist.com)
  • Currently, the pharmacological approach of joint pain management is use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen, naproxen, and acetaminophen [ 6 ]. (medsci.org)
  • Among them, the nonsteroidal anti-inflammatory drugs (NSAIDs) are probably the most studied medications, showing effective outcomes in controllingperiodontal breakdown in pre-clinical experiments when systemically administered 3-5 . (bvsalud.org)
  • Likewise, dexamethasone can reduce cerebral cell apoptosis and inhibit inflammation [ 10 ,] and deferoxamine (DFX) provides new therapy target [ 11 ]. (karger.com)
  • Increasingly found in new skin care products, hemp seed oil helps moderate oil production and soothes skin inflammation thanks to its gamma-linolenic acid (GLA) inflammatory support. (naturalproductsinsider.com)
  • Broad Spectrum CBD is known to inhibit inflammation and contains powerful antioxidants. (dslaboratories.com)
  • Inflammation is thought to be a precursor to the development of cancer, and ginger's effectiveness as an anti-inflammatory agent is well-documented. (gayot.com)
  • In 2013, Li published findings that showed inflammation could be relieved by inhibiting the molecule PDE4B (phosphodiesterase 4B). (gra.org)
  • Psoriatic arthritis is a chronic autoimmune disease characterized by a form of inflammation of the skin ( psoriasis ) and joints (inflammatory arthritis ). (medicinenet.com)
  • Mesalamine is an anti-inflammatory agent, stopping the body from producing substances that cause inflammation. (hospitalninojesus.com)
  • This inhibits the production of prostaglandins, thereby reducing the inflammation in the rectum or the colon. (hospitalninojesus.com)
  • These agents are the most commonly used medications to control mild to moderate pain and to decrease inflammation. (medscape.com)
  • Blood proteomics reflected activation of inflammation-inhibiting pathways. (cdc.gov)
  • This anti-inflammatory property has turned aspirin into a potential drug for inflammation-related cancers such as colorectal cancer (CRC). (lu.se)
  • Our findings thus suggest that exposure to GWI-related agents may converge on similar targets with roles in inflammation, neurotransmitter and lipid metabolism, and detoxification which may have impacts on neurodegenerative-like disease and oxidative stress in Veterans with GWI. (cdc.gov)
  • Chronic inflammation, such as inflammatory bowel diseases (IBD), increases the risk of cancer. (lu.se)
  • Indomethacin inhibits prostaglandin synthesis. (medscape.com)
  • This drug inhibits inflammatory reactions and pain, probably by decreasing the activity of the enzyme cyclooxygenase, which results in decreased prostaglandin synthesis. (medscape.com)
  • This agent acts by inhibiting inflammatory reactions and pain via decreasing the activity of cyclooxygenase, which results in a decrease of prostaglandin synthesis. (medscape.com)
  • Azathioprine antagonizes purine metabolism and inhibits the synthesis of DNA, RNA, and proteins. (medscape.com)
  • Peripherally, aspirin acts by inhibiting the synthesis and release of prostaglandins. (pediatriconcall.com)
  • Itraconazole can inhibit CYP3A, thus interfering with synthesis of gluco- and mineralocorticoids, androgens and oestradiol as well as the metabolism of budesonide. (ersjournals.com)
  • Anti-inflammatory activities of the extracts of this plant were previously attributed to inhibition of cyclooxygenase-2 mRNA and prostaglandin E 2 synthesis. (aspetjournals.org)
  • Mercaptopurine is a purine analog that inhibits DNA and RNA synthesis, causing cell proliferation to arrest. (medscape.com)
  • Methotrexate is an antimetabolite that inhibits DNA synthesis and cell reproduction in malignant cells. (medscape.com)
  • The enzyme deoxycytidine kinase phosphorylates this compound into active 5+-triphosphate derivative, which, in turn, breaks DNA strands and inhibits DNA synthesis. (medscape.com)
  • EGFR-ERK signaling act downstream of berberine/pro-inflammatory cytokines axis to regulate CACRC cell proliferation. (nih.gov)
  • They suppress the release of cytokines and other inflammatory signals, and inhibit the production of reactive oxygen species. (wikipedia.org)
  • Botanical polyphenolic constituents are effective inhibitors of pro-inflammatory enzymes, thus prevent formation of toxic cytokines generated through inflammatory reactions [ 2 ]. (medsci.org)
  • IL-1 alpha and IL-1 beta are potent pro-inflammatory cytokines that induce a wide variety of biological activities on different cell types. (rndsystems.com)
  • NSIADs have analgesic, anti-inflammatory, and antipyretic activities. (medscape.com)
  • Carprofen is a non-narcotic, non-steroidal anti-inflammatory agent with characteristic analgesic and antipyretic activity approximately equipotent to indomethacin in animal models. (drugs.com)
  • Aspirin (acetylsalicylic acid) an analgesic, antipyretic, and anti-inflammatory agent. (pediatriconcall.com)
  • Studies have demonstrated that, in the form of alcoholic extracts, decoctions, and infusions, C. verbenacea exhibits important anti-rheumatic, anti-inflammatory, analgesic, and healing properties which are related to a protective effect on the gastric mucosa, as well as very low toxicity when orally or topically administered 12-17 . (bvsalud.org)
  • Member has had an inadequate response, intolerance, or contraindication to non-steroidal anti-inflammatory drugs (NSAIDs), colchicine and corticosteroids. (aetna.com)
  • Similarly, the steroidal anti-inflammatory drug, dexamethasone (0.3-3 mg kg -1 , i.p.), completely inhibited the oedema produced dose-dependently. (scialert.net)
  • Here, we show that in primary human femoral head osteoarthritic and normal bovine chondrocytes, TWHF partially or completely inhibited mRNA and protein expression of tumor necrosis factor-α, interleukin (IL)-1, and IL-17-inducible MMP-3 and MMP-13. (aspetjournals.org)
  • The major pharmacologic action of agents in this class is noncompetitive inhibition of the enzyme carbonic anhydrase. (medscape.com)
  • It inhibits PDE4 to the greatest extent, but also shows significant inhibition of other PDE subtypes, and so acts as a selective PDE4 inhibitor or a non-selective phosphodiesterase inhibitor, depending on the dose. (wikipedia.org)
  • Inhibition of COX-1 is thought to be associated with gastrointestinal and renal toxicity while inhibition of COX-2 provides anti-inflammatory activity. (drugs.com)
  • Carprofen has also been shown to inhibit the release of several prostaglandins in two inflammatory cell systems: rat polymorphonuclear leukocytes (PMN) and human rheumatoid synovial cells, indicating inhibition of acute (PMN system) and chronic (synovial cell system) inflammatory reactions. (drugs.com)
  • The pathogenesis is most likely an itraconazole caused increase in systemic budesonide concentration through a reduced/inhibited metabolism leading to inhibition of adrenocorticotrophic hormone secretion along with a direct inhibition of steroidogenesis. (ersjournals.com)
  • Melatonin as a natural body hormone is a potent antioxidant and anti-inflammatory agent that shows some anti-cancer properties. (unboundmedicine.com)
  • These additional chemical agents have also been shown to inhibit AChE. (cdc.gov)
  • Xie C, Kang J, Li Z, Schauss AG , Badger TM, Nagarajan S, Wu T, Wu X. The açaí flavonoid velutin is a potent anti-inflammatory agent: blockade of LPS-mediated TNF-α and IL-6 production through inhibiting NF-κB activation and MAPK pathway. (aibmr.com)
  • Sildenafil, tadalafil, vardenafil, and the newer udenafil and avanafil selectively inhibit PDE5, which is cGMP-specific and responsible for the degradation of cGMP in the corpus cavernosum. (wikipedia.org)
  • We have previously shown that helenalin and other sesquiterpene lactones selectively inhibit activation of the transcription factor NF-kappaB, a central mediator of the human immune response. (greenmedinfo.com)
  • However, whether the anti-inflammatory effect of berberine contributes to its anti-tumor effect on colitis-associated colorectal cancer (CACRC) remains unknown. (nih.gov)
  • The potential for selective phosphodiesterase inhibitors as therapeutic agents was predicted as early as 1977 by Weiss and Hait. (wikipedia.org)
  • PDE4 inhibitors have proven potential as anti-inflammatory drugs, especially in inflammatory pulmonary diseases such as asthma, COPD, and rhinitis. (wikipedia.org)
  • Aggarwal then covers curcumin's role in several aspects of health, such as serving as an anti-inflammatory agent (inhibiting NF-KB, COX-2, STAT3 and TNF-a), an immune system modulator (inhibiting adhesion molecules and cytokine expression), an antioxidant, an anti-cancer agent and more. (wholefoodsmagazine.com)
  • The anti-inflammatory and anti-tumor effects of berberine, a traditional Chinese medicine, were separately discovered in pathological intestinal tissues. (nih.gov)
  • Altogether, the results of our studies have revealed that berberine inhibits the development of CACRC by interfering with inflammatory response-driven EGFR signaling in tumor cell growth. (nih.gov)
  • Selenium, a tumor-inhibiting element is also found in bok choy. (mifb.com.my)
  • Fortunately, in contrast to classic antioxidants, some in vitro studies have revealed that melatonin has a potent anti-tumor activity when used alongside irradiation. (unboundmedicine.com)
  • Patients receiving anti-tumor necrosis factor-α (anti-TNF-α) therapy are at increased risk for tuberculosis and other granulomatous diseases, but little is known about illness caused by nontuberculous mycobacteria (NTM) in this setting. (cdc.gov)
  • To date, TB and NTM infections and concurrent biologic therapies that inhibit tumor necrosis factor-α (TNF-α) have been reported. (cdc.gov)
  • 2010. Xanthohumol and related prenylated flavonoids inhibit inflammatory cytokine production in LPS-activated THP-1 monocytes: structure-activity relationships and in silico binding to myeloid differentiation protein-2 (MD-2). . (oregonstate.edu)
  • Staphylococcus aureus), its acetophenones, phloroglucinols and terpenoids displayed antifungal action against Candida albicans and its flavonoids and phloroglucinols inhibited HSV and HIV, respectively. (oil-testimonials.com)
  • the anti-inflammatory properties exhibited by its flavonoids, acetophenones and phloroglucinols, as seen in animal models. (oil-testimonials.com)
  • These potent effects are driven by curcumin's ability to induce G2/M cell cycle arrest, induce autophagy, activate apoptosis, disrupt molecular signaling, inhibit invasion and metastasis, and increase the efficacy of current chemotherapeutics. (hindawi.com)
  • TruProfen Flavored Tab is a non-steroidal anti-inflammatory drug (NSAID) of the propionic acid class that includes ibuprofen, naproxen, and ketoprofen. (drugs.com)
  • Minor) Zafirlukast inhibits the CYP2C9 isoenzymes and should be used cautiously should be used cautiously in patients stabilized on drugs metabolized by CYP2C9, such as ibuprofen. (pdr.net)
  • These drugs must target a central step in NF-kappaB pathway, since they inhibit NF-kappaB induction by four different stimuli. (greenmedinfo.com)
  • The different forms or subtypes of phosphodiesterase were initially isolated from rat brains in the early 1970s and were soon afterward shown to be selectively inhibited in the brain and in other tissues by a variety of drugs. (wikipedia.org)
  • PDE3 is sometimes referred to as cGMP-inhibited phosphodiesterase. (wikipedia.org)
  • In summary, C. erythrocarpos has anti-inflammatory and antipyretic activity and these findings support the use of the extract in traditional medicine for treating inflammatory conditions. (scialert.net)
  • The potential anti-neuroinflammatory effects of propranolol were interrogated by analysis of cytokine mRNA expression. (cdc.gov)
  • Propranolol treatment abrogated the elaboration of inflammatory cytokine mRNA expression in the brain instigated in our model, having no treatment effects in non-DFP exposed groups. (cdc.gov)
  • Triptolide inhibits the inflammatory response of monocytes from rheumatoid arthritis patients by regulating miR-155]. (curehunter.com)
  • To explore the anti-inflammatory effect of triptolide ( TPT ) by regulating miR-155 in monocytes pre-stimulated by lipopolysaccharide (LPS) from rheumatoid arthritis (RA) patients. (curehunter.com)
  • These products work by blocking TNF-α, an inflammatory cytokine, and are approved for treating rheumatoid arthritis and other selected autoimmune diseases. (cdc.gov)
  • Assessment of the epidemiology of these infections may be increasingly useful because newer forms of biologic, immunosuppressive therapies have become widely used for treating patients with rheumatoid arthritis, Crohn disease, and other autoimmune inflammatory conditions. (cdc.gov)
  • Abbott Biotechnology, Abbott Park, IL, USA), which have been approved in the United States and elsewhere to treat patients with rheumatoid arthritis and selected other autoimmune inflammatory diseases ( 4 ). (cdc.gov)
  • PURPOSE: Available evidence indicates that dipyridamole enhances the anti-thrombotic effects of aspirin for the prevention of secondary strokes. (lu.se)
  • Aspirin is a well-known non-steroid anti-inflammatory drug. (lu.se)
  • Here, we aimed to explore whether the anti-cancer effect of aspirin against CRC could be improved by combined administration with dipyridamole. (lu.se)
  • METHODS: Population-based clinical data analysis was conducted to assess a possible therapeutic effect of combined dipyridamole and aspirin treatment in inhibiting CRC compared with either monotherapy. (lu.se)
  • The enhanced anti-cancer effect of the combined use of dipyridamole with aspirin was found to rely on the induction of an overwhelmed endoplasmic reticulum (ER) stress and subsequent pro-apoptotic unfolded protein response (UPR), which was different from the anti-platelet effect. (lu.se)
  • CONCLUSIONS: Our data indicate that the anti-cancer effect of aspirin against CRC may be enhanced by combined administration with dipyridamole. (lu.se)
  • Resveratrol contains a compound that inhibits an oxidizing agent, has anti-inflammatory and antimicrobial properties and exerts stronger antioxidant effects than vitamin E and C. 1-4 ​ Studies show it can stop skin damage and improve skin firmness, elasticity and density. (cosmeticsdesign-europe.com)
  • In vitro studies characterized Helichrysum as an antimicrobial and anti-inflammatory agent. (oil-testimonials.com)
  • Since ginger inhibits the formation of inflammatory compounds, it can quell other inflammatory conditions such as asthma and migraines and is safer than pharmaceuticals. (gayot.com)
  • Intraplantar injection of carrageenan into the footpad of the 7-day-old chick has been found to elicit a measurable, reliable and relatively short lasting state of oedema that is differentially attenuated by systemic administration of typical anti-inflammatory compounds ( Roach and Sufka, 2003 ). (scialert.net)
  • The findings of this study support the possibility that berberine and other anti-inflammatory drugs may be beneficial in the treatment of CACRC. (nih.gov)
  • These include glucocorticoids and non-steroidal anti-inflammatory drugs. (lifeextension.com)
  • Drugs that inhibit IL-1 beta signaling may be helpful, too. (lifeextension.com)
  • Nitroxide small molecule agents are in development as preventative or therapeutic pharmaceutical drugs for age-related macular degeneration (AMD) and cardiovascular disease, which are two major diseases of aging. (frontiersin.org)
  • With Li's discovery comes the promise of new anti-inflammatory drugs, potentially to be manufactured by ROCK Pharmaceuticals, of which Li is a cofounder. (gra.org)
  • Budesonide is metabolised to 16‐α‐hydroxyprednisolone and 6‐β‐hydroxybudesonide by hepatic CYP3A 15 , and the metabolism is therefore reduced in individuals taking drugs that inhibit CYP3A. (ersjournals.com)
  • This way, the search for new drugs that effectively interfere with the immune-inflammatory process is currently important. (bvsalud.org)
  • At the end of the experimental duration, rats were sacrificed to perform biochemical and gene expression analyses related to lipid regulatory and inflammatory pathways. (bvsalud.org)
  • Development of novel therapeutic agents for inflammatory and infectious diseases. (gra.org)
  • Developing Vinpocetine into an anti-inflammatory therapeutic agent and developing novel therapeutic agents for inhibiting mucus overproduction and reducing lethality. (gra.org)
  • Pioneering studies suggest that the lipostatic, antiproliferative, and anti-inflammatory effects of CBD offer tremendous benefits for hair growth and stimulation. (dslaboratories.com)
  • Curcumin has extensive therapeutic potential because of its antioxidant, anti-inflammatory, and antiproliferative properties. (hindawi.com)
  • The aim of the study was to assess the activity of an ethanolic extract of Capparis erythrocarpos Isert roots in the carrageenan-induced foot oedema model in chicks, an acute inflammatory model and baker s yeast-induced pyrexia in rats. (scialert.net)
  • We speculate that our proposed mechanism of macrophage induced nitrosative stress contributes to effective clearance of apoptotic cells and regulates switching of acute inflammatory response to anti-inflammatory phase as has been observed in the lung and in the brain in in vivo experiments with inhalation of single-walled carbon nanotube s and cortical trauma, respectively. (cdc.gov)
  • [ 80 ] The role of biologic agents is being investigated. (medscape.com)
  • PDE4 is the major cAMP-metabolizing enzyme found in inflammatory and immune cells. (wikipedia.org)
  • However, treatment with Met inhibited the reduction of LPS-induced enzyme levels as well as the elevation of LC3b and ROS levels. (nature.com)
  • However, how inflammatory and anti-inflammatory environments affect macrophage mitochondrial function is poorly understood. (nature.com)
  • It has previously been reported that sesquiterpene lactones exert their effect by inhibiting degradation of IkappaB, the inhibitory subunit of NF-kappaB. (greenmedinfo.com)
  • 5-9 Data also indicate that Carprofen inhibits the production of osteoclast-activating factor (OAF), PGE 1 , and PGE 2 by its inhibitory effects on prostaglandin biosynthesis. (drugs.com)
  • Threshold limit values for chemical substances and physical agents. (cdc.gov)
  • Threshold limit values for chemical substances and physical agents and biological exposure indices. (cdc.gov)
  • Mesalamine is a medication known as an anti-inflammatory agent that is prescribed to treat a condition known as ulcerative colitis where there is sores and swelling in the rectum lining or the colon lining. (hospitalninojesus.com)
  • This agent also inhibited cytokine-stimulated MMP-3 protein expression in human synovial fibroblasts. (aspetjournals.org)
  • This study aims to explore the energy metabolism of macrophages under either inflammatory or anti-inflammatory conditions by adding LPS and Met, respectively, using an in vitro and an in vivo model. (nature.com)
  • To enhance the existing knowledge about the beneficial properties, this study investigates the antioxidant, antihyperlipidemic, and anti-inflammatory effects of black truffle extract in in vitro biochemical assays and animal study. (bvsalud.org)
  • Immunosuppressive agents are useful adjuvants in patients with pemphigus vulgaris with generalized disease unresponsive to steroids and/or other anti-inflammatory agents or in patients unable to tolerate prednisone. (medscape.com)
  • As a result, it lacks the anti-inflammatory and immunosuppressive properties that can cause adverse events such as cataract development and elevated intraocular pressure leading to glaucoma. (medscape.com)
  • This study therefore was to investigate the anti-inflammatory properties of the extract in carrageenan-induced foot oedema in chicks. (scialert.net)
  • These agents have anti-inflammatory properties and cause profound and varied metabolic effects. (medscape.com)
  • These results suggest that pirfenidone inhibits local arginase activity possibly through suppression of endogenous TGF-beta, hence, limiting the development of fibrosis in lung allografts. (nih.gov)
  • Therefore, besides its anti-inflammatory activity, this agent may also be effective in blocking cartilage matrix resorption by MMPs by impairing AP-1 and NF-κB binding activities. (aspetjournals.org)
  • Because protein S-nitrosylation can act as a regulatory redox-sensitive mechanism, we hypothesized that nitrosative stress enhances PS externalization in cells by inhibiting APT activity. (cdc.gov)
  • Taking into account the extensive presence of C. verbenacea in Brazilian folk medicine, and considering the anti-inflammatory activity previously reported 12-17 our group was prompted to assess the impact of C. verbenacea in modulating periodontal disease progression. (bvsalud.org)
  • The sesquiterpene lactone helenalin is a potent anti-inflammatory drug whose molecular mechanism of action remains unclear despite numerous investigations. (greenmedinfo.com)
  • Among the promising drug candidates the company would like to produce and market is Vinpocetine, used in Europe and Asia for decades as a treatment for memory loss, now being shown effective as an anti-inflammatory. (gra.org)
  • She started standard, four-drug anti-TB therapy but experienced gastrointestinal intolerance. (cdc.gov)
  • We reviewed the US Food and Drug Administration MedWatch database for reports of NTM disease in patients receiving anti-TNF-α therapy. (cdc.gov)
  • The drug functions instead as an angiostatic agent, inhibiting blood vessel growth by decreasing extracellular protease expression and inhibiting endothelial cell migration. (medscape.com)
  • The goal of the current study was to evaluate the potential for the -adrenergic receptor inhibitor and anti-inflammatory drug, propranolol, to treat neuroinflammation in a novel long-term mouse model of GWI. (cdc.gov)
  • For centuries, the Ayurvedic tradition in India and Tibet has made use of ginger to treat inflammatory joint diseases including arthritis and rheumatism. (gayot.com)
  • Those who have inflammatory arthritis and psoriasis are diagnosed as having psoriatic arthritis . (medicinenet.com)
  • The importance of infectious agents and other environmental factors in the cause of psoriatic arthritis is being investigated by researchers. (medicinenet.com)
  • Whole genome analysis of lung, sampled 24 hours after challenge, showed expression changes of not only genes belonging to several Gene Ontology groups with up-regulation of inflammatory-associated genes and those associated with lung remodeling but also genes involved in downsizing these processes. (cdc.gov)
  • TPT suppressed the expression of miR-155 and up-regulated the release of SHIP-1, thus inhibiting the inflammatory response in the LPS-stimulated monocytes of RA patients. (curehunter.com)
  • A Cornell University study found that ginger inhibits the aggregation of platelets, which can lead to blood clots. (gayot.com)
  • Brewed as a tea, ginger induces healthy sweating, which reduces fevers, detoxifies the body and transports an important germ-fighting agent - dermicidin - to the skin's surface. (gayot.com)
  • Although the etiological role of microorganisms in the pathogenesis of this disease is clear, the host's immune-inflammatory response can lead to protective and/or destructive effects on periodontal tissues 1 . (bvsalud.org)
  • Innumerous biological systems have been suggested as alternatives to modulate the host's immune-inflammatory response involved in periodontal disease 2 . (bvsalud.org)
  • The aim of treatment is to reduce the inflammatory response and autoantibody production. (medscape.com)
  • Anti-inflammatory agents may be helpful in the treatment of gout flares. (lifeextension.com)
  • Treatment with itraconazole, an orally administered triazole antifungal agent, has recently been recommended for the treatment of ABPA as an efficient alternative or steroid-sparing therapy without serious side-effects 8 - 10 . (ersjournals.com)
  • Pretreatment for 30 min or 1 h (but not 2-10 h) after IL-1 treatment with TWHF inhibited MMP-3 RNA induction. (aspetjournals.org)
  • Clobetasol is a very potent topical corticosteroid indicated for adults, elderly and children over 1 year for the short term treatment only of more resistant inflammatory and pruritic manifestations of steroid responsive dermatoses unresponsive to less potent corticosteroids. (medicines.org.uk)
  • In conclusion, the mitochondrial TCA cycle is affected by the inflammatory environment, and the LPS-induced effects can be reversed by Met treatment. (nature.com)
  • They might be exploited as a possible food supplement or even as a natural source of pharmaceutical agents for diabetes prevention and treatment. (bvsalud.org)
  • Prescription therapies are often used to support healthy uric acid levels, a healthy inflammatory response and patient comfort. (lifeextension.com)
  • Quinapril inhibits the elevation in blood pressure caused by intravenously administered angiotensin I, but has no effect on the pressor response to angiotensin II, norepinephrine, or epinephrine. (nih.gov)
  • Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. (rndsystems.com)
  • This study aimed to explore the mitochondrial response under inflammatory and anti-inflammatory environments, with a focus on the tricarboxylic acid (TCA) cycle. (nature.com)
  • TamaFlex TM (NXT15906F6) is a synergistic anti-inflammatory formulation which contains ethanol/aqueous extracts of Tamarindus indica seeds and ethanol extract of Curcuma longa rhizome. (medsci.org)
  • B cells may be acting at multiple sites in the autoimmune/inflammatory process, including T-cell activation and/or proinflammatory cytokine production. (medscape.com)
  • Anti-inflammatory agents inhibit the inflammatory process by inhibiting specific cytokine production. (medscape.com)
  • A tree fruit extract has been studied for its ability to safely inhibit uric acid production without the use of side effect-prone medications. (lifeextension.com)
  • Children are more likely to develop local and systemic side effects of topical corticosteroids and, in general, require shorter courses and less potent agents than adults. (medicines.org.uk)
  • In addition, melatonin has shown the ability to inhibit long-term changes in inflammatory responses at different levels, thereby ameliorating late side effects of radiotherapy. (unboundmedicine.com)
  • Inhibiting or preventing the actions of muscarine and muscarinelike agents, or the effects of parasympathetic stimulation at the neuroeffector junction ( e.g., atropine). (theodora.com)
  • Overall, our results suggested that black truffle possesses strong antihyperlipidemic and anti-inflammatory effects on diabetic rats. (bvsalud.org)
  • No cytotoxic effects were induced by either of the trans-nitrosating agents. (cdc.gov)
  • Such inflammatory tissue damage is responsible for morbidity and mortality in patients. (ersjournals.com)
  • In the present study, we found that berberine effectively inhibited colitis-associated tumorigenesis and colonic epithelium hyperproliferation in dextran sulfate sodium (DSS)-treated Apc Min/+ mice. (nih.gov)
  • The anti-inflammatory sesquiterpene lactone helenalin found in Arnica inhibits the transcription factor NF-kappaB by directly targeting p65. (greenmedinfo.com)
  • Patent co-inventor Nibaldo Inestrosa stated, 'We found that Andrographolide activates Wnt signaling and inhibits GSK-3b. (nutraceuticalsworld.com)
  • G. anti + monos, not found alone] a. chloride SYN: a. trichloride. (theodora.com)
  • 2002). considered to be an inflammatory disorder. (cdc.gov)
  • Pirfenidone is an investigational anti-fibrotic agent shown to be effective in blocking pulmonary fibrosis. (nih.gov)
  • In case further clinical studies confirm our findings, these may be repurposed as adjuvant agents. (lu.se)