• He continued treatment with growth hormone and an aromatase inhibitor was added to delay growth plate fusion and to potentially increase his final adult height. (juniperpublishers.com)
  • The only obviousdifference that is seen in all men with Klinefelter syndrome is clearly visible difference in testicular size between men with Klinefelter syndrome (verysmall testes) and men with 46,XY karyotype (normal size). (health-abstracts.com)
  • description is not accurate and men with Klinefelter syndrome represent a broad spectrum of phenotypes, professions, incomes and socioeconomic status The 47,XXY karyotype of Klinefelter syndrome arises Severe intellectual deficits are rare. (health-abstracts.com)
  • Patients with mosaic 45, X/46,X(r)Y karyotype, present with phenotypes ranging from females with Turner-like phenotypes, phenotypic males and females with mixed gonadal dysgenesis, to almost phenotypic normal males [ 4 , 5 ]. (juniperpublishers.com)
  • Testicular biopsy is indicated in azoospermic men with a normal-sized testis and normal findings on hormonal studies to evaluate for ductal obstruction, to further evaluate idiopathic infertility, and to retrieve sperm. (medscape.com)
  • Infertility in men can result from deficiencies in sperm formation, concentration, or transportation. (medscape.com)
  • Indications for performing a postcoital test include semen hyperviscosity, increased or decreased semen volume with good sperm density, or unexplained infertility. (medscape.com)
  • Causes of infertility in men can be categorized as obstructive or nonobstructive. (medscape.com)
  • The initial evaluation of the male patient should be rapid, noninvasive, and cost-effective, as nearly 70% of conditions that cause infertility in men can be diagnosed with history, physical examination, and hormonal and semen analysis alone. (medscape.com)
  • Men withKlinefelter syndrome present with sequels of hormonal and spermatogenic testicular Correspondence to Darius A. Paduch, MD, PhD,Department of Urology, Weill Medical College of failure like infertility, low testosterone, erectile dysfunction, and low bone mineral Cornell University, 525 East 68th Street F-924A, density. (health-abstracts.com)
  • Andrology, sexual dysfunction and infertility Figure 1 The classic descriptions of men with Klinefelter syndrome are based on the most severe cases of phenotypic abnormalities Most teenagers and young adults seen in our practice have typical body proportions, arm span and penile length as their peers. (health-abstracts.com)
  • Causes of infertility in men can be explained by deficiencies in sperm formation, concentration, or transportation. (medscape.com)
  • Panel Discussion Problems of MALE INFERTILITY & Management of Oligo Astheno T. (slideshare.net)
  • On presentation, he had a normal male phenotype, short stature, palpable testes and delayed sexual development. (juniperpublishers.com)
  • Although bicalutamide does not bind to the ERs, it can increase estrogen levels secondarily to blockade of the AR when used as a monotherapy in males, and for this reason, the medication can indirectly activate the ERs to a degree and hence have some indirect estrogenic effects in men. (wikipedia.org)
  • Development of randomized clinical trialscomparing different forms of interventions in men and children with Klinefelter syndromewill allow us to standardize the care of these patients. (health-abstracts.com)
  • However, over the last 10years, with advancements in artificial reproductive tech-niques and the successful delivery of healthy children from men with Klinefelter syndrome, the involvement of Klinefelter syndrome is the most common numerical urologists in the care of patients with Klinefelter syn- chromosomal aberration among men, with an estimated drome is increasingly important. (health-abstracts.com)
  • Although the classic description of men with Klinefelter Urologists are in a unique position to address long-term syndrome emphasized tall eunuchoid body proportions, care of patients with Klinefelter syndrome in respect to low testosterone, sparse facial and pubic hair, small hard their reproductive and sexual function. (health-abstracts.com)
  • Normal male ductal anatomy. (medscape.com)
  • Methods: FXR-/- male mice were randomly divided into three groups based on different interventions for 16 weeks, including normal diet (ND), high-fat diet (HFD), and probiotic intervention in the HFD (HFD+P) group. (bvsalud.org)
  • Here, we present the molecular cytogenetics of 45,X/46,X(r)Y mosaicism in a 12-year-old boy with normal male phenotype, chordee, short stature andpubertal delay. (juniperpublishers.com)
  • The initial step in the evaluation of an infertile male is to obtain a thorough medical and urologic history. (medscape.com)
  • IVF-ICSI is a type of ART used to overcome severe oligospermia or azoospermia by injecting a single sperm into the cytoplasm of a mature egg. (medscape.com)
  • Background: This study evaluated whether microsurgical varico-celectomy performed in infertile men with severe oligozoospermia (SO) resulted in improved semen parameters or increased rates of spontaneous pregnancy (SP) and performed a cost-effectiveness analysis comparing intrauterine insemination (IUI), in vitro fertilization (IVF), and varicocelectomy. (bvsalud.org)
  • An abnormal postcoital test result is observed in 10% of infertile couples. (medscape.com)
  • Sperm parameters, presence of varicocele, and testicular volume were evaluated in our patients. (bvsalud.org)
  • The predominance of azoospermia and oligospermia should prompt a search for a genetic predisposition in these subjects. (bvsalud.org)
  • These men present with no previous history of diseases affecting fertility and have normal findings on physical examination and endocrine, genetic and biochemical laboratory testing, although semen analysis may reveal pathological findings (see Section 11.3.2). (uroweb.org)
  • PATIENTS AND METHODS: We conducted a cross-sectional, descriptive, retrospective study of 100 infertile patients followed at the Histology-Embryology-Cytogenetics laboratory of UCAD in Dakar, during the year 2020. (bvsalud.org)
  • Infertile men may have deficiencies in sperm formation, concentration (eg, oligospermia [too few sperm], azoospermia [no sperm in the ejaculate]), or transportation. (medscape.com)
  • There are marked geographic differences in the prevalence of male reproductive disorders. (nih.gov)
  • An estimated 15% of couples meet this criterion and are considered infertile, with approximately 35% due to female factors alone, 30% due to male factors alone, 20% due to a combination of female and male factors, and 15% unexplained. (medscape.com)
  • For this reason, in all infertile couples the male should undergo medical evaluation by a urologist trained in male reproduction. (uroweb.org)
  • Male reproductive health and environmental xenoestrogens. (nih.gov)
  • Male reproductive health has deteriorated in many countries during the last few decades. (nih.gov)
  • Exposure of the male fetus to supranormal levels of estrogens, such as diethlylstilbestrol, can result in the above-mentioned reproductive defects. (nih.gov)
  • The growing number of reports demonstrating that common environmental contaminants and natural factors possess estrogenic activity presents the working hypothesis that the adverse trends in male reproductive health may be, at least in part, associated with exposure to estrogenic or other hormonally active (e.g., antiandrogenic) environmental chemicals during fetal and childhood development. (nih.gov)
  • Several drugs including dopamine antagonists, selective serotonin reuptake inhibitors, tricyclic antidepressants, and high-dose estrogen therapy cause hyperprolactinemia and should be discontinued if possible in this situation. (medscape.com)
  • Although bicalutamide does not bind to the ERs, it can increase estrogen levels secondarily to blockade of the AR when used as a monotherapy in males, and for this reason, the medication can indirectly activate the ERs to a degree and hence have some indirect estrogenic effects in men. (wikipedia.org)
  • [ 21 ] Men receiving GnRH therapy should be instructed by their health care professional to monitor the needle-insertion site daily and report any redness, pain, or drainage. (medscape.com)
  • Likewise, advanced maternal age must be considered in the management of every infertile couple, and in the subsequent decisions in the diagnostic and therapeutic strategy of the male partner [ 1762 , 1763 ]. (uroweb.org)
  • this is dangerous because approximately 6% of males evaluated have a serious underlying medical condition. (medscape.com)
  • The initial step in the evaluation of an infertile male is to obtain a thorough medical and urologic history. (medscape.com)
  • If sperm concentrations are unsatisfactory after 6 to 12 months of therapy, an FSH preparation should be added to hCG. (medscape.com)
  • Men with uncorrectable, untreatable, or unknown etiologies may benefit from ART. (medscape.com)