AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
CarcinomaCarcinoma, Squamous CellCarcinoma, HepatocellularCarcinoma in SituCarcinoma, PapillaryLiver NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Basal CellImmunohistochemistryCarcinoma, Transitional CellCarcinoma, BronchogenicCarcinoma, Intraductal, NoninfiltratingCarcinoma, Adenoid CysticCarcinoma, Small CellTumor Markers, BiologicalCarcinoma, MedullaryAdenocarcinomaCarcinoma, LobularCarcinoma, NeuroendocrineNeoplasm InvasivenessNasopharyngeal NeoplasmsCell Line, TumorPrognosisThyroid NeoplasmsBreast NeoplasmsNeoplasm StagingGene Expression Regulation, NeoplasticTumor Cells, CulturedLung NeoplasmsCarcinoma, MucoepidermoidCarcinoma, AdenosquamousCarcinoma, EndometrioidHead and Neck NeoplasmsCarcinoma, EmbryonalEsophageal NeoplasmsMouth NeoplasmsCarcinoma, Merkel CellCarcinoma, DuctalLymphatic MetastasisOvarian NeoplasmsAdrenocortical CarcinomaColonic NeoplasmsCarcinoma, VerrucousCarcinoma, Signet Ring CellNeoplasm MetastasisUrinary Bladder NeoplasmsStomach NeoplasmsNeoplasm ProteinsSkin NeoplasmsNeoplasm Recurrence, LocalMice, NudeCarcinoma, Large CellDNA, NeoplasmLaryngeal NeoplasmsAntineoplastic AgentsRetrospective StudiesUterine Cervical NeoplasmsImmunoenzyme TechniquesRNA, MessengerNeoplasm TransplantationNeoplasms, Multiple PrimarySurvival RateAdenocarcinoma, FollicularSurvival AnalysisAdenocarcinoma, MucinousTreatment OutcomeAntigens, NeoplasmEmbryonal Carcinoma Stem CellsReverse Transcriptase Polymerase Chain ReactionPrecancerous ConditionsCarcinoma, Papillary, FollicularGallbladder NeoplasmsCarcinoma, Non-Small-Cell LungTumor Suppressor Protein p53Endometrial NeoplasmsAdenocarcinoma, Clear CellDisease ProgressionColorectal NeoplasmsCell Proliferationalpha-FetoproteinsTongue NeoplasmsApoptosisPancreatic NeoplasmsCystadenocarcinoma, SerousCarcinoma, Lewis LungCombined Modality TherapyBronchial NeoplasmsCell DivisionSalivary Gland NeoplasmsTissue Array AnalysisDisease-Free SurvivalKeratinsCisplatinTime FactorsRNA, NeoplasmFollow-Up StudiesMutationCell Transformation, NeoplasticTransplantation, HeterologousBiopsy
SquamousMetastaticMucoepidermoid carcinomaHepatocellular carcinomaUrothelial CarcinomaTumorsEndocytosis inhibitionEndometrialTumorGastric CarcinomaUncommon neoplasmCutaneousSalivary glandsMalignancyPatientsPrimaryIncidenceInvasionNSCLCProgressionRadiotherapyDiagnosisAxisThyroidCancerPathwaysHeadBreastRadiationRoleCells
Squamous21
  • The present review scrutinize the existing documentation in the literature related to the oral squamous cell carcinoma. (ujds.in)
  • The present review spotlights on understanding the molecular mechanism and the genetic factors which is responsible for alteration in the cell which leads to oral squamous cell carcinoma. (ujds.in)
  • Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease. (ujds.in)
  • Excretory stem cells give rise to squamous cell and mucoepidermoid carcinomas, while intercalated stem cells give rise to pleomorphic adenomas, oncocytomas, adenoid cystic carcinomas, adenocarcinomas, and acinic cell carcinomas. (medscape.com)
  • Squamous cell carcinomas arise from excretory duct cells, pleomorphic adenomas arise from the intercalated duct cells, oncocytomas arise from the striated duct cells, and acinic cell carcinomas arise from acinar cells. (medscape.com)
  • After therapy, the incidence of pleomorphic adenomas, mucoepidermoid carcinomas, and squamous cell carcinomas is increased. (medscape.com)
  • Tobacco and alcohol, which are highly associated with head and neck squamous cell carcinoma, have not been shown to play a role in the development of malignancies of the salivary glands. (medscape.com)
  • Diagnostic performance of computed tomography features in detecting oropharyngeal squamous cell carcinoma extranodal extension. (dana-farber.org)
  • Inhibiting the inhibitors: Development of the IAP inhibitor xevinapant for the treatment of locally advanced squamous cell carcinoma of the head and neck. (dana-farber.org)
  • Unusual presentation of HPV-positive squamous cell carcinoma of the nasolacrimal duct as carcinoma of unknown primary. (dana-farber.org)
  • Adjuvant radiation following clear margin resection of high T-stage cutaneous squamous cell carcinoma halves the risk of local and locoregional recurrence: A dual-center retrospective study. (dana-farber.org)
  • However, its role in the development and metastasis of tongue squamous cell carcinoma (TSCC) remains unclear. (oncotarget.com)
  • The group has described the genomic landscape of head & neck squamous cell carcinoma, esophageal cancer and medullary thyroid cancer, and has developed assays using tumor DNA as a biomarker in saliva and plasma. (uchicago.edu)
  • Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features. (uchicago.edu)
  • Oral cavity and oropharyngeal squamous cell carcinoma genomics. (uchicago.edu)
  • Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas. (uchicago.edu)
  • Tadalafil augments tumor specific immunity in patients with head and neck squamous cell carcinoma. (uchicago.edu)
  • Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke. (uchicago.edu)
  • Disease-free survival after salvage therapy for recurrent oropharyngeal squamous cell carcinoma. (uchicago.edu)
  • The report shows squamous cell carcinoma on several biopsies. (pdfcoffee.com)
  • However, Notch signaling is inactivated in small‑cell lung cancer and squamous cell carcinomas. (spandidos-publications.com)
Metastatic3
  • BACKGROUND: Recurrent/metastatic adenoid cystic carcinoma (ACC) is a rare, incurable disease. (bvsalud.org)
  • Open-label Phase II study investigating the efficacy of Cetuximab and prochlorperazine (Stemetil) combination therapy in patients with metastatic Head and Neck Carcinoma (CESTEM II study). (edu.au)
  • Successful treatment of c-kit-positive metastatic Adenoid Cystic Carcinoma (ACC) with a combination of curcumin plus imatinib: A case report. (rsdjournal.org)
Mucoepidermoid carcinoma3
  • It is the third-most common malignant salivary gland tumor overall (after mucoepidermoid carcinoma and polymorphous adenocarcinoma). (wikipedia.org)
  • Mucoepidermoid carcinoma is the most common salivary gland malignancy in children. (medscape.com)
  • Accordingly, mucoepidermoid carcinoma (MEC) is the most frequent subtype, with more than 30% of the SGC cases, followed by the adenoid cystic carcinoma (ACC) with the pathology in 23.8% of all SGC cases, and the adenocarcinoma not otherwise specified [ 4 ]. (genominfo.org)
Hepatocellular carcinoma4
  • ET to discuss the Phase 3 study of rivoceranib in combination with camrelizumab in unresectable hepatocellular carcinoma (uHCC). (biotech-365.com)
  • Dr. Abou-Alfa is a medical oncologist at Memorial Sloan Kettering Cancer Center, specializing in the treatment and management of gastrointestinal malignancies, with a particular focus on liver cancer (hepatocellular carcinoma) and biliary tract cancers (cholangiocarcinoma). (biotech-365.com)
  • Locoregional therapy is playing an increasingly important role in the non-surgical management of hepatocellular carcinoma (HCC). (xiahepublishing.com)
  • With the benefit of the tumor being treated locally, it has played an increasingly important role in the non-surgical management of hepatocellular carcinoma (HCC). (xiahepublishing.com)
Urothelial Carcinoma2
  • This is an open label Phase 1b/2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or in combination with ultralow dose gemcitabine in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSignature® test status. (uci.edu)
  • This phase II trial studies how well Ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor AZD6738 works alone or in combination with olaparib or durvalumab in treating participants with renal cell carcinoma (RCC), urothelial carcinoma, all pancreatic cancers, endometrial cancer, and other solid tumors excluding clear cell ovarian cancer that have spread to nearby tissue or lymph nodes or other parts of the body. (ucbraid.org)
Tumors2
  • Relative incidence of parotid tumors, with adenoid cystic carcinoma being relatively rare. (wikipedia.org)
  • Where there are no alternative treatment options, NCCN recommends immune checkpoint inhibition for patients with these TMB-high tumors. (genomeweb.com)
Endocytosis inhibition1
  • The ins and outs of endocytosis inhibition: providing diverse opportunities for treatment of incurable cancers. (edu.au)
Endometrial1
  • Further validation of the testing approach comes from NCCN: TMB analysis using an FDA-approved test is recommended ahead of second-line treatment decisions for cervical cancer , uterine sarcoma and endometrial carcinoma , vulvar cancer , bone cancer , and cancer of unknown primary . (genomeweb.com)
Tumor6
  • citation needed] Coronal MRI showing right parotid adenoid cystic carcinoma with perineural spread of tumor: The tumor originates in the right parotid gland and spreads along the trigeminal nerve via the auricuotemporal branch extending intracranially through the foramen ovale at the skull base towards Meckel's cave. (wikipedia.org)
  • Carcinoma-associated fibroblasts (CAF) are the most important cells in tumor microenvironment. (researchsquare.com)
  • The authors hypothesized that AKT inhibition with the allosteric inhibitor MK-2206 could decrease MYB expression and induce tumor regression in patients with incurable ACC (ClinicalTrials.gov identifier NCT01604772). (bvsalud.org)
  • Formerly considered to be a "one-size-fits-all" approach, immune checkpoint inhibition via the PD-1/PD-L1 axis has since demonstrated improved response rates in patients with a high TMB across ten solid tumor types: response rates were 29 percent and 6 percent in patients with a high TMB and a low TMB across different cancer types, respectively. (genomeweb.com)
  • VEGFR-2 inhibition is a clinically validated approach to limit tumor growth and disease progression. (biotech-365.com)
  • Many carcinomas display perineural invasion (PNI) a tropism of tumor cells for surrounding nerve bundles. (tam-receptor.com)
Gastric Carcinoma1
  • it is mutated in about 46% of ovarian clear cell carcinoma (OCCC), 33% of gastric carcinoma, 27% of cholangiocarcinoma and 15% of pancreatic carcinoma [see, NPL 1-4], all of which lack effective molecular targeting therapies. (justia.com)
Uncommon neoplasm2
  • Pulmonary adenoid cystic carcinoma (PACC) is an uncommon neoplasm of the lung but represents the predominant type of salivary gland-type lung carcinoma. (biomedcentral.com)
  • Salivary gland carcinoma (SGC) is an uncommon neoplasm, which constitutes approximately 6 percent of cancers in the head and neck region [ 1 , 2 ]. (genominfo.org)
Cutaneous1
  • Primary cutaneous adenoid cystic carcinoma Collagenous spherulosis Marchiò C, Weigelt B, Reis-Filho JS (Mar 2010). (wikipedia.org)
Salivary glands1
  • It is presumed to originate from the minor salivary glands lining the tracheobronchial tree and is one of the main types of salivary gland-type carcinoma of the lung [ 1 ]. (biomedcentral.com)
Malignancy1
  • Risk of second primary malignancy after nasopharyngeal carcinoma in the United States: A population-based study. (uchicago.edu)
Patients2
  • AKT inhibition may diminish MYB protein levels, although the effect was highly variable among patients. (bvsalud.org)
  • The relationship between chronic lymphocytic thyroiditis and central neck lymph node metastasis in North American patients with papillary thyroid carcinoma. (uchicago.edu)
Primary3
  • The data presented in this work suggest that EGFR, KRAS, BRAF, ALK, PIK3CA, PDGFRA, and DDR2 may not be driver genes in primary pulmonary adenoid cystic carcinoma. (biomedcentral.com)
  • Primary pulmonary adenoid cystic carcinoma (PACC) is a rare neoplasm. (biomedcentral.com)
  • Inhibition to tracheal surgery before 1960 was explained by difficulties related to perioperative ventilation, the poor healing capacity of cartilage and, finally, the "2-cm Belsey rule" stipulating that it was not possible to remove more than 2 cm of the trachea with primary reconstruction [ 1 ]. (biomedcentral.com)
Incidence1
  • Effect of Arginase-1 Inhibition on the Incidence of Autoimmune Diabetes in NOD Mice. (juniperpublishers.com)
Invasion1
  • miR-597-3p could reduce the proliferation, invasion and migration abilities of SW579 cells, which may be related to the targeted inhibition of RAB23 expression and down-regulation of the expression levels of MMP-2, MMP-9 and N-cadherin proteins of SW579 cells. (viamedica.pl)
NSCLC1
  • The present study explored the expression and potential role of TRIM13 in non-small-cell lung carcinoma (NSCLC). (cancerindex.org)
Progression1
  • Carcinoma-associated fibroblasts (CAF) play a pivotal role in cancer progression. (researchsquare.com)
Radiotherapy1
  • Characterization of clinical outcomes after shorter course hypofractionated and standard-course radiotherapy for stage I-III curatively-treated Merkel cell carcinoma. (dana-farber.org)
Diagnosis1
Axis2
  • EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer. (cornell.edu)
  • Newly Identified Members of FGFR1 Splice Variants Engage in Cross-talk with AXL/AKT Axis in Salivary Adenoid Cystic Carcinoma. (cornell.edu)
Thyroid1
  • questions on the mechanism and drugs involved in thyroid hormone formation and inhibition. (pdfcoffee.com)
Cancer3
  • Adenoid cystic carcinoma is a rare type of cancer that can exist in many different body sites. (wikipedia.org)
  • Salivary gland carcinoma (SGC) is rare cancer, constituting 6% of neoplasms in the head and neck area. (genominfo.org)
  • ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer. (cornell.edu)
Pathways1
  • Studies show that curcumin has a significant response in the anti-inflammatory action, acting especially in the inhibition of multiple pro-inflammatory pathways, decreasing the activities of the cytokines of this process. (rsdjournal.org)
Head1
  • Therapeutic targets and immune therapy for head and neck adenoid cystic carcinoma. (edu.au)
Breast1
Radiation2
  • Treatments for adenoid cystic carcinoma of the busts: Is postoperative the radiation acquiring their due credit? (pdgfrsignals.com)
  • 12. 50-year-old man with T2N2M0O EBV + Nasopharynx carcinoma is treated with 70 Gy radiation with concurrent cisplatin and has complete resolution of disease. (examyear.com)
Role1
  • We believe that the plexins and semaphorins which are strongly expressed in both axons and many carcinomas play a role in PNI. (tam-receptor.com)
Cells2
  • TRIM13 inhibited cell proliferation and induced cell apoptosis by regulating NF-κB pathway in non-small-cell lung carcinoma cells. (cancerindex.org)
  • Herein we show that nerve cell lines migrate toward PC3 cells and exhibit extended nerve processes in a Sema4D/plexin-B1-dependent manner a response also blocked by Rho/ROK inhibition. (tam-receptor.com)