• vaccine
  • As a large animal model, the horse is also a useful species in which to evaluate the potential of new generations of influenza vaccine such as live-attenuated influenza virus engineered by reverse genetics. (blogspot.com)
  • Live attenuated influenza virus vaccine. (blogspot.com)
  • A more important clinical implication of this work is the identification of a universal neutralizing epitope in the HA stalk at the atomic level an important intellectual landmark for the development of a universal influenza vaccine. (wikipedia.org)
  • with vaccine production hoped to increase until one billion doses are produced by one year after the virus is first identified. (wikipedia.org)
  • The companies receiving the contracts were: GlaxoSmithKline $274.8 million MedImmune Inc $169.5 million Novartis Vaccines and Diagnostics $220.5 million DynPort Vaccine Company, LLC $41 million Solvay Pharmaceuticals $298.6 million The US government purchased from Sanofi Pasteur and Chiron Corporation several million doses of vaccine meant to be used in case of an influenza pandemic due to H5N1 and is conducting clinical trials on them[when? (wikipedia.org)
  • The vaccine is usually effective against three or four types of influenza. (wikipedia.org)
  • A vaccine made for one year may not be useful in the following year, since the virus evolves rapidly. (wikipedia.org)
  • HPAI
  • The global HPAI situation significantly improved in the first half of 2008, but the FAO reports that imperfect disease surveillance systems mean that occurrence of the virus remains underestimated and underreported. (wikipedia.org)
  • HPAI A(H5N1) is considered an avian disease, although there is some evidence of limited human-to-human transmission of the virus. (wikipedia.org)
  • Due to the high lethality and virulence of HPAI A(H5N1), its endemic presence, its increasingly large host reservoir, and its significant ongoing mutations, the H5N1 virus has recently been regarded to be the world's largest current pandemic threat, and billions of dollars are being spent researching H5N1 and preparing for a potential influenza pandemic. (wikipedia.org)
  • Between 1959 and 1995, there were 15 recorded occasions of the emergence of HPAI viruses in poultry, but losses were minimal. (wikipedia.org)
  • viral
  • Complications of influenza may include viral pneumonia, secondary bacterial pneumonia, sinus infections, and worsening of previous health problems such as asthma or heart failure. (wikipedia.org)
  • conjunctivitis
  • Of these 89 patients, 78 presented with conjunctivitis, 5 presented with conjunctivitis and influenza-like illness, 2 presented with influenza-like illness, and 4 did not fit the case definitions. (pnas.org)
  • Mild
  • Influenza-like illnesses were generally mild, but a fatal case of pneumonia in combination with acute respiratory distress syndrome occurred also. (pnas.org)
  • Type C viruses are less common and cause mild diseases in children. (mynewsdesk.com)
  • However, influenza C is less common than the other types and usually seems to cause mild disease in children. (wikipedia.org)
  • Pigs
  • McCauley, J. W. 1997-05-01 00:00:00 An H1N7 influenza A virus, isolated from pigs in England in 1992, was examined genetically to determine the characteristics and probable origin of the eight gene segments. (deepdyve.com)
  • The main hosts appear to be cattle but this virus has been reported from pigs also. (wikipedia.org)
  • mutate
  • however, this virus did not mutate to spread easily between people. (wikipedia.org)
  • Therefore, before considering FI6 as long-term prophylactic or therapeutic agent against seasonal influenza, we would first have to determine whether the influenza virus could quickly mutate the epitope targeted by FI6 and escape recognition by FI6 after exposure. (wikipedia.org)
  • illness
  • To better understand the epidemiology, geographic spread, and clinical spectrum of this virus in China, we describe the Chinese National Influenza-Like Illness Surveillance Network (CNISN) and analyze data collected since March 4, 2013. (cdc.gov)
  • deaths
  • Farmers Guardian reported a 2.5 per cent increased mortality in one shed and a reduction in egg production recorded two weeks before a large number of deaths on 2 June that led to the diagnosis of HP H7N7 on 4 June. (wikipedia.org)