MicrogliaInflammationSystemic Inflammatory Response SyndromeCytokinesMice, Inbred C57BLLipopolysaccharidesInflammation MediatorsCells, CulturedTumor Necrosis Factor-alphaMacrophagesDisease Models, AnimalAstrocytesMice, KnockoutInterleukin-6EncephalitisNF-kappa BInterleukin-1betaNeutrophilsBrainSignal TransductionAnti-Inflammatory AgentsGliosisAntigens, CD11bChemokinesToll-Like Receptor 4Interleukin-8Gene Expression RegulationLungRats, Sprague-DawleyRNA, MessengerImmunity, InnateNeurogliaNitric Oxide Synthase Type IIMice, TransgenicAnimals, NewbornImmunohistochemistryPhagocytosisTime FactorsNeutrophil InfiltrationToll-Like Receptor 2MonocytesSepsisNeuronsCell LineReverse Transcriptase Polymerase Chain ReactionUp-RegulationLeukocytesCentral Nervous SystemMacrophage ActivationChemokine CCL2MinocyclineInterleukin-1Enzyme-Linked Immunosorbent AssayMice, Inbred BALB CAmyloid beta-PeptidesPneumoniaNerve DegenerationInterleukin-10PeroxidaseGlial Fibrillary Acidic ProteinCell DeathCoculture TechniquesNitric OxideBronchoalveolar Lavage FluidInterferon-gammaToll-Like ReceptorsCyclooxygenase 2Cell MovementRats, Wistarp38 Mitogen-Activated Protein KinasesReactive Oxygen SpeciesApoptosisBlotting, WesternGene ExpressionMacrophages, PeritonealIntercellular Adhesion Molecule-1Cell CountSpinal CordChemotaxis, LeukocyteFlow CytometryDose-Response Relationship, DrugLeukocyte CountMyeloid Differentiation Factor 88Chemokine CXCL2Analysis of VarianceDermatitisBiological MarkersPrimary Cell CultureNeuroprotective AgentsAlzheimer DiseaseEndotoxinsOxidative StressEndotoxemiaReperfusion InjuryPhagocytesAcute-Phase ReactionReal-Time Polymerase Chain ReactionChemokine CX3CL1Cell SurvivalNeuroimmunomodulation