• Porphyromonas gingivalis Fusobacterium nucleatum is found between the early and late colonisers, linking them together. (wikipedia.org)
  • A deacidification rate 60% attenuated the bactericidal effect against planktonic and biofilm-embedded Aggregatibacter actinomycetemcomitans but had no impact on Porphyromonas gingivalis and Fusobacterium nucleatum. (cranberryinstitute.org)
  • Cranberry juice increased the adherence of A. actinomycetemcomitans and P. gingivalis to oral epithelial cells, but reduced the adherence of F. nucleatum by half regardless of the deacidification rate. (cranberryinstitute.org)
  • A model multi-species sub-gingival community containing Fusobacterium nucleatum, Streptococcus constellatus , Parvimonas micra with wild type or isogenic mutants of P. gingivalis was then created and growth and proteolytic activity in serum assessed as above. (biomedcentral.com)
  • Fusobacterium nucleatum is one bacteria species found commonly in the mouth, which is a key member of colorectal cancer-associated bacteria. (lumoral.com)
  • A. oris induces the coaggregation of the early colonizers Streptococcus gordonii and Streptococcus sanguinis with the intermediate colonizer Fusobacterium nucleatum in oral biofilms [ 1 ]. (biomedcentral.com)
  • Some bacteria can contribute to carcinogenesis by producing toxins (such as Helicobacter pylori cytotoxin), inducing chronic inflammation (such as Fusobacterium nucleatum in colorectal cancer) or altering DNA methylation (such as Streptococcus gallolyticus in colon cancer). (stemcelldaily.com)
  • Tannerella forsythia is an anaerobic, fusiform Gram-negative oral pathogen strongly associated with periodontitis, a multibacterial inflammatory disease that leads to the destruction of the teeth-supporting tissue, ultimately causing tooth loss. (karger.com)
  • Oral dysbiosis, which potentially causes periodontitis to subsequently promote systemic inflammation and local vascular inflammation, increases the risks of cardiovascular diseases (CVDs). (degruyter.com)
  • During oral dysbiosis and periodontitis, local inflammation in periodontal tissue and permeability of local capillaries are enhanced, therefore bacteria from oral microbiome and bacteria-released toxins can enter the systemic circulation. (degruyter.com)
  • Oral dysbiosis promotes periodontitis pathogenesis, enhancing chronic local inflammation in periodontal tissue, local production of pro-inflammatory cytokines and permeability of surrounding capillaries. (degruyter.com)
  • Periodontitis, a major oral disease, affects a vast majority of the population but has been often ignored without realizing its long-fetched effects on overall human health. (encyclopedia.pub)
  • Periodontitis is one of the most prevalent dysbiotic oral diseases and is known to affect at least one tooth in 80% of adults worldwide [ 1 ] . (encyclopedia.pub)
  • Attention to this link was perhaps first recognized in the late 1980s when a group of scientists published data suggesting apposite observations such as the existence of periodontitis in addition to cardiovascular diseases was present in pregnant females facing premature labors and deliveries, as they suffered from periodontitis during the pregnancy [ 4 ] . (encyclopedia.pub)
  • The inhibition of quorum sensing, called quorum quenching, may disrupt oral biofilm formation, which is the main etiological factor of oral diseases, including periodontitis. (mdpi.com)
  • Periodontitis is a chronic inflammatory disorder of infectious etiology involving the hard and soft periodontal tissues and which is related to various systemic disorders, including cardiovascular diseases, diabetes and obesity. (mdpi.com)
  • Periodontitis is a highly prevalent, chronic multifactorial infectious disease, induced by the dysbiotic biofilm that triggers a persistent systemic inflammation and recurrent bacteremia. (intechopen.com)
  • There is a growing body of scientific evidence that suggests the potential implication of periodontitis in the causation and progression of various systemic disease and conditions, such as diabetes, cardiovascular disease, pulmonary disease, adverse pregnancy outcomes and cancer. (intechopen.com)
  • Despite sparse scientific data, some studies indicate that individuals with periodontitis are at increased risk for cancer development, due to the increased inflammatory burden sustained by the presence of periodontal pathogens. (intechopen.com)
  • This chapter emphasis the relationship between periodontitis and adverse pregnancy outcomes and the underlying mechanisms that link peridontitis to oral carcinogenesis. (intechopen.com)
  • The pathogenic bacterial complex can lead to dental caries, periodontitis and gingivitis. (encyclopedia.pub)
  • In addition, dental biofilm, especially subgingival plaque in patients with periodontitis, has been associated with cardiovascular and respiratory disease and diabetes mellitus, and recently constituting a high risk for developing severe illness due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection [ 2 ] . (encyclopedia.pub)
  • Periodontal diseases include two main conditions: gingivitis and periodontitis. (encyclopedia.pub)
  • Periodontitis is a complex, chronic inflammatory disease caused by an abnormal host response to bacteria from dental plaque. (encyclopedia.pub)
  • Dysbiosis in subgingival microbial communities, resulting from increased inflammatory transudate from the gingival tissues, is an important factor in initiation and development of periodontitis. (biomedcentral.com)
  • This enzyme is called T reponema denticola chymotrypsin-like proteinase - or dentilisin - and it is usually found in the mouth, where it is known to contribute to severe gum disease (periodontitis). (lumoral.com)
  • The abundance of #Porphyromonadaceae and #Fusobacterium , which are co-pathogens in periodontitis and intestinal inflammation was significantly enriched in the gut of the C-SP group. (metabiom.org)
  • Although, the disease appears as a locoregional infection, the periodontal pathogens, in addition their metabolic products and systemic mediators, receive access to the bloodstream, thereby contributing to the development of systemic disorders. (encyclopedia.pub)
  • therefore, the current study was designed to assess the efficacy of certain antibiotics, toothpaste, and medicinal plant extracts ( Ajuga bracteosa and Curcuma longa ) versus the bacterial pathogens isolated from the human oral cavity. (scielo.br)
  • Among all the bacterial species, Staphylococcus aureus (29.62%) and Proteus mirabilis (22.2%) were found to be more prevalent oral pathogens. (scielo.br)
  • The data obtained through this study revealed that antibiotics were more effective for oral bacterial pathogens than toothpaste and plant extracts which showed moderate and low activity, respectively. (scielo.br)
  • Effect of cranberry juice deacidification on its antibacterial activity against periodontal pathogens and its anti-inflammatory properties in an oral epithelial cell model. (cranberryinstitute.org)
  • #Nisin and a #Nisin -producing Lactococcus lactis probiotic significantly decreased the levels of several periodontal pathogens, alveolar bone loss, and the oral and systemic inflammatory host response. (metabiom.org)
  • Do Oral Pathogens Inhabit the Eye and Play a Role in Ocular Diseases? (metabiom.org)
  • However, many other oral pathogens can play a role in the development of cancer as well. (lumoral.com)
  • The normal flora also competes with potential pathogens for nutrients and attachment sites, produces antimicrobial substances (such as bacteriocins and hydrogen peroxide) and modulates inflammatory responses. (stemcelldaily.com)
  • Dysbiosis can result in reduced diversity and functionality of the normal flora, increased susceptibility to pathogens or opportunistic infections (such as Clostridium difficile colitis or oral candidiasis), altered immune responses or metabolic disorders (such as obesity or diabetes). (stemcelldaily.com)
  • #Streptococcus salivarius K12 and M18 prevented immune activation induced by periodontal disease pathogens. (metabiom.org)
  • Some members of the genera #Porphyromonas , #Prevotella , and #Tannerella are well-known pathogens of the oral cavity, where they can notably cause periodontal disease and dental #Caries . (metabiom.org)
  • This is due to the unique virulence factor s produced by individual pathogens, which determine the extent and severity of disease they may cause. (pressbooks.pub)
  • To survive in the oral habitat, T. forsythia depends on cohabiting bacteria for the provision of nutrients. (karger.com)
  • This report summarizes T. forsythia 's strategies to survive in the oral habitat by means of PGN salvage pathways, including recovery of exogenous MurNAc and PGN-derived fragments but also polymeric PGN, which are all derived from cohabiting bacteria either via cell wall turnover or decay of cells. (karger.com)
  • Dental plaque is a biofilm of microorganisms (mostly bacteria, but also fungi) that grows on surfaces within the mouth. (wikipedia.org)
  • Bacteria then attach to the pellicle layer, form micro-colonies, and mature on the tooth, which can result in oral diseases. (wikipedia.org)
  • The following table provides a more detailed (six-step) explanation of biofilm formation: Different types of bacteria are normally present in the mouth. (wikipedia.org)
  • These bacteria, as well as leukocytes, neutrophils, macrophages, and lymphocytes, are part of the normal oral cavity and contribute to the individual's health. (wikipedia.org)
  • Below is a summary of the bacteria that may be present during the phases of plaque maturation: Early biofilm: primarily Gram-positive cocci Older biofilm (3-4 days): increased numbers of filaments and fusiforms 4-9 days undisturbed: more complex flora with rods, filamentous forms 7-14 days: Vibrio species, spirochetes, more Gram-negative organisms Dental plaque is considered a biofilm adhered to the tooth surface. (wikipedia.org)
  • After some growth of early colonisers, the biofilm becomes more compliant to other species of bacteria, known as late colonisers. (wikipedia.org)
  • Our oral cavity houses various types of microbes including bacteria, protozoa, fungi and viruses, harboring over 700 bacterial species. (degruyter.com)
  • Although overgrowth of certain pathogenic bacteria have been indicated in some cardiometabolic diseases, it is still premature to consider oral microbiome as a suitable predictor for non-invasive diagnostic purpose. (degruyter.com)
  • Translocation of bacteria from oral cavity to intestine might exacerbate gut dysbiosis. (degruyter.com)
  • In the advanced stages of the disease, the pathogenic bacteria of dental plaque and their metabolic products may enter into the systemic circulation during mastication or mechanical procedures. (encyclopedia.pub)
  • Bacteria have always been associated with disease and have caused the human race much grief. (bvsalud.org)
  • Literature data have reported that certain Gram-negative anaerobe bacteria from the subgingival environment are important etiological agents of chronic periodontal disease. (journal-imab-bg.org)
  • Gum disease bacteria can be found in the brains of Alzheimer's patients. (intownsmilestudio.com)
  • having a healthy oral biofilm (your mouth has only the good bacteria) is protective against developing pancreatic cancer. (intownsmilestudio.com)
  • Formation of dental Pellicle Acquired enamel pellicle forms rapidly - Early pellicle Characterized by an absence of bacteria and their products. (medicpresents.com)
  • The need for retreatment may be attributed to either reinfection by oral bacteria or, more often, to the persistence and regrowth of microorganisms that were not eliminated during the previous treatment. (opendentistryjournal.com)
  • If not removed regularly, the biofilm undergoes maturation, which is connected with a progressive shift from a Gram-positive to a Gram-negative anaerobic species, which results in formation under the gingival surface, where bacteria grow profusely [ 1 ] . (encyclopedia.pub)
  • This connection is centered around so-called oral dysbiosis, a condition where imbalanced oral bacteria can lead to a range of health issues. (lumoral.com)
  • The oral cavity houses more than 700 types of bacteria. (lumoral.com)
  • The BJC study from 2017 was the first to show that virulence factors from gum disease bacteria could spread from the mouth to other parts of the body and take part in central mechanisms of cancer-related tissue destruction. (lumoral.com)
  • The links revealed so far between oral bacteria and cancer developments have inspired Prof. Sorsa's team to search ways to help prevent cancerous developments. (lumoral.com)
  • Actinomyces oris is an early colonizer and has two types of fimbriae on its cell surface, type 1 fimbriae (FimP and FimQ) and type 2 fimbriae (FimA and FimB), which contribute to the attachment and coaggregation with other bacteria and the formation of biofilm on the tooth surface, respectively. (biomedcentral.com)
  • Short-chain fatty acids (SCFAs) are metabolic products of oral bacteria including A. oris and regulate pH in dental plaques. (biomedcentral.com)
  • SCFAs affect the INAC-associated activities of the A. oris fimbrillins and non-fimbrillins during ionized and non-ionized acid formations in the form of co-culturing with other bacteria in the dental plaque but not impact the interaction of A. oris with streptococci. (biomedcentral.com)
  • Oral cavity contains millions of anaerobic bacteria like fusobacterium and actinomyces which acts on the protein of food materials and putrifies them. (likehealthylife.com)
  • If oral hygiene is not maintained properly the mouth becomes the seat for millions of bacteria which produce offenssive gases by degrading the food debris. (likehealthylife.com)
  • In patients with AD, oral bacteria were detected in brain tissues, and increased levels of pro-inflammatory cytokines were also detected. (metabiom.org)
  • The oral bacteria observed transiently in blood were broadly citrullinated in the mouth, and their in situ citrullinated epitopes were targeted by extensively somatically hypermutated ACPA B Cells encoded by RA blood plasmablasts. (metabiom.org)
  • Among the vast variety of bacteria, only very few are considered pathogenic and cause disease in humans. (amboss.com)
  • If a sufficient amount of bacteria is ingested (e.g., oral or contaminated foods), disease also occurs in immunocompetent individuals. (amboss.com)
  • Dental plaque is also known as microbial plaque, oral biofilm, dental biofilm, dental plaque biofilm or bacterial plaque biofilm. (wikipedia.org)
  • Bacterial plaque is one of the major causes for dental decay and gum disease. (wikipedia.org)
  • To understand the relationship between our bacterial microbiome and health, it is essential to define the microbiome in the absence of disease. (biomedcentral.com)
  • The bacterial microbiome of the human digestive tract contributes to both health and disease. (biomedcentral.com)
  • The widespread emergence of bacterial resistance to antibiotics has led to the concept of probiotic therapy for application in oral health. (bvsalud.org)
  • Nowadays, most studies focus on the antimicrobial properties of the irrigating solutions, involving both forms of bacterial growth, planktonic and biofilm. (opendentistryjournal.com)
  • Dental plaque is a community of microorganisms found on the surface of teeth or other hard surfaces like dentures and embedded in a matrix of polymers of both host and bacterial origin. (encyclopedia.pub)
  • The direct mechanism is connected with angiotensin-converting enzyme II (ACE-2) receptors, while the indirect mechanism is connected with inflammatory pathways and bacterial superinfections. (encyclopedia.pub)
  • While some bacterial species are beneficial for dental and overall health, in some cases, they can play a role in the development of serious systemic illnesses. (lumoral.com)
  • Even a thin biofilm can make anaerobic condition favourable for bacterial proliferation. (likehealthylife.com)
  • The bulk of the microorganisms that form the biofilm are Streptococcus mutans and other anaerobes, though the precise composition varies by location in the mouth. (wikipedia.org)
  • These microorganisms all occur naturally in the oral cavity and are normally harmless. (wikipedia.org)
  • Adverse microbial changes, both in composition and function, can act at several levels within the gut (stool and mucosal) and have also been described in the blood and oral cavity. (jci.org)
  • While dysbiosis in the oral cavity could be a source of systemic inflammation, current cirrhosis treatment modalities are targeted toward the gut-liver axis and do not address the oral microbiome. (jci.org)
  • Oral dysbiosis refers to the imbalance between symbionts and pathobionts in the oral cavity, posing potential threats to host cardiovascular health. (degruyter.com)
  • An essential condition for a microorganism to represent a probiotic of interest for oral health is its capacity to adhere to and colonize various surfaces of the oral cavity. (bvsalud.org)
  • Definition Dental Plaque "is a specific but highly variable structural entity, resulting from sequential colonization of microorganisms on tooth surfaces, restorations & other parts of oral cavity, composed of salivary components like mucin, desquamated epithelial cells, debris & microorganisms, all embedded in extracellular gelatinous matrix. (medicpresents.com)
  • The human oral cavity is a highly complex ecosystem in which the tooth- and soft-tissue surfaces offer distinct ecological niches for microbial colonization. (biomedcentral.com)
  • In the oral cavity, dentilisin not only contributes to gum disease but also triggers other enzymes that promote cancer. (lumoral.com)
  • This connection raises concerns about potential health issues related to dentilisin in the oral cavity, Prof. Sorsa stresses. (lumoral.com)
  • Saliva conains oxygen molecules which is needed to make oral cavity aerobic. (likehealthylife.com)
  • One of the most densely populated and diverse sites of the human body is the mouth and gastrointestinal tract (GI tract), which extends from the oral cavity to the anus. (stemcelldaily.com)
  • 10. Haffajee A, Sokransky S. Microbial etiological agents of destructive periodontal diseases. (journal-imab-bg.org)
  • This is a relevant aspect to take into consideration because microbial adherence to the dentin is the first step in colonization, including tubule invasion, and the origin of biofilm infections. (opendentistryjournal.com)
  • Imbalances of the microbiome, also referred to as microbial dysbiosis, could lead to a series of different diseases. (nature.com)
  • When the adjacent gingival soft-tissues are inflamed, the flow of serum-like transudate (gingival crevicular fluid, GCF) into the pocket increases and under the influence of this environmental perturbation, homeostasis in the subgingival microbial community can be disturbed giving rise to dysbiosis that predisposes the site to disease [ 3 ]. (biomedcentral.com)
  • Studies show that m aintaining a balanced microbial ecosystem in the mouth is crucial for oral health and it has a significant impact on how the body responds to various diseases. (lumoral.com)
  • These services are focused on microbial culture and antibiotic susceptibility testing of dental plaque/biofilm sampled from patients with periodontal disease or failing dental implants. (temple.edu)
  • Oral hygiene is important as dental biofilms may become acidic causing demineralization of the teeth (also known as dental caries) or harden into dental calculus (also known as tartar). (wikipedia.org)
  • Dental caries, periodontal disease and halitosis are among the oral disorders that have been targeted. (bvsalud.org)
  • It was shown that 40-50% of plaque remains after tooth brushing, and the effects of biofilm retention are clearly evident in the prevalence of caries, gingivitis and periodontal disease. (encyclopedia.pub)
  • In another report, the maximum concentrations of butyric (8.8 mM), propionic (33.7 mM), acetic (52.6 mM) and formic acids (5.8 mM) were also detected in dental plaques from caries-free and caries-susceptible young subjects [ 32 ]. (biomedcentral.com)
  • Caries are common in schoolgoing children and in those who donot maintain proper oral hygiene .Calcium and vitamin deficiency can also predispose caries. (likehealthylife.com)
  • Dysbiosis of both oral and gut microbiomes result in systemic inflammation and endotoxemia to cause liver dysfunction and even liver diseases (e.g . cirrhosis, nonalcoholic fatty liver disease and nonalcoholic steatohepatitis) [ 4 ]. (degruyter.com)
  • The recruitment criteria included a set of objective, composite measurements performed by healthcare professionals [ 10 ], defining this reference population and enabling this investigation to focus on defining the integrated oral, oropharyngeal, and gut microbiomes in the absence of host disease. (biomedcentral.com)
  • Cirrhosis development and progression involves several important interorgan communications, and recently, the gut microbiome has been implicated in pathophysiology of the disease. (jci.org)
  • The aim of this review article is to highlight the role of gut microbiome and inflammation in the pathophysiology of cirrhosis and to introduce the oral-gut-liver axis as a new perspective to consider in future research. (jci.org)
  • However, targeting oral microbiome might still provide preventive and therapeutic insights on cardiovascular diseases. (degruyter.com)
  • Moreover, translocation of oral microbes to the intestine aggravates gut microbiome dysbiosis. (degruyter.com)
  • It is therefore critically important to define the microbiome of healthy persons in order to detect significant variations both in disease states and in pre-clinical conditions to understand disease onset and progression. (biomedcentral.com)
  • Experimental evidence shows that the microbiome is needed for the health of the host and that alterations in the ecological equilibrium of microbes can lead to disease. (bvsalud.org)
  • We used a metatranscriptomic approach to obtain first insights into the metabolic changes induced by this stress hormone as well as which members of the oral microbiome respond to the presence of cortisol in the environment. (nature.com)
  • Our findings show that the stress hormone cortisol directly induces shifts in the gene expression profiles of the oral microbiome that reproduce results found in the profiles of expression of periodontal disease and its progression. (nature.com)
  • Among the environmental factors that may alter the equilibrium in host-microbiome homeostasis, host-stress is a known risk factor for a variety of diseases. (nature.com)
  • even after remission, the salivary microbiome of the two groups (oral disease and healthy) differed significantly. (metabiom.org)
  • Oral microbiome dysbiosis persisted even after dental treatment-induced disease remission with a sustained increased risk of disease when compared with healthy participants. (metabiom.org)
  • Dysbiosis, or an imbalanced oral microbiome, or ecosystem, can lead to various health issues ranging from common dental problems like cavities and gum disease to severe conditions such as heart disease, Alzheimer's disease, and diabetes. (lumoral.com)
  • In a fashion, chronic local inflammation in periodontal tissue promotes the secretion of pro-inflammatory cytokines into systemic circulation. (degruyter.com)
  • A deep understanding of the etiology and pathogenesis of periodontal disease and its chronic, inflammatory, and infectious nature generates the need to recognize the possibility that it may have deleterious effects on other body parts as well [ 2 ] [ 3 ] . (encyclopedia.pub)
  • Probiotics have proven to be effective in the treatment of several systemic and infectious diseases such as acute diarrhoea, Crohn's disease, cancer, immunodepressive states, inadequate lactase digestion, hyperlipidemia, liver diseases, infections with Helicobacter pylori, genitourinary tract infections and others 12 . (bvsalud.org)
  • Relationships among gingival crevicular fluid biomarkers, clinical parameters of periodontal disease, and the subgingival microbiota. (journal-imab-bg.org)
  • Interestingly, the removal of organic acids from cranberry juice lowered the cytotoxicity of the beverage for oral epithelial cells. (cranberryinstitute.org)
  • The secretion of IL-6 by lipopolysaccharide (LPS)-stimulated oral epithelial cells exposed to cranberry juice increased proportionally with the deacidification rate. (cranberryinstitute.org)
  • This pathogenic strain was able to survive inside the epithelial cells and trigger an inflammatory response that was milder when a thick mucus layer was present. (ibecbarcelona.eu)
  • Many studies have suggested the theory of focal infection in which an oral microorganism can migrate to adjacent or distant parts of the body. (encyclopedia.pub)
  • This review is an attempt to juxtapose the presence of periodontal infection in addition to systemic diseases such as cardiovascular disease, respiratory disorders, preeclampsia, glycemic control diseases, autoimmune disorders, and cancer. (encyclopedia.pub)
  • Periodontal illness, likewise referred to as gum disease, is an infection brought on by microorganisms, parasites, and infections. (healthdigesthq.com)
  • In infection with the pathogenic adherent invasive E. coli strain LF82, characteristic of Crohn's disease, we observed that this secreted mucus promoted the adhesion of the pathogen and at the same time had a protective effect upon its invasion. (ibecbarcelona.eu)
  • The disease caused by SARS-CoV-2 infection was named Coronavirus Disease 2019 (COVID-19). (encyclopedia.pub)
  • Chronic rhinosinusitis is one of the more common chronic diseases in the United States, and it affects those of all ages. (medscape.com)
  • Dental plaque, which leads to oral diseases, may be a risk factor causing a severe course of COVID-19 similar to those in above mentioned chronic diseases. (encyclopedia.pub)
  • As interventions designed to modulate oral dysbiosis may delay progression of cirrhosis, a better understanding of this process is of the utmost importance. (jci.org)
  • Microbiological data has been suggested by several studies as a useful indicator of disease progression, selection of an adjunctive antimicrobial administration, healing assessment and disease recurrence. (journal-imab-bg.org)
  • Therefore, it is important to understand the pathogenesis of cirrhosis and the underlying biological factors that can modulate disease outcomes to develop better preventive and treatment strategies. (jci.org)
  • Mechanism-based insights into the disease pathogenesis and association are highly relevant and shall be useful in avoiding any systemic complications. (encyclopedia.pub)
  • The role of inflammatory mediators in the pathogenesis of periodontal diseases. (journal-imab-bg.org)
  • Similar to the effect of gut microbiota on cirrhosis, emerging evidence also suggests that there is a possible link between a dysbiotic oral microenvironment and liver diseases. (jci.org)
  • La majoria d'articles són en anglès, amb alguns en castellà o altres llengües, y la majoria té resum en castellà, gràcies al Biocodex Microbiota Insitute (que no fa els resums en català). (gapsfamily.org)
  • Worse inflammatory profile in omnivores than in vegetarians associates with the gut microbiota composition. (gapsfamily.org)
  • Some recent evidence also suggests a role of the human oral microbiota in the development of digestive cancer s. (lumoral.com)
  • Importantly, oral dysbiosis promotes cardiovascular pathophysiology through different mechanisms. (degruyter.com)
  • Some common mechanisms by which oral dysbiosis increases cardiovascular risks have been illustrated in Figure 1 . (degruyter.com)
  • Common mechanisms of oral dysbiosis-promoted cardiovascular pathophysiology. (degruyter.com)
  • The modulations of the immunity, caused by dysbiosis during development, can increase the susceptibility to allergic diseases. (ibecbarcelona.eu)
  • Recent studies have revealed that oral dysbiosis may even be involved in the development of life-threatening digestive cancers. (lumoral.com)
  • Translocation can cause systemic infections (such as bacteremia or sepsis), local infections (such as peritonitis or abscesses) or chronic inflammation (such as inflammatory bowel disease or rheumatoid arthritis). (stemcelldaily.com)
  • Periodontal disease is more common in individuals with #Rheumatoid Arthritis (RA) who have detectable anti-citrullinated protein antibodies (ACPAs). (metabiom.org)
  • Only recently insights were obtained into how T. forsythia gains access to MurNAc in its oral habitat, enabling synthesis of the own PGN cell wall. (karger.com)
  • Dental plaque is a biofilm that attaches to tooth surfaces, restorations and prosthetic appliances (including dentures and bridges) if left undisturbed. (wikipedia.org)
  • These microbes can inhabit both hard surfaces of teeth and soft surfaces of oral mucosa. (degruyter.com)
  • Tooth-associated communities were distinct, but not entirely dissimilar, from other oral surfaces. (biomedcentral.com)
  • May involve the interaction of phosphate groups with calcium ions in saliva to form "bridges" Protective functions of early enamel pellicle: protection , lubrication by decreasing frictional forces, may selectively concentrate antimicrobial substances such as immunoglobulins, lysozyme, and cystatins at different oral surfaces. (medicpresents.com)
  • Most of them attach to different surfaces to form some type of biofilm matrix that is highly structured and spatially organized. (encyclopedia.pub)
  • Rams, T.E., Alwaqyan, A.Y. In vitro performance of DIAGNOdent laser fluorescence device for dental calculus detection on human tooth root surfaces. (temple.edu)
  • While the more severe forms of periodontal disease associated with alveolar bone loss are less frequent, gingivitis is widespread at all ages and is the most common form of periodontal disease. (encyclopedia.pub)
  • Several etiologies, with the most prevalent being viral hepatitis, alcoholic liver disease (ALD), and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH), can cause cirrhosis. (jci.org)
  • The study also suggested that dental problems were more prevalent in males (41-50 years of age) than females. (scielo.br)
  • Oral diseases caused by various microorganisms are common around the world. (scielo.br)
  • When microorganisms and healthy proteins from saliva mix with each other, plaque as well as biofilm are created. (healthdigesthq.com)
  • Periodontal disease is caused by a combination of viruses, microorganisms, and parasites. (healthdigesthq.com)
  • In summary, the normal flora of the mouth and GI tract is a complex and dynamic community of microorganisms that interacts with the host and the environment, and influences various aspects of human health and disease. (stemcelldaily.com)
  • S. mutans and other anaerobes are the initial colonisers of the tooth surface, and play a major role in the establishment of the early biofilm community. (wikipedia.org)
  • NAFLD is a spectrum of liver disease associated with metabolic syndrome and obesity that consists of simple fatty infiltration (steatosis), inflammation with steatosis (steatohepatitis or NASH), and varying degrees of fibrosis that ultimately lead to cirrhosis. (jci.org)
  • Both plaque and biofilm can damage teeth as well as various other structures in the mouth, and also if left neglected, can bring about the development of calculus (hardened deposits) on the teeth. (healthdigesthq.com)
  • Patients suffering from diabetes, hypertension, obesity, asthma, and kidney and liver disease are in the high-risk group for severe COVID-19 symptoms [ 6 ] . (encyclopedia.pub)
  • The current article aims to review the beneficial role of some probiotic species, their mode of action and clinical effectiveness especially in periodontal disease and halitosis. (bvsalud.org)
  • The Oral Microbiology Testing Service (OMTS) Laboratory at the Kornberg School of Dentistry provides commercial diagnostic testing services to practicing dentists and several dental school clinical programs in the U.S. The OMTS Laboratory is licensed by the Pennsylvania Health Department for clinical periodontal microbiology analysis. (temple.edu)
  • Zirconia dental implants: a clinical, radiographic, and microbiologic evaluation up to 3 years. (docksci.com)
  • Forty-five chronic ( 1 week) randomised controlled trials assessing CVD risk factors including endothelial (dys)function, blood pressure (BP), blood lipids and inflammatory biomarkers were included. (cranberryinstitute.org)
  • 1.4 ] [ #Periodontal abscess ] - periodontopathogens can be disseminated through the blood flow to other body parts where they may enhance inflammatory processes that can lead to the development or exacerbation of #Atherosclerosis . (metabiom.org)
  • In the arena of periodontal medicines, the studies of past decades suggest a link between human periodontal afflictions and certain systemic disorders such as cardiovascular diseases, diabetes mellitus, respiratory disorders, preterm birth, autoimmune disorders, and cancer. (encyclopedia.pub)
  • If left untreated and undiagnosed, periodontal disease contributes to the development and spread of cancer and cancer deaths - not only from oral cancer, but especially pancreatic cancer, explains Timo Sorsa , Professor of Oral and Maxillofacial Diseases at the University of Helsinki, findings of the study. (lumoral.com)