Loading...
  • Staphylococcus
  • Preliminary research shows healthy pores are only colonized by P. acnes, while unhealthy ones universally include the nonpore-resident Staphylococcus epidermidis, amongst other bacterial contaminants. (wikipedia.org)
  • Whether this is a root causality, just opportunistic and a side effect, or a more complex pathological duality between P. acnes and this particular Staphylococcus species is not known. (wikipedia.org)
  • efficacy
  • Evaluation of the clinical efficacy of the 1,450 nm laser in acne vulgaris: a randomized split-face, investigator-blinded clinical trial. (semanticscholar.org)
  • In a 2013 multicenter, randomized clinical study with a total of 184 Japanese patients with moderate to severe acne, adapalene 0.1% gel plus nadifloxacin 1% cream (combination therapy) showed a significant efficacy in decrement of inflammatory papulopustular lesions. (wikipedia.org)
  • However, for acne vulgaris, several recent double blind studies have shown consistently superior efficacy for tazarotene and roughly equal tolerability for both treatments. (wikipedia.org)
  • Most often treatment of hyperpigmentation caused by melanin overproduction (such as melasma, acne scarring, liver spots) includes the use of topical depigmenting agents, which vary in their efficacy and safety, as well as in prescription rules. (wikipedia.org)
  • follicles
  • Acne vulgaris typically affects the areas of skin with the densest population of sebaceous follicles (eg, face, upper chest, back). (medscape.com)
  • Acne, also known as acne vulgaris, is a long-term skin disease that occurs when hair follicles are clogged with dead skin cells and oil from the skin. (wikipedia.org)
  • Although HS shares certain common features with acne vulgaris, such as a tendency to clog skin follicles with skin cell debris, the condition otherwise lacks the defining features of acne and is therefore considered a distinct skin disorder. (wikipedia.org)
  • antimicrobial
  • Azerizin is claimed to be a proprietary blend of the natural ingredients nicotinamide, azelaic acid, quercetin and curcumin that purportedly combine the anti-inflammatory and antimicrobial properties, along with inhibiting effects on sebum production. (wikipedia.org)
  • lesion
  • Outcome measures used in the trials included lesion counts, acne grades/severity scores, doctors' and participants' global assessments, adverse effects , and dropout rates. (cochrane.org)
  • Previous studies confirm that exist a reduced expression of CD1d by keratinocytes in acne lesion, what can be interpreted as a low antigen-present function. (clinicaltrials.gov)
  • The healing of an acne lesion includes three successive phases . (jle.com)
  • minocycline
  • In summary, there is no evidence to support the first-line use of minocycline in the treatment of acne. (cochrane.org)
  • All of the trials showed that, on average, people treated with minocycline experienced an improvement in their acne. (cochrane.org)
  • The only conclusion that we could make was that people treated with minocycline for acne are at a significantly greater risk of developing an autoimmune (lupus-like) syndrome than those given tetracycline or no treatment. (cochrane.org)
  • To assess new evidence on the effects of minocycline for acne vulgaris. (cochrane.org)
  • noninflammatory
  • Acne can present as noninflammatory lesions, inflammatory lesions, or a mixture of both, affecting mostly the face but also the back and chest. (medscape.com)
  • Specifically, tazarotene reduced the number of noninflammatory and inflammatory lesions at 4, 8, and 12 weeks -- all timepoints examined during treatment. (wikipedia.org)
  • rosacea
  • Azerizin was developed at Elorac for use as an adjunct in the management of acne vulgaris and rosacea. (wikipedia.org)
  • Acne inversa (L. invertō, "upside down") and acne rosacea (rosa, "rose-colored" + -āceus, "forming") are not true forms of acne and respectively refer to the skin conditions hidradenitis suppurativa (HS) and rosacea. (wikipedia.org)
  • treatments
  • Its use has lessened due to safety concerns (including potentially irreversible pigmentation ), a relatively high cost, and no evidence of any greater benefit than other acne treatments. (cochrane.org)
  • Disease
  • 2002. Acne Vulgaris: A Disease of Western Civilization, Colorado State University. (scribd.com)
  • Acne is the most common skin disease of adolescence, and in most cases it clears spontaneously. (cochrane.org)
  • P. acnes can be found in bronchoalveolar lavage of approximately 70% of patients with sarcoidosis and is associated with disease activity, but it can be also found in 23% of controls. (wikipedia.org)
  • Acne vulgaris is the disease most commonly associated with P. acnes infection. (wikipedia.org)
  • In 2015, acne was estimated to affect 633 million people globally, making it the 8th most common disease worldwide. (wikipedia.org)
  • affects
  • Acne commonly occurs in adolescence and affects an estimated 80-90% of teenagers in the Western world. (wikipedia.org)
  • infection
  • Although antibiotics have been used for decades to treat acne vulgaris, acne is not a traditional infection. (aafp.org)
  • P. acnes is an opportunistic pathogen, causing a range of postoperative and device-related infections e.g., surgery, post-neurosurgical infection, joint prostheses, shunts and prosthetic heart valves. (wikipedia.org)
  • Infection describes the interaction between the action of microbial invasion and the reaction of the body's inflammatory response - the two components are considered together when discussing an infection, and the word is used to imply a microbial invasive cause for the observed inflammatory reaction. (wikipedia.org)
  • treat
  • Consequently, some authors argued that it should not be used to treat relatively harmless diseases like acne vulgaris, risking the development of quinolone resistances. (wikipedia.org)
  • The gel is used on the skin to treat light to medium acne vulgaris in people 12 years and older. (wikipedia.org)