• Cancer
  • Notably, this obesity-inflammation-aromatase axis provides a plausible explanation for increased rates of post-menopausal, hormone receptor-positive breast cancer associated with obesity and hence may offer targets for interventions to attenuate risk or improve prognosis. (aacrjournals.org)
  • migration
  • Although the response is initiated to protect the central nervous system from the infectious agent, the effect may be toxic and widespread inflammation as well as further migration of leukocytes through the blood-brain barrier. (wikipedia.org)
  • response
  • Moreover, inflammation-induced MerTK cleavage can limit this response, as shown by the improvement in resolution in a new MerTK-cleavage resistant mouse model. (pnas.org)
  • role
  • Inflammation is now believed to play a major role in the pathopathophysiology of AKI. (hindawi.com)
  • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance," The Journal of Clinical Investigation , vol. 112, no. 12, pp. 1821-1830, 2003. (hindawi.com)
  • identify
  • A key future goal is to identify biomarkers that accurately report adipose inflammation, both for identification of at-risk individuals and to assess the efficacy of interventions. (aacrjournals.org)
  • Journal
  • J. Ye and O. P. McGuinness, "Inflammation during obesity is not all bad: evidence from animal and human studies," American Journal of Physiology , vol. 304, no. 5, pp. (hindawi.com)