Inflammation genes beta chemokine receptors chemokine ccl3. Medical search. Frequent questions

CCL4, also known as macrophage inflammatory protein 1 beta (MIP-1 beta ) is a 7.8 kDa beta chemokine that is secreted at sites of inflammation by activated leukocytes, lymphocytes, vascular endothelial cells, and pulmonary smooth muscle cells (1, 2). (rndsystems.com)
CCL4 attracts a variety of immune cells to sites of microbial infection as well as to other pathologic inflammation such as allergic asthma and ischemic myocardium (3 - 8). (rndsystems.com)
CCL4 is secreted from activated monocytes as a heterodimer with CCL3/MIP-1 alpha (9). (rndsystems.com)
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F: Candida albicans enhanced the production of the CCR5-interacting chemokines CCL3, CCL4, and CCL5, and stimulates the production of interferon-a and the restriction factors APOBEC3G, APOBEC3F, and tetherin (BST2) in macrophages Rodriguez et al, 2013 . (polygenicpathways.co.uk)
BST2 bone marrow stromal cell antigen 2 (Tetherin): Candida albicans enhanced the production of the CCR5-interacting chemokines CCL3, CCL4, and CCL5, and stimulates the production of interferon-a and the restriction factors APOBEC3G, APOBEC3F, and tetherin (BST2) in macrophages Rodriguez et al, 2013 . (polygenicpathways.co.uk)
Activation of myofibroblasts occurs in response to different stimuli, including growth factors such as transforming growth factor beta (TGF-β) and platelet-derived growth factor (PDGF), pro-inflammatory cytokines such as interleukin 1 (IL-1), IL-13 and IL-17, as well as CC chemokines like CCL2, CCL3 and CCL4, and lipid mediators released by immune and non-immune cells [ 6 ]. (biomedcentral.com)
This plasmablast-like phenotype can be reconciled in human melanomas where plasmablast-like cells also express T cell-recruiting chemokines CCL3, CCL4, CCL5. (regenerativemedicine.net)

Interferon pathway-related cytokines/chemokines, including interleukin (IL) 18, macrophage inflammatory protein 3α, and IL-33, were elevated, but tumor necrosis factor-α, IL-6, CXCL8 (formerly IL-8), and cytokines acting through C-C chemokine receptor 2 and CCR5 were lower among case-patients than controls. (cdc.gov)
Interferon pathway activation and cytokines/chemokines acting through CCR2 and CCR5 improved health results among children with severe CCHF. (cdc.gov)
[15] The production of NF-kB1 and ReIA increases rates of gene transcription of cytokines and inflammatory-inducing molecules. (wikidoc.org)
Outcomes Diet-induced weight problems reduced cardiac blood sugar fat PTK787 2HCl burning capacity GLUT and AMP-activated proteins kinase (AMPK) amounts which was connected with increased degrees of macrophages toll-like receptor 4 suppressor of cytokine signaling 3 (SOCS3) and cytokines in center. (cancer-ecosystem.com)
Acute lipid infusion triggered inflammation and elevated local degrees of macrophages C-C theme chemokine receptor 2 SOCS3 and cytokines in center. (cancer-ecosystem.com)
This was accompanied by enhanced gene expression of proinflammatory cytokines and chemokines, as well as more recruited inflammatory cells into the intestine. (biomedcentral.com)
They are grouped into one family because the receptor complex of each cytokine contains two (IL-6 and IL-11) or one molecule (all others cytokines) of the signaling receptor subunit gp130. (antibodies-online.cn)
In 2001, six immune mediators (IL-10, IL-19, IL-20, IL-22, IL-24, and IL-26) were grouped into the so-called IL-10 family of cytokines based on their similarities with respect to the structure and location of their encoding genes, their primary and secondary protein structures, and the receptor complexes used. (antibodies-online.cn)
As such, the role of P. falciparum -derived Hz ( Pf Hz) in mediating suppression of erythropoiesis through its ability to cause dysregulation in pro- and anti-inflammatory cytokines, growth factors, chemokines, and effector molecules is discussed in detail. (ijbs.com)

The ligands of this receptor include CCL3 (or MIP-1 alpha), CCL5 (or RANTES), CCL7 (or MCP-3), and CCL23 (or MPIF-1). (wikipedia.org)
CCL5 is a unique chemokine with distinct stage and cell-type specificities for regulating inflammation, but how these specificities are achieved and how CCL5 modulates immune responses is not well understood. (nature.com)

Chemokine ccl2. (lookformedical.com)
CCR receptors with specificity for CHEMOKINE CCL2 and several other CCL2-related chemokines. (lookformedical.com)
Another reported that IL-10, C-X-C motif chemokine ligand 10 (CXCL-10, formerly IFN-γ inducible protein 10) and CC chemokine ligand 2 (CCL2, formerly monocyte chemoattractant protein 1) levels were higher in patients with high viral loads ( 12 ), but patients with severe disease had higher levels of CXCL10 and CCL2 than did patients with less-severe cases. (cdc.gov)

We examined cytokine/chemokine profiles of 9/12 case-patients compared with healthy controls at 3 time intervals. (cdc.gov)
The degree of methylation affects the expression of target genes and has a significant impact on cell proliferation, apoptosis, cytokine secretion, and cell activity ( 6 , 7 ). (frontiersin.org)
The chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MGSA-α). (wikidoc.org)
Changes in ST mitogen-activated protein kinase (MAPK) activation were assessed by immunoblotting and mRNA expression levels of selected cytokine and chemokines in primary ST bound by iRBC were determined using real-time, reverse transcription PCR. (biomedcentral.com)
In addition, secreted cytokine and chemokine proteins were assayed by standard ELISA, and chemotaxis of PBMC was assessed using a two-chamber assay system. (biomedcentral.com)
Separation of the Lin- cells into Thy-1 and Thy-1lo subsets showed that the growth of Thy-1lo Lin- cells is directly inhibited by MIP-1 alpha and TGF beta regardless of the cytokine used to stimulate growth (IL-3), GM-CSF, or CSF-1). (ox.ac.uk)

Beta-catenin acts as an intracellular signal transducer in the Wnt signaling pathway. (plurisomes.com)
KEGG enrichment and gene set enrichment analysis (GSEA) showed that a large number of genes were enriched in inflammatory immune-related pathways, such as the toll-like receptor signaling pathway. (frontiersin.org)
The aryl hydrocarbon receptor (AhR), a member of the bHLH-Per-Arnt-Sim subfamily, is a ligand-activated transcription factor reported to regulate nervous system development in both invertebrates and vertebrates, but the functions that AhR signaling pathway may have for mammalian cerebral cortex development remains elusive. (waseda.jp)

Using mice with an engineered ERCC1-XPF defect in tissue-infiltrating macrophages, we provide evidence for a fundamental mechanism by which irreparable DNA damage triggers an exosome-based, metabolic reprogramming that leads to chronic inflammation and tissue pathology in NER progeroid syndromes and likely also during aging. (nature.com)
We analyzed the gene expression profiles of individual monocyte-derived brain macrophages responding to TBI using single-cell RNA sequencing. (biomedcentral.com)
Also unexpectedly, individual TBI macrophages simultaneously expressed high levels of signature polarization genes across two or three different polarization states and in several distinct and seemingly incompatible combinations. (biomedcentral.com)
Single-cell gene expression profiling demonstrated that monocytic macrophages in TBI are not comprised of distinctly polarized subsets but are uniquely and broadly activated. (biomedcentral.com)
Both in vitro and in vivo studies demonstrate that with specific stimuli, human and mouse macrophages can polarize towards functionally divergent subsets, each possessing a distinct phenotype and gene expression profile [ 10 - 13 ]. (biomedcentral.com)
ALOX5 arachidonate 5-lipoxygenase: macrophages infected with Candida albicans, Aspergillus flavus or Aspergillus fumigatus or treated with Curdlan, a selective agonist of pattern recognition receptor for fungi Dectin-1, displays increased expression of ALOX5, ALOX15 and PTGS2 Karnam et al, 2015 . (polygenicpathways.co.uk)
Notably, these recruited macrophages may have distinct metabolic, proliferative, and inflammatory gene expression than resident AMs (Mould et al. (biomedcentral.com)
The lung compartment is later experienced CCR2 dependent influx of monocytes, which are later differentiated into monocyte derived alveolar macrophages (MoAM) that can drive lung inflammation and lung fibrosis. (biomedcentral.com)
Further, we uncovered several ligand-receptor pairs lining tumor cells and macrophages. (biomedcentral.com)

C-C chemokine receptor type 1 is a protein that in humans is encoded by the CCR1 gene. (wikipedia.org)
A CC chemokine with specificity for CCR1 RECEPTORS and CCR5 RECEPTORS. (lookformedical.com)
Individuals that suffered from severe COVID-19 show reduced frequencies of T cell, mucosal-associated invariant T cell (MAIT) and dendritic cell (DC) subsets and altered chemokine receptor expression on several subsets, such as reduced levels of CCR1 and CCR2 on monocyte subsets. (bvsalud.org)
Description: MIP-3 is a CC chemokine that signals through the CCR1 receptor. (scientificsupplyandequipment.com)

This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CXCR1, are found to form a gene cluster on chromosome 3p. (wikipedia.org)
It has specificity for CCR2 RECEPTORS. (lookformedical.com)

CCR receptors with specificity for CHEMOKINE CCL1. (lookformedical.com)

and CC chemokine ligand-3, indicative of an activated, proinflammatory state. (diabetesjournals.org)
Moreover, these receptors are functional, as treatment of FRT tissue cells with ligands for TLR and NOD induces production of proinflammatory CXCL8 [ 13 ], and those receptors actively participate in immune response to pathogens, as Neisseria gonorrhea and HIV-1 [ 14 ]. (hindawi.com)
Presence of inflammation was characterized on the basis of proinflammatory gene expression, monocyte trafficking, and activation of microglia. (sciencehealthandmore.com)

Chemokines and their receptors, which mediate signal transduction, are critical for the recruitment of effector immune cells to the site of inflammation. (wikipedia.org)
The experiments show that the responses of genes in the blood and lymph cells of the mice are connected to those in the muscle cells. (elifesciences.org)
In addition, chemokines regulate plethora of biological processes of hematopoietic cells to lead cellular activation, differentiation and survival. (genome.jp)
The chemokine signal is transduced by chemokine receptors (G-protein coupled receptors) expressed on the immune cells. (genome.jp)
Transcript analysis of B cells revealed that genes involved in allo-immune pathway were downregulated in TOT. (bvsalud.org)
The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. (cancerindex.org)
Activation of LT-β receptors is capable of inducing cell death of cancerous cells and suppressing tumor growth. (wikidoc.org)
γδ T cells express unique T cell receptor (TCR) γ and TCR δ chains, with structural and functional heterogeneity. (explorationpub.com)
Taking advantage of the diverse γδ TCR repertoire or other ligand-receptor interactions, γδ T cells can recognize a broad spectrum of tumor-associated antigens (TAAs) in a major histocompatibility complex (MHC)-independent manner, thereby activating downstream pleiotropic effects. (explorationpub.com)
Sustained inflammation and chronic wound healing response often lead to intestinal fibrosis, a condition defined by an excessive accumulation of extracellular matrix (ECM) proteins produced by activated myofibroblasts, which are alpha smooth muscle actin (α-SMA)-expressing cells. (biomedcentral.com)
Cytotoxic T cells swarm by homotypic chemokine signalling. (peprotech.com)
Significant downregulation of beta-defensin1 gene (DEFB1) expression was observed when human bronchial epithelial cells (HBEpCs) were exposed to IAV. (cdc.gov)
In conclusion, the reduction in IAV copy number in DEFB1 overexpressing cells suggests that beta-defensin-1 plays a key role in regulating IAV survival through STAT3 and is a potential target for antiviral drug development. (cdc.gov)
Here we show that tumor associated B cells are vital to melanoma associated inflammation. (regenerativemedicine.net)
Depletion of B cells in melanoma patients by anti-CD20 immunotherapy decreases tumor associated inflammation and CD8+ T cell numbers. (regenerativemedicine.net)
Tumor associated B cells therefore orchestrate and sustain melanoma inflammation and may represent a predictor for survival and response to immune checkpoint blockade therapy. (regenerativemedicine.net)
Both transforming growth factor beta (TGF beta) and macrophage inflammatory protein 1 alpha (MIP-1 alpha) have been shown to be multifunctional regulators of hematopoiesis that can either inhibit or enhance the growth of hematopoietic progenitor cells (HPC). (ox.ac.uk)
In contrast, two other stem cell populations (0% to 15% Höechst 33342/Rhodamine 123 [Hö/Rh123] and Lin-Sca-1+ cells) were markedly inhibited by TGF beta and unaffected by MIP-1 alpha. (ox.ac.uk)
Furthermore, MIP-1 alpha has no effect on high proliferative potential colony-forming cells 1 or 2 (HPP-CFC/1 or /2) colony formation in vitro, whereas TGF beta inhibits both HPP-CFC/1 and HPP-CFC/2. (ox.ac.uk)

Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. (wikipedia.org)
AMs are partially depleted at the peak of viral-induced inflammation, followed by the regeneration of AM pools by AM proliferation and monocyte differentiation into new AMs (Li et al. (biomedcentral.com)

G-/GMCSF activates the JAK family of receptor tyrosine kinases, which unfolds its activity by not only regulating enzymes and target proteins within its local milieu, but importantly also by activating the STAT family of transcription factors, which subsequently dimerize and translocate to the cell nucleus to regulate gene expression[ 13 ]. (biomedcentral.com)
when these proteins bind to pattern recognition receptors in microglia and astroglia, they trigger an innate immune response characterized by the release of inflammatory mediators. (biomedcentral.com)

These inflammatory signatures included phagocyte-restricted expression of chemokines, such as CXCL10 and CCL3, and the broad expression of IFN-induced genes, such as MX1, ISG15, and IFIT1. (bvsalud.org)

Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. (wikipedia.org)
Cell surface glycoproteins that bind to chemokines and thus mediate the migration of pro-inflammatory molecules. (lookformedical.com)
We have compared four licensed vaccines with known safety profiles, as well as three agonists of Toll-like receptors (TLRs) with known inflammatory potential, to elucidate the transcriptomic profile of an acceptable response to vaccination versus that of an inflammatory reaction. (elifesciences.org)
Inflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. (genome.jp)
Due to the significant role of inflammation in the pathogenesis of AD, several inflammatory mediators have been proposed as AD markers, such as TNF-α, IL-1β, Iba-1, GFAP, NF-κB, TLR2, and MHCII. (biomedcentral.com)
In this review, we focus mainly on the relationship between inflammation and AD through topics ranging from neurodegeneration to the roles of highly insoluble Aβ deposits and neurofibrillary tangles as inflammatory stimuli in the brains of AD patients [ 10 ]. (biomedcentral.com)
The actual fact that severe lipid infusion escalates the inflammatory response and impairs myocardial blood sugar metabolism like the ramifications of high-fat nourishing suggests the function of nutritional tension in the activation of toll-like receptor (TLR) 4 signaling and irritation in center. (cancer-ecosystem.com)
Designed to study chronic inflammatory diseases, immune-related adverse affects, and autoimmune disease, this 770 gene panel combines comprehensive content and the robustness of the nCounter assay. (canopybiosciences.com)
However, the gene content provides powerful immune system information for the research of any autoimmune or chronic inflammatory disease. (canopybiosciences.com)
Distinct and overlapping direct effects of macrophage inflammatory protein-1 alpha and transforming growth factor beta on hematopoietic progenitor/stem cell growth. (ox.ac.uk)

Chemokine CCL8 has specificity for CCR3 RECEPTORS and CCR5 RECEPTORS. (lookformedical.com)
Chemokine receptor 5 (CCR5) has gained attention as therapeutic target in various malignancies. (cancerindex.org)

Group of chemokines with adjacent cysteines that are chemoattractants for lymphocytes, monocytes, eosinophils, basophils but not neutrophils. (lookformedical.com)
As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. (wikidoc.org)
PF4 is chemotactic for neutrophils , fibroblasts and monocytes , and interacts with a splice variant of the chemokine receptor CXCR3 , known as CXCR3B. (wikidoc.org)

This chemokine is released from alpha-granules of activated platelets during platelet aggregation, and promotes blood coagulation by moderating the effects of heparin -like molecules. (wikidoc.org)
Genome-wide association studies (GWAS) identified strong associations between severe disease and several chemokine receptors and molecules from the type I interferon pathway. (bvsalud.org)

This gene encodes a member of the beta chemokine receptor family, which belongs to G protein-coupled receptors. (wikipedia.org)
The receptors are members of the seven-transmembrane G protein-coupled receptor family. (lookformedical.com)

A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. (lookformedical.com)

A detailed examination and comparative analysis of these transcriptomes revealed a set of novel biomarkers that are reflective of inflammation after vaccination. (elifesciences.org)
These biomarkers are readily measurable in the peripheral blood, providing useful surrogates of inflammation, and provide a way to select candidates with acceptable safety profiles. (elifesciences.org)
were able to identify a set of genes (known as "biomarkers") that are associated with inflammation in animals. (elifesciences.org)
These biomarkers can be used to spot early on whether a new treatment is triggering inflammation. (elifesciences.org)

Among the results was evidence that there was differential chemokine mRNA expression by the papilloma tissues, which suggested that the virus might be able to polarize the patients' innate immune responses. (biomedcentral.com)

Since HIV-1 activates the type I interferon system, which signals via interferon-α receptor (IFNAR) 1 and 2, this study investigated the potential role of IFNAR1 in HIV-induced neurotoxicity. (biomedcentral.com)

A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. (lookformedical.com)
After receptor activation, the alpha- and beta-gamma-subunits of G protein dissociate to activate diverse downstream pathways resulting in cellular polarization and actin reorganization. (genome.jp)
Formation of LT-α 1 -β 2 complex enables binding to LT-β receptors and subsequent activation of signaling pathways. (wikidoc.org)
After LT-β receptor activation, IKK-α, β, and γ are produced, which increases degradation of I-κB , an inhibitor or NF-kB, and produce NF-kB1 (p50) and ReIA (p60). (wikidoc.org)
Not only does prolonged stress cause the activation of microglia but also inflammation of the hippocampus is the major issue in short-term memory loss. (sciencehealthandmore.com)
Macrophage polarization programs, commonly referred to as "classical" and "alternative" activation, are widely considered as distinct states that are exclusive of one another and are associated with different functions such as inflammation and wound healing, respectively. (biomedcentral.com)
The analysis of signature polarization genes by single-cell RNA sequencing revealed the presence of diverse activation states, including M(IL4), M(IL10), and M(LPS, IFNγ). (biomedcentral.com)
LF82 also potentiated TGF-β1-stimulated epithelial-mesenchymal transition and myofibroblast activation in IECs, by further inducing gene expression of the main mesenchymal cell markers FN1 and VIM and downregulating the IEC marker OCLN . (biomedcentral.com)
Impaired dendritic growth and positioning of cortical pyramidal neurons by activation of aryl hydrocarbon receptor signaling in the developing mouse. (waseda.jp)
To this end, we produced mice expressing either constitutively active-AhR (CA-AhR), which has the capacity for ligand-independent activation of downstream genes, or AhR, which requires its ligands for activation. (waseda.jp)

Like the CHEMOKINES themselves, the receptors can be divided into at least three structural branches: CR, CCR, and CXCR, according to variations in a shared cysteine motif. (lookformedical.com)
Recombinant Murine MIP-1β is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. (peprotech.com)

This can include swelling of tissues (known as inflammation), which in rare cases, can be life threatening. (elifesciences.org)
Toward understanding the immune mechanism(s) that prevents patients with RRP from clearing or controlling their HPV infection, we previously performed a paired messenger RNA (mRNA) microarray study that characterized the repertoires of genes expressed in papillomas versus those expressed by autologous clinically normal laryngeal tissues ( 6 ). (biomedcentral.com)

In this study, we have characterized the T H 2-like chemokine profile (CCL17, CCL18, CCL20, CCL22) in patients with RRP and asked whether it was modulated in patients who had achieved significant clinical improvement. (biomedcentral.com)

Current theories on regulation of inflammation center on anti-tumor T cell responses. (regenerativemedicine.net)

[6] [7] CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis , arteriogenesis , inflammation , wound healing , and tumorigenesis . (wikidoc.org)

In addition, the prostate gland has been associated with chronic inflammation [5], a condition linked to elevated oxidative stress. (pharmaceuticalintelligence.com)

Recent studies indicate that some hematopoietic growth factors, namely granulocyte macrophage colony stimulating factor (GMCSF) and granulocyte colony stimulating factor (GCSF), are abundantly released in the tumor microenvironment and play a key role in regulating tumor-nerve interactions and tumor-associated pain by activating receptors on dorsal root ganglion (DRG) neurons. (biomedcentral.com)
Tumor associated inflammation predicts response to immune checkpoint blockade in human melanoma. (regenerativemedicine.net)

A CC-type chemokine secreted by activated MONOCYTES and T-LYMPHOCYTES. (lookformedical.com)

PGE 2 can bias the adaptive immune response away from an effective T H 1-like pattern ( 16 ), and can enhance expression of T H 2-like chemokines by innate immunocytes ( 16 , 17 ). (biomedcentral.com)
As a member of the TNF family , LT-α binds to various receptors and activates the NF-κB pathway , thus promoting immune regulation through the innate immune response. (wikidoc.org)
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. (peprotech.com)

TGF-α is related to EGF and binds to the EGF receptor, whereas TGF-β is structurally distinct from TGF-α. (antibodies-online.cn)
Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. (peprotech.com)

The type I IFNs (IFNα/β) bind to a specific IFN-α/β receptor (IFNAR) that consists of IFNAR1 and IFNAR2 chains [ 24 ]. (biomedcentral.com)
The iRBC bind to receptors expressed by the syncytiotrophoblast (ST). How ST responds to this interaction remains poorly understood. (biomedcentral.com)

Experimentally confirmed target genes were identified for the 73 diagnostic miRNAs, from which proliferation genes were selected from CRISPR-Cas9/RNA interference (RNAi) screening assays. (cdc.gov)

This, in turn, establishes chronic inflammation and tissue pathology in mice with important ramifications for DNA repair-deficient, progeroid syndromes and aging. (nature.com)
Chronic inflammation of the digestive tract. (canopybiosciences.com)

The gene for human PF4 is located on human chromosome 4 . (wikidoc.org)
[8] The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines. (wikidoc.org)
[1] [9] The gene of LT-α is located on chromosome 6 and is in close proximity of the gene encoding major histocompatibility complex . (wikidoc.org)

Examples include: antimalarial agents such as chloroquine and hydroxychloroquine, antivirals such as lopinavir/ritonavir and remdesivir, and tocilizumab as an anti-interleukin 6 (IL-6) receptor antibody ( 21 - 24 ). (frontiersin.org)

Thus, the change in expression of these three plasma T H 2-like chemokines may, with future studies, prove to serve as a useful biomarker for predicting disease prognosis. (biomedcentral.com)
ScRNA-seq of PBMCs was analyzed using 20 cell surface marker antibody sequencing to annotate clusters and 399 immune response panel to identify gene expression. (bvsalud.org)
Differences in cellular distribution and gene expression were compared among the three groups. (bvsalud.org)
In transcript analysis, genes associated with inflammation were decreased, while expression levels of CCR6 in Tregs were increased in TOT. (bvsalud.org)
Similarly, expression of genes involved in neurotransmission reveals sex-dependent effects of IFNAR1KO and HIVgp120. (biomedcentral.com)
Search the gene expression profiles from curated DataSets in the Gene Expression Omnibus (GEO) repository. (cancerindex.org)
Rather, NAC treatment increased epithelial cell proliferation and promoted the expression of a pro-proliferative gene signature. (pharmaceuticalintelligence.com)
LF82 administration exacerbated fibrosis in DSS-treated mice, revealed by increased colonic collagen deposition and expression of the profibrotic genes Col1a1 , Col3a1 , Fn1 and Vim . (biomedcentral.com)
Pansensitive and panresistant genes to 21 NCCN-recommended drugs with concordant mRNA and protein expression were identified. (cdc.gov)

However, the possibility that transcriptomics can also identify a correlate or surrogate for vaccine inflammation has not been fully explored. (elifesciences.org)
The effects of MIP-1 alpha and TGF beta on the growth of Lin- progenitors were direct and correlate with colony formation in soft agar. (ox.ac.uk)

Anatomy48

Organisms10

Diseases19

Chemicals and Drugs118

Analytical, Diagnostic and Therapeutic Techniques and Equipment23

Phenomena and Processes37

Disciplines and Occupations1

Information Science3

Health Care1

CCL47

Cytokines9

CCL52

CCL23

Cytokine6

Signaling pathway3

MACROPHAGES9

CCR14

CCR22

CCL11

Proinflammatory3

CELLS19

Monocyte2

Proteins2

CXCL101

Inflammatory10

CCR52

NEUTROPHILS3

Molecules2

Protein-coupled2

Chemotactic1

Biomarkers4

MRNA expression1

Interferon1

Activation10

Cysteine2

Tissues2

CCL171

Anti-tumor1

Angiogenesis1

Oxidative stress1

Tumor-associated2

LYMPHOCYTES1

Innate3

Structurally2

Bind2

Target genes1

Chronic inflammation2

Chromosome3

Interleukin1

Expression9

Correlate2