• sperm
  • For example, if a couple is struggling to achieve pregnancy and the male has adequate sperm count, motility, their inability to conceive may be caused by female factor infertility. (docshop.com)
  • Reproductive symptoms in men may include reduced free testosterone (due to the elevation of testosterone-estrogen binding globulin level), diminished libido, erectile dysfunction and (reversible) impaired sperm production with lower mean sperm density, a high incidence of sperm abnormalities, and reduced mobility of the sperm cells. (wikipedia.org)
  • Defective egg or sperm development results in infertility. (wikipedia.org)
  • Defective sperm function remains the single most important cause of human infertility. (wikipedia.org)
  • During the past decade, ICSI has been applied increasingly around the world to alleviate problems of severe male infertility in human patients who either could not be assisted by conventional IVF procedures or could not be accepted for IVF because too few motile and morphologically normal sperm were present in the ejaculate of the male partner. (wikipedia.org)
  • This procedure is most commonly used to overcome male infertility problems, although it may also be used where eggs cannot easily be penetrated by sperm, and occasionally in addition to sperm donation. (wikipedia.org)
  • ASA production are directed against surface antigens on sperm, which can interfere with sperm motility and transport through the female reproductive tract, inhibiting capacitation and acrosome reaction, impaired fertilization, influence on the implantation process, and impaired growth and development of the embryo. (wikipedia.org)
  • Common inherited variants in genes that encode enzymes employed in DNA mismatch repair are associated with increased risk of sperm DNA damage and male infertility. (wikipedia.org)
  • deficiency
  • In addition, CETP expression did not normalize other characteristics of SR-BI deficiency, including female infertility, reticulocytosis, thrombocytopenia, and impaired platelet aggregation. (ahajournals.org)
  • CAH due to 21-hydroxylase deficiency is the most common cause of ambiguous genitalia in genotypically normal female infants (46XX). (wikipedia.org)
  • 17β-Hydroxysteroid dehydrogenase III deficiency is a rare disorder of sexual development, or intersex condition, affecting testosterone biosynthesis by 17β-hydroxysteroid dehydrogenase III (17β-HSD III), which can produce impaired virilization (historically termed male pseudohermaphroditism) of genetically male infants and children and excessive virilization of female adults. (wikipedia.org)
  • as a consequence of impaired male sexual differentiation in 46,XY individuals, as well as: Hypothyroidism Cryptorchidism Infertility Abnormality of metabolism Genetically speaking, 17β-Hydroxysteroid dehydrogenase III deficiency is caused by mutations found in the 17β-HSD III (17BHSD3) gene.17β-HSD III deficiency is an autosomal recessive disorder. (wikipedia.org)
  • Hewitt and Warne state that, children with 17β-hydroxysteroid dehydrogenase III deficiency who are raised as girls often later identify as male, describing a "well known, spontaneous change of gender identity from female to male" that "occurs after the onset of puberty. (wikipedia.org)
  • The term is less commonly used for infertility without hormone deficiency. (wikipedia.org)
  • spermatogenesis
  • The most obvious difference between female oogenesis and male spermatogenesis is the prolonged arrest of oocytes in late stages of prophase I for many years up to several decades. (wikipedia.org)
  • hypogonadism
  • Hypogonadism means diminished functional activity of the gonads-the testes in males or the ovaries in females-that may result in diminished sex hormone biosynthesis. (wikipedia.org)
  • Low androgen (e.g., testosterone) levels are referred to as hypoandrogenism and low estrogen (e.g., estradiol) as hypoestrogenism, and may occur as symptoms of hypogonadism in both sexes, but are generally only diagnosed in males and females respectively. (wikipedia.org)
  • An example of a hypogonadism resulting from the lack of hormone response is androgen insensitivity syndrome, where there are inadequate receptors to bind the testosterone, resulting in a female appearance despite XY chromosomes. (wikipedia.org)
  • Women with hypogonadism do not begin menstruating and it may affect their height and breast development. (wikipedia.org)
  • chromosomes
  • Another important difference between male and female meiosis concerns the frequency of recombination between homologous chromosomes: In the male, almost all chromosome pairs are joined by at least one crossover, while more than 10% of human oocytes contain at least one bivalent without any crossover event. (wikipedia.org)
  • ovulatory
  • It is also indicated for the development of multiple follicles in ovulatory women participating in an assisted reproductive technology (ART) programme, such as in in vitro fertilisation (IVF). (bioportfolio.com)
  • Symptoms
  • There are several diagnostic tests that can be conducted in order to find out if the symptoms are related to the infertility disorder. (petmd.com)
  • In rarer forms of CAH, males are under-masculinized[citation needed] and females generally have no signs or symptoms at birth. (wikipedia.org)
  • Oocytes
  • ICSI is generally performed following a transvaginal oocyte retrieval procedure to extract one to several oocytes from a woman. (wikipedia.org)