• Male Infertility
  • books.google.com - Expertly authored, this text provides a practical, problem-oriented approach devoted exclusively to the surgery of male infertility. (google.com)
  • 20-30% of infertility cases are due to male infertility, 20-35% are due to female infertility, and 25-40% are due to combined problems in both parts. (wikipedia.org)
  • Male infertility is most commonly due to deficiencies in the semen, and semen quality is used as a surrogate measure of male fecundity. (wikipedia.org)
  • Male infertility refers to a male's inability to cause pregnancy in a fertile female. (wikipedia.org)
  • Factors relating to male infertility include: Antisperm antibodies (ASA) have been considered as infertility cause in around 10-30% of infertile couples. (wikipedia.org)
  • Age (see also: Paternal age effect) Genetic defects on the Y chromosome Y chromosome microdeletions Abnormal set of chromosomes Klinefelter syndrome Centriole Neoplasm, e.g. seminoma Idiopathic failure Cryptorchidism Trauma Hydrocele Mumps Malaria Testicular cancer Defects in USP26 in some cases Acrosomal defects affecting egg penetration Idiopathic oligospermia - unexplained sperm deficiencies account for 30% of male infertility. (wikipedia.org)
  • Common inherited variants in genes that encode enzymes employed in DNA mismatch repair are associated with increased risk of sperm DNA damage and male infertility. (wikipedia.org)
  • These findings suggest that DNA damage is an important factor in male infertility. (wikipedia.org)
  • An increasing amount of recent evidence has been recorded documenting abnormal sperm DNA methylation in association with abnormal semen parameters and male infertility. (wikipedia.org)
  • The underlying causative factors in the male infertility can be attributed to environmental toxins, systemic disorders such as, hypothalamic-pituitary disease, testicular cancers and germ-cell aplasia. (wikipedia.org)
  • Genetic factors including aneuploidies and single-gene mutations are also contributed to the male infertility. (wikipedia.org)
  • A large percentage of human male infertility is estimated to be caused by mutations in genes involved in primary or secondary spermatogenesis and sperm quality and function. (wikipedia.org)
  • NR5A1 mutations are associated with male infertility, suggesting the possibility that these mutations cause the infertility. (wikipedia.org)
  • However, it is possible that these mutations individually have no major effect and only contribute to the male infertility by collaboration with other contributors such as environmental factors and other genomics variants. (wikipedia.org)
  • Vice versa, existence of the other alleles could reduce the phenotypic effects of impaired NR5A1 proteins and attenuate the expression of abnormal phenotypes and manifest male infertility solely. (wikipedia.org)
  • Recently, NR5A1 mutations have been related to human male infertility (MIM 613957). (wikipedia.org)
  • These findings substantially increase the number of NR5A1 mutations reported in humans and show that mutations in NR5A1 can be found in patients with a wide range of phenotypic features, ranging from 46,XY sex reversal with primary adrenal failure to male infertility. (wikipedia.org)
  • Subsequently, three missense mutations were identified as associated with and most likely the cause of the male infertility, according to computational analyses. (wikipedia.org)
  • Dr. Rheta Keylor of the Massachusetts Institute for Psychoanalysis stated that, male infertility is an "assault on a man's sense of self revives feelings of competition, castration, and experiences of developmental trauma. (wikipedia.org)
  • In the Psychoanalytic Electronic Publishing archives of the seven primary psychoanalytic journals from 1927 to 2000, not a single article on male infertility appears. (wikipedia.org)
  • for example, in a study exploring the views of fertile individuals towards infertile men and women, Miall (1994) found that male infertility was frequently seen as arising from sexual dysfunction and was thus associated with higher levels of stigma than female infertility. (wikipedia.org)
  • Genetic testing and chromosomal analysis can rule out some other causes of male infertility, such as Kleinfelter's syndrome. (wikipedia.org)
  • Sperm
  • If you or your partner has an infertility problem, you may be able to receive eggs or sperm from a donor to help you conceive. (www.nhs.uk)
  • The most common cause of infertility in men is poor-quality semen, the fluid containing sperm that's ejaculated during sex. (www.nhs.uk)
  • Prognosis in unexplained infertility depends on many factors, but can roughly be estimated by e.g. the Hunault model, which takes into account female age, duration of infertility/subfertility, infertility/subfertility being primary or secondary, percentage of motile sperm and being referred by a general practitioner or gynecologist. (wikipedia.org)
  • Men who acknowledge infertility, articulate the sources of their anxiety, express their loss of confidence in sexual adequacy, deal openly with their wives' disappointment and anger, and consciously redefine their male and marital roles show improved sperm counts and may even be more successful at impregnating their wives. (wikipedia.org)
  • pregnant
  • Medication that stimulates the ovaries isn't recommended for women with unexplained infertility because it hasn't been found to increase their chances of getting pregnant. (www.nhs.uk)
  • Infertility means not being able to get pregnant after a year of trying. (bidmc.org)
  • If a woman gets pregnant but keeps having miscarriages or stillbirths, that is also classified as infertility. (bidmc.org)
  • Infertility means not being able to get pregnant after one year of trying (or six months if a woman is 35 or older). (womenshealth.gov)
  • For most women, infertility is defined as not being able to get pregnant after one year of trying. (womenshealth.gov)
  • Primary infertility refers to the inability to give birth either because of not being able to become pregnant, or carry a child to live birth, which may include miscarriage or a stillborn child. (wikipedia.org)
  • Infertility is the major symptom of TFI and is generally defined as a woman under 35 who has not become pregnant after 12 months without the use of contraception. (wikipedia.org)
  • toxins
  • In broad sense, acquired factors practically include any factor that is not based on a genetic mutation, including any intrauterine exposure to toxins during fetal development, which may present as infertility many years later as an adult. (wikipedia.org)
  • treatments
  • Infertility treatments can be costly and lengthy. (upmc.com)
  • The decision when to apply IVF in endometriosis-associated infertility cases takes into account the age of the patient, the severity of the endometriosis, the presence of other infertility factors, and the results and duration of past treatments. (wikipedia.org)
  • women
  • Top Chef host and model Padma Lakshmi has overcome the shame she felt about her struggle with endometriosis and now supports other women facing the infertility-causing condition. (hollywoodlife.com)
  • For women over 35, infertility may be diagnosed after six months. (womenshealth.gov)
  • It is likely that an effective evaluation for infertility would best include assessment for underlying celiac disease, both in men and women. (wikipedia.org)
  • Infertility affects women from around the world, and the cultural and social stigma surrounding it varies. (wikipedia.org)
  • Also, polymorphisms in folate pathway genes could be one reason for fertility complications in some women with unexplained infertility. (wikipedia.org)
  • According to NICE guidelines, oral ovarian stimulation agents should not be given to women with unexplained infertility. (wikipedia.org)
  • Research suggests that men and women differ in their psychological responses to infertility Samaira Malik, from the Institute of Work, Health, and Organizations at the University of Nottingham, UK, said, "men are in fact equally affected by the unfulfilled desire for a child but are less open about their feelings. (wikipedia.org)
  • Laura A. Peronace, from the School of Psychology at Cardiff University, said, "Male factor infertility is proposed to have such a social stigma that it produces stress, and a culture of secrecy and protectiveness to the extent that women sometimes even take the blame for the couple's childlessness. (wikipedia.org)
  • conceive
  • The time needed to pass (during which the couple tries to conceive) for that couple to be diagnosed with infertility differs between different jurisdictions. (wikipedia.org)
  • Treatment
  • Likewise, nearly 4 million men 25 to 44 have seen a doctor for advice, testing, or treatment for infertility during their lifetime. (womenshealth.gov)
  • While most REI specialists primarily focus on the treatment of infertility, reproductive endocrinologists are trained to also evaluate and treat hormonal dysfunctions in females and males outside infertility. (wikipedia.org)
  • A lot of men believe that there are numerous disincentives to psychological treatment despite its potential benefits, especially for those forms of infertility most linked to psychological and behavioral factors. (wikipedia.org)
  • Lack
  • Existing definitions of infertility lack uniformity, rendering comparisons in prevalence between countries or over time problematic. (wikipedia.org)
  • include
  • Potential methods in unexplained infertility include oral ovarian stimulation agents (such as clomifene citrate, anastrozole or letrozole) as well as intrauterine insemination (IUI), intracervical insemination (ICI) and in vitro fertilization (IVF). (wikipedia.org)