• Because the prevalence of many rheumatologic and infectious diseases is low among persons with uveitis, Lyme serology, antinuclear antibody tests, serum angiotensin-converting enzyme tests, serum lysozyme tests, and tuberculin skin tests can result in false-positive results and are not routinely recommended. (aafp.org)
  • Most forms of uveitis not caused by accidental or surgical trauma are manifestations of infectious or immune-mediated disease. (aafp.org)
  • Dr. Yeh's current research focuses on the application of clinical and laboratory diagnostic modalities for infectious and noninfectious uveitis and the use of emerging therapeutics (systemic and local therapy) for the treatment of uveitis. (emory.edu)
  • Within infectious uveitis, his research has focused on the clinical and scientific implications underlying eye disease in Ebola virus survivors. (emory.edu)
  • They have previously utilized fundus autofluorescence signals and SD-OCT to identify architectural changes in neurosensory retina, retinal pigment epithelium and the choroid in both infectious and noninfectious uveitis. (emory.edu)
  • Based on work in infectious viral uveitis, they have most recently studied Ebola virus disease (EVD) associated uveitis in the United States and West Africa as a result of the recent outbreak of unprecedented magnitude. (emory.edu)
  • Current projects include clinical trials on infectious corneal ulcers, uveitis-related macular edema, and tuberculous uveitis. (ucsf.edu)
  • Dr. Gonzales's interest involves the diagnosis and management of infectious and non-infectious inflammatory conditions of the eyes (uveitis). (ucsf.edu)
  • Uveitis, a significant cause of blindness worldwide, is a term applied to a wide range of conditions that are characterized by intraocular inflammation. (dovepress.com)
  • Whilst common in the developing world, infectious causes account for the minority of uveitis cases presenting to tertiary referral centers in the West. (dovepress.com)
  • Durand ML. Infectious causes of uveitis. (medlineplus.gov)
  • The causes of uveitis can be either noninfectious (most are considered forms of autoimmune uveitis) or infectious. (medscape.com)
  • If left untreated, uveitis can lead to poor visual outcomes, including blindness. (medscape.com)
  • Uveitis causes about 30,000 new cases of blindness each year in the United States. (preventblindness.org)
  • Uveitis is associated with a range of diseases such as multiple sclerosis , Behcet's syndrome, Vogt-Koyanagi-Harada's (VKH) disease, psoriasis , herpes zoster infection, tuberculosis , rheumatoid arthritis , ulcerative colitis , toxoplasmosis , and cytomegalovirus (CMV) retinitis. (lybrate.com)
  • Clinical Infectious Diseases (1) Cytomegalovirus retinitis (CMV retinitis) is a serious viral eye infection of the retina, the light-sensing nerve layer that lines the back of the eye. (vir123.com)
  • Cytomegalovirus infection is a common herpesvirus infection with a wide range of symptoms: from no symptoms to fever and fatigue (resembling infectious mononucleosis) to severe symptoms involving the eyes, brain, or other internal organs. (msdmanuals.com)
  • Infection with cytomegalovirus (CMV) is very common. (msdmanuals.com)
  • Cytomegalovirus (CMV) Infection in Newborns Cytomegalovirus is a common virus that usually causes few or no problems but can cause serious illness in infants who are infected before birth or around the time of birth. (msdmanuals.com)
  • The predictive value of the CD4 + T-cell count for ocular complications in HIV infection has been called into question by reports of CMV retinitis in patients with CD4 + cell counts higher than 200 cells/mL. (medscape.com)
  • In addition, transient blindness has been described in humans recovering from LASV infection ( 3 , 10 ). (cdc.gov)
  • This disease can be infectious or noninfectious, depending on the nature of the infection . (lybrate.com)
  • HHV-4, also known as Epstein-Barr virus (EBV), causes the primary infection infectious mononucleosis , and it is implicated in various diseases, such as African Burkitt lymphoma , other immunoproliferative disorders, and nasopharyngeal carcinoma. (medscape.com)
  • HHV-5, also known as cytomegalovirus (CMV), causes a primary infection of the salivary glands and other tissues, and it is believed to have a chronic form. (medscape.com)
  • Her clinical expertise is the diagnosis and management of patients with infectious and inflammatory eye diseases. (ucsf.edu)
  • He is interested in the epidemiology of major causes of blindness in the developing world, as well as the cost-effectiveness of treatments for these eye diseases. (ucsf.edu)
  • Economic evaluation of combined population-based screening for multiple blindness-causing eye diseases in China: a cost-effectiveness analysis. (ajman.ac.ae)
  • CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
  • certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)
  • While supplements mentioned above may help reduce the symptoms, retinitis itself is not curable. (wikipedia.org)
  • Retrieved December 12, 2017, from https://www.webmd.com/eye-health/retinitis-types-symptoms-treatment#1 Parmeggiani, F. (2011). (wikipedia.org)
  • Most people have no symptoms, but some feel ill and have a fever, and people with a weakened immune system can have serious symptoms, including blindness. (msdmanuals.com)
  • CMV retinitis can arise either upon acute viral introduction to the host or through viral reactivation in the context of immunocompromise. (medscape.com)
  • Conclusions: In the era of HAART, CMV disease as manifested by CMV retinitis and a detectable CMV viral load were associated with an increased risk for mortality, even after adjusting for demographic, treatment, immunologic, and HIV virologic factors. (northwestern.edu)
  • Retinitis is a genotypic disease which entails severe phenotypic representation. (wikipedia.org)
  • In many cases, individuals with retinitis have parents or other relatives unaffected by the disease. (wikipedia.org)
  • Retinitis is the most common manifestation of CMV disease in patients who are HIV positive. (medscape.com)
  • Additionally, devices such as low-vision magnifiers can be used to aid vision in patients with despaired vision due to retinitis. (wikipedia.org)
  • One study including patients with retinitis was conducted by using gene therapy. (wikipedia.org)
  • In most patients, CMV retinitis has an insidious onset that is often asymptomatic, followed by transient visual obscurations ("floaters") and haze, and eventually leading to geographic scotoma and, possibly, complete blindness. (medscape.com)
  • In a study patients had unilateral or bilateral vision loss due to CMV retinitis. (vir123.com)
  • [ 8 ] In addition, infectious uveitides do show sex differences in prevalence, primarily because of behavioral and/or cultural sources. (medscape.com)
  • however, with the advent of highly active antiretroviral therapy (HAART), CMV retinitis is becoming less common in this setting. (medscape.com)
  • Prior clinical research has also focused on intravitreal therapeutics for rapid remission induction of ARN and CMV retinitis and maintenance therapy with oral antiviral agents with high vitreous penetration (i.e. valacyclovir and valganciclovir). (emory.edu)
  • Photokeratitis - keratitis due to intense ultraviolet radiation exposure (e.g. snow blindness or welder 's arc eye. (wikipedia.org)
  • Infectious keratitis can progress rapidly, and generally requires urgent antibacterial, antifungal, or antiviral therapy to eliminate the pathogen. (wikipedia.org)
  • A left-eye wide-field fundus photograph demonstrating a confluent patch of intraretinal whitening, hemorrhage, and vascular attenuation nasal to the optic nerve consistent with CMV retinitis. (medscape.com)
  • Experiencing floaters, flashes, blurred vision and loss of side vision in just one eye may be an early indication of onset of retinitis. (wikipedia.org)
  • Bacterial infections of the lower respiratory tract comprise the majority of infectious complications and have a bimodal temporal distribution. (ersjournals.com)
  • This study investigates the efficacy of dexamethasone (DEX) intravitreal implants as monotherapy for treatment of macular edema in non-infectious intermediate, posterior or panuveitis. (qxmd.com)
  • Current research on retinitis includes studying stem cells, medications, gene therapies, and transplants to help treat/cure this condition. (wikipedia.org)
  • Founded 115 years ago in 1908, Prevent Blindness touches the lives of millions of people each year through public and professional education, advocacy, certified vision screening and training, community and patient service programs and research. (preventblindness.org)
  • Cytomegalovirus (CMV) is a double-stranded DNA virus and is a member of the Herpesviridae family. (medscape.com)
  • While such findings may argue against the protective effect of an increased CD4 + cell count, the possibility that the CMV retinitis preceded the recovery of CD4 + cell count was not ruled out. (medscape.com)
  • Specifically, they have previously assessed the utility of qualitative and quantitative PCR, as well as ganciclovir-resistance testing in the management of CMV retinitis. (emory.edu)
  • Gram-negative pathogens, in particular Pseudomonas aeruginosa , are most frequently isolated in association with both early and late infectious events 1 , 2 . (ersjournals.com)