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  • diseases
  • These conditions are listed below: Perinatal (during birth) cerebral injury Kernicterus Cerebrovascular diseases Drug induced Central nervous system tumor Peripheral or central trauma Infectious or post infectious encephalopathies Toxins Metabolic Paraneoplastic syndromes Central pontine myelinolysis Secondary spasmodic torticollis is diagnosed when any of the following are present: history of exogenous insult or exposure, neurological abnormalities other than dystonia, abnormalities on brain imaging, particularly in the basal ganglia. (wikipedia.org)
  • Abnormalities include hereditary and acquired cell membrane disorders (eg, spherocytosis), disorders of RBC metabolism (eg, G6PD deficiency ), and hemoglobinopathies (eg, sickle cell diseases , thalassemias ). (merckmanuals.com)
  • Many infectious diseases have a risk of vertical transmission to the fetus. (wikipedia.org)
  • SNHL is at least partially preventable by avoiding environmental noise, ototoxic chemicals and drugs, and head trauma, and treating or inoculating against certain triggering diseases and conditions like meningitis. (wikipedia.org)
  • symptoms
  • Symptoms caused chemically by drugs such as cannabis, magic mushrooms, or cocaine tend to dissipate after the chemical compound has been excreted from the body. (wikipedia.org)
  • The central harm of cancer screening is overdiagnosis - the detection of abnormalities that meet the pathologic definition of cancer (under the microscope) but will never progress to cause symptoms or death during a patient's ordinarily expected lifetime. (wikipedia.org)
  • In other words, there are cellular abnormalities that meet the pathologic definition of cancer but never grow to cause symptoms - alternatively, they may grow and then regress. (wikipedia.org)
  • cause
  • However, we must also consider drugs as a chronic cause, especially if given intermittently. (clinicaladvisor.com)
  • Infectious organisms may cause hemolytic anemia through the direct action of toxins (eg, from Clostridium perfringens , alpha- or beta-hemolytic streptococci, meningococci), by invasion and destruction of the RBC by the organism (eg, Plasmodium sp, Bartonella sp), or by antibody production (Epstein-Barr virus, mycoplasma). (merckmanuals.com)
  • Quantitative and functional abnormalities of certain RBC membrane proteins (alpha- and beta-spectrin, protein 4.1, F-actin, ankyrin) cause hemolytic anemias. (merckmanuals.com)
  • A more extensive list follows: Causes of photophobia relating directly to the eye itself include: Achromatopsia Aniridia Anticholinergic drugs may cause photophobia by paralyzing the iris sphincter muscle. (wikipedia.org)
  • Exposure to a very loud noise such as a bomb blast can cause noise-induced hearing loss. (wikipedia.org)
  • They may also induce the expression of other cytokines in the brain that cause sickness behavior. (wikipedia.org)
  • toxicity
  • High dose cyclophosphamide (CY), higher dose of TBI (total body irradiation), busulfan (Bu) (by inducing oxidative stress rather than direct toxicity), gemtuzumab ozogamicin, and busulfan and melphalan based regimens. (neurologyadvisor.com)
  • bone
  • Matrix metalloproteinase 2 may be a candidate gene for bisphosphonate-associated osteonecrosis of the jaws, since it is the only gene known to be associated with both bone abnormalities and atrial fibrillation, another side effect of bisphosphonates. (wikipedia.org)
  • Owing to prolonged embedding of bisphosphonate drugs in the bone tissues, the risk for BRONJ is high even after stopping the administration of the medication for several years. (wikipedia.org)
  • Epilepsy
  • Macropsia has a wide range of causes, from prescription and illicit drugs, to migraines and (rarely) complex partial epilepsy, and to different retinal conditions, such as epiretinal membrane. (wikipedia.org)
  • treatment
  • Eflornithine is not effective in the treatment of Trypanosoma brucei rhodesiense due to the parasite's low sensitivity to the drug. (wikipedia.org)
  • Efficacy
  • This information will be used to design similar future studies for the initial assessment of the efficacy of novel antimalarial drugs in development. (clinicaltrials.gov)
  • Another randomized control trial in Uganda compared the efficacy of various combinations of these drugs and found that the nifurtimox-eflornithine combination was the most promising first-line theory regimen. (wikipedia.org)
  • Mechanical
  • In individuals who require an artificial heart valve, consideration must be made for deterioration of the valve over time (for bioprosthetic valves) versus the risks of blood clotting in pregnancy with mechanical valves with the resultant need of drugs in pregnancy in the form of anticoagulation. (wikipedia.org)
  • typically
  • Typically, drugs that inhibit cell growth are considered candidates for cancer therapy, so eflornithine was naturally believed to have potential utility as an anti-cancer agent. (wikipedia.org)
  • primary
  • Although no lesions are present in the basal ganglia in primary spasmodic torticollis, fMRI and PET studies have shown abnormalities of the basal ganglia and hyper activation of the cortical areas. (wikipedia.org)
  • Primary spasmodic torticollis is defined as having no other abnormality other than dystonic movement and occasional tremor in the neck. (wikipedia.org)
  • Type
  • The most common type of HIV induced cardiomyopathy is dilated cardiomyopathy also known as eccentric ventricular hypertrophy which leads to impaired contraction of the ventricles due to volume overload. (wikipedia.org)
  • cases
  • Although the total United States prescriptions for oral bisphosphonates exceeded 30 million in 2006, less than 10% of BON cases were associated with patients taking oral bisphosphonate drugs. (wikipedia.org)
  • include
  • Other treatments modulate the adverse immune response to allergens and include antihistamines, steroids, ciclosporin and immunotherapy (a process in which allergens are injected to try to induce tolerance). (wikipedia.org)
  • regimens
  • This is an enabling study using registered antimalarial drugs as reference treatments (one slow acting and one fast acting), aimed to inform trial design, endpoints and testing regimens for assessing new candidate antimalarial drugs in development. (clinicaltrials.gov)
  • common
  • The most common kind of sensorineural hearing loss is age-related (presbycusis), followed by noise-induced hearing loss (NIHL). (wikipedia.org)
  • itself
  • Pregnancy itself is a factor of hypercoagulability (pregnancy-induced hypercoagulability), as a physiologically adaptive mechanism to prevent post partum bleeding. (wikipedia.org)
  • patients
  • Although we could not draw any conclusions regarding the development of small bowel abnormalities in HIV-infected patients, our results may provide some insight regarding the pathogenesis of HIV enteropathy. (hindawi.com)
  • blood
  • Two weeks after the start of the study drug, blood will be taken to check for potential toxic side effects. (clinicaltrials.gov)
  • A clotting abnormality and low platelet concentration in the blood should be immediately corrected if possible. (wikipedia.org)
  • agents
  • HIV-1 could possibly have a direct effect on the endothelium as has been suggested for other infectious agents such as chlamydia, herpes simplex, and cytomegalovirus. (clinicaltrials.gov)
  • administration
  • In response to the growing base of literature on this association, the United States Food and Drug Administration issued a broad drug class warning of this complication for all bisphosphonates in 2005. (wikipedia.org)
  • Acute
  • The role of autoimmunities and allergies is manifested in postinfluenzal myocarditis, in which the acute infectious disease (influenza) passes but the myocarditis caused by it persists for many months. (thefreedictionary.com)
  • viral
  • Forty-five percent of patients (n=36) had received more than one course of prior therapy, and 90 percent (n=72) had at least one viral mutation associated with HCV NS3, NS5A or NS5B drug resistance. (blogspot.com)
  • Importantly, Sovaldi has now demonstrated efficacy among genotype 1 HCV infected patients who failed prior treatment with three or four drug regimens and have developed viral resistance to some of the components of those regimens. (blogspot.com)
  • liver
  • Patients with AIDS Clinical Trials Group (ACTG) grade IV liver function test abnormalities, grade III or higher renal insufficiency, grade III or higher leucopenia, or dementia thought to impair adherence were excluded. (biomedcentral.com)
  • Reduced HCV antibody production, drug interactions, other causes of liver disease, differing epidemiologic characteristics and natural history complicate the management of HCV/HIV patients. (wikipedia.org)
  • characteristic
  • The extent to which the findings of increased mortality in observational studies may be attributed to the antipsychotic drug as opposed to some characteristic(s) of the patients is not clear. (nih.gov)
  • diagnosis
  • Although sepsis has diverged from SIRS criteria for diagnosis and management in recent years, focusing more on infectious etiologies, the pathophysiologic processes present in sepsis and noninfectious SIRS are remarkably similar, making a discussion of SIRS in critical illness appropriate. (medscape.com)
  • The phenomenon is so common when DEC is used that this drug is the basis of a skin patch test used to confirm that diagnosis. (wikipedia.org)
  • widely
  • Despite Pfizer withdrawing its own recommendation for Lyrica for many forms of neuropathy as long ago as 2013 and despite the mounting evidence of the harm it can do, it remains one of the most widely prescribed mainstream drugs for nerve pain across the whole world. (blogspot.com)
  • symptoms
  • Symptoms caused chemically by drugs such as cannabis, magic mushrooms, or cocaine tend to dissipate after the chemical compound has been excreted from the body. (wikipedia.org)
  • brain
  • Once the prion is transmitted, the defective proteins invade the brain and induce other prion protein molecules to misfold in a self-sustaining feedback loop. (wikipedia.org)
  • treatment
  • Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. (nih.gov)
  • Only one HDAC inhibitor, suberonylanilide hydroxamic acid (SAHA), marketed as Zolinza (vorinostat) has been approved by US Foods and Drugs Administration (FDA) for the treatment of cutaneous T-cell lymphoma (http://www.cancer.gov/cancertopics/druginfo/fdavorinostat) . (docplayer.net)
  • pregnant
  • For the study, information was collected in seven countries from 164 women who took pregabalin during a pregnancy and 656 pregnant women who were not taking any anti-seizure drugs. (blogspot.com)
  • The study was to prove efficacy in reducing HIV transmission from pregnant mothers to their newborns, but researchers also "forgot" to include a control group of mothers that did not receive the drug. (newmediaexplorer.org)
  • Apparently the US health authorities thought so, because the application by Boeringer Ingelheim to use their drug on pregnant mothers in the US was never approved. (newmediaexplorer.org)
  • risk
  • Analyses of seventeen placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 to 1.7 times the risk of death in placebo-treated patients. (nih.gov)
  • Smoking can increase the risk in women a few different ways, which can be by direct and indirect methods of inducing cervical cancer. (wikipedia.org)
  • role
  • The first of these were local apothecaries that expanded from their traditional role distributing botanical drugs such as morphine and quinine to wholesale manufacture in the mid 1800s. (wikipedia.org)
  • particularly
  • Rational drug discovery from plants started particularly with the isolation of morphine, analgesic and sleep-inducing agent from opium, by the German apothecary assistant Friedrich Sertürner, who named the compound after the Greek god of dreams, Morpheus. (wikipedia.org)
  • patients
  • Over the course of a typical 10-week controlled trial, the rate of death in drug-treated patients was about 4.5%, compared to a rate of about 2.6% in the placebo group. (nih.gov)
  • Patients meet the criteria for septic shock if they have persistent hypotension and perfusion abnormalities despite adequate fluid resuscitation. (medscape.com)
  • In the first trial, approximately the same number of patients from each group withdrew due to laboratory abnormalities or adverse events. (wikipedia.org)
  • Group
  • The doses were modified more frequently in the peginterferon group due to lab abnormalities (7% vs 20%) or adverse events (7% vs 16%) (p=0.004). (wikipedia.org)
  • present
  • Although no lesions are present in the basal ganglia in primary spasmodic torticollis, fMRI and PET studies have shown abnormalities of the basal ganglia and hyper activation of the cortical areas. (wikipedia.org)
  • known
  • Lyme disease, also known as Lyme borreliosis, is an infectious disease caused by bacteria of the Borrelia type which is spread by ticks. (wikipedia.org)
  • cause
  • AZT, Nevirapine: Do Anti-Retroviral Drugs Cause AIDS? (newmediaexplorer.org)
  • What causes 6 things your hiccups are trying to tell you can heartburn cause the Drugs. (findmedr.com)
  • A more extensive list follows: Causes of photophobia relating directly to the eye itself include: Achromatopsia Aniridia Anticholinergic drugs may cause photophobia by paralyzing the iris sphincter muscle. (wikipedia.org)
  • Infectious prions are misfolded proteins that can cause normally folded proteins to become misfolded. (wikipedia.org)
  • cell
  • The underlying mechanism appears to be mediated by SphK1 induced upregulation of select gene transcription programs such as that of CBP/p300 and PCAF, two histone acetyl transferases (HAT), and the down regulation of cell cycle dependent kinase inhibitor genes such as p27kip1 and p21cip1. (docplayer.net)
  • blood
  • Sepsis-induced hypotension is defined as "the presence of a systolic blood pressure of less than 90 mm Hg or a reduction of more than 40 mm Hg from baseline in the absence of other causes of hypotension. (medscape.com)
  • A clotting abnormality and low platelet concentration in the blood should be immediately corrected if possible. (wikipedia.org)
  • type
  • HIV, a new type of "retrovirus" was announced by Robert Gallo at a press conference , and we needed an immediate killer drug. (newmediaexplorer.org)
  • Using a multi-walled carbon nanotubes induced peritoneal mesothelioma mouse model, we showed that the SphK12/2 null mice exhibited significantly less inflammation and granulamatous nodules compared to their wild type counterparts. (docplayer.net)
  • birth
  • You may wonder what an article about birth defects has to do with neuropathy but the common link is the drug pregabalin (Lyrica). (blogspot.com)
  • Pregnancies of the women who took pregabalin during the first trimester of pregnancy were three times more likely to result in major birth defects than those of the women who did not take anti-seizure drugs. (blogspot.com)
  • Seven of the 116 pregnancies in women taking anti-seizure drugs, or 6 percent, had major birth defects, compared to 12 of 580 pregnancies, or 2 percent, in women who did not take the drug. (blogspot.com)
  • Winterfeld said, "Pregabalin should be prescribed for women of child-bearing age only after making sure that the benefits of the drug outweigh the risks and after counseling them about using effective birth control. (blogspot.com)
  • food
  • The only US Food and Drug Administration (FDA)-approved antibiotics to treat vancomycin-resistant E. faecium are quinupristin-dalfopristin (Q/D) and linezolid. (clinicalpainadvisor.com)
  • women
  • The women taking pregabalin were six times more likely to have a pregnancy with a major defect in the central nervous system than women who were not taking the drug, with four CNS defects out of 125 pregnancies, or 3.2 percent, compared to three CNS defects out of 570 pregnancies, or 0.5 percent. (blogspot.com)
  • The women in the study stopped taking the drug at an average of six weeks into their pregnancies. (blogspot.com)
  • Of the women taking pregabalin, 22, or 13 percent, were also taking another anti-seizure drug. (blogspot.com)
  • A tragedy of global proportions is unfolding over a toxic anti-HIV drug given to hundreds of thousands of women and babies in the developing world in the belief that it can help prevent the spread of Aids. (newmediaexplorer.org)