Together they generated the DBA (Dilute, Brown and non-Agouti) inbred mouse strain and initiated the systematic generation of inbred strains. (wikipedia.org)
The laboratory is also the world's source for more than 8,000 strains of genetically defined mice and is home of the Mouse Genome Informatics database. (wikipedia.org)
There are hundreds of established inbred, outbred, and transgenic strains. (wikipedia.org)
Differences in hepatic fibrosis and granuloma size in several strains of mice infected with Schistosoma japonicum. (rsbmt.org.br)
PCR tests for the genetic background of inbred and wild-derived strains by using microsatellite or single nucleotide polymorphism (SNP) markers. (riken.jp)
Adult rats (14 stocks and strains) and mice (more than 40 stocks and strains) were euthanized using a 50% volume per minute displacement rate of carbon dioxide for 2 min. (bvsalud.org)
SCID2
In addition, LDV-induced poliomyelitis has not been reported in SCID or ICR mice. (elsevierpure.com)
Here we describe the occurrence of poliomyelitis in ICR-SCID mice resulting from injection of LDV-contaminated basement membrane matrix. (elsevierpure.com)
In recent years green fluorescent protein (GFP) from the bioluminescent jellyfish Aequoria Victoria has gained popularity in mouse transgenic and gene targeting regimes [ 1 ]. (biomedcentral.com)
The ECFP and EYFP-expressing transgenic ES cells and mice that we have generated provide sources of cells and tissues for combinatorial, double-tagged recombination experiments, chimeras or transplantations. (biomedcentral.com)
Genes2
The laboratory mouse genome has been sequenced and many mouse genes have human homologues. (wikipedia.org)
Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans. (ouhsc.edu)
Strain2
A monoclonal antibody (MAb) against EXA prevented the death of the mice if it was given simultaneously with, or 2 h before, infection with strain PA103. (nih.gov)
Little and Castle collaborated closely with Abbie Lathrop who was a breeder of fancy mice and rats which she marketed to rodent hobbyists and keepers of exotic pets, and later began selling in large numbers to scientific researchers. (wikipedia.org)
However, relatively little information is available on humane aspects of anesthesia and euthanasia in neonatal mice and rats. (bvsalud.org)
The study demonstrates that CO may be a potential alternative for preweanling mice and rats at PND6 or older but is not appropriate for neonates at PND5 or younger. (bvsalud.org)
The current study was designed based on existing literature regarding minimal exposure times for preweanling rats and mice euthanized with carbon dioxide. (bvsalud.org)
The study evaluated the minimal time that adult rats and mice must remain in 100% carbon dioxide for death to be irreversible on removal. (bvsalud.org)
The experiment on 71 non-inbred white pregnant rats, 316 fetuses and placentas, 323 first progeny in experimental chronic impairment of uteroplacental circulation in females with pregnancy in the ploid period has found that decimetric waves (DW) in a weak heat dose (40 mW/cm2) prevents hypotrophy and disorders of fetal and placental development. (maxwellmagneticmeds.co.za)
Murine1
RT-PCR yielded murine leukemia virus in spinal cords of all mice tested, regardless of clinical presentation or neuropathology. (elsevierpure.com)
Genetic2
Genetic-linked variation in susceptibility of mice to Schistosomiasis mansoni . (rsbmt.org.br)
The ease of manipulating its genome has helped establish the mouse as the premier model organism for mammalian genetic studies. (biomedcentral.com)
Mammals1
Mice are mammals of the clade (a group consisting of an ancestor and all its descendants) Euarchontoglires, which means they are amongst the closest non-primate relatives of humans along with lagomorphs, treeshrews, and flying lemurs. (wikipedia.org)
Genetically1
Genetically manipulated mice, often incorporating gene-based reporters, are frequently being used to model and understand mammalian development and disease processes. (biomedcentral.com)
Diseases2
the disease course of ebo-r in macaques was very similar to human disease and to experimental diseases in macaques following ebo-zaire and ebo-sudan infections. (liverpool.ac.uk)
This study was performed to produce reference data for eye toxicity tests and to investigate the ophthalmic diseases of 408 ICR mice and 119 BALB/c mice, which are commonly used as subjects in toxicity tests. (go.jp)
MeSH1
Mice, Inbred DBA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
Mutant1
P. aeruginosa PA103, which produced EXA, was 20 times more virulent for normal mice than was its EXA-deficient mutant, PA103-29. (nih.gov)
Laboratory5
The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. (wikipedia.org)
Laboratory mice are usually of the species Mus musculus. (wikipedia.org)
Other mouse species sometimes used in laboratory research include two American species, the white-footed mouse (Peromyscus leucopus) and the North American deer mouse (Peromyscus maniculatus). (wikipedia.org)
In the early part of the 20th century, Harvard undergraduate Clarence Cook Little was conducting studies on mouse genetics in the laboratory of William Ernest Castle. (wikipedia.org)
The Jackson Laboratory in Bar Harbor, Maine is currently one of the world's largest suppliers of laboratory mice, at around 3 million mice a year. (wikipedia.org)
Vitro2
The effects of exotoxin A (EXA) from Pseudomonas aeruginosa on polymorphonuclear leucocytes (PMNLs) were studied in a mouse model and in vitro. (nih.gov)
Effects of endogenous D-alanine synthesis and autoinhibition of Bacillus anthracis germination on in vitro and in vivo infections. (ouhsc.edu)
Bacillus1
In this study, we used mice lacking the SR-A (SRKO) to investigate the role of SR-A in acquired immunity using a viable bacillus Calmette Guérin (BCG) infection model. (ox.ac.uk)
Pathogenicity1
Studies performed in mice indicated that the peripheral pathogenicity of LBV had been underestimated in previous studies. (cdc.gov)
Incidence2
despite this, few studies have examined the incidence, prevalence, or exposure-associated rates of infection or have considered infection-specific interventions recommended to maintain worker safety. (liverpool.ac.uk)
BALB/c mice, 31.9%) and the incidence gradually decreased with age. (go.jp)
Pups1
This study was designed to assess the effectiveness of carbon monoxide (CO) as an alternative euthanasia agent for mouse and rat pups on postnatal days (PND) 0 to 12. (bvsalud.org)
Viable2
To this end, we have established lines of ES cells together with viable and fertile mice having widespread expression of either the ECFP or EYFP GFP-variant reporters. (biomedcentral.com)
We therefore wished to investigate the feasibility of non-invasive multiple reporter imaging in mice, and as a first step we wanted to ascertain whether we could establish viable and fertile mice with widespread expression of GFP variant reporters. (biomedcentral.com)
Investigate1
Mice have been used in biomedical research since the 17th century (from May 30, 1678) when William Harvey used them for his studies on reproduction and blood circulation and Robert Hooke used them to investigate the biological consequences of an increase in air pressure. (wikipedia.org)
Animals2
In 1902 Lucien Cuénot published the results of his experiments using mice which showed that Mendel's laws of inheritance were also valid for animals - results that were soon confirmed and extended to other species. (wikipedia.org)
Inbred plants, like inbred animals, don't fare well, at least over time-a phenomenon that's now known as inbreeding depression. (ussromantics.com)
Contrast2
In contrast, members of phylogroup II are believed to be pathogenic in mice only when introduced by the intracerebral (i.c.) route ( 5 ). (cdc.gov)
In contrast, FIPV RG14620 infections causes a chronic and incredibly fatal pleuritis/peritonitis often. (conferencedequebec.org)
Granuloma1
After BCG infection, SRKO mice are able to recruit Mphi to sites of granuloma formation where they become activated and restrict BCG replication. (ox.ac.uk)
Protein1
We have previously demonstrated the utility and developmental neutrality of enhanced green fluorescent protein (EGFP) in embryonic stem (ES) cells and mice [ 2 ]. (biomedcentral.com)
Supplemental1
Please confirm the list and explanations of performed, not-performed and supplemental QC tests for mouse resources in each distribution format. (riken.jp)
Humans2
Mice belong to the Euarchontoglires clade, which includes humans. (wikipedia.org)
This close relationship, the associated high homology with humans, their ease of maintenance and handling, and their high reproduction rate, make mice particularly suitable models for human-oriented research. (wikipedia.org)
General1
As a general rule, inbred mice tend to have longer gestation periods and smaller litters than outbred and hybrid mice. (wikipedia.org)
Study2
During the 18th century Joseph Priestley and Antoine Lavoisier both used mice to study respiration. (wikipedia.org)
In this study, the effect of TWK10 on the progression of age-related impairments was investigated in mice. (frontiersin.org)
Model2
The mouse has since been used extensively as a model organism and is associated with many important biological discoveries of the 20th and 21st Centuries. (wikipedia.org)
Retinal ganglion cell protection by 17-beta-estradiol in a mouse model of inherited glaucoma. (ouhsc.edu)
Found1
We found that TWK10 not only enhanced muscle strength in young mice, but also prevented the aging-related loss of muscle strength in aged mice, which was accompanied by elevated muscle glycogen levels. (frontiersin.org)
Tests2
PCR tests of cTG and cKO mice to examine the fragment length between loxPs or FRTs with primers designed based on information provided by the Depositor. (riken.jp)
Microbial QC tests are performed quarterly by using dirty bedding sentinel mice housed in each rack. (riken.jp)
Year1
This graph shows the total number of publications written about "Mice, Inbred DBA" by people in this website by year, and whether "Mice, Inbred DBA" was a major or minor topic of these publications. (ouhsc.edu)
Results2
Collectively, these results not only confirm that EXA is toxic in vivo, but also suggest that this toxin accelerates the growth of virulent P. aeruginosa in mice. (nih.gov)
Deposited mice are housed separately based on the microbial test results at deposition, and then, all the mice are cleaned-up by a rederivation procedure. (riken.jp)
Levels1
TWK10-treated mice also experienced an increase in short-chain fatty acid (SCFA)-producing bacteria and higher overall levels of gut SCFA. (frontiersin.org)
Virus3
no other clinical entity has attached more attention now-a-day than those precipitated by the infection with a hemorrhagic fever virus. (liverpool.ac.uk)
One phylogroup consists of Mokola virus and LBV (group II), while all other genotypes are in group I. Members of phylogroup I are reported to be pathogenic for mice when introduced intramuscularly and intracerebrally. (cdc.gov)
The arterivirus lactate dehydrogenase-elevating virus (LDV) causes life-long viremia in mice. (elsevierpure.com)