• ethylene
  • citation needed] D - Diabetic ketoacidosis U - Uremia M - Methanol P - Paraldehyde S - Salicylates A - Alcoholic ketoacidosis L - Lactic acidosis E - Ethylene Glycol The mnemonic for the [rare, in comparison] toxins is ACE GIFTs: Aspirin, Cyanide, Ethanolic ketosis, Glycols [ ethylene and propylene ], Isoniazid, Ferrous iron, Toluene. (wikipedia.org)
  • patients
  • In these patients, overdose with isoniazid should be suspected. (medscape.com)
  • When it happens, isoniazid-induced liver toxicity has been shown to occur in 50% of patients within the first 2 months of therapy. (wikipedia.org)
  • However, Candace Baker, Jerome Reich and Richard Johnson describe a series of six patients with MAC infection of the right middle lobe or left lingula who did not have any predisposing lung disorders. (wikipedia.org)
  • Since the six patients in their retrospective case series were older females, Reich and Johnson and Baker proposed that patients without a vigorous cough may develop right middle lobe or left lingular infection with MAC. (wikipedia.org)
  • Liver toxicity occurs in up to 5% of patients and follows a pattern similar to isoniazid, usually arising in the first 1 to 3 months of therapy, but can occur even after more than 6 months of therapy. (wikipedia.org)
  • commonly
  • Efavirenz (EFV) is an anti-HIV medicine that is commonly used to treat HIV infection in adults and children older than 3 years of age. (clinicaltrials.gov)
  • Bronchiectasis, the bronchial condition which causes unnatural enlargement of the bronchial tubes, is commonly found with MAI infection. (wikipedia.org)
  • pregnancy
  • Vitamin B6 is used to prevent isoniazid-induced B6 deficiency and neuropathy in people with a risk factor, such as pregnancy, lactation, HIV infection, alcoholism, diabetes, kidney failure, or malnutrition. (wikipedia.org)
  • months
  • Isoniazid (INH) daily for 9 months (240 to 270 total doses). (clinicaltrials.gov)
  • Eligible individuals were randomly allocated (1:1) to receive 6 months' open-label isoniazid followed by 30 months' masked placebo (control group) or 6 months' open-label isoniazid followed by 30 months' masked isoniazid (continued isoniazid group) on the basis of a computer-generated randomisation list with permuted blocks of ten at each clinic. (www.gov.uk)
  • liver
  • Levels of liver enzymes in the bloodstream should be frequently checked in daily alcohol drinkers, pregnant women, IV drug users, people over 35, and those who have chronic liver disease, severe kidney dysfunction, peripheral neuropathy, or HIV infection since they are more likely to develop hepatitis from INH. (wikipedia.org)
  • Isoniazid is thought to induce a liver enzyme which causes a larger amount of acetaminophen to be metabolized to a toxic form. (wikipedia.org)
  • 140/90 mmHg), or arteriosclerosis Liver pathologies Infection (Hepatitis C) Hemochromatosis Gastroparesis Polycystic ovary syndrome (PCOS) Hypercortisolism (e.g. (wikipedia.org)
  • Severe
  • Severe adverse events and death were much the same in the control and continued isoniazid groups. (www.gov.uk)
  • Isoniazid has a boxed warning for severe and sometimes fatal hepatitis, which is age-dependent at a rate of 0.3% in people 21 to 35 years old and over 2% in those over age 50. (wikipedia.org)
  • Chronic
  • It can cause post-traumatic wound infections especially those following open fractures and with associated osteomyelitis and chronic lipoid pneumonia. (wikipedia.org)
  • together
  • It boosts levels of isoniazid when taken together and can lead to increased rates of peripheral neuropathy and hepatotoxicity. (wikipedia.org)
  • cause
  • MAC infections can cause fevers, diarrhea, malabsorption, as well as loss of appetite and weight loss, and can disseminate to the bone marrow. (wikipedia.org)
  • MAC bacteria are common in the environment and cause infection when inhaled or swallowed. (wikipedia.org)