• cells
  • In vitro experiments and studies in mice showed that CTLs are able to specifically target cancerous cells and destroy them by inducing apoptosis ( 12 , 13 , 17 ). (frontiersin.org)
  • system
  • Dendritic cell (DC)-based immunotherapy employs the patients' immune system to fight neoplastic lesions spread over the entire body. (frontiersin.org)
  • The ability of the immune system to fight tumors was first described by William B. Coley, who in the nineteenth century observed cancer regression in patients suffering from inoperable sarcoma after injecting bacterial toxins into neoplastic lesions ( 11 ). (frontiersin.org)