• ibuprofen
  • ibuprofen vs continuous IV indomethacin has different side effects, eg. (bioportfolio.com)
  • Despite the fact that ibuprofen appears to minimize the renal side effects seen following bolus indomethacin, other concerns regarding both short and long-term safety remain. (bioportfolio.com)
  • Ibuprofen therapy has not, to date, been compared with indomethacin administered by continuous infusion. (bioportfolio.com)
  • Hence, in the current study we attempted to determine whether continuous indomethacin administration could potentially offer the same advantages as ibuprofen in treating PDA, specifically in terms of mitigation of renal side effects. (bioportfolio.com)
  • As secondary objectives we intend to determine whether a decrease in BNP levels would be an equally reliable indicator of therapeutic efficacy in infants treated with ibuprofen as with indomethacin.In addition we will look at comparative effects on other vascular beds which might mediate long term side effects described above. (bioportfolio.com)
  • The purpose of the study is to determine the safety and efficacy of ibuprofen, compared with indomethacin, in the treatment for the closure of the patent ductus arteriosus in premature bab. (bioportfolio.com)
  • We hypothesize that feeding preterm infants while they receive indomethacin or ibuprofen therapy for treatment of a patent ductus arteriosus will decrease the incidence of feeding intolera. (bioportfolio.com)
  • Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis. (bioportfolio.com)
  • rectal
  • Data from a multicenter, randomized, placebo-controlled, double-blind trial in patients at elevated risk for post-ERCP pancreatitis supports the use of rectal indomethacin administered immediately after the procedure to prevent post-ERCP pancreatitis [Elmunzer . (drugs.com)
  • headache
  • Paradoxically yet uncommonly, indometacin can cause headache (10 to 20%), sometimes with vertigo and dizziness, hearing loss, tinnitus, blurred vision (with or without retinal damage). (wikipedia.org)
  • formulation
  • In accordance with the present invention, the controlled release formulation contains coated pellets of indomethacin of only one type. (google.com.au)
  • This invention relates to a novel oral pharmaceutical formulation of indomethacin having controlled release properties. (google.com.au)
  • The formulation provides an immediate release indomethacin for elevating blood levels to pharmacologically effective levels and sustained release indomethacin for maintaining those levels. (google.com.au)
  • renal
  • Thus, if we were to be able to eliminate the differential renal effects, indomethacin would remain, for many, the therapy of choice for the premature neonate with a persistent PDA. (bioportfolio.com)
  • effective
  • The sustained release indomethacin is gradually released over time to maintain the blood levels at effective concentrations for long periods of time. (google.com.au)
  • healthcare
  • When you are taking indomethacin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. (drugs.com)
  • treatment
  • In one study after one week of treatment with orally administered indomethacin, this effect on basal cerebral blood flow had disappeared. (nih.gov)
  • therapy
  • Presents a case study of a young woman with glomerulonephritis who was receiving indomethacin therapy and was diagnosed with hyporeninemic hypoaldosteronism. (ebscohost.com)