• toxic
  • Common causes of chronic neuroinflammation include: Toxic metabolites Autoimmunity Aging Microbes Viruses Traumatic brain injury Spinal cord injury Air pollution Passive smoke Microglia are recognized as the innate immune cells of the central nervous system. (wikipedia.org)
  • births
  • Data collected by the National Center for Health Statistics, part of the Centers for Disease Control and Prevention, show that in the U.S. the number of births to men aged 40 to 49 nearly tripled between 1980 and 2004, rising from 120,702 to 328,465. (cartercenter.org)
  • younger
  • They found that children born to fathers 40 or older had nearly a sixfold increase in the risk of autism as compared with kids whose fathers were younger than 30. (cartercenter.org)
  • Workers in this age group are more likely to suffer from lower back pain that may be worsened by work conditions that normally do not affect a younger worker. (wikipedia.org)
  • cognitive
  • These data indicate that human NGF can reverse age-related cognitive impairments in old rats. (jneurosci.org)
  • Biomedical theories hold that one can age successfully by caring for physical health and minimizing loss in function, whereas psychosocial theories posit that capitalizing upon social and cognitive resources, such as a positive attitude or social support from neighbors and friends, is key to aging successfully. (wikipedia.org)
  • veins
  • This valvular incompetence combined with persistent venous obstruction from thrombus increases the pressure in veins and capillaries. (wikipedia.org)
  • Increased weight can put more stress and pressure on leg veins, and can predispose patients to developing PTS. (wikipedia.org)
  • Venous
  • The three factors of Virchow's triad-venous stasis, hypercoagulability, and changes in the endothelial blood vessel lining (such as physical damage or endothelial activation)-contribute to DVT and are used to explain its formation. (wikipedia.org)
  • clinical
  • Clinical trials have suggested that eldecalcitol, a vitamin D analog, has strong effects to reduce calcium reabsorption into the body from bones, therefore increasing bone mineral density, and to increase calcium absorption in intestines. (wikipedia.org)
  • Univariate and multivariate analysis were performed to determine the clinical factors associated with LTBI. (ersjournals.com)
  • typically
  • The current cosmological estimates of the age of the universe, in contrast, are typically of the order of 14 billion years. (wikipedia.org)
  • Stage theories typically focus on "age-appropriate" developmental tasks to be achieved at each stage. (wikipedia.org)
  • The underlying mechanism typically involves some combination of decreased blood flow rate, increased tendency to clot, and injury to the blood vessel wall. (wikipedia.org)
  • induce
  • Common cytokines produced in response to brain injury include: interleukin-6 (IL-6), which is produced during astrogliosis, and interleukin-1 beta (IL-1β) and tumor necrosis factor alpha (TNF-α), which can induce neuronal cytotoxicity. (wikipedia.org)
  • Brain
  • The researchers said that advanced paternal age, as they call it, has also been linked to an increased risk of birth defects, cleft lip and palate, water on the brain, dwarfism, miscarriage and "decreased intellectual capacity. (cartercenter.org)
  • After injury and sustained release of inflammatory factors such as chemokines, the blood-brain barrier may be compromised, becoming permeable to circulating blood components and peripheral immune cells. (wikipedia.org)
  • psychological
  • Vertigo is classified into either peripheral or central depending on the location of the dysfunction of the vestibular pathway, although it can also be caused by psychological factors. (wikipedia.org)
  • blood
  • Is believed to tone blood and improve sperm count. (hubpages.com)
  • Adverse effects of eldecalcitol include an increase in blood and urinary calcium levels. (wikipedia.org)
  • The primary action of nicergoline is to increase arterial blood flow by vasodilation. (wikipedia.org)
  • Acquired risk factors include the strong risk factor of older age, which alters blood composition to favor clotting. (wikipedia.org)
  • Oral contraceptives and hormonal replacement therapy increase the risk through a variety of mechanisms, including altered blood coagulation protein levels and reduced fibrinolysis. (wikipedia.org)
  • Another factor in older populations is impairment of blood supply. (wikipedia.org)
  • Low blood pressure is initially treated with fluids along with bicarbonate to reverse metabolic acidosis (if present), if the blood pressure remains low despite fluids then further measures such as the administration of epinephrine, norepinephrine, or dopamine can be used to increase blood pressure. (wikipedia.org)
  • GWAS
  • The first GWAS, conducted in 2005, studied patients with age-related macular degeneration (ARMD). (wikipedia.org)
  • older
  • In the past couple of decades, the number of older fathers has increased. (cartercenter.org)
  • The day after Henry was born, while we were still bleary-eyed from a late-night cesarean delivery, we caught part of a report on the hospital television about an increased risk of autism in the children of older fathers. (cartercenter.org)
  • What was most frightening to me, as someone with mental illness in the family, is that older fatherhood was also associated with an increased risk of schizophrenia. (cartercenter.org)
  • Between November 1998 and September 2001, the multicenter research team enrolled more than 38,500 men and women age 60 or older into the study. (bio-medicine.org)
  • involves
  • The function of perlipin 2 involves the formation of lipid droplets, formation of fatty liver by increasing uptake of fatty acids etc. (wikipedia.org)
  • exposure
  • Risk factors are related to excessive unopposed exposure of the endometrium to estrogen, including unopposed estrogen therapy, early menarche, late menopause, tamoxifen therapy, nulliparity, infertility or failure to ovulate, and polycystic ovary syndrome. (aafp.org)
  • time
  • These striking results indicate for the first time that we can use a vaccine to prevent shingles, one of the most common and debilitating illnesses of aging. (bio-medicine.org)
  • Fortunately, some of these injuries can be prevented with the availability of patient lifts, improved worker training, and allocation of more time to perform work procedures. (wikipedia.org)
  • Due to a rapid compensation process, acute vertigo as a result of a peripheral lesion tends to improve in a short period of time (days to weeks). (wikipedia.org)
  • Ultimately, most are the result of wear that occurs slowly over time as a natural part of aging. (wikipedia.org)
  • syndrome
  • It is widely recognized that a 40-year-old woman has an increased risk of bearing a child with Down syndrome. (cartercenter.org)
  • The final common factor is impingement syndrome, the most common non-sports related injury and which occurs when the tendons of the rotator cuff muscles become irritated and inflamed while passing through the subacromial space beneath the acromion. (wikipedia.org)
  • population
  • Much of that jump is the result of an increase in the overall population. (cartercenter.org)
  • In the aging population, the bone matrix becomes weakened through untreated osteoporosis. (wikipedia.org)
  • In the United States in 1998 17 million workers were over age 55 and by 2018 this population is expected to more than double. (wikipedia.org)
  • chronic
  • Several factors contribute to degenerative, or chronic, rotator cuff tears of which repetitive stress is the most significant. (wikipedia.org)
  • levels
  • Calcium absorption increases with the presence of eldecalcitol by the body, occurring in the intestines, which is useful for those who have low calcium levels. (wikipedia.org)
  • Increase in mRNA levels is one of the earliest indications of adipocyte differentiation. (wikipedia.org)
  • known
  • Dosages for known conditions are usually administered at 5-10 mg three times a day, however anti-aging preventative purposes may want to consider 5 mg once or twice a day more adequate. (wikipedia.org)
  • At high dosages bradycardia, increased appetite, agitation, diarrhea and perspiration have been known to occur. (wikipedia.org)
  • although
  • When OC content of the soil clays was reduced by H2O2, sorption decreased, although Koc increased. (usda.gov)
  • This is referred to as the age of majority, which is age 18 in most cultures, although there is variation from 16 to 21. (wikipedia.org)
  • several
  • Indeed, several studies using aged mouse18,20,21 and human oocytes21,22,23 reported increased sister IKT distances during meiosis I that buy 80223-99-0 result in merotelic attachments (i.e., a single kinetochore is bound to microtubules from both spindle poles) and aneuploidy15. (healthweeks.com)
  • In addition to the conceptual framework several additional factors enabled the GWA studies. (wikipedia.org)
  • Several Congressional Budget Office reports said that overall these provisions reduced the budget deficit, and that repealing the ACA would increase the deficit. (wikipedia.org)
  • health
  • The idea that a father's age could affect the health of his children was first hinted at a century ago by an unusually perceptive and industrious doctor in private practice in Stuttgart, Germany. (cartercenter.org)
  • The concepts of personalised health care are receiving increasing acceptance with the Veterans Administration committing to personalised, proactive patient driven care for all veterans. (wikipedia.org)
  • studies
  • Sandage performed photometric studies of globular clusters, and calculated their age to be at least 25 billion years. (wikipedia.org)
  • pressure
  • This increased pressure can damage the optic nerve and lead to vision loss and blindness. (rochester.edu)
  • Increased pressure in the eye means you are at risk for glaucoma, the NEI says, but it doesn't mean you have glaucoma. (rochester.edu)
  • If you have increased eye pressure but no damage to the optic nerve, you do not have glaucoma, the NEI says. (rochester.edu)
  • Not every person with increased pressure develops glaucoma, and the pressure that causes damage may be different for each person. (rochester.edu)
  • patients
  • Bone geometry assessments show that eldecalcitol increases cortical bone area in patients with osteoporosis more so than other vitamin D analogs, such as alfacalcidol. (wikipedia.org)
  • pain
  • As immunity weakens with advancing age, the virus can reactivate, multiply in and damage sensory nerve cells to cause pain. (bio-medicine.org)