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  • prostate cancer
  • Primary endpoint was ≥50% decline in 12-week PSA according to Prostate Cancer Working Group 2 criteria. (aacrjournals.org)
  • Most prostate cancer deaths are attributable to this castration-resistant form of prostate cancer (CRPC). (hindawi.com)
  • Moreover, androgens are important for the development and progression of age-associated pathologies in men, including benign prostatic hyperplasia and prostate cancer (PC). (hindawi.com)
  • The most commonly used therapies in metastatic prostate cancer involve androgen deprivation through medical (LHRH agonists), surgical castration, or disruption of androgen binding to AR [ 3 ]. (hindawi.com)
  • Importantly, even in castration resistant prostate cancer (CRPC), AR still plays an essential role in cancer progression [ 6 ]. (hindawi.com)
  • Guided by the theoretical domains framework (TDF), urologists and patients from facilities with the highest and lowest castration rates across the VA will be interviewed to identify key preferences and de-implementation barriers for reducing castration as prostate cancer treatment. (biomedcentral.com)
  • The investigators will conduct national surveys of urologists to prioritize key barriers identified in Aim 1 for stopping incident castration as localized prostate cancer treatment using a DCE experiment design. (biomedcentral.com)
  • Aim 3: To pilot two tailored de-implementation strategies to reduce castration as localized prostate cancer treatment. (biomedcentral.com)
  • The primary objective of this prospective study was to establish the relationship between posttreatment CTC count and overall survival (OS) in castration-resistant prostate cancer (CRPC). (aacrjournals.org)
  • This method for enumerating circulating tumor cells (CTC) may have utility in predicting prognosis and monitoring the antitumor effects of treatment in castration resistant prostate cancer. (aacrjournals.org)
  • Castration-resistant prostate cancer (CRPC) may be a more accurate description for this disease because it can remain hormone-driven despite androgen deprivation ( 1 , 2 ). (aacrjournals.org)
  • painful
  • She is known for her foundational research on assessing welfare in beef cattle including the impacts of long-distance transportation, developing producer-friendly pain mitigation strategies for castration and other painful procedures and assessing and mitigating lameness in feedlot cattle that has informed regulations and guidelines for the commercial beef cattle industry in North America. (wikipedia.org)
  • evidence
  • Voluntary castration for homosexuality was also state policy in Netherlands at that point, as well against Catholic canon law, and there has been no evidence suggesting the Church had a part in organizing the procedures. (wikipedia.org)
  • veterinary
  • To alleviate the hardships they face, World Vets has been providing free veterinary services for the working horse population in Nicaragua for many years. (worldvets.org)
  • Instead of operating out of a teaching facility, students will work in a non-clinic environment and in turn be exposed to practicing veterinary medicine in a field-clinic setting. (worldvets.org)
  • Instead you will work in field clinic conditions where we will operate a fully functional mobile surgery setup and travel with the veterinary supplies needed to provide routine veterinary care. (worldvets.org)
  • surgery
  • Potential side effects are mostly related to surgery such as anesthetic complications (including death), cutting the wrong structure (such as the ureter and major blood vessels which lie close to the ductus deferens) and incompletely severing the ductus deferens (which may heal and still be functional). (avianstudios.com)
  • Germaine makes attempts to reform her character and personality, including changing her hair and getting breast-reduction surgery. (wikipedia.org)
  • nine
  • It also received nine BAFTA nominations, including Best Film and Outstanding British Film, and won the People's Choice Award at the 39th Toronto International Film Festival. (wikipedia.org)
  • uses
  • Pierrot Lunaire uses a variety of classical forms and techniques, including canon, fugue, rondo, passacaglia and free counterpoint. (wikipedia.org)
  • make
  • I was proud of having worked with people who make a difference in the life of an animal. (worldvets.org)
  • The eunuchs were assigned to do work for the palace women like massaging and applying make up to the women and preparing them for sex with the Emperor. (wikipedia.org)
  • known
  • The term "castration" is sometimes also used to refer to the removal of the ovaries in the female, otherwise known as an oophorectomy or, in animals, spaying. (wikipedia.org)
  • Following several years in the Japanese noise rock scene that included collaborations with Merzbow and Hanatarashi, experimental noise rock guitarist and electronic programmer KK Null formed Zeni Geva in 1987 with guitarist Fumiyoshi Suzuki (also known as "NP"), vocalist Elle, and drummer Ikuo Taketani of the Japanese experimental groups The Boredoms and Hanatarashi. (wikipedia.org)
  • probably
  • These horses require careful attention from an equine veterinarian as IV fluid administration and blood work are essential and support with a sling will probably be required. (horsefeedblog.com)
  • events
  • Recent work has shed light on the importance of epigenetic events including facilitation of AR signaling by histone-modifying enzymes, posttranslational modifications of AR such as sumoylation. (hindawi.com)
  • sexual
  • In Judith, for instance, Hermann reads the decapitation of Holofernes not just as a symbolic castration but also allegorically, as Christian abnegation of the self, but also tropologically, as signifying the disclipining of especially sexual desire within a group, a notion he relates to the poem's monastic provenance. (wikipedia.org)
  • studies
  • His work is inspired by travels throughout the Caribbean and seacoast islands of the southern United States, and by the migrations of people of African and Caribbean descent to the Americas," according to the University of North Carolina Charlotte Africana Studies Department where Reddy was a visiting artist in 2008-2009. (wikipedia.org)
  • several
  • Our dedication to innovation has positioned us as a driving market force in several key technology areas, including highly power-efficient mobile technologies and advanced multimedia solutions across a broad range of products such as smartphones, tablets, digital televisions, OTT boxes, wearables and automotive solutions. (turkeynewsgazette.com)
  • Cuesta, who worked for several magazines, founded his own magazine in 1932, named Examen. (wikipedia.org)
  • Null remained prolific via solo and collaborative releases, while Tabata worked with several projects, including Acid Mothers Temple. (wikipedia.org)
  • take
  • So we finish our vet work, take an inventory of supplies, organize the storage trunks so the next group can start off well, and clean up. (gardnervet.com)
  • male
  • Joan Clarke, a Cambridge graduate, surpasses Turing's test but her parents will not allow her to work with the male cryptographers. (wikipedia.org)
  • live
  • Turing arranges for her to live and work with the female clerks who intercept the messages, and shares his plans with her. (wikipedia.org)
  • blog
  • This fun and fact-filled blog is updated regularly and includes up-to-date information about your pet's health care. (gardnervet.com)
  • Also included in the blog are fun, pet-related news stories that we want to share with you and photos and information about our hospital and staff members. (gardnervet.com)
  • Activity
  • Recent work indicates that epigenetic enzymes are important coactivators of AR and may represent targets to influence AR stability and activity, thus providing new therapeutic opportunities to overcome mechanisms of resistance. (hindawi.com)
  • The New York Times columnist Tom Wicker wrote that it was "one more of those vengeful miscarriages of justice by which comfortable society attempted to label urban unrest, racial disorders … and anti-war activity as the work of agitators and terrorists. (wikipedia.org)
  • often
  • Our main focus has been to improve the comfort and quality of life of working horses, and so we often distribute donated halters, leads and padding to horse owners as well. (worldvets.org)
  • a work which in later generations would often only be somewhat tacitly or glancingly acknowledged as an achievement only made possible by his acceptance and endurance of punitive actions against him, including imprisonment, castration, and subjection to servility. (wikipedia.org)
  • care
  • This work will broadly advance de-implementation science for low value cancer care, and foster participation in our de-implementation evaluation trial by addressing barriers, facilitators, and concerns through pilot tailoring. (biomedcentral.com)
  • high
  • Complete feeds, particularly Senior Feeds, also work very well in this situation with controlled starch and sugar levels, amino acid profile, high digestibility, and easy to chew attributes. (horsefeedblog.com)
  • reasons
  • Two reasons provided for the change-over included poor quality copies being made and distributed without credit to Mathers. (wikipedia.org)
  • theory
  • Freud sought to link to his theory of the unconscious put forward in The Interpretation of Dreams (1899) and his work on hysteria by positing sexuality as the driving force of both neuroses (through repression) and perversion. (wikipedia.org)
  • superior
  • Moreover, indications of superior efficacy, including significantly greater relative decreases and increases in levels of prostate-specific antigen (PSA) and testosterone, respectively, were observed. (wikipedia.org)
  • Strachey's translation is generally considered superior, including by Freud himself. (wikipedia.org)
  • life
  • In Chicago, Beach met and worked with behaviorist Karl Lashley, who had perhaps the strongest influence on Beach's professional life. (wikipedia.org)
  • data
  • There are inherent limitations in MediaTek Sensio and related software and other factors that may affect the accuracy of the information and data provided by MediaTek Sensio and related software, including heart rate readings, such as environmental conditions, skin conditions, specific activities performed, designs or settings of the device, sensor placement, and other end-user interactions. (turkeynewsgazette.com)
  • people
  • Schoenberg, who was fascinated by numerology, also makes great use of seven-note motifs throughout the work, while the ensemble (with conductor) comprises seven people. (wikipedia.org)
  • solo
  • His work was on display in a 2013 exhibit on the Civil Rights Movement at the Levine Museum of the New South in Charlotte, N.C. A solo exhibition of his work was held in 2014 at the St. Helena (SC). (wikipedia.org)
  • hormonal
  • Although this was possible for castrati because of the hormonal imbalance following castration, Maniaci claims that, for some unknown reason, his larynx did not develop and lengthen completely during puberty, causing his voice not to "break" in the usual manner. (wikipedia.org)
  • symptoms
  • Though low or suboptimal testosterone levels can contribute to changes in libido and the ability to achieve or maintain an erection, symptoms are varied and often include fatigue, apathy, difficulty concentrating, weight gain, depression, sleep disturbances and, most importantly, changes in metabolism including an increased risk for metabolic and cardiovascular disease. (pdxnd.com)
  • Other late symptoms may include feeling tired due to low levels of red blood cells. (wikipedia.org)
  • Side effects of the GnRH agonists are signs and symptoms of hypoestrogenism, including hot flashes, headaches, and osteoporosis. (wikipedia.org)
  • patients
  • In an editorial 3 accompanying the journal article and a podcast on the journal website, Dr. Partridge, who works mainly with patients who have breast cancer, noted that the use of GnRH agonists "is appealing, given that they are readily available and are generally less cumbersome than available alternative strategies including in vitro fertilization and embryo cryopreservation before treatment. (ascopost.com)
  • At Mount Sinai, he has continued this work and developed a database of iver 1500 patients. (wikipedia.org)
  • appearances
  • citation needed] Video appearances include "Rain" - Madonna, "Mistletoe And Wine" - Sir Cliff Richard, "Loves In The Neighbourhood" - His Latest Flame, "Good Guys Only Win In The Movies" - C. C. Catch. (wikipedia.org)
  • His orchestral engagements have included appearances with Tafelmusik, the New Holland Baroque Orchestra, the Bridgehampton Chamber Music Festival, and a tour with Academie Baroque de Montréal throughout Canada and Germany. (wikipedia.org)
  • Upon
  • Upon being drafted to the Israel Defense Forces, he served in a Nahal unit that combined military training with agricultural work on a kibbutz. (wikipedia.org)
  • In the middle of the night, the explorers are awakened by chanting, and happen upon the rumored cult (which includes the sheriff) performing a Satanic sexual ritual involving Wanda, and an effigy of Bigfoot. (wikipedia.org)
  • Arabs
  • Already in these early works, Loevy focused on two themes that would dominate his laterprojects: the tense relationship between Arabs and Jews in Israel, and the role of education and art in shaping a society. (wikipedia.org)
  • producers
  • Scruggs noted that castration and dehorning are some of the main stressors on the immune system, so producers should do these as early as possible to minimize blood loss and allow for a faster immune system recovery. (beefmagazine.com)
  • Because these are often the viral agents producers vaccinate for, confirming a purchased calf's vaccinations and working with your veterinarian to incorporate a modified-live vaccine on arrival is an important step in managing BRD. (beefmagazine.com)
  • sexual
  • Other artists deny that their works are sexual, although critics view them as such: the flower paintings of Georgia O'Keeffe are a case in point. (wikipedia.org)
  • Various perceptions of the vagina have existed throughout history, including the belief it is the center of sexual desire, a metaphor for life via birth, inferior to the penis, visually unappealing, inherently unpleasant to smell, or otherwise vulgar. (wikipedia.org)
  • Sometimes
  • Sometimes these are explicitly works of feminist art: Judy Chicago created The Dinner Party to celebrate 39 women of history, many of whom had fallen into obscurity. (wikipedia.org)
  • Three Essays on the Theory of Sexuality (German: Drei Abhandlungen zur Sexualtheorie), sometimes titled Three Contributions to the Theory of Sex, is a 1905 work by Sigmund Freud which advanced his theory of sexuality, in particular its relation to childhood. (wikipedia.org)
  • Risk
  • Risk factors for mammary neoplasia in female dogs include age, breed ( Table 1 ), and sexually intact status. (petmd.com)
  • early
  • He began the first canto of Don Juan in late 1818, and he was still at work on a seventeenth canto in early 1823. (wikipedia.org)
  • people
  • I am proud to be part of a diverse, talented group of people all working with one aim - to improve patient outcomes. (astrazeneca.com)
  • In keeping in touch with these people through their pets, the school is also partnering with the school of social work and the pharmacy school as it's looking at not only the health of animals, but also people who need help in the community. (blogspot.com)
  • A vital naval city for Polish grain trade it attracted people from all over the European continent, including Germans and Scots. (wikipedia.org)
  • studies
  • Soon after the war, he returned to London to continue his studies and worked as an assistant director at Elstree Studios for the British espionage/science fiction adventure series The Champions. (wikipedia.org)
  • complete
  • Suspecting his time was running out, he summoned his son back home to complete the historical work he had begun. (wikipedia.org)
  • often
  • a work which in later generations would often only be somewhat tacitly or glancingly acknowledged as an achievement only made possible by his acceptance and endurance of punitive actions against him, including imprisonment, castration, and subjection to servility. (wikipedia.org)
  • site
  • The only site you need for word puzzles, home work, anagrams and scrabble games. (unscramble.net)
  • He featured on the Saatchi online Web site where his work is likened to Graham Sutherland and Ceri Richards. (wikipedia.org)
  • major
  • Though the film was set in the relatively distant past, in 1932, this first attempt at drama already hints at two of the major themes that appear throughout Loevy's later work: class distinctions and ethnic differences. (wikipedia.org)
  • Other major exports included cloves and nutmegs, as well as betel nuts, whose narcotic properties bypassed the Muslim prohibition of alcohol. (wikipedia.org)
  • final
  • Usage of GnRH agonist for this purpose necessitates using a GnRH antagonist instead of a GnRH agonist for suppression of spontaneous ovulation, because using GnRH agonist for that purpose as well inactivates the axis for which it is intended to work for final maturation induction. (wikipedia.org)
  • Television
  • In 1993, Loevy was awarded the Israel Prize in Communication, Radio and Television in 1993 for his life's work. (wikipedia.org)
  • happen
  • Byron claimed that he had no ideas in his mind as to what would happen in subsequent cantos as he wrote his work. (wikipedia.org)