This study was undertaken to determine the influences of various doses of peppermint oil on the hepatic en-zymes, alanine transaminase, apartate tranaminase, alkaline phosphotase and gamma glutamyl transferase and the level of malondialdehyde in the serum of mice with and without immobility stress. (openbiochemistryjournal.com)
Alkaline1
The Clinical Laboratory Improvement Amendments criteria were used in evaluating the laboratories, and their success rates were compared with the World Health Organization Regional Office for Africa's target of 80%.Results: The overall rate of acceptable results at the laboratories was over 80% for glucose, alanine aminotransferase, aspartate aminotransferase, gamma-glutamyltransferase, alkaline phosphatase and triglycerides tests. (bvsalud.org)
Retrospective4
In this retrospective, cross-sectional study, a total of 60 children with a diagnosis of acute pancreatitis, were studied. (biomedcentral.com)
In this retrospective, cross-sectional study, a total of 60 children with a diagnosis of acute pancreatitis, admitted to Children's Medical Center Hospital in Tehran, Iran, from 2013 to 2020, were studied. (biomedcentral.com)
This was a retrospective longitudinal trends study involving hospitalizations with AWD in the USA from 2010 to 2019. (gastrores.org)
A retrospective, descriptive study was conducted over the 4-year-period 2014 - 2017. (bvsalud.org)
Methods3
The aim of this study was to investigate the common causes and routine diagnostic and therapeutic methods of acute pancreatitis in children in a pediatric gastrointestinal referral center and its accordance with existing guidelines. (biomedcentral.com)
However, participation in such PT programmes assists improves test performance and result accuracy.Objective: This study assessed how well 11 government hospital laboratories performed 18 basic clinical chemistry tests and identified areas needing improvement.Methods: A cross-sectional study was carried out by the Division of Laboratories of the Ministry of Health of Togo from 01 July 2016 to 31 December 2016. (bvsalud.org)
Neutropenia2
Neupogen is indicated for the treatment of persistent neutropenia (ANC less than or equal to 1.0 × 10 9 /l) in patients with advanced HIV infection, in order to reduce the risk of bacterial infections when other options to manage neutropenia are inappropriate. (medicines.org.uk)
Kupitral is also indicated in the prevention of fungal infection during prolonged neutropenia when standard therapy is considered inappropriate. (pillintrip.com)
Pediatric1
Most common adverse drug reactions (≥5%) from clinical trials in pediatric patients were anemia, vomiting, increased gamma-glutamyltransferase, and cholestasis. (drugs.com)
Ineffective2
Sandostatin LAR is also indicated for the treatment of patients with acromegaly in whom surgery or radiotherapy is inappropriate of ineffective or in the interim period until radiotherapy becomes fully effective. (camurus.com)
7. Kupitral is indicated in the following systemic fungal conditions when first-line systemic anti-fungal therapy is inappropriate or has proved ineffective. (pillintrip.com)
Clinical4
In clinical education, the risks of radiation due to unnecessary CT scans and inappropriate prescription of antibiotics need to be emphasized. (biomedcentral.com)
As only few original studies have investigated acute pancreatitis in children in Iran, in the present study, the clinical manifestations and etiological factors of this disease, as well as diagnostic and therapeutic measures, were investigated in children. (biomedcentral.com)
The CAM2029 product has been studied in four Phase 1/2 clinical trials, which have evaluated the safety and tolerability as well as pharmacokinetic and pharmacodynamic properties of the product in a total of about 250 individuals. (camurus.com)
This study showed that there is still a high discrepancy between clinical diagnoses and postmortem findings, similar to studies conducted globally. (bvsalud.org)
Systemic1
Therefore functional retuning of TAM to an M1 phenotype is paramount for effective immunotherapy against established tumors which could be afforded by systemic application of low dose gamma irradiation in neo adjuvant setting of late-stage human insulinoma (Pan-NET) bearing Rip1-Tag5 mice. (biomedfrontiers.org)
Investigate1
This study aimed to investigate the seroepidemiology and risk factors associated with the endemicity of Theileria equi infection in Rajasthan state. (arccjournals.com)
Formulation1
Lund - 12 July 2016 - Camurus announces the completion of a multi-center Phase 2 study of long-acting octreotide FluidCrystal® formulation (CAM2029), supporting its potential in treating patients with acromegaly or neuroendocrine tumors (NETs). (camurus.com)
Doses1
As a new feather in the traditional radiation therapy, we have previously shown the therapeutic impact of low doses of gamma irradiation (LDI) on peritumoral macrophages as a potential non-invasive approach to improve cancer immunotherapy by enhancing tumor directed T-cell infiltration and subsequent tumor rejection (Klug and Prakash et al 2013). (biomedfrontiers.org)
Potentially1
Several researchers have theorized that altered or inappropriate immune responses, potentially involving abnormal B-cell activation and neuronal function, may play a role in the pathophysiology. (medscape.com)
Patients8
Based on the evaluation of medical records, patients under the age of 18 years, who met the diagnostic criteria for acute pancreatitis according to the INSPPIRE criteria, were included in the study. (biomedcentral.com)
This study aimed to assess the risk and predictors of HCC in Korean patients with alcoholic cirrhosis by using competing risk analysis. (nature.com)
In this study, we sought to perform a competing-risk analysis for predicting the risk and predictors of HCC in alcoholic cirrhosis patients in Korea. (nature.com)
The results from this Phase 2 study of CAM2029 are encouraging, with long-acting octreotide release and sustained disease control seen in patients with acromegaly as well as neuroendocrine tumors," said lead investigator Professor Marianne Pavel, MD, Senior Physician and Leader of the Section for Neuroendocrine Tumors in the Department of Hepatology and Gastroenterology at the Charité-Universitätsmedizin, Berlin, Germany. (camurus.com)
The positive pharmacokinetic profile and promising disease control data seen in this Phase 2 study when switching patients from Sandostatin®LAR®to CAM2029, together with the option for self-administration by patients, underscores the potential for CAM2029 to fill an unmet medical need," said Fredrik Tiberg, PhD, President & CEO of Camurus. (camurus.com)
4 , 11 - 19 Notably, a number of studies have provided evidence that the criteria associated with MAFLD are more effective than the criteria associated with NAFLD when it comes to identifying patients with significant fibrosis as well as chronic kidney and cardiovascular diseases, including those with fatty liver disease and other concomitant liver diseases. (xiahepublishing.com)
The aim of this study was to evaluate the efficacy and safety of rehabilitation exercises, which have been individually prescribed via an mHealth app, on physical fitness, body composition, biochemical profile, and quality of life among HCC patients. (jmir.org)
As prophylaxis of deep fungal infections anticipated to be susceptible to Kupitral, when standard therapy is considered inappropriate, in patients with haematological malignancy or undergoing bone marrow transplant, and who are expected to become neutropenic (i.e. (pillintrip.com)
Acute1
More research should be done to study the association between COVID-19 and acute pancreatitis. (biomedcentral.com)
Disease1
Risk factors for coronary artery disease (CAD) were not formally established until the initial findings of the Framingham Heart Study in the early 1960s. (medscape.com)
Cross-secti1
A cross-sectional study on the seroprevalence of Theileria equi , was performed. (arccjournals.com)
Factors1
In this study, the underlying factors of successful and unsuccessful FMT treatment cases are elucidated, and the potential markers for predicting successful FMT are identified using fecal metagenomics via 16S rRNA gene sequencing, fecal metabolomics via capillary electrophoresis time-of-flight mass spectrometry, and machine learning approaches. (biomedcentral.com)
Objective2
These photographs will serve the dual objective of quick review and self-evaluation for college students and will appeal to Pathology lecturers who could use them for their lectures, being assured that their students will have entry to the same materials for evaluation and study. (ehd.org)
The study objective was to provide information regarding perioperative characteristics, complications, and outcomes of dogs undergoing treatment of ICLs. (biomedcentral.com)
Prospective1
Ultrasound-derived fat fraction (UDFF) is based on a combination of backscatter coefficient and attenuation parameter.The objectives of the study were to determine (1) agreement between UDFF/MRI proton density fat fraction (MR-PDFF) and (2) whether BMI and age are predictive for UDFF.This cross-sectional prospective study included a convenience sample of 46 children referred for clinically indicated abdominal MRI. (stanford.edu)
Assess1
open-label multicentre, randomised study to assess the PK, PD, efficacy, and safety of two dosing regimens of CAM2029. (camurus.com)
Incidence2
Another recent Danish study showed similar result (cumulative incidence of 6.0% after 10 years) 10 . (nature.com)
Our study showed an increase in the incidence and admission rates of AWD. (gastrores.org)
Report2
Collaborative Ocular Melanoma Study Group Report 23. (jamanetwork.com)
Screening for metastasis from choroidal melanoma: the Collaborative Ocular Melanoma Study Group Report 23. (jamanetwork.com)
Bias1
The risk of bias of the included studies was assessed using the Cochrane tool. (degruyter.com)
Regard1
In this regard, some studies have found that lithium and hyperbaric oxygen[4] reduce oxidative stress and may increase blood flow to the brain, lending some support to the idea that a possible endophenotype leads to oxidative stress and neuronal injury. (medscape.com)
Therapeutic1
In the present study, treatment with CAM2029 resulted in therapeutic blood-levels of octreotide over four weeks. (camurus.com)
Found1
Most interestingly, presence of peritumoral macrophages was found indispensible for gamma irradiation triggered M1 retuning of insulinoma demonstrating the critical role of M1 effector macrophages for retuning of insulinoma tumor micromillieu. (biomedfrontiers.org)
Period3
In this study, we utilized the Nationwide Inpatient Sample to examine the trends of alcohol withdrawal delirium (AWD) in the period 2010 - 2019. (gastrores.org)
There were statistically significant trends of increasing inpatient mortality, THC, and LOS over the studied period. (gastrores.org)
Mortality, LOS, and THC increased over the studied period. (gastrores.org)
Cases1
A total of 288 cases qualified for the study and were evaluated. (bvsalud.org)
Previous1
BACKGROUND: In a previous study, telmisartan suppressed aldosterone secretion in healthy cats but not in cats with primary hyperaldosteronism (PHA). (bvsalud.org)
Drug1
In drug studies, cefovecin administered to dogs was 92.4% effective against skin infections (secondary superficial pyoderma, abscesses, and infected wounds). (wikipedia.org)
Increase1
They increase an affected patient's risk of developing recurrent inappropriate blood clots (thrombi) in arteries and veins, which can lead to strokes and heart attacks . (labtestsonline.org.uk)
Healthy1
Haematological observations in T. equi clinically infected and healthy horses were studies. (arccjournals.com)