Acute or chronic inflammation induced by ischemia has also been suggested to play an important role in the process of malignant cardiac remodeling [ 3 ]. (hindawi.com)
Coronary artery disease is often characterized by lesions or occlusions in the coronary arteries which may result in inadequate blood flow to the myocardium, or myocardial ischemia, which is typically responsible for such complications as angina pectoris, necrosis of cardiac tissue (myocardial infarction), and sudden death. (justia.com)
Myocardial ischemia results when the blood supply from the coronary arteries is unable to keep up with the increased oxygen demand of the myocardium due to cardiac hypertrophy. (alliedacademies.org)
Heart failure is the inability of the cardiac systolic and/or diastolic functions to completely empty the veins of the heart's blood, which ultimately results in venous system blood stasis and inadequate arterial blood perfusion. (alliedacademies.org)
The ECG provides 3-dimensional information about the conduction system of the heart, the myocardium, and other cardiac structures. (lecturio.com)
Troponin elevation in the absence of clinical evidence of ischemia should prompt a search for other causes of cardiac damage, such as myocarditis. (medscape.com)
Through balloon inflations and deflations synchronized with the natural heartbeat the IABP increases diastolic aortic pressure, which enhances diastolic blood flow to the coronary arteries and vital organs, as well as reduces systolic aortic pressure, which reduces afterload and oxygen consumption of the myocardium and increases cardiac output. (cochrane.org)
Oxygenation4
citation needed] Ischemia, or inadequate oxygenation of the myocardium, is observed in a high proportion of HFpEF patients. (wikipedia.org)
1 Coronary artery disease can lead to inadequate tissue oxygenation, a state known as ischemia. (cms.gov)
It can be caused by infection (often viral), myocardial infarctionMyocardial infarction MI is ischemia and death of an area of myocardial tissue due to insufficient blood flow and oxygenation, usually from thrombus formation on a ruptured atherosclerotic plaque in the epicardial arteries. (lecturio.com)
Thus, simultaneous information about electrical ac-tivity, oxygenation, and contractility in lo-cally altered myocardium and adjacent, un-disturbed muscle became available. (1library.net)
Perfusion4
When this decrease in perfusion occurs and is not alleviated, that section of myocardium progresses to permanent damage and cell death. (cms.gov)
Inadequate myocardial perfusion likely causes significant chest pain and these symptoms of myocardial ischemia may be misinterpreted as routine infantile colic. (medscape.com)
In DMD, the signaling defects produce inadequate tissue perfusion caused by functional ischemia due to a diminished ability to respond to shear stress induced endothelium-dependent dilation. (biomedcentral.com)
Blood flow to the myocardium served by a particular coronary artery is not significantly decreased until a lesion blocks about 70% of the diameter of the artery. (thedenverdisabilitylawyer.com)
As previously discussed, the keys to achieving a good outcome in patients with cardiogenic shock are rapid diagnosis, prompt supportive therapy, and expeditious coronary artery revascularization in patients with myocardial ischemia and infarction. (medscape.com)
Other etiologies of myocardial ischemia include coronary artery embolism, which accounts for 2.9% of patients, cocaine-induced ischemia, coronary dissection, and coronary vasospasm. (statpearls.com)
Currently, CABG-related MI is defined as (1) biomarker level elevations more than 5 times the upper reference limit plus either new pathological Q waves or new left bundle branch block (LBBB), (2) angiographically documented new graft or native coronary artery occlusion, or (3) imaging evidence of new loss of viable myocardium. (medscape.com)
Contractility1
While striking chanares of polaro-graphic oxygen and contractility regularly occur a few seconds after coronary arterial branch occlusion, epieardial electrocardio-graphic changes are delayed and sometimes absent.1 Intramyocardial electrocardiographic studies, on the other hand, reveal that local-ized ischemia disturbs myocardial electrical activity at least as early as either oxygena-tion or contractility, and over a more exten-sive area. (1library.net)
Infarction2
Myocardial infarction (MI) causes permanent damage to the heart muscle due to inadequate oxygen supply. (statpearls.com)
Ischemia may manifest in distinct ways, either as a result of increasing tissue oxygen demand, or diminished ability of the heart to supply oxygen to the tissue. (wikipedia.org)
E HAVE previously shown that the enicardial-surface electrocardiogram is an inadequate index of localized myocardial ischemia. (1library.net)
Transient2
Initially, myocardial ischemia is transient, occurring during periods of increased myocardial demands, such as when the infant is feeding and crying. (medscape.com)
Silent ischemia sometimes manifests as transient asymptomatic ST-T abnormalities seen during stress testing or 24-h Holter monitoring. (rxharun.com)
Venous1
The recumbent position increases venous return, stretching the myocardium and increasing wall stress, which increases oxygen demand. (rxharun.com)
Defects1
Heart failure (HF) is a syndrome caused by structural and functional defects in myocardium resulting in impairment of ventricular filling or the ejection of blood. (themorninglead.com)
Apoptosis2
The aim of this study was to investigate whether resveratrol (RSV) could ameliorate ischemia- and hypoxia-associated cardiomyocyte apoptosis and injury via inhibiting senescence signaling and inflammasome activation. (hindawi.com)
Major pathogenic mechanisms leading to HF are increased hemodynamic overload, ischemia-related dysfunction, ventricular remodeling, excessive neuro-humoral stimulation, abnormal myocyte calcium cycling, excessive or inadequate proliferation of the extracellular matrix, accelerated apoptosis and genetic mutations. (themorninglead.com)
Arteries2
Common characteristics of IHD are the obstruction or narrowing of arteries and arterioles resulted in inadequate supply of oxygenated blood for the myocardium [ 1 ]. (hindawi.com)
These increases may be the cause of rest angina or the result of ischemia induced by plaque rupture and thrombus formation. (rxharun.com)
When combined to regular antianginal medication, nicorandil significantly reduced the frequency of ischemia episodes in coronary heart disease (CHD) patients with stable angina. (ijtpr.com)
Acute1
Angiograph before and after thrombolytic therapy in a case of acute limb ischemia . (wikimili.com)
Inability1
Heart failure is characterized by an inability of the myocardium to deliver sufficient oxygenated blood to meet the needs of tissues and organs during exercise or at rest. (aafp.org)
Functional1
Several recent studies on novel DMD therapeutics are vascular targeted and focused on attenuating the inherent functional ischemia. (biomedcentral.com)
Baseline1
Of the 422 patients who consented to participate, 22 (5.2%) met exclusion criteria (10 with inadequate baseline echocardiographic image quality, 3 with sulfonamide allergy, and 9 with severe chronic obstructive pulmonary disease). (thoracickey.com)
Patients1
Small randomised trials suffered from inadequate power to address deaths and harmful effects of IABP and were biased by frequent cross-over to the more aggressive strategy, early stopping of the trial, or the inclusion of patients with IABP at randomisation. (cochrane.org)
Increased vascular wall sclerosis and decreased compliance are the main signs of vascular calcification, which can quickly result in myocardial ischemia, left ventricular hypertrophy, and heart failure. (alliedacademies.org)
Shock1
Insufficient delivery of oxygen and destruction of red blood cells may cause cardiopulmonary complaints with the development of ischemia, arrhythmia and shock. (cdc.gov)
Adverse1
Inadequate response to treatment in coronary heart disease adverse effects of type D personality and Coronary circulation, part of the systemic circulatory system that supplies blood to and provides drainage from the tissues of the heart. (web.app)
Syndrome1
These discoveries allow us to affirm with tranquility that the Brugada brothers were the true discoverers of the syndrome, considering the claim of the Italian authors inadequate. (bvsalud.org)
Heart failure1
Two studies presented at the American Heart Association meeting showing only the safety and feasibility, not efficacy, of stem cell therapy in ischemia-induced heart failure evoked loud acclaim by the national media. (jwatch.org)
Injury3
Our findings revealed that RSV protected against ischemia-induced mouse heart injury in vivo and hypoxia-induced NRCM injury in vitro via regulating Sirt1/p53-mediated cell senescence and inhibiting NLRP3-mediated inflammasome activation. (hindawi.com)
Three distinct pathophysiological processes are critical in the development of 'no reflow' after PPCI for STEMI: distal embolization, ischemia-reperfusion injury, and individual susceptibility [ 4 ]. (biomedcentral.com)
Current methods of cold static storage have reached their limits in storage time due to the extent of ischemia-reperfusion (I/R) injury induced during static cold storage. (gotomydoctor.com)
Presence1
Some effects of H2S protection require the continued presence of H2S, such as ROS scavenging during ischemia. (gotomydoctor.com)
Stress1
Radionuclide studies can sometimes document asymptomatic myocardial ischemia during physical or mental stress. (rxharun.com)
Time1
Past studies have experimented with either one-time injection of NaHS solution or 30-minute incubation with H2S before ischemia. (gotomydoctor.com)