nitric oxide
- 17beta-estradiol antagonizes the down-regulation of endothelial nitric-oxide synthase and GTP cyclohydrolase I by high glucose: relevance to postmenopausal diabetic cardiovascular disease. (semanticscholar.org)
- Acetylcholine binds to muscarinic receptors on the endothelial cell surface, leading to an increase of intracellular calcium and increased nitric oxide (NO) production. (jove.com)
diseases
- This provides important information not only for the diagnosis and treatment planning of different cardiovascular diseases but also for the design of cardiovascular devices. (wisc.edu)
- Magnetic resonance imaging (MRI) is increasingly being used for fluid dynamics analyses of cardiovascular diseases, including pulmonary arterial hypertension, portal hypertension and congenital heart diseases. (wisc.edu)
- Patients with cardiovascular diseases from Guangdong province will be recruited and followed up for at least 4 years to evaluate the risk factors for cardiovascular-related mortality and d. (bioportfolio.com)
- Short telomeres have been associated with adverse lifestyle factors, cardiovascular risk factors and age-related diseases, including cardiovascular disease (CVD), myocardial infarction, atherosclerosi. (bioportfolio.com)
- For example, the risk of dying from cardiovascular diseases and/or cancer steadily declines for people after their 60s, and other causes of death predominate for seniors older than 80 years of age. (springer.com)
- Therefore, the in vivo/vitro technique described could represent a good tool to better understand how the exercise training mediates its effects on aging-related diseases, as elderly with heart failure that represents a special population in which the exercise plays an important role in the improvement of cardiovascular function, quality of life, and survival. (hindawi.com)
- These observations indicate that the heart undergoes anatomic and functional changes over aging, the interaction of which may eventually result in excessive risk for cardiovascular diseases. (hindawi.com)
- Effects of high levels of insulin, involved in many age-related diseases, on the cardiovascular function are well studied, even if conflicting data are reported in literature about the effects of insulin on myocardial contractility [ 7 ]. (hindawi.com)
- To triangulate the evidence concerning dairy products, we examined the associations of whole cow's milk consumption with cardiovascular risk factors in a non-Western setting with a different pattern of milk consumption and cardiovascular diseases from Western populations. (jove.com)
cardiac
- More recently, the use of non-linear tools, such as entropy-derived indices, have provided new insight on the cardiac autonomic regulation, revealing for instance changes in the cardiovascular complexity during REM sleep, supporting the hypothesis of a reduced capability of the cardiovascular system to deal with stress challenges. (frontiersin.org)
- Estrogen therapy, independent of timing, improves cardiac structure and function in oophorectomized mRen2.Lewis rats. (semanticscholar.org)
- Several studies have shown that advanced age is associated with abnormalities in cardiac performance and structure, such as a decline in early diastolic left ventricular filling [ 3 ] and increases in wall thickness, but also by changes in vascular and cardiac beta-receptor function [ 4 ]. (hindawi.com)
- In patients with pulmonary hypertension, inhaled epoprostenol reduces pulmonary pressure, and improves right ventricular stroke work in patients undergoing cardiac surgery. (wikipedia.org)
morbidity
- Obesity is a major health care problem and is associated with significant cardiovascular morbidity. (physiology.org)
- obesity, a major health care problem in the US, is associated with significant cardiovascular morbidity, including hypertension ( 28 ), atherosclerotic, and coronary artery disease ( 34 ), as well as the obesity hypoventilation syndrome and associated pulmonary hypertension ( 24 ). (physiology.org)
endothelial
- Tetrahydrobiopterin improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women. (semanticscholar.org)
- Since PGI2 is primarily produced in a nucleated endothelial cell, the COX inhibition by NSAID can be overcome with time by increased COX gene activation and subsequent production of more COX enzymes to catalyze the formation of PGI2. (wikipedia.org)
pathological
- However, the anatomical complexity and multidirectional nature of physiological and pathological hemodynamics makes non-invasive characterization and quantification of blood flow difficult and challenging. (wisc.edu)
- Apoptosis occurs in many physiological and pathological processes. (wikipedia.org)
coronary artery
- In elderly patients, in addition to age-related changes in function and anatomy of the cardiovascular system, a progression of coronary artery disease and organ damage associated with hypertension, diabetes, and often complicated by heart failure are found. (hindawi.com)
Mortality
- To analyze cardiovascular disease mortality and total mortality in the NAS-NRC Twin Registry using a new methodology that allowed for censored observations of outcomes, environmental covar. (bioportfolio.com)
- Shipping pollution emission associated with increased cardiovascular mortality: A time series study in Guangzhou, China. (bioportfolio.com)
- Substantial evidence has linked short-term exposure to ambient fine particulate matter (PM) with increased cardiovascular mortality, however, the specific chemical constituent and emission source resp. (bioportfolio.com)
- Cardiovascular mortality in a Western Asian country: results from the Iran Cohort Consortium. (bioportfolio.com)
- Cardiovascular mortality in Western Asia is high and still rising. (bioportfolio.com)
- Telomere length and mortality in the Ludwigshafen Risk and Cardiovascular Health study. (bioportfolio.com)
- Impact of uric acid levels on the risk of long-term cardiovascular mortality in patients with type 2 diabetes mellitus. (bioportfolio.com)
- However, the contribution of uric acid (UA) to cardiovascular mortality in diabetic patients is controversial. (bioportfolio.com)
- Uremic Pruritus is Associated with Two-Year Cardiovascular Mortality in Long Term Hemodialysis Patients. (bioportfolio.com)
- Cardiovascular and infection related deaths are the major causes of mortality in patients undergoing dia. (bioportfolio.com)
- Although overall life expectancy has improved, people with Down syndrome have even greater mortality at any age, compared with age-matched sample from the general population or compared with individuals with intellectual disabilities due to causes other than Down syndrome. (erank.tv)
- Pre-spawn mortality is a phenomenon where adult coho salmon, Oncorhynchus kisutch, die before spawning when returning to freshwater streams to spawn. (wikipedia.org)
modulation
- A key role is played by the autonomic nervous system (ANS), whose modulation regulates cardiovascular functions during sleep onset and different sleep stages. (frontiersin.org)
- Activity in this range is associated with the respiratory sinus arrhythmia (RSA), a vagally mediated modulation of heart rate such that it increases during inspiration and decreases during expiration. (wikipedia.org)
- at the University of Illinois at Urbana-Champaign demonstrated that cardiovascular organoids can be formed from ES cells through modulation of the substrate stiffness, to which they adhere. (wikipedia.org)
decreases
- During exhalation, the diaphragm relaxes, moving upward and decreases the size of the chest cavity, causing a subsequent increase in intra-thoracic pressure. (wikipedia.org)
drastically
- In postmenopausal women, the risk of diabetic cardiovascular disease drastically increases compared with that of men or premenopausal women. (semanticscholar.org)
- Blood volume also increases drastically during pregnancy. (ideafit.com)
vascular
- Prostacyclin's interactions in contrast to thromboxane (TXA2), another eicosanoid, strongly suggest a mechanism of cardiovascular homeostasis between the two hormones in relation to vascular damage. (wikipedia.org)
fluctuations
- QT interval variability (QTV) refers to the physiological phenomenon of beat-to-beat fluctuations in QT interval of electrocardiograms. (wikipedia.org)
- Ficetola also found that fluctuations in body temperature of T. carnifex decreased when body size increased. (wikipedia.org)
- Luscher noticed that color preferences shifted according to psychological and physiological fluctuations in his patients. (wikipedia.org)
variability
- Therefore, an interest on the evaluation of autonomic cardiovascular control in health and disease is growing by means of linear and non-linear heart rate variability (HRV) analyses. (frontiersin.org)
- Hypocapnia increased variability, decreased LLE and KSE, and reduced CD. (physiology.org)
- Heart rate variability (HRV) is the physiological phenomenon of variation in the time interval between heartbeats. (wikipedia.org)
vagal tone
- Generally, it is attributed to enhanced vagal tone caused by conditioning and is thus physiological. (onlinejacc.org)
- Increased vagal tone (and thus vagal action) is associated with a diminished and more variable heart rate. (wikipedia.org)
mechanism
- In order to study the mechanism of decreased blood pressure caused by an acute increase in biliary tract pressure, we observed house rabbit model of self-made caecus for changes in cardiovascular function when biliary tract pressure was increased. (semanticscholar.org)
- However, the mechanism of this phenomenon has not yet been clarified. (semanticscholar.org)
- In a recent article, Carter and Nguyen identify several genetic disorders, arguing that far from being a rare phenomenon, antagonistic pleiotropy might be a fundamental mechanism for the survival of these non-optimal alleles. (wikipedia.org)
responses
- The phenomenon of IHT is that it delivers a non-damaging training stimulus that naturally triggers a cascade of beneficial adaptive responses without adverse effects. (wikipedia.org)
- Baker-Miller Pink (#FF91AF) #FF91AF In the late 1960s, Alexander Schauss, who now operates the American Institute for Biosocial Research in Tacoma, Washington, did studies on psychological and physiological responses to the color pink. (wikipedia.org)
metabolism
- Leptin, a neuroendocrine hormone released by adipose tissue, is important in modulating obesity by signaling satiety and increasing metabolism. (physiology.org)
- These are cell atrophy, impaired metabolism (increased catabolism), reduction of the defense capacity of the organism, reducing healing processes and regeneration, degeneration of the nervous system. (erank.tv)
- Beginning around the fourth month of pregnancy, maternal metabolism increases by about 15%, rising to 20% by the time of delivery and leading to greater hunger and higher caloric intake (Hacker, Moore & Gambone 2004). (ideafit.com)
outcomes
- This paper reviews cardiovascular outcomes of GABA activation and includes own experiments on anaesthetized animals and isolated hearts. (hindawi.com)
processes
- Thus, urinary proteome changes in the elderly appear to reflect the physiological processes of aging and are particularly clearly represented in the circulatory and immune systems. (springer.com)
biological
- The biological changes that occur with increasing age play a key role in the quality of physical - motor performance. (erank.tv)
- and -λογία, -logia), environmental physiology or physiological ecology is a biological discipline that studies the adaptation of an organism's physiology to environmental conditions. (wikipedia.org)
metabolic
- Thus, physiological aging presents numerous unanswered questions, particularly with regard to changing metabolic patterns. (springer.com)
- 2012 ). Thus, diagnoses and research in which heart disease and cancer are the focus are ineffectual for half of the patients older than 80 years, and physiological aging raises many unanswered questions, particularly with regard to changing metabolic patterns. (springer.com)
- Dietary fructose is associated with metabolic syndrome and an increase in kidney weight. (physiology.org)
- This metabolic increase is essential during pregnancy to meet all of the changing needs of the various organ systems and to provide adequate fuel and nutrition to the developing fetus. (ideafit.com)
Regulation
- A key role in the physiology of sleep is played by the autonomic nervous system (ANS), whose regulation modulates cardiovascular functions during sleep onset and the transition to different sleep stages. (frontiersin.org)
function
- Comprehensive characterization and quantification of blood flow is essential for understanding the function of the cardiovascular system under normal and diseased conditions. (wisc.edu)
- In particular, the oldest group showed protein changes reflective of altered extracellular matrix turnover and declining immune function, in which changes corresponded to reported changes in cardiovascular tissue remodeling and immune disorders in the elderly. (springer.com)
- It is essential for cardiovascular function, and development and function of skeletal muscle, the retina, and the central nervous system. (wikipedia.org)
- In 2010, Mathieu Unbekandt & Jamie A. Davies demonstrated the production of renal organoids from murine fetus-derived renogenic stem cells: subsequent reports showed significant physiological function of these organoids in vitro and in vivo. (wikipedia.org)
Damage
- Is Physical Activity Able to Modify Oxidative Damage in Cardiovascular Aging? (hindawi.com)
- Damage to the left hemisphere in patients results in a marked increase in depression. (wikipedia.org)
system
- Angiotensin II (Ang II) is the principal vasoactive substance of the renin-angiotensin system (RAS), having a variety of physiological actions including vasoconstriction, aldosterone release, and cell growth. (ahajournals.org)
- The picture is however blurred in the presence of anaesthesia where both the concentration and type of anaesthetics can result in different effects on the cardiovascular system. (hindawi.com)
- In addition to CNS effects GABAergic neurons also have a significant impact on the cardiovascular system. (hindawi.com)
- The cardiovascular system responds by working more efficiently and pumping out more blood per beat to better supply tissues with oxygen. (ideafit.com)
- In early tests in 1978, Schauss observed that color, surprisingly, did affect muscle strength, either invigorating or enervating the subject, and even influenced the cardiovascular system. (wikipedia.org)
organ
- these increase with 3 more bars, that consist of secondary filaments, which create the respiratory organ. (wikipedia.org)
changes
- In conclusion, the impact of changes in GABAergic input is very difficult to predict in these settings, emphasizing the need for experiments performed in conscious animals when aiming at determining the cardiovascular effects of compounds acting on GABAergic neurons. (hindawi.com)
- To provide a foundation, the article will also discuss the hormonal and physiological changes that take place during the course of a typical 40-week pregnancy. (ideafit.com)
- Many of the physiological changes of pregnancy are due to a hormonal influx of more than 30 different hormones that are secreted throughout the gestation period (Worthington-Roberts & Williams 1997). (ideafit.com)
- Stimuli were presented over a very short period of time such that subjects were not consciously aware of the stimuli but were still able to show physiological changes. (wikipedia.org)
Estrogen
- Ablation of the estrogen binding site in the PEMT promoter region may increase risk of hepatic steatosis from choline deficiency. (wikipedia.org)
subsequent
- cAMP goes on to inhibit any undue platelet activation (in order to promote circulation) and also counteracts any increase in cytosolic calcium levels that would result from thromboxane A2 (TXA2) binding (leading to platelet activation and subsequent coagulation). (wikipedia.org)
role
- Studies have shown that the efficiency of pulmonary gas exchange is improved by RSA, suggesting that RSA may play an active physiological role. (wikipedia.org)
patients
- The U.S. Food and Drug Administration (FDA) is advising caution before prescribing the antibiotic clarithromycin (Biaxin) to patients with heart disease because of a potential increased risk of heart problems or death that can occur years later. (criticalcaremcqs.com)
- BA length, diameter and volume, and cerebral lesions were analysed by MRI/TOF-MR angiography or CT/CT angiography in 20 LOPD patients and 40 controls matching in age, sex- and cardiovascular risk factors. (springer.com)
- The diameter, length and volume of the BA were significantly increased in LOPD patients compared to controls. (springer.com)
- These patients also show a remarkable increase in lateralization towards the right hemisphere of both emotionally and non-emotional prosody rich speech. (wikipedia.org)
receptors
- Angiotensin (Ang) II exerts its important physiological functions through 2 distinct receptor subtypes, type 1 (AT 1 ) and type 2 (AT 2 ) receptors. (ahajournals.org)
- 2-9 Therefore, recent advances in studies of Ang II receptors could prove the existence of a variety of new players and targets in addition to the traditional "Ang II world" and provide a new insight into cardiovascular biology. (ahajournals.org)
- Deletion of the receptors abolished the size increase response to dietary fructose. (physiology.org)
adaptation
- Intermittent hypoxic training (IHT), also known as intermittent hypoxic therapy, is a non-invasive, drug-free technique aimed at improving human performance and well-being by way of adaptation to reduced oxygen. (wikipedia.org)
occurs
- This increased pressure inhibits venous return to the heart and thus less atrial expansion and activation of baroreceptors occurs. (wikipedia.org)
- An increase in body size also occurs where there is increased precipitation or nearby primary producers, due to the effect of increased resources on animals. (wikipedia.org)
However
- However, a number of physiological and technical issues can affect the accuracy of the results and appropriate guidelines for the technique have been published. (jove.com)
membrane
- Taurine crosses the blood-brain barrier and has been implicated in a wide array of physiological phenomena including inhibitory neurotransmission, long-term potentiation in the striatum/hippocampus, membrane stabilization,[unreliable medical source? (wikipedia.org)
- Furthermore, PC made via PEMT plays a wide range of physiological roles, utilized in choline synthesis, hepatocyte membrane structure, bile secretion, and very-low-density lipoprotein (VLDL) secretion. (wikipedia.org)
diabetes
- RSA also becomes less prominent in individuals with diabetes and cardiovascular disease. (wikipedia.org)
Aging
- Aging is a complex physiological process that poses considerable conundrums to rapidly aging societies. (springer.com)
- Aging is a complex physiological process that poses many problems and conundrums for rapidly aging societies. (springer.com)
- The theme of G.C. William's idea about antagonistic pleiotropy was that if a gene caused both increased reproduction in early life and aging in later life, then senescence would be adaptive in evolution. (wikipedia.org)
thus
- The low pKa of taurine's sulfonic acid group ensures this moiety is negatively charged in the pH ranges normally found in the intestinal tract, thus it improves the surfactant properties of the cholic acid conjugate. (wikipedia.org)
gradually
- RSA is pronounced in children, but without sufficient cardiovascular exercise it gradually disappears as a person approaches his/her teenage years. (wikipedia.org)
important
- It is important to differentiate between physiological adaptations to mild hypoxia and re-oxygenation episodes (i.e., the IHT protocol) and frequent nocturnal suffocation awakenings produced by sleep apnea, which might result in various pathologies. (wikipedia.org)
obesity
- The ob/ob mouse may, therefore, be an excellent new model for the study of the cardiovascular effects of obesity. (physiology.org)
dysfunction
- No evidence of platelet dysfunction or an increase in surgical bleeding after administration of inhaled epoprostenol has been found. (wikipedia.org)
inhalation
- It is characterized by an increased heart rate during inhalation and a diminished heart rate during exhalation. (wikipedia.org)
health
- This work was primarily supported by a Marriott Foundation Cardiovascular Fellowship (CME), National Institutes of Health R01 DK082507 (CME), as well as Georgetown University Department of Medicine internal funding. (physiology.org)
severe
- It increases with age, and is so severe as to stop compliance with drug therapy. (wikipedia.org)
effects
- The majority of well-known Ang II actions are mediated via AT 1 receptor stimulation, and angiotensin converting enzyme inhibitors (ACEI) and AT 1 receptor blockers (ARBs) have been widely used as antihypertensive drugs, with the expectation of cardiovascular protective effects. (ahajournals.org)
- The antioxidant effects could increase, decrease, or not change in relation to the exercise protocol. (hindawi.com)
- These protect them from the damaging effects of ice formation and falling rates of enzyme catalysis at low temperatures, and from enzyme denaturation and increased photorespiration at high temperatures. (wikipedia.org)
exercise
- This is a normal phenomenon, and these will become suppressed with exercise-induced increases in the sinus rate. (onlinejacc.org)
rapidly
- The technique for growing organoids has rapidly improved since the early 2010s, and it was named by The Scientist as one of the biggest scientific advancements of 2013. (wikipedia.org)
control
- There is anatomic and physiological evidence for a polyvagal control of the heart. (wikipedia.org)
temperatures
- 2010) discovered that living in colder temperatures resulted a body size increase in both male and female. (wikipedia.org)
- As temperatures fall, production of antifreeze proteins and dehydrins increases. (wikipedia.org)
- As temperatures rise, production of heat shock proteins increases. (wikipedia.org)
normal
- This, in turn, causes the normal phenomenon of pregnancy-induced anemia, a condition in which the increase in red blood cell production is not as rapid or complete as the increase in blood volume. (ideafit.com)
activity
- Physical activity increases the expression and the activity of antioxidant enzymes, with consequent reduction of ROS. (hindawi.com)
- Decreased PSNS activity or increased SNS activity will result in reduced HRV. (wikipedia.org)
- Less is known about the physiological inputs of the low frequency (LF) activity (0.04 to 0.15 Hz). (wikipedia.org)
- Andreone and Giacoma (1989) speculated that newt migration into the ponds increases after rainy days, since after rainfall, newt activity is not limited by humidity. (wikipedia.org)
heart
- Subsequently, heart rate increases. (wikipedia.org)
gene
- Pleiotropy is the phenomenon where one gene controls for more than one phenotypic trait in an organism. (wikipedia.org)
long-term
- This finding raises concerns about whether or not long‐term benefits of anti‐TGF β therapeutics improve the durability of medically reopened arteries. (physiology.org)
counteracts
- This increase in surface area counteracts the decreased oxygen available, by allowing greater oxygen uptake. (wikipedia.org)