• vascular
  • Prostacyclin's interactions in contrast to thromboxane (TXA2), another eicosanoid, strongly suggest a mechanism of cardiovascular homeostasis between the two hormones in relation to vascular damage. (wikipedia.org)
  • calcium
  • cAMP goes on to inhibit any undue platelet activation (in order to promote circulation) and also counteracts any increase in cytosolic calcium levels that would result from thromboxane A2 (TXA2) binding (leading to platelet activation and subsequent coagulation). (wikipedia.org)
  • cardiac
  • In patients with pulmonary hypertension, inhaled epoprostenol reduces pulmonary pressure, and improves right ventricular stroke work in patients undergoing cardiac surgery. (wikipedia.org)
  • health
  • This work was primarily supported by a Marriott Foundation Cardiovascular Fellowship (CME), National Institutes of Health R01 DK082507 (CME), as well as Georgetown University Department of Medicine internal funding. (physiology.org)
  • human
  • Intermittent hypoxic training (IHT), also known as intermittent hypoxic therapy, is a non-invasive, drug-free technique aimed at improving human performance and well-being by way of adaptation to reduced oxygen. (wikipedia.org)
  • result
  • It is important to differentiate between physiological adaptations to mild hypoxia and re-oxygenation episodes (i.e., the IHT protocol) and frequent nocturnal suffocation awakenings produced by sleep apnea, which might result in various pathologies. (wikipedia.org)