• Listeria
  • Although L. monocytogenes is actively motile by means of peritrichous flagella at room temperature (20−25 °C), the organism does not synthesize flagella at body temperatures (37 °C). The genus Listeria belongs to the class Bacilli and the order Bacillales, which also includes Bacillus and Staphylococcus. (wikipedia.org)
  • Candida
  • The formation of NLRP3 inflammasome can be activated by PAMPs such as microbial toxins (for example alpha-toxin Staphylococcus aureus) or whole pathogens, for instance Candida albicans, Saccharomyces cerevisiae, Sendai virus, Influenza. (wikipedia.org)
  • Attacking and lysing these cells allows the pathogen to harm the host organism, and also provides it with a source of iron from the lysed hemoglobin, like the fungus Candida albicans. (wikipedia.org)
  • complement
  • A gene cluster responsible for secretion of the polysaccharide capsule has been identified and shown to inhibit the antibiotic effect of complement when grown on ascites fluid. (wikipedia.org)
  • Because of its role in the innate immune system classical complement has been implicated in a number of pathogen related disorders. (wikipedia.org)
  • Complement is responsible for immune inflammatory response in adipose tissues which has been implicated in the development of obesity. (wikipedia.org)
  • This is important for targeting the virus in its intracellular phase because the antibodies specific to the synthetic peptides can trigger the classical complement pathway and induce the death of HIV infected cells. (wikipedia.org)
  • coli
  • E. coli are also responsible for a majority of cases of urinary tract infections. (wikipedia.org)
  • E. coli is the most widely studied prokaryotic model organism, and an important species in the fields of biotechnology and microbiology, where it has served as the host organism for the majority of work with recombinant DNA. (wikipedia.org)
  • The acidic capsular polysaccharide (CPS) is a thick, mucous-like, layer of polysaccharide that surrounds some pathogen E. coli. (wikipedia.org)
  • proteins
  • Staphylococcus aureus surface proteins interfere with neutrophil mobilization and activation, while others inhibit neutrophil serine proteases. (embopress.org)
  • ADEP binding induces ClpP proteolytic activation that leads to the proteins degradation in the cell, especially nascent proteins and the Ftsz protein which is an important protein in cell division. (wikipedia.org)
  • These chaperone proteins are responsible for hydrolyzing ATP to ADP, harnessing the energy, and then taking folded proteins and unfolding them. (wikipedia.org)
  • humans
  • In humans, the pathogen has been isolated in intravascular and indwelling catheters and associated with conditions including urinary tract infections, septicemia, conjunctivitis , and endocarditis. (healthcaremagic.com)
  • human
  • Immunology research is important for understanding the mechanisms underlying the defense of human body and to develop drugs for immunological diseases and maintain health. (wikipedia.org)
  • resistance
  • Recently, it has been found that this class of compounds might be also important as chemotherapeutic agents, especially against the proliferation of various cancer cells, including those displaying multi-drug resistance and against cancer stem cells (CSCs). (pjmonline.org)
  • To overcome this problem, knowledge of the pathogenesis, antibiotic resistance mechanisms, and prospective treatment options of A. baumannii is important. (wikipedia.org)
  • potentially
  • Recently, studies describing potentially important biological and pharmacological activities of NAC have stimulated interests in using NAC-based therapeutics for oral health care. (hindawi.com)
  • severity
  • These wide variations in cost of care reflect the complex nature of SSIs, which may substantially differ in severity depending on the causative pathogen, type of surgical procedure performed, patient's underlying health condition, and other factors. (clinicaladvisor.com)
  • fibrinogen
  • This protein domain is of huge significance since it binds to fibrinogen, a glycoprotein involved in important processes such as haemostasis and coagulation. (wikipedia.org)
  • 2002). "A novel variant of the immunoglobulin fold in surface adhesins of Staphylococcus aureus: crystal structure of the fibrinogen-binding MSCRAMM, clumping factor A". EMBO J. 21 (24): 6660-72. (wikipedia.org)
  • microbial
  • Another important role that microbial exoenzymes serve is in the natural ecology and bioremediation of terrestrial and marine environments. (wikipedia.org)