• MCPyV in tumor cell genomes, tumor-associated mutations search Ethics Board, Halifax, Nova Scotia, Canada, and in the large T-antigen (T-ag) gene, and large T-ag expres- by the Baylor College of Medicine Institutional Review sion in tumors suggest that MCPyV is not only associated Board, Houston. (cdc.gov)
  • In gliomas and colorectal carcinomas, aberrant methylation was detected in 40% of the tumors, whereas in non-small cell lung carcinomas, lymphomas, and head and neck carcinomas, this alteration was found in 25% of the tumors. (aacrjournals.org)
  • 15% tumor cells harboring split signals to determine ALK -positive tumors. (biomedcentral.com)
  • My research interests comprise cutaneous tumors with emphasis in lymphomas and melanoma. (mdanderson.org)
  • In lymphomas I have conducted studies in rare aggressive primary cutaneous tumors such as gamma/delta T cell lymphoma (expanding the description of the epidermotropic variant) as well as more indolent entities such as lymphomatoid papulosis (type D) and CD4-positive small to medium size T cell lymphoproliferative disorders. (mdanderson.org)
  • Besides, many studies have proved that ethanol extract from radix of Actinidia chinensis (EERAC) has an obviously curative effect on several types of tumors including hepatocellular carcinoma and lung cancer, [ 15 - 17 ]. (jcancer.org)
  • 1 The most frequent primary tumor types of anterior mediastinal masses are thymic tumors and lymphoma, with approximate proportions of 35% and 25% among mediastinal lesions, respectively. (allenpress.com)
  • Twenty-five percent of all lung tumors belong to the group of neuroendocrine tumors [ 2 ] including typical carcinoid (TC) and atypical carcinoid (AC), large-cell neuroendocrine cancer (LCNEC), and small-cell lung cancer (SCLC). (oncotarget.com)
  • In the past decade, many clinical trials have been investigating anti-CTLA-4 as well as anti-programmed cell death protein 1 (PD-1) therapies in various solid tumors, including HCC. (stanford.edu)
  • Main Outcome(s) and Measure(s): The primary study outcome was to determine the prognostic value of p53 Abs from a large population of patients with solid tumors, as determined before data collection. (stanford.edu)
  • Poorly differentiated tumors are called anaplastic. (lecturio.com)
  • Recently, the treatment of newly diagnosed anaplastic glioma (AG) has changed, particularly in patients with 1p19q codeleted tumors. (surgicalneurologyint.com)
  • It is thought that leiomyoma is the result of either transformation of normal uterine muscle cells into abnormal cells through somatic mutations , or through the growth of abnormal uterine muscle cells into tumors. (wikidoc.org)
  • There are two clinical types of lung cancer: non-small cell lung carcinoma (NSCLC), which accounts for 85% of all cases, and small cell lung carcinoma (SCLC) [ 1 , 3 ]. (oncotarget.com)
  • Furthermore, upregulation of PD-L1 by cancer cells results in cancer invasion and correlates with poor prognostic outcomes in breast, gastric, meningioma, non-small-cell lung carcinoma (NSCLC) and soft-tissue sarcoma patients [9,26-29]. (studylib.net)
  • Anaplastic lymphoma kinase (ALK) also known as ALK tyrosine kinase receptor or CD246 (cluster of differentiation 246) is an enzyme that in humans is encoded by the ALK gene. (wikipedia.org)
  • Anaplastic lymphoma kinase (ALK) was originally discovered in 1994 in anaplastic large-cell lymphoma (ALCL) cells. (wikipedia.org)
  • The translocation creates a fusion gene consisting of the ALK (anaplastic lymphoma kinase) gene and the nucleophosmin (NPM) gene: the 3' half of ALK, derived from chromosome 2 and coding for the catalytic domain, is fused to the 5' portion of NPM from chromosome 5. (wikipedia.org)
  • EGFR (epidermal growth factor receptor), ALK (anaplastic lymphoma receptor tyrosine kinase), RET (ret proto-oncogene receptor tyrosine kinase), and BRAF (B-Raf proto-oncogene, serine/threonine kinase) are well-identified oncogenic driver mutations in lung cancer, and are targets for therapeutic application. (oncotarget.com)
  • The most common histological change is the switch from adenocarcinoma (AdenoCa) to small cell carcinoma (SCC) against to tyrosine kinase inhibitors (TKI). (e-crt.org)
  • Despite dramatic response to tyrosine kinase inhibitors (TKI), drug resistance develops in many non-small cell carcinomas (NSCC) harboring epidermal growth factor receptor ( EGFR ) mutation within a median interval of a year [ 1 , 2 ]. (e-crt.org)
  • Over 80 cases of anaplastic lymphoma kinase-negative anaplastic large cell lymphoma have been reported in patients with silicone breast implants and have been accepted as a new clinical entity. (biomedcentral.com)
  • Importantly, it appears that orexigenic neuropeptide Y agouti connected protein neurons come to be lively inside a low ROS situation, which can be the opposite of anorexigenic VEGFR tyrosine kinase inhibitor pro opiomelanocortin cocaine and amphetamine regulated transcript cells, which appear to rely a lot more on glucose and are much more lively at increased ROS levels. (wnt-signaling.com)
  • Renal cell carcinoma (RCC) incidence has increased over the past two decades. (hindawi.com)
  • Renal cell carcinoma (RCC) accounts for approximately 3% of human malignancies, and its incidence appears to be increasing globally [ 1 ]. (hindawi.com)
  • 25% of all lung cancer cases are neuroendocrine (NELC) including typical (TC) and atypical carcinoid (AC), large-cell neuroendocrine (LCNEC) and small cell lung cancer (SCLC). (oncotarget.com)
  • They can arise everywhere, since neuroendocrine cells are virtually distributed in each organ. (springeropen.com)
  • The second group includes large cell neuroendocrine carcinoma (LCNEC) and small cell lung cancer (SCLC). (springeropen.com)
  • Later, bronchoscopy incidentally revealed the patient to have an endobronchial lesion that turned out to be mixed small and large cell neuroendocrine lung cancer. (biomedcentral.com)
  • We identified a unique case of triple SLC, including adenocarcinoma, squamous cell carcinoma, and mixed small and large cell neuroendocrine carcinoma, which has poor prognostic implications. (biomedcentral.com)
  • Herein, we present a case of coexisting neuroendocrine carcinoma and conventional adenocarcinoma (collision tumor) in the ampulla of Vater, which has seldom been reported in the literature. (koreamed.org)
  • Pathologically, sections on the ampulla of Vater showed conventional ductal adenocarcinoma extended and collided with poorly differentiated neuroendocrine carcinoma. (koreamed.org)
  • In conclusion, we hereby presented a case of coexisting neuroendocrine carcinoma and conventional adenocarcinoma in the ampulla of Vater. (koreamed.org)
  • Lesions with larger particles might be visible on dental radiographs. (medscape.com)
  • These lesions are microscopically characterized by a diffuse, pseudoinvasive, mixed inflammatory reaction that includes large mononuclear cells, numerous eosinophils, and T cells. (medscape.com)
  • These lesions have been misdiagnosed as non-Hodgkin lymphoma and squamous cell carcinoma, and unnecessary radical treatment may result. (medscape.com)
  • metastasis from lungs, kidneys, breasts via blood, lymphoma or anaplastic carcinoma in benign lymphoepithelial lesions (Sjogren's syndrome, Mikulicz' disease) and Kimura's disease( 1 ). (ispub.com)
  • Generalized Multinucleate Cell Angiohistiocytoma: Histopathological and Immunohistochemical Analyses of 10 Lesions. (jefferson.edu)
  • Inhibition of the oncogenic fusion-gene EML4-ALK is a current first-line approach for patients with stage IV non-small cell lung cancer. (biomedcentral.com)
  • Flavonoids in Ageratum conyzoides and Chinese herbal formulas Miao-Yi-Ai-Tang have presented significant inhibition on cervical carcinoma and lung cancer, respectively [ 9 ]. (jcancer.org)
  • She was diagnosed with non-small cell lung cancer (NSCLC) with bone metastasis and pneumocystis pneumonia (PCP). (biomedcentral.com)
  • Non-small cell lung cancer (NSCLC) is the most common type of lung cancer in pregnant women, accounting for approximately 85% of all gestational cancers [ 6 ]. (biomedcentral.com)
  • Knockdown of GPR171 also inhibited migration and invasion of the lung cancer cell lines. (oncotarget.com)
  • Notably, inhibition of GPR171 synergistically enhanced the tumoricidal activity of an epidermal growth factor receptor (EGFR) inhibitor in lung cancer cells. (oncotarget.com)
  • We aimed to identify transportins that are overexpressed in Non-small cell lung cancer (NSCLC) and might be targeted to slow the tumor growth. (researchsquare.com)
  • After undergoing complete resection of non-small cell lung cancer, patients have a 1-2% risk per patient per year that of developing another lung cancer [ 5 ]. (biomedcentral.com)
  • The discovery of targetable genomic alterations has revolutionized the field of personalized medicine in non-small cell lung cancer (NSCLC). (gotoper.com)
  • Recurrent mutations in proto-oncogenes comprise a large proportion of therapeutically targetable alterations in lung cancer. (gotoper.com)
  • EGFR mutations in non-small cell lung cancer (NSCLC) were first discovered in 2004 and are present in 10% to 15% of Caucasian patients with advanced disease. (gotoper.com)
  • Cell proliferation, migration, and invasion were measured with cell counting kit-8 (CCK-8), wound healing, and transwell assays. (jcancer.org)
  • The repair process is finalised by polymerase δ and its cofactors proliferation cell nuclear antigen (PCNA) and replication factor C (RFC), which fill in the single-stranded gap. (bmj.com)
  • Depletion of GPR171 with an anti-GPR171 antibody decreased proliferation of lung carcinoma cells and attenuated tumor progression in a mouse xenograft model. (oncotarget.com)
  • An aberrant miRNA expression could contribute to cancer development and progression [ 6 , 7 ] and could affect their target genes that are involved in many biological processes, such as cell differentiation, proliferation, apoptosis, metabolism, and development [ 8 ]. (hindawi.com)
  • The gain- and loss-of-function assays indicated that CSE1L promoted NSCLC cells proliferation and inhibits cells apoptosis. (researchsquare.com)
  • CSE1L promotes proliferation of NSCLC cells by activating the MAPK signaling pathway and inhibiting apoptosis in coordination with P65. (researchsquare.com)
  • Export and import of mRNA and specific proteins from the nucleus is a key step in intracellular signaling and can lead to cell proliferation or apoptosis. (researchsquare.com)
  • Immunohistochemical evaluation revealed the presence of tumour cells that were positive for B-cell markers with a high proliferation rate (CD20, CD10 and CD79a) (Figure 3 and 4 ). (biomedcentral.com)
  • Hematoxylin and eosin-stained sections (original magnifications X20, X100 and X400) show a lymphoid proliferation of small B-cells with a widely monotonous growth pattern, suggestive for high-grade B-cell lymphoma. (biomedcentral.com)
  • Knockdown of KDM1B inhibits cell proliferation and induces apoptosis of pancreatic cancer cells. (cancerindex.org)
  • On the other hand, the proliferation of oncolytic viruses into target cells and subsequent recognition of viral elements by pattern recognition receptors (PRRs) such as toll-like receptors can positively affect the development of the innate and adaptive immune responses against tumor cells (Fig. 1 ) [ 6 ]. (biomedcentral.com)
  • To evaluate the expression of E-cadherin (E-cad) in oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC). (ijpmonline.org)
  • Immunohistochemistry was used to detect E-cad expression in 20 cases each of normal oral mucosa, oral epithelial dysplasia and squamous cell carcinoma. (ijpmonline.org)
  • The adaptation of cells to hypoxia appears to be mediated via hypoxia inducible factor-1α (HIF-1α) which is also said to be associated with malignant transformation of epithelial cells in various other carcinomas like prostate and cervical carcinoma. (ijpmonline.org)
  • Breast cancer Breast cancer Breast cancer is a disease characterized by malignant transformation of the epithelial cells of the breast. (lecturio.com)
  • The term neoplasm includes both benign and malignant "new growths) A carcinoma is a malignant neoplasm of epithelial cells. (imperial.ac.uk)
  • After treatment with TKI and immunotherapy, an EGFR (epidermal growth factor receptor)-mutant AdenoCa changed to squamous cell carcinoma (SqCa). (e-crt.org)
  • He had recently been diagnosed with adenocarcinoma in the right upper lobe, with a poorly differentiated carcinoma favoring squamous cell cancer based on bronchoalveolar lavage of the right lower lobe for which treatment was started. (biomedcentral.com)
  • We observed a significant decrease in E-cad expression from dysplasia to poorly differentiated squamous cell carcinoma suggesting that loss of expression of E-cad is closely related to carcinoma. (ijpmonline.org)
  • 15 In squamous cell lung cancers, a variety of actionable alterations also have been discovered, 4 including DDR2 , PIK3CA , PTEN , AKT , KEAP1 , and NFE2L2 mutations. (gotoper.com)
  • what causes squamous cell carcinoma? (imperial.ac.uk)
  • It includes adenocarcinomas and squamous cell carcinoma. (imperial.ac.uk)
  • In this study, we investigated the presence of Merkel cell polyomavirus (MCPyV) was fi rst described MCPyV in benign lymph nodes and malignant lymphomas in 2008 ( 1 ) as a new human virus associated with in patients from Canada. (cdc.gov)
  • The area of research for our group is malignant lymphomas - all possible aspects, aiming for the improvement of the quality of life and survival of these patients. (lu.se)
  • The expression level of CSE1L was detected in both NSCLC cells and clinical samples. (researchsquare.com)
  • RNA-seq results indicated that CSE1L activated the MAPK signaling pathway in NSCLC cells by increasing activity of P65. (researchsquare.com)
  • we found that EERAC inhibited the cell viability, migration, and invasion of SW480 cells in a concentration dependent manner, but promoted apoptosis and the cell percentage in S phase significantly. (jcancer.org)
  • ATC cells are less likely to stain positive for certain markers, including thyroid transcription factor 1 (TTF1) or PAX-8, and do not typically stain positive for thyroglobulin in the anaplastic component of the tumor. (klarity.health)
  • e The pattern listed is for the spindled cell component of the tumor. (basicmedicalkey.com)
  • Phenotypic change into small cell carcinoma (SCC) is a resistance mechanism in NSCC treated with TKI, and small cell transformation occurs 3% to 14% of patients with EGFR mutations [ 3 , 4 ]. (e-crt.org)
  • The 2;5 chromosomal translocation is associated with approximately 60% of anaplastic large-cell lymphomas (ALCLs), type ALK-positive anaplastic large cell lymphoma and very rare cases of ALCL type primary cutaneous anaplastic large cell lymphoma. (wikipedia.org)
  • Expression of p40 in Primary Cutaneous Mucinous Carcinoma Versus Primary Mucinous Carcinomas of the Breast and Colon. (jefferson.edu)
  • While normal thyrocytes were detected in thyroid gland, atypical lymphoid cells showing diffuse infiltration in thyroid tissue were observed in the nodule, which were stained diffuse, strongly positive for CD20 and BcL and negative for CD45 RO. (endocrine-abstracts.org)
  • In the lymph node, diffusely infiltrating atypical lymphoid cells with similar immunohistochemical staining properties were observed. (endocrine-abstracts.org)
  • Follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) with concurrent BCL2 and IRF4 rearrangements are rare. (qxmd.com)
  • Melanin may also be seen in the connective tissue near the basal cell layer, as shown below. (medscape.com)
  • Also included in our study were 157 non- ing, stringent precautions were taken to avoid cross-con- lymphoma frozen tissue specimens, including 110 benign tamination between samples. (cdc.gov)
  • The diagnosis of ATC is usually made by examining cells taken from a fine-needle aspiration (FNA) biopsy or tissue taken from a large-needle or surgical biopsy. (klarity.health)
  • The diagnosis of malignant lymphoma was established after bilateral adnexectomy and histological study of the excised tissue. (biomedcentral.com)
  • A histological examination of the capsule tissue showed an extensive lymphohistiocytic/giant cell foreign body reaction suggestive of autoimmune/inflammatory syndrome induced by adjuvants. (biomedcentral.com)
  • A normal interphase cell without translocation of this locus shows yellow fusions signals whereas separation of signals (a split signal) indicates translocation/inversion. (biomedcentral.com)
  • Diffuse large B-cell lymphoma cells showing CD20 involvement were seen in cytological specimens. (endocrine-abstracts.org)
  • We introduce the case in order to emphasize that infiltration of diffuse large B-cell lymphoma should be recalled with instantaneous enlargement of nodules known to be benign previously, and when cytological specimen is uncertain, immunohistochemical staining should be performed for differential diagnosis. (endocrine-abstracts.org)
  • An ovarian involvement by non-Hodgkin lymphoma (NHL) may include one of the four subtypes of lymphoma: diffuse large B-cell lymphoma, Burkitt's lymphoma (BL), lymphoblastic lymphoma or anaplastic large cell lymphoma. (biomedcentral.com)
  • CT scan of mediastinum shows diffuse lymphatic swelling (arrow) over right supraclavicular (A) , pre-vascular (B-D) and aortopulmonary (C) station with inhomogeneous enhancing after contrast media, suggestive for lymphoma. (biomedcentral.com)
  • As cytomorphological appearance was consistent with anaplastic carcinoma in ultrasonography-guided aspiration biopsies of thyroid nodule and lymphadenopathy, immunohistochemical staining was performed for differential diagnosis of lymphoma. (endocrine-abstracts.org)
  • Hepatocellular carcinoma (HCC) is one of the most common and fatal malignancies with an alarming trend all around the world. (stanford.edu)
  • The antibody is useful for studying the phenomenon of cell death by apoptosis as a pathogenic mechanism of numerous pathologies: nerve damage, neurodegenerative diseases, cardiovascular diseases, autoimmune diseases, AIDS and malignancies. (samatashkhis.com)
  • Merkel cell carcinoma (MCC), an uncommon but aggressive form of skin cancer. (cdc.gov)
  • In addition, cytoplasmic vacuoles are not uncommon in large cell lymphomas involving body cavities. (cytojournal.com)
  • A histopathological examination revealed a high grade B-cell ovarian lymphoma. (biomedcentral.com)
  • On microscopic histopathological analysis, elongated and spindle-shaped cells with a cigar-shaped nucleus are characteristic findings of leiomyoma. (wikidoc.org)
  • Loss of expression is rarely due to deletion, mutation, or rearrangement of the MGMT gene, but methylation of discrete regions of the CpG island of MGMT has been associated with the silencing of the gene in cell lines. (aacrjournals.org)
  • It is unclear whether such cases should be classified as large B- cell lymphoma with IRF4 rearrangement or FL/DLBCL-not otherwise specified. (qxmd.com)
  • How Reliable Are Gene Expression-Based and Immunohistochemical Biomarkers Assessed on a Core-Needle Biopsy? (lu.se)
  • However, we can altogether not rule out a benign lesion as in large benign tumours, the nerve is often stretched around the mass thereby accounting for paresthesia, paresis and the tense parotid fascia leads to pain( 2 ) necessitating further investigations. (ispub.com)
  • Ab-3 shows no reaction with a variety of normal tissues .CEA is not found in benign glands, stroma, or malignant prostatic cells. (samatashkhis.com)
  • These fi ndings suggest that in human lymphoid tissues, blood cells, and lymphomas the lymphoid system plays a role in MCPyV infection and ( 17 - 20 ). (cdc.gov)
  • DNA was extracted from frozen tissues by lysis buffer/ criteria by using morphologic and immunohistochemical proteinase K treatment and phenol-chloroform extraction evaluation ( 21 ). (cdc.gov)
  • MGMT expression is decreased in some tumor tissues, and lack of activity has been observed in some cell lines. (aacrjournals.org)
  • All normal tissues and expressing cancer cell lines were unmethylated, whereas nonexpressing cancer cell lines were methylated. (aacrjournals.org)
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
  • Immunostaining of clinical samples indicated that GPR171 was overexpressed in 46.8% of lung carcinoma tissues. (oncotarget.com)
  • Differentiating between low-grade lymphoma and reactive lymphocytes is often difficult by morphology alone as reactive lymphoid cells may acquire activation morphology from being exposed to different cytokines within the body fluid. (cytojournal.com)
  • although it is derived from cells of the renal tubular epithelium, it has several histological subtypes which differ in their clinical outcome and biological features. (hindawi.com)
  • The need for other histochemical or immunohistochemical stains is determined by the clinical circumstances and the preliminary findings. (bmj.com)
  • Thirteen years ago, we pointed out that ovarian transitional cell carcinomas (TCCs) and conventional high-grade serous carcinomas (HGSC) had similar genetic alterations and clinical behavior. (qxmd.com)
  • 2. Clinical epidemiology - using data from the Swedish Lymphoma Registry to provide clinically useful real world data on treatment and prognosis, in many cases in collaboration with Nordic colleagues. (lu.se)
  • Anaplastic thyroid cancer cells typically have morphological patterns of spindle cell, pleomorphic giant cell, and/or squamoid, and may have a mix of these patterns. (klarity.health)
  • In contrary, tumor cells have evolved immune escape mechanisms whereby overexpression of PD-L1 induces anergy and/or apoptosis of PD-1 positive T cells by interfering with T cell receptor signal transduction. (studylib.net)
  • Consequently, it was shown by others that tumor cells also expressed MHC-I and presented short tumor-associated peptides to immune cells [6]. (studylib.net)
  • However, tumor cells can evade host's immune surveillance using a number of protective mechanisms, including downregulation of MHC-I molecules, secretion of anti-inflammatory cytokines, in other words, TGF-β and IL-10, secretion of immunosuppressive factors, VEGF, upregulation of PD-L1 and downregulation of co-stimulatory molecules thereby preventing activation of T cells, resulting in cancer invasion. (studylib.net)
  • The binding of T cells expressing PD-1 and tumor cells expressing PD-L1 initiates an array of inhibitory signals resulting in reduced function and/or apoptosis of T cells [8,11] providing a mechanism for tumor cell evasion of host's immune surveillance [12-14]. (studylib.net)
  • Oncolytic viruses (OVs) specifically induce cancer cells death by infection of and spreading on tumor cells through different mechanisms such as direct lysis effect or adjacent cells fusion. (biomedcentral.com)
  • The ability of OVs to selectively infect tumor cells is mainly associated with the disruption of type-I interferon pathway, which represents the first line of defense against viral infections. (biomedcentral.com)
  • Schematic illustration of the multimodality role of virotheranostics in treatment and tracking of tumor cells. (biomedcentral.com)
  • In melanoma, i have focused in acral lentiginous melanoma for which we described KIT mutation and protein expression status in a large series of cases and described TERT amplification in progression to metastasis. (mdanderson.org)
  • In general, hematolymphoid cells manifest as dyshesive cells in cytological specimens. (cytojournal.com)
  • and cell differentiation ( SOX2 and TGFB3 ) as well as immunohistochemical assay for VEGFA, TP53, Bcl2, TGFB1, and Ki67 protein expression have been performed in 85 FFPE RCC tumor specimens. (hindawi.com)
  • Microscopic examination of tumor Tumor Inflammation cells after surgery or biopsy Biopsy Removal and pathologic examination of specimens from the living body. (lecturio.com)
  • Immunohistochemical data for molecular genetic alterations are used in addition to histology. (lecturio.com)
  • Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). (samatashkhis.com)
  • Large cell lymphoma and leukemia cells tend to have large size nuclei, less mature chromatin, and visible nucleoli with and without cytoplasmic vacuoles. (cytojournal.com)
  • Primary non-Hodgkin's lymphoma of the ovary is a rare occurrence. (biomedcentral.com)
  • Non Hodgkins Lymphoma represents the fifth primary reason behind cancer deaths inside the United states of america as well as 2nd quickest increasing cancer in terms of mortality. (wnt-signaling.com)
  • Histologic subtypes of medulloblastoma include: (1) desmoplastic/nodular type, (2) medulloblastoma with extensive nodularity, and (3) large-cell/anaplastic medulloblastoma. (medscape.com)
  • MEN1 maps on chromosome 11 and encodes for menina, a nuclear protein involved in cell replication, DNA repair and transcription process. (springeropen.com)
  • Compared with conventional cancer treatments, the main advantage of oncolytic virotherapy is its tumor-selective replication followed by the destruction of malignant cells without damaging healthy cells. (biomedcentral.com)
  • Anaplastic thyroid cancer (ATC) is a rare and highly aggressive form of thyroid cancer. (klarity.health)
  • The exact cause of Anaplastic Thyroid Cancer (ATC) is unknown, but certain risk factors have been identified. (klarity.health)
  • If you are suspected of having anaplastic thyroid cancer (ATC), your doctor will conduct a physical exam and several tests to make a diagnosis. (klarity.health)
  • Theree are other types of cancer that can look similar to anaplastic thyroid cancer under the microscope, but have different treatments and prognoses. (klarity.health)
  • In large cell lymphoma and leukemia cells involvement of body fluid this concept becomes less challenging. (cytojournal.com)
  • HN - 2008 BX - Von Ebner's Glands MH - Cumulus Cells UI - D054885 MN - A05.360.319.114.630.535.200.500 MN - A06.407.312.497.535.300.500 MN - A11.436.300.500 MS - The granulosa cells of the cumulus oophorus which surround the OVUM in the GRAAFIAN FOLLICLE. (bvsalud.org)
  • The antitumor effect of ethanol extracted from radix of Actinidia chinensis (EERAC) were identified in human colon cancer cells, but the underlying mechanism remains unclear. (jcancer.org)
  • Cancer cells can utilize the transportins into and out of the nucleus to stimulate tumor growth and to effectively evade apoptotic mechanisms. (researchsquare.com)
  • Anaplastic cancer is a rare disease, with an age-adjusted annual incidence of approximately one to two cases per million individuals. (klarity.health)
  • However, for cancer prevention, the elimination or inactivation of mutated cells is debated on whether this is a prime function of the immune system. (studylib.net)
  • In fact, cancer cells, in particular renal and breast cells express high levels of PD-L1 leading to poor patient survival [15,16]. (studylib.net)
  • Although chemotherapy is accepted as standard treatment, large scale of patients suffers from the severe side effects, and drug resistance is commonly observed after long-term treatment. (jcancer.org)
  • To the best of our knowledge, an intravascular large B-cell lymphoma associated with a silicone breast implant has not been reported previously. (biomedcentral.com)
  • The genetic background of our patient with silicone breast implants might have predisposed her to three rare and difficult to diagnose syndromes/diseases: macrophage activation syndrome/hemophagocytic lymphohistiocytosis, autoimmune/inflammatory syndrome induced by adjuvants, and intravascular large B-cell lymphoma. (biomedcentral.com)
  • Flies lacking the receptor die due to failure of founder cell specification in embryonic visceral muscle. (wikipedia.org)
  • Cytological examination of the peritoneal washing was negative for neoplastic cells. (biomedcentral.com)