• immune system
  • Binding of the immunoglobulins to a microbe can have immediate effects such as blocking invasion and it can mobilize other components of the immune system to destroy or otherwise inactivate the microbes, thereby providing protection against infectious diseases. (wikipedia.org)
  • Therapy
  • Human immunoglobulin therapy first occurred in the 1930s and a formulation for injection into a vein was approved for medical use in the United States in 1981. (wikipedia.org)
  • Immunoglobulin therapy is also used in some treatment protocols for secondary immunodeficiencies such as human immunodeficiency virus (HIV), some autoimmune disorders (such as immune thrombocytopenia and Kawasaki disease), some neurological diseases (multifocal motor neuropathy, stiff person syndrome, multiple sclerosis and myasthenia gravis) some acute infections and some complications of organ transplantation. (wikipedia.org)
  • Different national bodies and medical associations have established varying standards for the use of immunoglobulin therapy. (wikipedia.org)
  • often
  • If you are suffering from cirrhosis of the liver or rheumatoid arthritis and therefore you have high levels of IgA, will you ever need to replace or get any more immunoglobulin via intravenously (more often said as receiving immunoglobulin via iv) or maybe have an immunoglobulin infusion? (wisegeek.com)
  • IgY is often mislabelled as Immunoglobulin G (IgG) in older literature, and sometimes even in commercial product catalogues, due to its functional similarity to mammalian IgG and Immunoglobulin E (IgE). (wikipedia.org)
  • expression
  • Genetic rearrangements occur during the maturation of B lymphocytes, eventually resulting in the surface expression of both immunoglobulin M (IgM) and IgD on mature B cells. (medscape.com)
  • health
  • Someone experiencing health problems may have their immunoglobulin levels tested. (wisegeek.com)
  • Immunoglobulin levels are very helpful when trying to pinpoint a health concern, but are not the only tests used to diagnose these conditions. (wisegeek.com)
  • The United Kingdom's National Health Service recommending routine use of immunoglobulin for a variety of conditions including primary immunodeficiencies and a number of other conditions, but recommending against the use of immunoglobulin in sepsis (unless a specific toxin has been identified), multiple sclerosis, neonatal sepsis, and pediatric HIV. (wikipedia.org)
  • variety
  • Inasmuch as the V domains can occur in a nearly unlimited variety of amino acid sequences, immunoglobulins collectively have the potential of binding to virtually any molecular structure. (wikipedia.org)
  • specific
  • These conditions include primary immunodeficiency, idiopathic thrombocytopenic purpura, chronic inflammatory demyelinating polyneuropathy, Kawasaki disease, certain cases of HIV/AIDS and measles, Guillain-BarrĂ© syndrome, and in certain other infections when a more specific immunoglobulin is not available. (wikipedia.org)
  • cell
  • A B-cell immunoglobulin gene rearrangement test evaluates the cells in a person's sample to determine whether the majority of B-cell rearrangement profiles are diverse or identical. (labtestsonline.org)
  • Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils. (medscape.com)