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Rotavirus VaccinesRotavirusRotavirus InfectionsGastroenteritisIntussusceptionVaccines, AttenuatedVaccinesViral VaccinesVaccinationDiarrheaVaccines, InactivatedDiarrhea, InfantileVaccines, CombinedImmunization ScheduleReassortant VirusesAntibodies, ViralVaccines, SyntheticVaccines, DNACapsid ProteinsFecesSafety-Based Drug WithdrawalsBacterial VaccinesImmunityImmunization ProgramsNicaraguaAIDS VaccinesAntigens, ViralImmunity, InnateImmunity, CellularInfant, NewbornImmunoglobulin AVaccines, SubunitVaccine PotencyVaccines, ConjugateHospitalizationProduct Surveillance, PostmarketingAdministration, OralLatin AmericaDiphtheria-Tetanus-Pertussis VaccineMalaria VaccinesImmunization, SecondaryPoliovirus Vaccine, OralVirus SheddingDeveloped CountriesNeutralization TestsSerotypingVaccines, Live, UnattenuatedPapillomavirus VaccinesGerm-Free LifeSeasonsMeningococcal VaccinesUzbekistanDeveloping CountriesMeasles VaccineEnzyme-Linked Immunosorbent AssayHepatitis B VaccinesImmunoglobulin GPertussis VaccineImmunizationMice, Inbred BALB CBCG VaccineImmunity, MucosalGenotypeClinical Trials as TopicUnited StatesMexicoImmunity, HumoralAdjuvants, ImmunologicHaemophilus VaccinesPhiladelphiaIncidenceCholera VaccinesPoliovirus Vaccine, InactivatedHospitals, PediatricRabies VaccinesAdaptive ImmunityCost-Benefit AnalysisAdverse Drug Reaction Reporting SystemsSmallpox VaccineMolecular Sequence DataToxins, BiologicalTyphoid-Paratyphoid VaccinesTuberculosis VaccinesCapsidDouble-Blind MethodIndiaImmunity, Maternally-AcquiredChickenpox VaccineDose-Response Relationship, ImmunologicMalawiCattlePlacebosAntibodies, BacterialMumps VaccinePoliomyelitisCost of IllnessMeasles-Mumps-Rubella VaccineHepatitis A VaccinesAntibody FormationViral Nonstructural Proteins
VaccinationInfectionRotarixInfantsRotaTeqDevelop immunityStrainsVaccinationsImmunizationInfectionsViralHerdAntibodiesDiseasesImmunogenicityPolio vaccinePrevent rotavirusPentavalent vaccineDosesStrainThird dose of rotavirusInfluenzaTetanusMeaslesDiarrheaVaricellaPertussisDiarrhoeaDose of the vaccineChickenpoxEffectivenessIllnessTypes of vaccinesSkipMucosalVirusesAnti-vaccineDTaPSerotypesChildhoodCause of severeBacteriaInfectiousMaternal immunityEfficacyTetravalent rhesus1998Quadrivalent vaccineWithdrawn from the marketReassortantDeathsNewbornsProtectiveImmune systemType of vaccineChildrenLive but weakenedDevelopment of vaccines
Vaccination48
  • Therefore, continuous surveillance of the benefits and adverse effects of rotavirus vaccines is required after vaccination," the investigators noted. (medscape.com)
  • Protection against rotavirus diseases seems to wane over time after vaccination. (medscape.com)
  • The specific use of the term "vaccine shedding" has risen to public prominence through anti-vaccine activists linked to misinformation related to COVID-19, who erroneously claim that COVID-19 vaccination can cause individuals to shed coronavirus spike protein and affect menstruation and fertility in women exposed to them. (wikipedia.org)
  • However, the spike protein generated by vaccination does not shed, and there is no evidence to suggest that these vaccines cause menstruation and fertility problems. (wikipedia.org)
  • Vaccination also cannot cause shedding of the COVID-19 virus since none of the COVID-19 vaccines authorized for use by the FDA or the World Health Organization as of December 2021 are live-virus vaccines. (wikipedia.org)
  • The only human vaccine to have caused any significant number of infections is the oral polio vaccine (OPV), which takes advantage of the contact immunity from shed vaccine virus to amplify the effectiveness of vaccination campaigns. (wikipedia.org)
  • A study of 345 participants aged 5-49 years who received the live influenza virus vaccine LAIV3, and for whom shedding was assessed by viral culture of nasal swabs (daily for days 1-7 post vaccination, every other day for days 9 through 25, and on day 28) indicated that 30 percent had detectable virus in nasal secretions obtained by nasal swabbing. (wikipedia.org)
  • As a result, there is "the potential to result in major reductions in vaccine coverage in developing countries, where delays in the timing of vaccination are common and exact age is not accurately recorded," the article said. (nih.gov)
  • A European study found no difference in rotavirus infection rates during the first season between infants who were breastfed and formula-fed when they received rotavirus vaccination. (nih.gov)
  • Two hundred fifty breastfed infants were randomized to receive their routine rotavirus vaccination (Rotarix) with either unrestricted breastfeeding or withholding breastfeeding from 1 hour before to 1 hour after the vaccination. (nih.gov)
  • Four hundred infants in India were randomized to either be breastfed before receiving rotavirus vaccine (Rotarix) or to not be breastfed within 30 minutes of their vaccination. (nih.gov)
  • Among 45 breastfed (at least 4 times daily) Nicaraguan infants who were given a rotavirus vaccination (Rotateq-MSD), 31 infants seroconverted and 14 infants did not. (nih.gov)
  • ABSTRACT The introduction of a rotavirus vaccine makes it important to determine the need for vaccination in a population. (who.int)
  • RÉSUMÉ En raison de l'introduction d'un vaccin antirotavirus, il est important de déterminer le besoin de vaccination dans une population. (who.int)
  • The rotavirus vaccine is part of the routine vaccination schedule recommended for children (see CDC: Child and Adolescent Immunization Schedule by Age ). (msdmanuals.com)
  • The potential for vaccination to contribute to even greater mortality reduction and accelerate attainment of the health-related Millennium Development Goals (MDG), particularly MDG4, can be realized with further improvements in vaccination coverage and large-scale introduction of new vaccines targeting an increasing number of infectious diseases. (who.int)
  • In selecting Saif for the Wolf Prize in Agriculture, the Wolf Foundation noted how "her discoveries of novel enteric and respiratory viruses of food animals and humans have led to her extensive contributions of fundamental knowledge of the gut-mammary immunologic axis and has provided new ways to design vaccines and vaccination strategies. (osu.edu)
  • The vaccination only protects against gastrointestinal infections which are triggered by rotaviruses. (vaccineinjury.info)
  • The infants suffered from congenital severe combined low immunity (SCID) which is actually a counter indication for a live vaccination. (vaccineinjury.info)
  • Live, attenuated vaccines should be administered only when an inactivated version does not exist and the risk of the disease clearly outweighs the theoretical risk of vaccination. (hivguidelines.org)
  • Use live, attenuated vaccines only if an inactivated alternative is not available and the risk of disease is greater than the risk of vaccination. (hivguidelines.org)
  • Before introduction of vaccination for rotavirus 100-150 million cases of the infections were recorded globally with 500000 of deaths. (am-online.org)
  • After introduction of rotavirus vaccination the number of infections decreased significantly and the number of deaths due to rotavirus gastroenteritis in children decreased over 50% globally. (am-online.org)
  • However, despite of confirmed safety and effectiveness of the RV1 and RV5 vaccines fear of vaccination against rotavirus infection still exists. (am-online.org)
  • 6. Fear of vaccination against rotavirus infection 7. (am-online.org)
  • The success of the polio vaccination program made it possible to replace OPV with the inactivated polio vaccine (IPV) , which contains a killed virus form. (kidshealth.org)
  • An analysis by Airfinity (health data analytics group) suggests that of the 19 million (1.9 crore) lives saved [by vaccination], the vaccine that saved most lives was the Oxford-Serum Institute one―around 6.3 million (63 lakh) lives. (theweek.in)
  • Many countries have introduced rotavirus vaccination into their national immunisation programmes, leading to a significant drop in diarrhoeal disease and hospitalisation. (edctp.org)
  • He is head of the Centre for Infectious Disease Research in Zambia, and has worked with the Ministry of Health and NGOs on projects that have significantly cut child mortality locally, including rollout of rotavirus vaccination. (edctp.org)
  • Many reports have shown that rotavirus vaccination is dangerous, particularly for children with severe combined immunodeficiency (SCID) [ 6 , 7 ]. (ophrp.org)
  • The patient's sample was tested at the Korea Disease Control and Prevention Agency to determine whether the rotavirus infection was due to vaccination or another source. (ophrp.org)
  • 41 of 46 studies in the post-vaccination period were used for meta-analysis of genotypes, 20 to calculate VE against infection, eight for VE against hospitalisation and seven for VE against severe rotavirus-diarrhoea. (biomedcentral.com)
  • Reductions in hospitalisations and mortality due to diarrhoea were observed in countries that adopted universal rotavirus vaccination. (biomedcentral.com)
  • The fourth-month vaccination recipient is now the most common recommended vaccine for children worldwide. (asapland.com)
  • This is important because under vaccination when kids go without some or even all vaccines, it has been linked to higher rates of potentially fatal diseases such as whooping cough and measles than fully vaccinated kids. (asapland.com)
  • The benefits of early vaccination for preventing vaccine-preventable diseases still outweigh the risks, they noted. (asapland.com)
  • For babies aged 8 weeks and 12 weeks, the rotavirus vaccine is routinely available on the NHS as part of the childhood vaccination programme. (pure-medical.co.uk)
  • A weakened strain of rotavirus is included in the vaccination. (pure-medical.co.uk)
  • The rotavirus vaccine has dramatically reduced the number of children who experience diarrhoea and vomiting, as well as the number of severe rotavirus infections, since its inclusion in the vaccination programme. (pure-medical.co.uk)
  • Vaccination against the stomach bug rotavirus, gives protective immunity in 98% of Finnish children, but only 46% in Bangladesh. (quadram.ac.uk)
  • Human studies have investigated the effect of how antibiotics change the microbiome and affect the immune response to influenza, polio, rotavirus, tetanus, and BCG vaccination. (quadram.ac.uk)
  • If your horses have not received any vaccination and have been leading a healthy life among other vaccinated equine friends, it is a contribution of herd immunity. (incredibleplanet.net)
  • A very common misconception is that domestic and racehorses do not need vaccines since wild horses do not undergo vaccination and they seem just as healthy. (incredibleplanet.net)
  • Dr Agoti is currently supported by the IDeAL (Initiave to Develop African Research Leaders) programme (under Mid-Career Research Fellowship) to study Viral Diarrhoea Genomics Pre- and Post-Rotavirus Vaccination in Kenya to Understand Virus Source, Transmission Patterns and Vaccine Impact. (ox.ac.uk)
  • On the other hand, if it happened that a particular vaccination was never developed for a specific disease, over time additional non-vaccine treatments and preventative measures may have been developed to tackle the disease, which haven't come to exist or, more modestly, the development of some vaccine-alternative treatments may have come about sooner. (effectivealtruism.org)
  • Further, the counterfactual of medical research funds not spent on vaccination may be a shift in budget from vaccines to other health measures. (effectivealtruism.org)
  • However, even if these types of disease were to be completely eliminated by vaccines, individuals with impaired immune systems would nonetheless remain susceptible to other types of illnesses that cannot be treated with a vaccination, and so may suffer from those illnesses instead. (effectivealtruism.org)
  • However, even though overall vaccination rates remain high, there appear to be increasing numbers of pockets of vaccine resistance where the percentage of vaccine uptake has fallen below that necessary for herd immunity, particularly in affluent coastal cities . (respectfulinsolence.com)
Infection43
  • Vaccine shedding is a form of viral shedding which can occur following a viral infection caused by an attenuated (or "live virus") vaccine. (wikipedia.org)
  • The route of infection is through contact with faeces, and some live vaccines, like the viruses they prevent, are shed in stool for up to 28 days. (wikipedia.org)
  • Other attenuated vaccines show no significant viral shedding, and inadvertent infection is rare. (wikipedia.org)
  • Research is needed to develop better treatments, including vaccines, that address both the infectious agents themselves, as well as the long-term effects of GI infection in the gut and other organ systems throughout the body. (nih.gov)
  • Globally about 30%-40% of hospitalizations and deaths due to diarrhoea among children under 5 years old, and about 5% of all child deaths, are attributed to rotavirus infection [1,6]. (who.int)
  • Rotavirus Infection Rotavirus is a common and very contagious virus that causes vomiting and diarrhea. (msdmanuals.com)
  • Rotavirus is a viral infection of the digestive tract that can cause severe dehydration. (msdmanuals.com)
  • It remains, as he and many others put it, "the perfect storm" of a viral infection resistant to a vaccine development. (nautil.us)
  • Co-circulation of both influenza A subtypes and emerging clades that spread later than the winter months may have also led to higher infection rates, perhaps due to a fitness advantage or because they evaded existing immunity. (umn.edu)
  • As a result of the analysis of the virus gene a wild type infection with rotaviruses was excluded. (vaccineinjury.info)
  • Initial trials of a similar live quadrivalent human-bovine reassortant vaccine demonstrated promising protection against rotavirus infection. (blogspot.com)
  • The quadrivalent vaccine, which was delivered to vaccinees in three oral doses at 2, 4, and 6 months of age (identical to the Merck vaccine delivery schedule), showed 74.6% efficacy against any rotavirus infection and 100% efficacy against severe rotavirus infection. (blogspot.com)
  • Important questions remain regarding how humans develop immunity to norovirus, how long immunity lasts, and whether immunity to one norovirus strain protects against infection from other strains. (cdc.gov)
  • Rotavirus (RV) infection has probably been a problem as long as humankind has existed, but the connection between RV as the leading cause of severe diarrhoeal disease and dehydration in children under the age of five worldwide was only made in the 1970s [ 1 ]. (biomedcentral.com)
  • The neutralizing epitope of VP8* was produced in tobacco plants and has shown to confer protection against bovine rotavirus infection in a mouse model [ 9 ]. (biomedcentral.com)
  • 2. Pathogenesis of rotavirus infection. (am-online.org)
  • 4. Epidemiology of rotavirus infection. (am-online.org)
  • These results indicated that eukaryotic bicistronic plasmid DNA vaccines could be successfully constructed to enhance humoural, mucosal and cellular immune response against rotavirus infection. (ojvr.org)
  • A professor of paediatric infection and immunity at the University of Oxford, Pollard is currently working on a vaccine to prevent paratyphoid, an infection that is common among children in India. (theweek.in)
  • The rotavirus vaccine is a live vaccine, and there is a possibility of infection by the virus strain used in the vaccine. (ophrp.org)
  • We investigated the process of determining whether an infection was caused by the vaccine strain in a severe complex immunodeficiency (SCID) patient with rotavirus infection. (ophrp.org)
  • The testing process was conducted in the following order: confirming rotavirus infection, determining its genotype, and confirming the vaccine strain. (ophrp.org)
  • Rotavirus infection was confirmed through enzyme immunoassay and VP6 gene detection. (ophrp.org)
  • Genotypes G1 and P[8] were identified, and the infection was suspected of having been caused by rotavirus G1P[8]. (ophrp.org)
  • Therefore, the infection was confirmed to have been caused by the vaccine strain by analyzing the genetic relationship between VP4 and VP7. (ophrp.org)
  • Rotavirus infection by the vaccine strain can be identified through genotyping and fingerprint gene detection. (ophrp.org)
  • Therefore, it is necessary to consider the pathogen characterization process for investigating vaccine-related infection cases. (ophrp.org)
  • This study reviewed the process of examining a specimen from a SCID patient with confirmed rotavirus infection. (ophrp.org)
  • Subsequently, he had persistent diarrhea and was diagnosed with rotavirus infection through a rotavirus test. (ophrp.org)
  • An antigen test (enzyme immunoassay, EIA) and a genetic test (VP6) were performed on the supernatant fluid after centrifugation to re-confirm the rotavirus infection. (ophrp.org)
  • The correct answer is A. People 50 years of age and older are recommended to receive a shingles vaccine because the virus that causes chickenpox remains in the nerves after the initial infection subsides. (chop.edu)
  • When Could You Claim Compensation For A Rotavirus Infection? (legalexpert.co.uk)
  • But what if they suffer from rotavirus infection because of someone else's negligence? (legalexpert.co.uk)
  • What Is A Rotavirus Infection? (legalexpert.co.uk)
  • However, the symptoms are similar, as a rotavirus infection can cause vomiting, diarrhoea and nausea. (legalexpert.co.uk)
  • In most cases, a rotavirus infection doesn't prove to be particularly serious, though it's still distressing to suffer from. (legalexpert.co.uk)
  • Hospitalizations in Ontario due to rotavirus infection were reduced by 71 percent and emergency department visits dropped by 68 percent," according to Dr. Sarah Wilson , lead author of the study and a medical epidemiologist at Public Health Ontario and an adjunct professor at the Institute for Clinical Evaluative Sciences (ICES). (acsh.org)
  • The four major causes of Diarrhea in the kids during the first month of life are Colibacillosis, rotavirus infection, salmonellosis, and cryptosporidiosis. (farmingx.in)
  • Apart from antibiotic resistance, there is little or no time to figure out acute forms of colibacillosis as well as rotavirus infection and to take steps to save the kids. (farmingx.in)
  • As part of their standard childhood vaccines, newborns are given an oral vaccine against rotavirus infection. (pure-medical.co.uk)
  • The rotavirus vaccine is quite successful at protecting children from rotavirus infection. (pure-medical.co.uk)
  • After getting vaccinated, a newborn can have rotavirus infection, although this is uncommon, and the disease is usually milder than it would be if they hadn't been vaccinated. (pure-medical.co.uk)
  • Passive immunity provides immediate protection against infection, but that protection is temporary. (cdc.gov)
Rotarix12
  • Among six types of vaccines currently in use, two live-attenuated oral vaccines: the two-dose monovalent Rotarix (RV1) and three-dose pentavalent RotaTeq (RV5]) are in use worldwide. (medscape.com)
  • ROTARIX is a vaccine indicated for the prevention of rotavirus gastroenteritis caused by G1 and non-G1 types (G3, G4, and G9). (nih.gov)
  • The vaccines, RotaTeq and Rotarix, have not been shown to be involved with the potentially fatal intestinal condition in infants that led to the first vaccine, RotaShield, being removed from the market in 1999. (nih.gov)
  • A subset of 300 infants in a multicenter European rotavirus efficacy trial had antirotavirus IgA titers measured 1 to 2 months after the second rotavirus dose (Rotarix - GSK). (nih.gov)
  • Rotarix contains an attenuated human rotavirus strain which stemmed from a child in the USA . (vaccineinjury.info)
  • Composition of Rotarix (Glaxo-Smith-Kline): After reconstitution 1 dosage (1 ml) contains: Human rotavirus, RIX4414-strain, live attenuated minimum 106.0 ZKID50. (vaccineinjury.info)
  • Rotarix (RV1) and the pentavalent vaccine Rotateq (RV5). (am-online.org)
  • The vaccines that are licensed and used in Korea are Rotarix (GlaxoSmithKline Biologicals, Rixensart, Belgium) and RotaTeq (Merck Sharp & Dohme Corp., Kenilworth, NJ, USA). (ophrp.org)
  • Rotarix is a vaccine used to protect children from rotaviruses, viral infections that affect the digestive tract and lead to severe diarrhea in babies and young children. (newsomelaw.com)
  • The U.S. Food and Drug Administration has asked doctors to stop using the Rotarix vaccine while investigations are conducted. (newsomelaw.com)
  • Until further studies done, doctors will not be permitted to use the Rotarix vaccine. (newsomelaw.com)
  • Rotarix is a liquid suspension of the live, thin strain of human rotavirus made by GlaxoSmithKline. (newsomelaw.com)
Infants18
  • An increasing number of observations, obtained from analyses of (i) natural rotavirus infections in infants and young children, (ii) experimental rotavirus infections in laboratory animals, and (iii) extensive rotavirus vaccine field trials performed in different populations of various parts of the world, appears to support the concept that serotype-specific antibodies to rotaviruses play an important role in protection against rotavirus-associated illnesses. (nih.gov)
  • Rotavirus vaccines are used only in infants and are not indicated for use in women of childbearing age. (nih.gov)
  • Breastfeeding protects infants against acute gastroenteritis caused by rotavirus. (nih.gov)
  • The seroconversion failures were mostly in infants who had high preimmunization IgA levels and whose mothers had high serum IgG antibody levels against rotavirus. (nih.gov)
  • Ten researchers from the CDC's National Centers for Immunization and Respiratory Disease (NCIRD) released a paper arguing that because the immune-boosting effects of breastmilk inhibit the effects of the live oral rotavirus vaccine, nursing mothers should delay breastfeeding their infants. (foodrenegade.com)
  • Yet instead of recommending that the best way to fight this disease in infants is to encourage mothers to breastfeed, they're recommending that mothers refrain from breastfeeding so that the vaccine can work! (foodrenegade.com)
  • Group A rotaviruses are a major cause of severe diarrhea in infants. (cdc.gov)
  • Patients with HIV should avoid handling diapers of infants vaccinated against rotavirus in the previous 4 weeks, and all household members should wash their hands after changing diapers of an infant recently vaccinated against rotavirus. (hivguidelines.org)
  • Association of maternal immunity with rotavirus vaccine immunogenicity in Zambian infants. (edctp.org)
  • Immunogenicity of rotavirus vaccine (RotarixTM) in infants with environmental enteric dysfunction. (edctp.org)
  • Dr Roma Chilengi is exploring whether an additional dose of rotavirus vaccine provides infants with additional protection against this important gastrointestinal pathogen. (edctp.org)
  • Rotavirus is a common cause of severe enteritis in newborns and infants worldwide. (ophrp.org)
  • Today, infants receive four doses of DTaP (diphtheria, tetanus, acellular pertussis) vaccine before 2 years of age as part of the recommended infant immunization schedule. (chop.edu)
  • More information on vaccine considerations for newborns and infants is available on the VEC's birth to 2-years-old page or on the Newborns and Infants Pinterest board . (chop.edu)
  • This is part of routine immunization programs for all infants aged 2-3 months as DPT-HepB-Hib Vaccine (Triple Combination) in India. (asapland.com)
  • There is a lot of variety in how infants respond to vaccines across countries. (quadram.ac.uk)
  • Both bacteria appear to affect how well infants respond to vaccines. (quadram.ac.uk)
  • Another important aspect of the effectiveness of vaccines is how the vaccine is delivered to infants. (quadram.ac.uk)
RotaTeq3
  • A vaccine for rotavirus (Rotateq) developed by Merck, the Children's Hospital of Philadelphia and Paul Offit, America's most quoted promoter and apologist for the vaccine industry, will be considered for licensure on December 14 and by the Vaccines and Related Biological Products Advisory Committee of the Center for Biologics Evaluation and Research of the FDA. (blogspot.com)
  • [3] Differing from the Merck vaccine only by the exclusion of serotype G4, this vaccine's results likely mirror the protection that RotaTeq® will afford. (blogspot.com)
  • By detecting the fingerprint gene (WC3) of RotaTeq, it was confirmed that the detected virus was the vaccine strain. (ophrp.org)
Develop immunity5
  • They are prepared by introducing Genes encoding the production of vaccine particles into yeast, certain bacteria or tissue cultures, which then themselves produce the particles needed to develop immunity. (wikilectures.eu)
  • Say's Dr Louis Hampers , these biological preparations help our bodies develop immunity against diseases like measles, chicken pox and polio. (louishampersmd.com)
  • This helps your baby develop immunity so that they won't catch rotavirus the next time they come into touch with it. (pure-medical.co.uk)
  • This vaccine works by exposing the child to a tiny dose of the virus, enabling the body to develop immunity to the rotavirus disease. (newsomelaw.com)
  • This will help piglets develop immunity after they've ingested colostrum. (amstewardship.ca)
Strains9
  • However, under conditions of persistent circulation in undervaccinated populations, reversion mutations that reactivate the virus can give rise to disease-causing circulating vaccine-derived poliovirus (cVDPV) strains, and this vaccine is no longer used in developed countries. (wikipedia.org)
  • Another factor could be that the 2018 flu vaccine provided suboptimal protection against the strains. (umn.edu)
  • Epidemiologic studies of rotavirus infections are increasingly showing that a great diversity of rotavirus strains are cocirculating in the human population throughout the world. (cdc.gov)
  • our primary goals were to determine the prevalence of rotavirus diarrhea in hospitalized children, the G and P types among infecting rotavirus strains, and the temporal and geographic differences in strain distribution throughout the regions. (cdc.gov)
  • In 2007 two oral rotavirus vaccines containing live attenuated strains were registered in Europe: the monovalent vaccine. (am-online.org)
  • G1P[8] is the most commonly detected genotype worldwide and is not included in the recombinant strains used in vaccines. (ophrp.org)
  • However, genetic linkage analysis will also help to identify vaccine strains. (ophrp.org)
  • We describe the effectiveness of rotavirus vaccines to prevent rotavirus infections and hospitalizations and the main rotavirus strains circulating before and after vaccine introduction through a systematic review and meta-analysis of studies published between 1990 and 2014. (biomedcentral.com)
  • Genomics and epidemiology help us improve diagnostics, and find out whether some additional strains need to be included in future vaccines. (ox.ac.uk)
Vaccinations7
  • I have had allergic reactions in the past to vaccinations - can I still get the COVID-19 vaccine? (wfyi.org)
  • That being said, the Pfizer-BioNTech and Moderna vaccines require two doses to be effective - more similar to many childhood vaccinations than getting a flu shot. (wfyi.org)
  • They looked at rotavirus vaccinations and diarrhea cases reported in children in the main hospital in Blantyre, Malawi. (umn.edu)
  • The findings, published in Frontiers in Public Health, suggest that delaying certain vaccinations and spacing them out over a more extended period might reduce vaccine-related health complications. (asapland.com)
  • Given this trend, researchers hypothesize that "parents are placing their children at an increased risk for vaccine-preventable diseases" and that "delaying or spacing out infant vaccinations could be increasing the risk that children will contract these illnesses. (asapland.com)
  • To be fully protected, your kid will require two rotavirus vaccinations spaced at least four weeks apart. (pure-medical.co.uk)
  • estimates that for children vaccinated between 2001 and 2020 in 73 GAVI-supported countries, 34 million deaths will be prevented over the course of their lifetimes, and 1,600 million DALYs will be saved, as a direct result of vaccinations (this excludes the impact of the routinely given diphtheria, pertussis, BCG, and first-dose measles vaccines). (effectivealtruism.org)
Immunization7
Infections10
  • However, the OPV is still used in Asia and Africa, leading to a small number of vaccine-induced polio infections each year. (wikipedia.org)
  • There is growing concern that geohelminth infections, particularly exposures occurring during early life in utero through maternal infections or during infancy, may affect vaccine immunogenicity in populations among whom these infections are endemic. (biomedcentral.com)
  • The regulation of host immunity by chronic geohelminth infections may not just affect responses to parasite antigens but also other exogenous antigens such as the antigenic constituents of vaccines and aeroallergens. (biomedcentral.com)
  • Other diarrhea infections (which are caused by other pathogens than rotaviruses) can continue to appear in vaccinated children. (vaccineinjury.info)
  • Rotavirus infections are a leading cause of severe gastroenteritis in children under five years of age. (am-online.org)
  • A In highly vaccinated populations, and countries where there have been multiple waves of infections, we see a high level of immunity. (theweek.in)
  • Despite intensive vaccine development, vaccines against infections caused by antigenically more complex agents, such as parasites , yeast and mycoplasmas . (wikilectures.eu)
  • You should provide immunity against several infections at the same time. (wikilectures.eu)
  • 203 studies were included to estimate the proportion of infections due to rotavirus and 10 to assess the impact of the vaccines. (biomedcentral.com)
  • Co-infections might influence vaccine immunity. (ox.ac.uk)
Viral15
  • Abstract: The purpose of this supplement request is to support a complementary and newly developed improved approach to the ongoing studies in our original R01 AI099451 (Title: Gut microflora: Impact on neonatal immunity, viral gastroenteritis and vaccines) by testing a novel probiotic delivery system to prolong the persistence of probiotics in the gut and to enhance their beneficial effects. (nih.gov)
  • It is highly relevant to the goals of the RFA including discovery of dietary supplements to reduce the risk for chronic conditions and as an administrative supplement to enhance our research on probiotics to prevent viral diarrheas and stimulate neonatal immunity. (nih.gov)
  • Most vaccines are not attenuated (live virus) vaccines, and therefore cannot cause vaccine-induced viral shedding. (wikipedia.org)
  • It is impossible with other vaccine technologies such as inactivated vaccine (killed-virus vaccines), viral vector vaccine, RNA vaccines (that contain no virus), or subunit vaccines (a vaccine technology using only isolated proteins of a virus). (wikipedia.org)
  • With the exception of the oral polio vaccine (OPV), there have been no documented cases of vaccine-induced viral shedding that has infected contacts of a person vaccinated with an attenuated (live-virus) vaccine. (wikipedia.org)
  • In dogs, vaccine-induced viral shedding has been observed with live attenuated Canine parvovirus vaccines. (wikipedia.org)
  • In anticipation of vaccine development and use, CDC recently began national surveillance for the viral agents of gastroenteritis. (cdc.gov)
  • Health-care facilities involved in the detection of rotavirus or the other viral agents of diarrhea can participate. (cdc.gov)
  • Could you talk about how knowledge of the viral genome have helped in development of vaccines over the last two decades? (nih.gov)
  • The major protein in the central layer of the viral capsid is VP6, which determines 7 different groups of rotaviruses (A-G). The outer layer of the viral capsid is composed of 2 structural proteins, VP4 (encoded by gene 4) and VP7 (encoded by gene 7, 8, or 9, depending on the strain) ( 3 ). (cdc.gov)
  • 1997). It was previously reported that parenteral immunisation with rotavirus VP4, VP6 and VP7 DNA vaccines induce high levels of serum rotavirus Immunoglobulin G (IgG) but fail to protect mice against viral challenge (Chen et al . (ojvr.org)
  • The rotavirus nonstructural protein 4 (NSP4) is the first described viral enterotoxin and may inducing dose- and age-dependent diarrhoea in neonatal mice without causing histological alterations (Ball et al . (ojvr.org)
  • VP7 is a structural protein of the outer capsid of a rotavirus and is encoded in the seventh, eighth or ninth gene segment of the genome (depending on the viral strain) (Song & Hao 2009). (ojvr.org)
  • Dr. Permar's work focuses on the development of vaccines to prevent vertical transmission of neonatal viral pathogens. (duke.edu)
  • Out of them, colibacillosis (E Coli scours) is the most common bacterial diarrhea while in the viral agent's Rotavirus is the most common. (farmingx.in)
Herd9
Antibodies12
  • Declining vaccine-induced antibodies, RVGE-acquired protection from the vaccine's indirect effects, or exposure to unvaccinated populations may explain gradual loss of immunity. (medscape.com)
  • Neutralizing antibodies, the backbone of many vaccines, do not stop it, and most importantly, HIV begins its assault on the body by attacking CD4 T cells, which serve as the command center of much of the immune system. (nautil.us)
  • 1996). When mice were infected with rotavirus, NSP4-speci﫿c Immunoglobulin A (IgA) antibodies were generated in response to mucosal immunisation and transcytosed from the basal lamina into the mucosal epithelium (Gebert 1997). (ojvr.org)
  • Further, orally immunised mice produced maternal antibodies against NSP4, generating passive protection in newborn mouse pups against rotavirus challenge (Ward, Rich & Besser 1996). (ojvr.org)
  • VP7 may be the dominant immunogen for the production of neutralising antibodies, which are thought to have an important role in the protection against rotavirus-induced diarrhoea (Ward et al . (ojvr.org)
  • 1989) demonstrated that VP7 monoclonal antibodies (MAbs) have two distinct epitopes, with the specific epitopes defined by VP7-specific MAb 57-8 mediating protection against at least two rotavirus serotypes. (ojvr.org)
  • No, the immune system makes antibodies against a germ, like the chickenpox virus, whether it encounters it naturally or through a vaccine. (kidshealth.org)
  • Are monoclonal antibodies a potential vaccine substitute for them? (theweek.in)
  • Seroconversion = induces the synthesis of detectable antibodies after administration of the vaccine. (wikilectures.eu)
  • Just like in humans, vaccines strengthen the equine immune system and prepare the antibodies to fight against common but serious diseases. (incredibleplanet.net)
  • To achieve passive transfer of immunity from the sow, piglets must consume colostrum that is of good quality - that is, high levels of immunoglobulins or antibodies ( IgG, IgA, IgM ), immune cells, and other antimicrobial substances - quickly after birth. (amstewardship.ca)
  • Some vaccines are available, specifically for E. coli , rotavirus, and Clostridial disease that can be administered to sows and gilts prior to farrowing to generate more specific antibodies against these pathogens and deposit them in their colostrum. (amstewardship.ca)
Diseases19
  • The data will inform an ongoing debate of potential effects of geohelminths on child health and will contribute to policy decisions on new interventions designed to improve vaccine immunogenicity and protect against the development of allergic diseases. (biomedcentral.com)
  • In the era before vaccines, many children in the U.S. died or became disabled from these diseases. (nih.gov)
  • Diarrhoea diseases are the second most frequent cause of death among young children in the Eastern Mediterranean Region [1,2] and rotavirus disease is the single most important cause of severe gastroenteritis in children throughout the world [3-5]. (who.int)
  • Immunity (the ability of the body to defend itself against diseases caused by. (msdmanuals.com)
  • Vaccines have protected millions of kids from dangerous diseases and saved thousands of lives. (kidshealth.org)
  • In fact, some diseases are so rare now that parents sometimes ask if vaccines for them are even needed. (kidshealth.org)
  • But most diseases that can be prevented by vaccines do still exist in the world, even in the United States, although they happen very rarely. (kidshealth.org)
  • But the risk of serious reactions is small compared with the health risks from the often-serious diseases they prevent, and do not happen because the baby got several vaccines at once. (kidshealth.org)
  • When it comes down to it, there's no better way to protect yourself and your family than by getting vaccinated against vaccine-preventable diseases like measles, mumps and chickenpox (to name just a few). (louishampersmd.com)
  • As July rolls into August, it is a good time to make sure your child is up to date on vaccines against polio and other diseases, so that when back-to-school time arrives, you aren't struggling to get an appointment with a busy healthcare provider. (chop.edu)
  • President James Garfield experienced the loss of two of his children from vaccine-preventable diseases. (chop.edu)
  • While the diseases Washington suffered aren't as great a worry for many of today's teens , there are vaccines that teens should get, including those against HPV, meningococcus, tetanus, diphtheria and pertussis. (chop.edu)
  • The prevalence of use of different formulations varies by country due to factors including trust in vaccines, access to vaccines through the public health system or private provider payment systems, availability of funding for immunizations through national budgets or donor support for specific diseases, perceptions about disease severity and the need for a vaccine. (asapland.com)
  • Some vaccine-preventable diseases like flu and whooping cough remain common in the United States. (vaccinateyourfamily.org)
  • Luckily, we have the ability to protect ourselves from 16 serious diseases during our childhood and teen years, and several additional vaccines to protect ourselves as adults. (vaccinateyourfamily.org)
  • Learn more about these vaccine-preventable diseases and the vaccines that protect against them below. (vaccinateyourfamily.org)
  • People in the U.S. still get sick, become disabled and even die because of vaccine-preventable diseases. (vaccinateyourfamily.org)
  • Please watch and read stories from families that were impacted, sometimes tragically, by vaccine-preventable diseases. (vaccinateyourfamily.org)
  • It is our hope that the information and resources on this page - and throughout this website - will help answer any questions you have about vaccine preventable diseases and the vaccines that help prevent those diseases. (vaccinateyourfamily.org)
Immunogenicity6
  • Their systematic review and meta-analysis of randomized clinical trials, case-control, and cohort studies compared benefit, risk, and immunogenicity of these vaccines and their effectiveness in reducing RVGE. (medscape.com)
  • All of the studies reported on the safety and effectiveness or immunogenicity of rotavirus vaccines. (medscape.com)
  • They also found a positive correlation between immunogenicity and vaccine protection. (medscape.com)
  • The immunogenicity of the quadrivalent vaccine was reflected in an increased ratio of rotavirus specific IgA to total IgA as measured in the vaccinee's stool. (blogspot.com)
  • Immunogenicity, vaccine response monitoring, and requirements for additional booster doses for patients with HIV are discussed on pages for individual vaccines. (hivguidelines.org)
  • 2001). It is therefore necessary to develop an efficient method to increase the immunogenicity of DNA vaccines. (ojvr.org)
Polio vaccine3
  • One live virus vaccine that's no longer used in the United States is the oral polio vaccine (OPV). (kidshealth.org)
  • They analyzed data from more than 1,200 kids between 19 and 35 months old who had received four doses of DtaP (diphtheria, tetanus, pertussis), one dose of the polio vaccine, and one shot against pneumococcus bacteria. (asapland.com)
  • Early and important player in the race to find a polio vaccine. (one.org)
Prevent rotavirus1
  • The drug helps prevent rotavirus gastro-enteritis in children, which affects their digestive system. (newsomelaw.com)
Pentavalent vaccine2
  • There are two live rotavirus vaccines currently available, one based on human rotavirus serotype G1P[8], and the other a G1-G4 P[8] pentavalent vaccine. (biomedcentral.com)
  • Many countries have adopted the pentavalent vaccine (DPT+Hep B+Hib), which is given in five shots over six months, starting at two months of age. (asapland.com)
Doses12
  • Health care workers received the first doses of a COVID-19 vaccine on Monday, Dec. 14. (wfyi.org)
  • States began receiving the first doses of COVID-19 vaccines this week, and more doses will follow. (wfyi.org)
  • The COVID-19 vaccine doses developed by Pfizer-BioNTech and Moderna use a new type of vaccine, an mRNA vaccine. (wfyi.org)
  • The developments triggered distribution of a record 12.5 million vaccine doses, which would cover about half of the country's population. (umn.edu)
  • Some vaccines use small doses of the viruses they prevent and are similar to the disease they fight. (providafamilymedicine.com)
  • Killed vaccines use dead forms of the virus and have less long-lasting protection, so multiple doses may be necessary. (providafamilymedicine.com)
  • The series has two or three doses, depending on which vaccine is chosen. (asapland.com)
  • Now, there is a vaccine in the form of two doses for the child to receive. (legalexpert.co.uk)
  • Additionally, there's the possibility of the child still contracting a serious case of rotavirus despite their two doses. (legalexpert.co.uk)
  • Although the exact duration of protection is unknown, studies have shown that two doses of the vaccine can protect a child for several years. (pure-medical.co.uk)
  • This vaccine is given in two oral doses to children who are between the ages of 6 weeks and 32 weeks old. (newsomelaw.com)
  • This week, international health officials posted an alert urging travelers everywhere to get the recommended two doses of vaccine before flying overseas. (respectfulinsolence.com)
Strain12
  • The vaccine strain is a serogroup A, G1P[8] virus. (vaccineinjury.info)
  • The vaccine, which was approved in the US in the spring of 2006 and in June 2006 in Germany contains live, weakened rotavirus which is human-bovine in origin (WC3-strain). (vaccineinjury.info)
  • Paul Offit at The Children's Hospital of Philadelphia developed a vaccine based on a bovine strain of rotavirus (WC-3). (blogspot.com)
  • Aiming to avoid the adverse affects that RotaShield® was associated with, the vaccine is based on a bovine strain of rotavirus. (blogspot.com)
  • The bovine strain was chosen because it replicates less prolifically in the human gastrointestinal tract than the simian strain used for the tetravalent rhesus reassortant vaccine. (blogspot.com)
  • We report an effort to develop an affordable candidate rotavirus vaccine against the new emerging G9P[6] (RVA/Human-wt/ZAF/GR10924/1999/G9P[6]) strain. (biomedcentral.com)
  • Our results suggest that the rotavirus proteins produced in N. benthamiana are candidates for a subunit vaccine specifically for the G9P[6] rotavirus strain. (biomedcentral.com)
  • The attenuated Salmonella typhimurium χ4550 strain was used to harbour a reconstructed bicistronic DNA vaccine against porcine rotavirus, which carried the rotavirus nonstructural protein 4 ( NSP4 ) and VP7 genes simultaneously. (ojvr.org)
  • The NSP4 cleavage product (259-525) of rotavirus OSU strain and VP7 full-length genes were amplified by reverse transcription polymerase chain reaction and then inserted into the eukaryotic single-expression plasmid, pVAX1-asd, and the eukaryotic dual-expression plasmid, pVAXD-asd, respectively. (ojvr.org)
  • In addition, we reviewed the laboratory analysis process to determine whether the vaccine-derived strain of rotavirus has infected a SCID patient. (ophrp.org)
  • We hope that if we find a particular strain or product of the beneficial bacteria involved in the immune response, we could give it to those babies that lack it and boost their response to vaccines. (quadram.ac.uk)
  • Dr Anna's isolation of a strain of diphtheria in 1894 was used to develop the first diphtheria antitoxin and later a diphtheria vaccine. (one.org)
Third dose of rotavirus3
  • Their findings suggested that a third dose of rotavirus vaccine at 9 months would provide only a 5% to 16% reduction in overall rotavirus-associated gastroenteritis over the first 3 years. (umn.edu)
  • In his EDCTP Senior Fellowship, Dr Chilengi is assessing whether adding a third dose of rotavirus vaccine at nine months boosts rotavirus-specific immune responses at 1 year, providing longer-lasting protection. (edctp.org)
  • Dr Chilengi's Senior Fellowship project will determine whether a third dose of rotavirus vaccine compensates for the reduced effectiveness of such vaccines in LMICs - information that will be highly relevant not just to Zambia but also to other LMICs. (edctp.org)
Influenza2
  • Influenza type b vaccines have been introduced in 45 and 43 countries respectively. (who.int)
  • For patients with HIV and CD4 counts ≥200 cells/mm 3 , inactivated forms of vaccines such as those for polio, influenza, typhoid, and zoster are preferred over the live vaccine options. (hivguidelines.org)
Tetanus3
  • Primary study outcomes are the development of protective immunity to common childhood vaccines (i.e. rotavirus, Haemophilus influenzae type B, Hepatitis B, tetanus toxoid, and oral poliovirus type 3) during the first 5 years of life, the development of eczema by 3 years of age, the development of allergen skin test reactivity at 5 years of age, and the development of asthma at 5 and 8 years of age. (biomedcentral.com)
  • Diphtheria is now completely preventable, and children around the world are protected from it through the combined diphtheria, tetanus and pertussis (DTP) vaccines. (one.org)
  • They then combined it with two other vaccines (diphtheria and tetanus) into a single shot - known today as the DTP vaccine. (one.org)
Measles3
  • 3. Table 1: 2008-2009 DPT3 and measles-containing vaccine-1 (MCV1) reported administrative coverage. (who.int)
  • Only those vaccines made from weakened (also called attenuated ) live viruses - like the chickenpox (varicella) and measles-mumps-rubella (MMR) vaccines - could possibly make a child develop a mild form of the disease. (kidshealth.org)
  • When that happens, if measles finds its way into a community with low vaccine uptake rates, the chance of an outbreak, even a major outbreak, rises. (respectfulinsolence.com)
Diarrhea6
Varicella2
Pertussis1
  • The correct answer is C. Pregnant women are recommended to get Tdap vaccine to protect their unborn babies from pertussis in the weeks and months after birth before they are immunized. (chop.edu)
Diarrhoea14
  • Human rotaviruses, the major aetiological agents of severe infantile diarrhoea worldwide, display surprisingly diverse and complex serotypic specificities. (nih.gov)
  • This study in Jordan in 2007-08 determined the incidence and clinical features of rotavirus gastroenteritis among children aged under 5 years admitted to hospital with diarrhoea. (who.int)
  • 2001) and 2/6-VLP vaccines do not protect suckling mouse pups from rotavirus diarrhoea (Coste et al . (ojvr.org)
  • 1990, 1993) and associate resistance to protect the host against diarrhoea upon challenge with the virulent parental rotaviruses (Hoshino et al . (ojvr.org)
  • Globally, diarrhoea is the second biggest killer of children, and rotavirus is the leading cause of severe diarrhoea in children under 5 years of age. (edctp.org)
  • Rotavirus was the leading cause of childhood diarrhoea-related hospitalisations and death before the introduction of rotavirus vaccines. (biomedcentral.com)
  • 24.3 % (95 % CI 22.1-26.5) and 16.1 % (95 % CI 13.2-19.3) of cases of diarrhoea were due to rotavirus before and after vaccine introduction, respectively. (biomedcentral.com)
  • Rotavirus vaccines are effective in preventing rotavirus-diarrhoea in children in Latin America. (biomedcentral.com)
  • Diarrhoea is the second most important cause of childhood death worldwide and rotavirus is the pathogen most frequently associated with severe diarrhoea [ 1 ]. (biomedcentral.com)
  • This large scale regional experience has resulted in reports of vaccine effectiveness (VE) to prevent severe diarrhoea and hospitalisations. (biomedcentral.com)
  • Rotavirus is a highly contagious stomach disease that primarily affects newborns and young children, producing diarrhoea, vomiting, tummy soreness, and a fever. (pure-medical.co.uk)
  • As with any vaccine, some babies may experience side effects such as diarrhoea, although these are usually minor and do not persist long. (pure-medical.co.uk)
  • Vaccines against rotavirus, the most common cause of diarrhoea globally, don't work well in LMICs populations that need them the most. (ox.ac.uk)
  • In 1973, Bishop led a team that discovered rotavirus, a major cause of severe diarrhoea in children. (one.org)
Dose of the vaccine2
  • People who have had serious allergic reactions to a previous dose of the vaccine or to a vaccine component should not be given the rotavirus vaccine. (msdmanuals.com)
  • Why do we have to get a second dose of the vaccine? (wfyi.org)
Chickenpox3
Effectiveness4
  • Analyzing newer, less widely distributed vaccines, Rotavac, Rotasiil, and Lanzhou lamb rotavirus vaccine also showed moderate effectiveness in reducing RVGE risk. (medscape.com)
  • Two new vaccines against rotavirus are working well without dangerous side effects in the United States, but guidelines for their use may impair full effectiveness in developing countries, according to a New England Journal of Medicine article co-authored by Fogarty Director Dr. Roger I. Glass . (nih.gov)
  • They also conducted computer modeling simulations to gauge strategies for improving vaccine effectiveness. (umn.edu)
  • A preliminary assessment of rotavirus vaccine effectiveness in Zambia. (edctp.org)
Illness10
  • Research supported by NIH and others proves that the benefits of vaccines in preventing illness and death greatly outweigh the risks. (nih.gov)
  • If people have a temporary illness, doctors usually wait to give the vaccine until the illness resolves. (msdmanuals.com)
  • There are also relevant questions as to how a norovirus vaccine would be used to prevent the most disease and protect those at highest risk for severe illness. (cdc.gov)
  • Vaccines work by preparing the body to fight illness. (kidshealth.org)
  • Vaccines keep millions of people healthy each year by preparing the body to fight illness. (kidshealth.org)
  • Vaccines are not the only way to fight illness. (louishampersmd.com)
  • But vaccines aren't just about preventing illness-they also provide protection against lifelong disabilities like autism and other neurological disorders. (louishampersmd.com)
  • What's particularly interesting is we saw a drop even in older kids who were too old to receive the publicly-funded rotavirus vaccine, which means that protecting babies against illness also benefitted older children. (acsh.org)
  • The transition between maternal immunity to a piglet's own immunity leaves them susceptible to illness and disease for a short period of time. (amstewardship.ca)
  • I believe the truth is that the doctors and researchers are completely fascinated with what science can do, with the possibility that different types of chemicals can change how our bodies react to environmental stimuli (vaccines prevent illness, antibiotics kill it, hormones prevent pregnancy, etc. (modernalternativemama.com)
Types of vaccines1
Skip1
  • If you were as disturbed as I was about some of the vaccines on the schedule, you may have decided to skip certain ones, or at least want to wait until your baby is older before offering some or all of them. (modernalternativemama.com)
Mucosal1
  • 9 International Research and Development Center for Mucosal Vaccine, The Institute of Medical Science, University of Tokyo, Tokyo, Japan. (jci.org)
Viruses5
  • Serious illnesses have not been reported among unvaccinated persons infected inadvertently with vaccine viruses. (wikipedia.org)
  • Flu and rabies shots use an inactive version of the virus, but that's why you don't develop long-term immunity from those viruses. (wfyi.org)
  • Rotaviruses are non-enveloped viruses in the family Reoviridae, genus Rotavirus . (biomedcentral.com)
  • It's impossible to get the disease from any vaccine made with dead (killed) bacteria or viruses or just part of the bacteria or virus. (kidshealth.org)
  • They were the first to prove that an inactive or "killed" virus could produce immunity in monkeys, overturning the previous belief that only live viruses could create polio immunity. (one.org)
Anti-vaccine9
  • Yet still somehow there exist fruit loops among us who have been able to confound the masses with agenda driven, anti-vaccine rhetoric. (acsh.org)
  • Featuring prominently in this quackfest will be an anti-vaccine rally in Grant Park on Wednesday featuring some really bad, anti-vaccine fundamentalist Poe-worthy "music" and a keynote speech by Andrew Wakefield himself . (scienceblogs.com)
  • If you want evidence that Andrew Wakefield is being disingenuous at best and lying through his teeth at worst when he claims he's not "anti-vaccine," look no further than his having agreed to give the keynote speech at this rally. (scienceblogs.com)
  • One can only hope that the anti-vaccine movement posts YouTube videos of his speech so that I can apply a needed dose of not-so-Respectful Insolence to it. (scienceblogs.com)
  • Add to Autism One and the anti-vaccine loon rally the fact that Andrew Wakefield is releasing his book on the whole GMC affair, a book entitled, appropriately enough Callous Disregard: Autism and Vaccines--The Truth Behind a Tragedy . (scienceblogs.com)
  • More importantly, the confluence of Autism One, its associated anti-vaccine rally, and Wakefield's interview with Matt Lauer allows the anti-vaccine lunatic fringe to try to distract attention from what is really important about this week, and that is the fact that almost certainly shortly after this post goes live Andrew Wakefield will lose his license to practice medicine in the U.K. (scienceblogs.com)
  • One thing that Deer's introduction reminds me of, though, is that, whatever the problems with the GMC hearings on Andrew Wakefield and his cronies, being a " kangaroo court " or a " witch hunt " is not among them, although that is certainly the spin that the anti-vaccine movement is trying to put on them. (scienceblogs.com)
  • That's why the common anti-vaccine refrain that says that you shouldn't worry about unvaccinated children being a threat to your children if you've vaccinated them is nonsense. (respectfulinsolence.com)
  • The anti-vaccine movement, at least the Wakefieldian wing that says that the MMR vaccine causes autism, is definitely stronger in the U.K. than it is here and arguably also stronger in Europe than it it is here. (respectfulinsolence.com)
DTaP2
  • This is the type of vaccine is used for the DTaP vaccine. (providafamilymedicine.com)
  • For example, the US recommends a 5-dose DTaP schedule and a 3-dose Hib vaccine series. (asapland.com)
Serotypes1
  • However, the recent emergence of the G9 and other novel rotavirus serotypes in Africa and Asia has prompted fears that current vaccines might not be fully effective against these new varieties. (biomedcentral.com)
Childhood2
  • Because the most widely used vaccines are administered during the first year of life and the antecedents of allergic disease are considered to occur in early childhood, the present study has been designed to investigate the impact of early exposures to geohelminths on the development of protective immunity to vaccines, allergic sensitization, and allergic disease. (biomedcentral.com)
  • The returning traveler infected American children who hadn't been vaccinated because of safety concerns-despite study after study showing that childhood vaccines are safe and effective. (nih.gov)
Cause of severe1
Bacteria2
  • Conjugate vaccines use bacteria in combination with proteins to provides protection from the harmful parts of the germ. (providafamilymedicine.com)
  • Exactly how beneficial bacteria like Bifidobacterium and Bacteroides boost vaccine responses is yet to be uncovered. (quadram.ac.uk)
Infectious1
  • Rotavirus is a highly infectious, triple-layered icosahedral, non-enveloped virus particle with a genome of 11 segments of double-stranded Ribonucleic acid (RNA) (Petrie, Estes & Graham 1983). (ojvr.org)
Maternal immunity1
Efficacy6
  • They also stratified studies by economic development of countries, given that vaccine efficacy is often higher in middle- and high-income countries, compared with low-income countries. (medscape.com)
  • Although our results indicated that rotavirus vaccines can provide substantial protection against RVGE during the first 2 years of life, more studies following up the vaccine efficacy for more than 2 years are required," the investigators recommended. (medscape.com)
  • They're assuming, for example, that the vaccine should be used regardless of its efficacy. (foodrenegade.com)
  • On December 14, 2005, the Committee will hear presentations and make recommendations on the safety and efficacy of a Rotavirus Vaccine manufactured by Merck. (blogspot.com)
  • On December 15, 2005, the Committee will hear presentations and make recommendations on the safety and efficacy of ZOSTAVAX (Zoster Vaccine Live [Oka/Merck] ) manufactured by Merck. (blogspot.com)
  • This could be more effective in developing countries, thereby possibly providing a higher overall efficacy for the existing vaccines. (biomedcentral.com)
Tetravalent rhesus1
19981
  • A study conducted from 1998 through 2002 detected rotavirus in 1,155 (31%) of 3,760 specimens tested. (cdc.gov)
Quadrivalent vaccine1
  • Thus, the first licensed rotavirus vaccine (RRV-based quadrivalent vaccine) was designed to cover the epidemiologically important VP7 serotype 1, 2, 3, and 4. (nih.gov)
Withdrawn from the market2
  • The vaccine was withdrawn from the market. (vaccineinjury.info)
  • It can be related to a bad reputation of the previous rotavirus vaccines that were withdrawn from the market or were never introduced to the market due to unsatisfied clinical tests. (am-online.org)
Reassortant1
  • Merck is currently running Phase III trials of a modified version of his quadravalent reassortant vaccine. (blogspot.com)
Deaths3
  • No deaths were recorded among the rotavirus or non-rotavirus groups. (who.int)
  • estimates that for children born in the U.S. from 1994-2013 731,000 deaths would be prevented over the course of their lifetimes from all vaccines, and over 500,000 of those prevented deaths would have been due to diptheria. (effectivealtruism.org)
  • Today, the vaccines are slowly reaching children in low-income countries, but rotavirus still accounts for an estimated 200,000 deaths worldwide every year. (one.org)
Newborns1
  • Newborns, pregnant women or people whose immune systems are weakened may not be eligible for certain vaccines. (nih.gov)
Protective3
Immune system5
  • The project works with industry and academia to study the human immune system and develop vaccines, incorporating every modern-day tool, including artificial intelligence, computational biology, and big data sets. (nautil.us)
  • Based on how the virus behaves when it infects some people, there's a chance a vaccine could dangerously overstimulate the immune system, a reaction called immune enhancement . (nautil.us)
  • Will the Immune System Be Weaker By Relying on a Vaccine? (kidshealth.org)
  • This could potentially replace current adjuvants, substances which are included in vaccines to enhance the immune system response. (quadram.ac.uk)
  • To understand how vaccines work and the foundation of recommendations for their use, it is helpful to understand the basic function of the human immune system. (cdc.gov)
Type of vaccine3
  • Looking forward to a world after polio eradication, a group led by HM Sazzad external icon assess the feasibility of identifying children in Bangladesh who may be at risk for shedding a type of vaccine-derived poliovirus due to underlying immune deficiency. (cdc.gov)
  • This type of vaccine has been in development for about three decades , but is only now being used for COVID-19. (wfyi.org)
  • The oldest type of vaccine. (wikilectures.eu)
Children19
  • Two widely used rotavirus vaccines performed comparably in a meta-analysis , reducing risk of rotavirus gastroenteritis (RVGE) by more than 60% in young children. (medscape.com)
  • Combing through databases Embase, PubMed, the Cochrane Library, and Web of Science using search terms "rotavirus" and "vaccine," they chose 121 randomized clinical trials and cohort and case-control studies that included more than 100 children younger than 5 years. (medscape.com)
  • In an open-label study of 200 children aged 6-59 months who received a single dose of LAIV3, shedding of low titers of at least one vaccine virus was detected on culture in 79 percent of children and was more common among the younger recipients. (wikipedia.org)
  • Before the vaccine, Hib struck about 1 in 200 children younger than age 5. (nih.gov)
  • In an effort to address why the rotavirus vaccine isn't as effective in children in low-income countries as it is in their peers in high- and middle-income countries, researchers found that giving children an extra dose only provides a modest improvement. (umn.edu)
  • This vaccine was rushed into distribution has quickly shown to cause massive intestinal damage and death in a small but vulnerable subset of children. (blogspot.com)
  • The use of DNA vaccines is a new approach to protect animals and children against rotavirus. (ojvr.org)
  • Rotavirus vaccines are being introduced in an increasing number of countries and the oldest cohorts of vaccinated children are approaching 10 years. (biomedcentral.com)
  • At Provida, w e understand that as a parent, you want your children to be healthy, so you may have questions about the vaccines recommended for your child. (providafamilymedicine.com)
  • Learn more about vaccines for school-aged children on the VEC's page for 4- to 6-year-olds or the School-Aged Children Pinterest board . (chop.edu)
  • As a result, the percentage of children under age two who receive no vaccines has quadrupled since 2001 to 1.3 percent in 2013, according to an earlier study cited by the authors. (asapland.com)
  • The authors say they do not know why young children may be more vulnerable to vaccine side effects than older ones but suspect it is because they are less immune or have weaker immune systems. (asapland.com)
  • The analysis was observational and didn't prove that vaccines caused seizures or fevers in young children. (asapland.com)
  • Rotavirus can seriously affect children. (legalexpert.co.uk)
  • Rotavirus is commonly contracted by children. (legalexpert.co.uk)
  • Rotavirus is a virus that can be common amongst children, especially younger ones. (legalexpert.co.uk)
  • Rotavirus is a highly contagious and ubiquitous virus that generally infects children between the ages of six months and two years. (acsh.org)
  • The vaccine that is meant to protect children is now being halted. (newsomelaw.com)
  • Gavi is a global Vaccine Alliance that brings together public and private organisations with a shared goal - to make vaccines more available, accessible and affordable to children who need them the most. (one.org)
Live but weakened2
Development of vaccines2
  • A pioneering bacteriologist, Pittman's research helped the development of vaccines against typhoid, cholera and whooping cough (working with Kendrick & Eldering to strengthen their vaccine). (one.org)
  • Her work led to the development of vaccines against Hib. (one.org)