• gene expression
  • QIAGEN provides a broad range of assay technologies for innate immunity research that enables analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction pathway activation. (qiagen.com)
  • Activation of the innate immune signaling pathways is a highly complex process resulting in the induction of inflammatory gene expression that is central to anti-microbial defenses. (frontiersin.org)
  • Many factors are required to control these responses and in recent years it has been shown that noncoding RNA are major contributors to the control of gene expression within innate immunity. (frontiersin.org)
  • miRNA
  • Much work has been done to show that miRNA are key regulators of the innate immune system and this year alone there has been a number of key papers showing that long noncoding RNA are also essential mediators of the immune response. (frontiersin.org)
  • genes
  • The Human Antifungal Response RT² Profiler PCR Array profiles the expression of 84 key genes involved in the innate immune response to fungi. (qiagen.com)
  • The Human Antiviral Response RT² Profiler PCR Array profiles the expression of 84 key genes involved in the innate antiviral immune response. (qiagen.com)
  • However, individual host resistance genes such as Ipr1, involved in innate immunity for tuberculosis, have been difficult to pinpoint, because of a highly complex multigenic control of host immunity. (rxpgnews.com)
  • functional
  • Progress in these general areas would provide a better understanding of the functional links between innate and acquired immunity, and would lead to new approaches for immunomodulation, vaccine development, and design of broad-spectrum antimicrobial agents. (nih.gov)
  • study
  • I believe this is a field that is in its infancy, which is generating much excitement and this topic within Frontiers will be of much interest to all people involved in the study of innate immunity. (frontiersin.org)
  • studies
  • Full Text PA-97-079 INNATE IMMUNITY NIH GUIDE, Volume 26, Number 24, July 25, 1997 PA NUMBER: PA-97-079 P.T. 34 Keywords: Immunology National Institute of Allergy and Infectious Diseases National Institute of Dental Research PURPOSE The National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Dental Research (NIDR), National Institutes of Health (NIH), invite applications for research studies of the innate immune system. (nih.gov)
  • lead
  • Finding a specific gene in a mouse that has a human equivalent within a highly conserved genetic region suggests that the human equivalent may also be involved in innate immunity to the disease and may further lead to development of diagnostic tests and prevention approaches. (rxpgnews.com)
  • human
  • The Clinical Sciences Research Institute is hosting a seminar entitled 'Glycomics and innate immunity in human disease' from 12:30pm to 1:30pm on Thursday 21 January 2010 in the Large Seminar Room, CSRI, CSB Building UHCW. (warwick.ac.uk)
  • surface
  • When an artificial material makes contact with blood, the first event is a rapid adsorption of plasma protein on the material surface, on top of which the innate immune system is triggered, with potentially detrimental consequences. (diva-portal.org)