• However, in patients with FAP who have had colectomy with ileoanal anastomosis, sulindac or celecoxib may be beneficial in reducing the size and the number of adenomatous polyps in the remaining rectum. (medscape.com)
  • Megacolon operative options include total abdominal colectomy with ileorectal anastomosis, total proctocolectomy with ileostomy, and total proctocolectomy with ileoanal anastomosis, depending on the site of the colon affected. (medscape.com)
  • Cancers of the rectum (in patients who have had subtotal colectomy with ileorectal anastomosis) have been reported despite treatment with sulindac and celecoxib therapy. (medscape.com)
  • This is why subtotal colectomy with ileorectal anastomosis (IRA) is not the preferred surgical procedure. (medscape.com)
  • Total abdominal colectomy with ileorectal anastomosis is the operation of choice of megacolon with normal-sized rectum. (medscape.com)