• pathogenesis
  • NO also reduces pulmonary smooth muscle cell growth and antagonises platelet inhibition, factors which play a key role in the pathogenesis of PAH. (wikipedia.org)
  • JAK2
  • PA remodelling was evaluated in human pulmonary artery endothelial cells (HPAECs) and human pulmonary artery smooth muscle cells (HPASMCs) from patients with IPF in vitro treated with the JAK2 inhibitor JSI-124 or siRNA-JAK2 and stimulated with transforming growth factor beta. (bmj.com)
  • Circulation
  • Dr. Yuan has served on many advisory committees and editorial boards, including Chair of the Respiratory Integrative Biology and Translational Research study section of the National Institutes of Health (NIH), and Chair of the Pulmonary Circulation Assembly of the American Thoracic Society. (wikipedia.org)
  • respiratory
  • In addition, treat respiratory illnesses aggressively in order to minimize or prevent increases in pulmonary bed reactivity from ventilation-perfusion mismatching and/or hypoxia. (medscape.com)
  • Critical Care Med
  • While at the University of California, San Diego, he was the Vice Chair for Research of the Department of Medicine (2007-2010) and Associate Director for Research Training in the Division of Pulmonary and Critical Care Medicine (2003-2010). (wikipedia.org)
  • edema
  • High-altitude pulmonary edema (HAPE) (HAPO spelled oedema in British English) is a life-threatening form of non-cardiogenic pulmonary edema (fluid accumulation in the lungs) that occurs in otherwise healthy mountaineers at altitudes typically above 2,500 meters (8,200 ft). (wikipedia.org)
  • Pulmonary edema Altitude sickness High-altitude cerebral edema (HACE) High-altitude flatus expulsion (HAFE) Pulse oximeter, the instrument to measure oxygen level in blood. (wikipedia.org)
  • cause
  • Fenfluramine was marketed by American Home Products (later known as Wyeth) as Pondimin, but was shown to cause potentially fatal pulmonary hypertension and heart valve problems, which eventually led to its withdrawal and legal damages of over $13 billion. (wikipedia.org)
  • DPB is idiopathic, which means an exact physiological, environmental, or pathogenic cause of the disease is unknown. (wikipedia.org)
  • lungs
  • Lung transplantation or pulmonary transplantation is a surgical procedure in which a patient's diseased lungs are partially or totally replaced by lungs which come from a donor. (wikipedia.org)
  • The first successful transplant surgery involving the lungs was a heart-lung transplant, performed by Dr. Bruce Reitz of Stanford University in 1981 on a woman who had idiopathic pulmonary hypertension. (wikipedia.org)