Hypoxia induci degradation tumor suppressor proteins. Medical search. Frequent questions

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Anatomy15

Cell Line, Tumor Cell Line Tumor Cells, Cultured Cells, Cultured HeLa Cells Fibroblasts Cell Nucleus HCT116 Cells Cell Line, Transformed COS Cells NIH 3T3 Cells Cytoplasm HEK293 Cells Epithelial Cells 3T3 Cells

Organisms8

Mice, Knockout Mice, Nude Mice, Inbred C57BL Mice, Transgenic Mice, Inbred BALB C Papillomaviridae Adenoviridae Drosophila

Diseases31

Anoxia Cell Transformation, Neoplastic Neoplasms Kidney Neoplasms Breast Neoplasms Wilms Tumor Hypoxia, Brain Osteosarcoma Neoplasms, Experimental Carcinoma, Renal Cell Neurofibromatosis 2 Adenocarcinoma von Hippel-Lindau Disease Liver Neoplasms Brain Neoplasms Fetal Hypoxia Carcinoma, Hepatocellular Colonic Neoplasms Carcinoma, Squamous Cell Skin Neoplasms Neoplasm Metastasis Lung Neoplasms Retinoblastoma Disease Progression Neovascularization, Pathologic Glioblastoma Disease Models, Animal Carcinoid Tumor Mammary Neoplasms, Experimental Ovarian Neoplasms Neuroendocrine Tumors

Chemicals and Drugs96

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF Retinoblastoma Protein Proto-Oncogene Proteins c-mdm2 Nuclear Proteins Ubiquitin-Protein Ligases DNA-Binding Proteins Transcription Factors Neurofibromin 2 Adenomatous Polyposis Coli Protein Proto-Oncogene Proteins Cell Cycle Proteins Proteasome Endopeptidase Complex Cyclin-Dependent Kinase Inhibitor p16 PTEN Phosphohydrolase Cyclin-Dependent Kinase Inhibitor p21 RNA, Messenger Hypoxia-Inducible Factor 1, alpha Subunit Ligases Neoplasm Proteins Proteins Cyclins Repressor Proteins Ubiquitin E2F Transcription Factors Tumor Markers, Biological Carrier Proteins RNA, Small Interfering Protein-Serine-Threonine Kinases Recombinant Fusion Proteins E2F1 Transcription Factor Suppressor of Cytokine Signaling Proteins Oncogene Proteins, Viral Transcription Factor DP1 Papillomavirus E7 Proteins Trans-Activators Ubiquitins Hypoxia-Inducible Factor 1 DNA Primers Membrane Proteins WT1 Proteins Tumor Necrosis Factor-alpha Retinoblastoma-Binding Protein 1 Recombinant Proteins Retinoblastoma-Like Protein p107 DNA Intracellular Signaling Peptides and Proteins DNA, Neoplasm Cyclin-Dependent Kinases Oxygen Cysteine Endopeptidases Apoptosis Regulatory Proteins Phosphoric Monoester Hydrolases Phosphoproteins Retinoblastoma-Like Protein p130 Multienzyme Complexes Antigens, Polyomavirus Transforming Adaptor Proteins, Signal Transducing beta Catenin Cytoskeletal Proteins Drosophila Proteins Adenovirus E1A Proteins Neurofibromin 1 Luciferases BRCA1 Protein DNA, Complementary Antineoplastic Agents Adenovirus E1B Proteins Protein Isoforms MicroRNAs Proto-Oncogene Proteins c-myc Enzyme Inhibitors Adenovirus E4 Proteins Cyclin-Dependent Kinase Inhibitor p27 Cyclin-Dependent Kinase 4 Suppressor Factors, Immunologic RNA, Neoplasm Proto-Oncogene Proteins c-bcl-2 Serine Procollagen-Proline Dioxygenase Oncogene Proteins Proto-Oncogene Proteins c-akt Multiprotein Complexes Cullin Proteins Cyclin D1 Ubiquitin Thiolesterase bcl-2-Associated X Protein Cyclin-Dependent Kinase 2 Protein Kinases Ubiquitin-Conjugating Enzymes Glutathione Transferase Basic Helix-Loop-Helix Transcription Factors NF-kappa B Cadherins

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Transfection Blotting, Western Reverse Transcriptase Polymerase Chain Reaction Models, Biological Immunohistochemistry Tumor Burden Immunoblotting Precipitin Tests Immunoprecipitation Polymerase Chain Reaction Neoplasms, Experimental Transplantation, Heterologous Two-Hybrid System Techniques Gene Expression Profiling Microscopy, Fluorescence Cloning, Molecular Flow Cytometry Neoplasm Transplantation Disease Models, Animal Chromatin Immunoprecipitation Fluorescent Antibody Technique Xenograft Model Antitumor Assays Oligonucleotide Array Sequence Analysis DNA Mutational Analysis Mammary Neoplasms, Experimental Chromosome Mapping Blotting, Northern Mutagenesis, Site-Directed Sequence Alignment Gene Knockdown Techniques

Phenomena and Processes74

Genes, Tumor Suppressor Cell Hypoxia Mutation Protein Binding Apoptosis Genes, p53 Gene Expression Regulation, Neoplastic Cell Cycle Transfection Amino Acid Sequence Signal Transduction Base Sequence Promoter Regions, Genetic Genes, Suppressor Phosphorylation Cell Proliferation Transcription, Genetic DNA Damage Down-Regulation Cell Division Protein Structure, Tertiary Transcriptional Activation Gene Expression Regulation Binding Sites RNA Interference Gene Silencing Ubiquitination Gene Deletion DNA Methylation Suppression, Genetic Loss of Heterozygosity G1 Phase Time Factors Cell Survival Cell Aging Proteolysis Gene Expression Ultraviolet Rays Genes, Retinoblastoma Genes, Neurofibromatosis 2 Up-Regulation Phenotype Sequence Homology, Amino Acid Oncogenes Plasmids Genes, Reporter Protein Stability Cell Movement Protein Processing, Post-Translational Protein Transport Cell Differentiation Enzyme Activation Genes, APC Amino Acid Motifs Genes, p16 S Phase Genes, ras Sequence Deletion Acetylation Active Transport, Cell Nucleus Alleles Mutagenesis Gamma Rays Tumor Microenvironment Kinetics Genes, Wilms Tumor Dose-Response Relationship, Drug Point Mutation DNA Repair Cell Death Genetic Vectors Exons Cell Cycle Checkpoints Protein Biosynthesis

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Genes, Tumor Suppressor Von Hippel-Lindau Tumor Suppressor Protein Cell Hypoxia Tumor Suppressor Protein p14ARF Retinoblastoma Protein Cell Line, Tumor Proto-Oncogene Proteins c-mdm2 Molecular Sequence Data Mutation Nuclear Proteins Protein Binding Apoptosis Genes, p53 Cell Line Ubiquitin-Protein Ligases Anoxia Gene Expression Regulation, Neoplastic DNA-Binding Proteins Transcription Factors Neurofibromin 2 Adenomatous Polyposis Coli Protein Cell Cycle Transfection Amino Acid Sequence Signal Transduction Tumor Cells, Cultured Base Sequence Proto-Oncogene Proteins Cell Cycle Proteins Proteasome Endopeptidase Complex Cyclin-Dependent Kinase Inhibitor p16 Promoter Regions, Genetic Genes, Suppressor PTEN Phosphohydrolase Phosphorylation Cyclin-Dependent Kinase Inhibitor p21 RNA, Messenger Cell Proliferation Cell Transformation, Neoplastic Hypoxia-Inducible Factor 1, alpha Subunit Ligases Transcription, Genetic DNA Damage Blotting, Western Down-Regulation Neoplasms Cell Division Neoplasm Proteins Proteins Protein Structure, Tertiary Cyclins Repressor Proteins Transcriptional Activation Ubiquitin Cells, Cultured E2F Transcription Factors Tumor Markers, Biological Gene Expression Regulation HeLa Cells Binding Sites RNA Interference Carrier Proteins Gene Silencing RNA, Small Interfering Reverse Transcriptase Polymerase Chain Reaction Fibroblasts Protein-Serine-Threonine Kinases Recombinant Fusion Proteins E2F1 Transcription Factor Suppressor of Cytokine Signaling Proteins Cell Nucleus Ubiquitination Oncogene Proteins, Viral Gene Deletion Kidney Neoplasms DNA Methylation Suppression, Genetic Models, Biological Transcription Factor DP1 Loss of Heterozygosity Papillomavirus E7 Proteins Trans-Activators Ubiquitins Hypoxia-Inducible Factor 1 Immunohistochemistry Tumor Burden DNA Primers Membrane Proteins WT1 Proteins Tumor Necrosis Factor-alpha Retinoblastoma-Binding Protein 1 Mice, Knockout Recombinant Proteins Breast Neoplasms Retinoblastoma-Like Protein p107 Mice, Nude G1 Phase Time Factors

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