Hypothesis treatment injury or disease spinal cord diseases. Medical search. Frequent questions

Neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, chronic traumatic encephalopathy and multiple sclerosis are characterized by deposition of misfolded proteins leading to a slow progressive loss of neurons, loss of myelin and deficits in brain and spinal cord function. (themiamiproject.org)
Micrograph of a section of the cerebral cortex from a person with Alzheimer's disease , immunostained with an antibody to amyloid beta (brown), a protein fragment that accumulates in amyloid plaques and cerebral amyloid angiopathy . (wikipedia.org)
[3] The proteinopathies include such diseases as Creutzfeldt-Jakob disease and other prion diseases , Alzheimer's disease , Parkinson's disease , amyloidosis , multiple system atrophy , and a wide range of other disorders. (wikipedia.org)
Previously I have written about the roles of glia and microglia in Alzheimer's disease and in spinal cord injury. (anti-agingfirewalls.com)
This blog entry reports on recent research which documents the importance of glial pathology as a general underlying factor in essentially all age related neurodegenerative diseases including Alzheimer's Disease, Parkinson's Disease, advanced spinal degeneration, ALS, multiple sclerosis, and several retinal diseases. (anti-agingfirewalls.com)
In my February 2010 blog entry New views of Alzheimer's disease and new approaches to treating it , I cited evidence for the hypothesis that microglial cell senescence is probably a fundamental cause for AD, a cause upstream of beta amyloid plaque production and the setting in of tau tangles. (anti-agingfirewalls.com)
In the March 2011 blog entry Alzheimer's Disease Update I included a discussion on this hypothesis and on how with aging microglia lose their capability to get rid of beta amyloid via phagocytosis. (anti-agingfirewalls.com)
He answers all our questions about clinical research, including the difficulties, real advances and hopes for new therapies for Alzheimer's disease. (carenity.us)
Alzheimer's disease accounted for 2.5 million people, traumatic brain and spinal cord injuries due to traffic accidents for 1.5 million, strokes for 2 million, epilepsy for 2.3 million, Parkinson's disease for 600,000 and multiple sclerosis for 230,000 (ADREC - Association for the Development of Brain and Spinal Cord Research) (Montreuil, 2005). (carenity.us)
Currently, many therapeutic studies are underway involving patients with mild to mid-stage Alzheimer's disease. (carenity.us)
The CMRR team is active in research and in the publication of scientific articles, particularly in the field of Alzheimer's disease and Dementia with Lewy bodies. (carenity.us)
You've most likely heard of disorders like A.L.S., Parkinson's disease, and Alzheimer's disease, but you may not have heard about an equally tragic condition called Huntington's disease (H.D..D. (mkexpress.net)
According to Dr. Andy Shih, a principal investigator in the Center for Developmental Biology and Regenerative Medicine at Seattle Children's Research Institute, understanding how this vast network regulates blood flow in the brain could hold the key to new treatments for neonatal and childhood neurologic conditions, such as stroke and hypoxia, and issues of aging like dementia and Alzheimer's disease. (reachmd.com)
Alzheimer's disease is a type of dementia that causes problems with memory, thinking and behavior. (globalregenerative.trade)
Restoring neuronal chloride extrusion reverses cognitive decline linked to Alzheimer's disease mutations. (medscape.com)
The potential of blood neurofilament light as a marker of neurodegeneration for Alzheimer's disease. (medscape.com)

This review summarizes the physiological and pathological roles of alpha-synuclein and its implication in Parkinson's disease pathogenesis. (medscape.com)
This paper examines a hallmark symptom of Parkinson's disease, bradykinesia, aiming to elucidate its underlying causes, and emphasizing abnormal behavioral computations mediating motor impairment. (medscape.com)
Might dopamine release deficits prior to neurodegeneration be a pathophysiological hallmark of Parkinson's disease? (medscape.com)
Investigating cortico-striatal beta oscillations in Parkinson's disease cognitive decline. (medscape.com)
How should we be using biomarkers in trials of disease modification in Parkinson's disease? (medscape.com)
The non-specific lethal complex regulates genes and pathways genetically linked to Parkinson's disease. (medscape.com)
PTPA variants and the risk for Parkinson's disease in diverse ancestry populations. (medscape.com)

We comprehensively examined cases of human claustrum lesions to assess their support for various hypotheses of function. (researchgate.net)
7 Nodular white matter lesions are seen on imaging and most ischaemic changes occur in the basal ganglia, periventricular white matter and temporal lobes, 1 , 8 and a family with spinal cord lesions in the presence of a novel NOTCH 3 mutation has been described. (bmj.com)
AFM is an illness that's characterized by the sudden onset of flaccid weakness in one or more extremities and also by distinct longitudinal gray matter lesions in the spinal cord. (cdc.gov)

We wanted to determine if treatment with glyceryl triacetate alters central nervous system (CNS) lipid content in mice subjected to experimental autoimmune encephalomyelitis (EAE), an autoimmune multiple sclerosis model. (und.edu)

These data test the hypothesis that treatment may alter CNS lipid metabolism in mice subjected to EAE. (und.edu)
Since there is evidence that inflammation plays an important role in the spasticity seen in patients with SCI, there is necessity for future research, both at the experimental and also at the clinical level, in order to test the hypothesis of a close correlation between the anti-inflammatory effect of acupuncture and the successful treatment of spasticity in patients with SCI. (eexot-journal.com)

The development of pathology at the mobile segment next to a lumbar or lumbosacral spinal fusion has been termed adjacent segment disease. (scienceopen.com)
Histological analyses of the lumbosacral spinal cord revealed that Bxt markedly delayed the early motor-neuron degeneration occurring at presymptomatic stages in ALS-transgenic mice. (frontiersin.org)

Progressive spinal degeneration with age is also thought to be a major contributor. (scienceopen.com)
drugs that act on beta-amyloid plaques (showing few results, studies have stopped) and ongoing studies investigating the anti-tau hypothesis (passive immunotherapy) and acting on neurofibrillary degeneration (results are still pending). (carenity.us)
to better understand the disease and especially the mechanisms involved in degeneration. (carenity.us)
Sciatic nerve transection, early after birth, results in significant degeneration of spinal motoneurons as well as sensory neurons present in the dorsal root ganglia. (hindawi.com)

Stem cell therapies can benefit as a regenerative medicine for patients that have or been diagnosed with disease that affect the mid part of the brain, strokes and heart disease, joint disease and injuries to the spinal cord. (wikipedia.org)
Single- or repetitive-pulse stimulation of the brain causes the spinal cord and peripheral muscles to produce neuroelectrical signals known as motor evoked potentials (MEPs). (medscape.com)
Neurogenic myositis ossificans is the formation of heterotopic bone in the periarticular soft tissues of patients who have sustained a severe injury to the brain or spinal cord. (the-medical-dictionary.com)
When it occurs outside of the brain or spinal cord, it is a peripheral neuropathy [1]. (spinalresearch.com.au)
Microglia are a type of glial cell that are the resident macrophages of the brain and spinal cord , and thus act as the first and main form of active immune defense in the central nervous system (CNS). (anti-agingfirewalls.com)
Microglia (and astrocytes , another type of glial cells) are distributed in large non-overlapping regions throughout the brain and spinal cord. (anti-agingfirewalls.com)
[3] The brain and spinal cord are considered "immune privileged" organs in that they are separated from the rest of the body by a series of endothelial cells known as the blood-brain barrier , which prevents most infections from reaching the vulnerable nervous tissue. (anti-agingfirewalls.com)
In addition, treatment significantly increased total brain phosphatidylserine and choline glycerophospholipid as well as GD3 ganglioside levels in EAE mice compared to control-treated EAE mice. (und.edu)
We also determined how treatment altered brain lipid levels within the myelin fraction, the membrane fraction lost in EAE. (und.edu)
Huntington's disease is an unfortunate and somewhat rare genetic brain disorder that currently affects about 30,000 Americans. (mkexpress.net)
The human trial began in late 2015 and utilized the drug IONIS-HTTRx, which was injected into the spinal fluid to reach the patient's brain. (mkexpress.net)
In general, cerebrovascular disease is a definition used to describe a heterogeneous group of pathological conditions that share a focal dysfunction in the brain tissue, due to an imbalance between the supply and requirements of oxygen and other substrates. (institutchiaribcn.com)
Whether brain capillary pericytes constrict and dilate capillaries has remained a controversial hypothesis since they were discovered," Shih said. (reachmd.com)
Outside the brain, norepinephrine is used as a neurotransmitter by sympathetic ganglia located near the spinal cord or in the abdomen , as well as Merkel cells located in the skin. (wikipedia.org)
Purpose Although functional MRI is widely applied in the brain, fMRI of the spinal cord is more technically demanding. (researchgate.net)
Repeated mild traumatic brain injury triggers pathology in asymptomatic C9ORF72 transgenic mice. (medscape.com)
Neurosurgical pathologies are a set of conditions that affect the brain, spinal cord, and cranial pairs requiring medical and surgical management. (bvsalud.org)

This patient had various complications including adjacent segmental disease, vertebral subluxation, and junctional fractures on radiographs and magnetic resonance images. (scienceopen.com)
Different injuries were identified: multiple fractures, crushing, amputation, perforation of soft tissues, inhalation of dust and establishment of chronic conditions through stress. (biomedcentral.com)
Types 2 and 3 must be capable of offering autonomous rehabilitation services, including care in situations consisting of exposed fractures, peripheral nerve injuries, amputations, burns. (biomedcentral.com)

In addition, noninfectious etiologies such as neuroinflammatory conditions or spinal vascular disease can result in a clinical and radiographic picture that overlaps with that of AFM caused by infection ( 5 - 7 ). (cdc.gov)
Twelve patients had suffered cerebral trauma, seven trauma to the spinal cord, five vascular disease and five complications as a result of a lengthy stay in intensive care. (the-medical-dictionary.com)

Researchers are using knowledge gained from conducting acute injury studies to test new hypotheses about the cause and treatment of these chronic disorders. (themiamiproject.org)
There is wide agreement that excessive microglial activation is a key process in nervous system disorders involving release of strong pro-inflammatory cytokines, cytokines which can trigger worsening of multiple disease states. (anti-agingfirewalls.com)
This report describes the role of neuroprotection in acute disorders such as stroke and injuries of the nervous system as well as in chronic diseases such as neurodegenerative disorders because many of the underlying mechanisms of damage to neural tissues are similar in all these conditions and several products are used in more than one disorder. (researchandmarkets.com)
Historically, manipulation can trace its origins from parallel developments in many parts of the world where it was used to treat a variety of musculoskeletal conditions, including spinal disorders. (drjohnduppenthaleronline.com)
One of the downsides to the conventional treatment for Huntington's disease and other cognitive disorders is that they commonly have many side effects, such as fatigue, insomnia , appetite and mood changes, etc. (mkexpress.net)
For reasons that are still unclear, some Alpha-2 drugs, such as guanfacine , have also been shown to be effective in the treatment of anxiety disorders and ADHD . (wikipedia.org)
Due to the increased co-prevalence of these two disorders, the effect of pharmacological agents used for the treatment of diabetes mellitus on bone metabolism has assumed importance. (umc.edu)
Neurological disorders arising from injuries to the central nerve system may compromise the nutritional status depending on the affected area, having sometimes a detrimental effect on the physical and cognitive capacities required for a proper nutrition. (bvsalud.org)

This therapeutic effect is multifactorial, including the regulation of the activity of various endogenic biological mediators, the regeneration of nerve fibres and stem cells and the inhibition of inflammation, neural apoptosis and oxidative stress in the injured spinal cord. (eexot-journal.com)
Our findings thus suggest that exposure to GWI-related agents may converge on similar targets with roles in inflammation, neurotransmitter and lipid metabolism, and detoxification which may have impacts on neurodegenerative-like disease and oxidative stress in Veterans with GWI. (cdc.gov)

GLP-1 receptor agonists which have been approved for the treatment of type 2 diabetes mellitus have been shown to improve trabecular bone mass in animal studies. (umc.edu)

Centers for Disease Control and Prevention. (cdc.gov)
The Centers for Disease Control and Prevention and AFM partners are focused on answering key questions about AFM epidemiology and mechanisms of disease. (cdc.gov)
Number of confirmed cases of acute flaccid myelitis reported to the Centers for Disease Control and Prevention, United States, August 1, 2014-June 30, 2020. (cdc.gov)
I'm Commander Ibad Khan and I'm representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communication Branch at the Centers for Disease Control and Prevention. (cdc.gov)
Dr. Janell Routh is a medical officer on the acute flaccid myelitis team at the Centers for Disease Control and Prevention. (cdc.gov)
Adriana Lopez is an epidemiologist on the acute flaccid myelitis team at the Centers for Disease Control and Prevention. (cdc.gov)
Finally, Dr. Manisha Patel is the acute flaccid myelitis team lead at the Centers for Disease Control and Prevention. (cdc.gov)

Since nearly all chronic inflammation stems from to experience more considerable pain with leg it can develop after an injury. (shoutblock.com)
Background: Passive training of specific locomotor muscle groups by means of neuromuscular electrical stimulation (NMES) might be better tolerated than whole body exercise in patients with severe chronic obstructive pulmonary disease (COPD). (bmj.com)
Knee extensor strength and endurance, whole body exercise capacity, and health related quality of life (Chronic Respiratory Disease Questionnaire, CRDQ) were assessed. (bmj.com)
Exercise intolerance is a hallmark of chronic obstructive pulmonary disease (COPD) and is commonly associated with reduced quality of life and increased utilisation of healthcare resources. (bmj.com)
2. Masri R, Keller A. Chronic pain following spinal cord injury. (eexot-journal.com)
Our results support proof of principle of genetic differences in the chronic effects of GWI-related exposures and may reveal why the disease has persisted in many of the now aging Gulf War veterans. (cdc.gov)

The provider places their finger on the caused by this disease, its advised that and social anxiety seem to be particularly based on the pain this inflammation produces, Cheapest Place To Get Celecoxib. (shoutblock.com)
8. Ren Y, Young W. Managing inflammation after spinal cord injury through manipulation of macrophage function. (eexot-journal.com)
Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration. (eexot-journal.com)

IMI2-PainCare-BioPain-RCT2 will focus on human spinal cord and brainstem a. (researchgate.net)
Brainstem injuries can, for example, infiltrate any of the cranial nerves that innervate facial and head structures, having an effect on nutrition, due to the fact that the patient is often unable to eat without running the risk of directing food or liquid into the lungs 2 . (bvsalud.org)

Each year, 10 million people worldwide survive the neurologic injury associated with a stroke. (jneurosci.org)
The surgeries did not resolve her problems of spinal instability and neurologic complications. (scienceopen.com)
Neurologic injuries following long instrumentation are often serious and difficult to address with surgery alone. (scienceopen.com)

Unfortunately, there is no known cure - however, research suggests supplementation may help manage some symptoms of Huntington's disease. (mkexpress.net)
So what are the signs and symptoms of Huntington's disease, and what treatment options are out there to help curb and potentially reverse this debilitating condition? (mkexpress.net)
What Is Huntington's Disease? (mkexpress.net)
According to the Huntington's Disease Society of America, H.D..D. is called a "family disease" because children who have a parent with H.D..D. have about a 50/50 chance of carrying the faulty gene themselves. (mkexpress.net)
As of 2008, some progress was made when the U.S. Food and Drug Administration approved the drug tetrabenazine to treat involuntary writhing movements of H.D..D. (chorea), making it the very first Huntington's disease drug approved for use in the U.S. (mkexpress.net)
In 2017, an experimental drug was introduced in a human trial involving 46 patients with early Huntington's disease. (mkexpress.net)
Although more data and trials are needed, animal research showed some motor function was recovered in those experiments and suggested this experimental drug could change the course of Huntington's disease. (mkexpress.net)
What else besides medications might be able to help reduce symptoms of Huntington's disease? (mkexpress.net)
Genetic topography and cortical cell loss in Huntington's disease link development and neurodegeneration. (medscape.com)

Il s'agit d'une étude rétrospective descriptive et analytique, multicentrique portant sur des patients de moins de 5ans pris en charge pour une affection neurochirurgicale de Janvier 2019 à Décembre 2021 à Libreville. (bvsalud.org)

A novel side note to the study is that it's the first piece of peer-reviewed, published literature that features Spinal Research's own definition of the vertebral subluxation . (spinalresearch.com.au)
Adjacent segmental disease, junctional fracture, and vertebral subluxation are familiar complications following instrumented spinal fusion surgeries for osteoporotic spines. (scienceopen.com)

Spinal cord injury: pathophysiology, multimolecular interactions, and underlying recovery mechanisms. (eexot-journal.com)
5. Alizadeh A, Dyck SM, Karimi-Abdolrezaee S. Traumatic spinal cord injury: an overview of pathophysiology, models and acute injury mechanisms. (eexot-journal.com)
7. Couillard-Despres S, Bieler L, Vogl M. Pathophysiology of traumatic spinal cord injury. (eexot-journal.com)

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive weakness and muscle atrophy related to the loss of upper and lower motor neurons (MNs) without a curative treatment. (frontiersin.org)
Amyotrophic lateral sclerosis (ALS) is the most common disease affecting the motor neurons (MNs) with an annual incidence that ranges from 2 to 4 cases per 100,000 people. (frontiersin.org)

That same blog entry also cites publications arguing that, t o a considerable extent, aging-related neurodegenerative diseases appear to depend on the same underlying mechanisms. (anti-agingfirewalls.com)
We are generally a effective test among platelets in proteins and isotope capacity hearts with angina system conditions to define for the Indirect teaching clinical oils under Myocardial mechanisms with everything cells of Carboxylic disease and endovascular slow compounds to be whether infection Method is intermediate and is improperly to warm-blooded class function plasma. (seabaygame.com)
Despite recent findings regarding the functional implications of TRPM4 in cardiac diseases, the molecular and cellular mechanisms leading to altered conduction are poorly understood. (frontiersin.org)
Introduction: Bisphosphonates (BP) are effective drugs in the prevention and treatment of various bone pathologies, acting in the regulation of osteoclast function through different mechanisms. (bvsalud.org)

Stem Cell therapies, here referred to as therapies employing non-hematopoietic, mesenchymal stem cells, have a wide range of potential therapeutic benefits for different diseases, most of which are currently investigated in clinical trials. (wikipedia.org)
The present narrative literature review aims to present recent research data in relation to the therapeutic effect of acupuncture on patients with SCI, and more specifically on the reduction of the inflammatory response and the spasticity after an injury of the spinal cord. (eexot-journal.com)

The paracrine activity of stem cells, i.e. the stem cell secretome, has been found to be the predominant mechanism by which stem cell-based therapies mediate their effects in degenerative, auto-immune and/or inflammatory diseases. (wikipedia.org)
On the contrary, reconnection of transected stumps by using biocompatible sealants may significantly facilitate the process, as well as taking the advantage of employing the adhesive as scaffold to engraft stem cells, as well as neurotrophic substances, to the injury site. (hindawi.com)
Critical to the hypothesis is the experimental fact that human endometrial-derived stem cells (hEnSCs) as multipotent accessible source of cells are known as useful cell candidates in the field of nerve tissue engineering. (scirp.org)

Glycine receptors are known to play a key role in inhibitory neurotransmission in the spinal dorsal horn and have therefore been c. (researchgate.net)

The lack of fast neurological expertise in regions with underserved infrastructure poses a major barrier for state-of-the-art care of patients with acute neurological diseases and leads to disparity in provision of health care. (biomedcentral.com)
The main purpose of ANNOTeM (acute neurological care in North East Germany with telemedicine support) is to establish effective and sustainable support structures for evidence based treatments for stroke and other neurological emergencies and to improve outcome for acute neurological diseases in these rural regions. (biomedcentral.com)
Unfortunately, most neurological diseases peak at higher age, which means that rural areas with typically elderly populations face a particular challenge in providing appropriate care. (biomedcentral.com)
ANNOTeM (acute neurological care in North-East Germany with telemedicine support) aims to improve health care by use of telemedicine for acute time-dependent neurological diseases beyond stroke, in particular coma/status epilepticus, meningoencephalitis, and spinal cord injury, and therefore establish sustainable structures for implementation of evidence based treatments in underserved areas in North-East Germany. (biomedcentral.com)

Our service noted, in recent years, a significant increase in demand for guidance on complications related to the use of BP and dental treatment. (bvsalud.org)

Tenderness out of the gallbladder within minutes after the introduction of invasive diagnostic proce-dures in patients with anemia are especially liable to cause seizures in term infants to cialis for reasons what are taking every h a fourth hypothesis concerned with maintaining muscle strength. (elastizell.com)
Treatment with medications or sometimes surgery can control seizures for the majority of people with epilepsy. (globalregenerative.trade)
Some people require lifelong treatment to control seizures, but for others, the seizures eventually go away. (globalregenerative.trade)

Although anatomical repair of spinal roots and other lesioned plexus components constitute the primary approach, additional strategies are necessary to enhance neuroprotection and to improve the regenerative response of severed neurons. (hindawi.com)

Therefore, we tested the hypothesis that a B-lymphocyte response to stroke could contribute to the onset of dementia. (jneurosci.org)

Neuronal survival, axonal regeneration, and ultrastructural changes at ventral spinal cord were also investigated. (hindawi.com)
Importantly, exogenous treatment with neurotrophins transiently rescues a significant number of neurons, leading to the possibility of axonal regrowth and regeneration [ 19 , 20 ]. (hindawi.com)

Conventional treatment is varied, but "pharmacological treatment is recognized as the first-line approach based on current clinical trial recommendations [2]. (spinalresearch.com.au)
In the private sector, pharmaceutical laboratories may call on neuropsychologists to develop clinical research protocols and evaluate the effects of new treatments. (carenity.us)
Her survey will assess interest in receiving evidence based pediatric obesity prevention and treatment in primary care settings, as well as perceived barriers and facilitators to participating in pediatric obesity focused clinical trials research. (umc.edu)
Pediatric primary care providers (n = 36) will participate in focus groups to examine knowledge of pediatric overweight and obesity expert prevention and treatment recommendations, as well as needs and interest for an obesity specific practice network and pediatric obesity clinical trials research. (umc.edu)

11,12 In a study, 147 patients with ED, who were under treatment with sildenail, were asked to replace their medication by tadalafil. (org.pk)
7,14,15 We evaluated the hypothesis that tadalafil could yield better results when used on a daily basis rather than on an on-demand basis for the treatment of patients with ED. Also, we evaluated the possible time-dependent effect of tadalafil in the treatment of ED. (org.pk)
Conservative treatments should always be contemplated as an alternative method for patients with poor bone stock. (scienceopen.com)
You will need a hot water bath of injury in RA patients. (shoutblock.com)
At our centre we frequently detect the presence of images of Leukoaraiosis in the white matter on MR T2-weighted axial sequences, especially of degree 1 and seldom of degree 2, in patients diagnosed of Filum Disease or Neuro-Cranio-vertebral group of conditions - in at least the 45% of our database and in all age groups. (institutchiaribcn.com)
Non-celiac gluten sensitivity (NCGS) is a syndrome diagnosed in patients with symptoms that respond to removal of gluten from the diet, after celiac disease and wheat allergy have been excluded. (mdpi.com)
The recommendations for vaccinating HCP are presented by disease in two categories: 1) those diseases for which vaccination or documentation of immunity is recommended because of risks to HCP in their work settings for acquiring disease or transmitting to patients and 2) those for which vaccination might be indicated in certain circumstances. (cdc.gov)
Dr Tamara Jamaspishvili is a research pathologist, translational research scientist focusing on developing, evaluating, validating, and applying tissue-based prognostic and predictive biomarkers and models for improved disease prognostication and management of cancer patients. (upstate.edu)
Spinal cord injury (SCI) is a serious pathological condition, which causes significant morbidity and mortality in patients who are suffering from it. (eexot-journal.com)
to assess the nutritional status of neurological patients in physiotherapy treatment. (bvsalud.org)
Conclusion: Dentists should advise their patients about the use of BP and the implications for oral health and treatments. (bvsalud.org)
These patients must have periodic consultations for evaluation and early detection of osteonecrosis associated to BP for adequate treatment. (bvsalud.org)
Most patients had been referred to our service seeking for dental treatment or orientation about dental procedures and systemic conditions. (bvsalud.org)
Patients received orientation concerning the use of BP and the implications on oral health and treatments. (bvsalud.org)
Between the years of 2011 and 2012, 26 patients who used BP were treated in the Service of Oral and Maxillofacial Surgery of the Erasto Gaertner Hospital ( table I ). The following reasons accounted for their appointments: orientation about dental treatment, physician indication and dental health orientation. (bvsalud.org)
Méthodes: Etude rétrospective, descriptive, monocentrique, colligeant les patients hospitalisés pour prise en charge d'une brèche ostéoméningée (BOM) et explorés par le couple TDM/IRM, du 1er janvier 2012 au 31 Décembre 2021. (bvsalud.org)

Experimentally, a well-accepted model to mimic axotomy injury retrograde repercussion to spinal neurons is the neonatal peripheral nerve axotomy [ 13 - 18 ]. (hindawi.com)

It is especially detected in people with some mental disorder, and in those with diseases associated with neurological damages or symptoms of dementia. (institutchiaribcn.com)
Described by Joutel et al , 3 cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a Mendelian form of hereditary small-vessel disease and vascular dementia. (bmj.com)

It is a disease that becomes progressive. (institutchiaribcn.com)
however, the original description of using tendon transfer for the treatment of progressive flatfoot deformity is attributed to Goldner in 1974. (medscape.com)

Review the definition, etiology, incidence, and risk factors associated with as well as potential treatment options. (scienceopen.com)
Incidence of symptomatic adjacent segment disease is lower, however, ranging from 5.2 to 18.5% during 44.8 to 164 months of follow-up observation. (scienceopen.com)
Global incidence and prevalence of traumatic spinal cord injury. (eexot-journal.com)
Leur incidence en Afrique sub-saharienne et plus particulièrement au Gabon est mal connue. (bvsalud.org)

While it is established that cardiovascular disease (CVD) is typically associated with middle or old age, atherosclerosis often initiates in early childhood when deposits of cholesterol form fatty streaks in the intima of large arteries. (umc.edu)

These studies demonstrate that acetate supplementation reduced disease progression, altered CNS and myelin lipid content, and influenced CNS and myelin protein content in mice subjected to EAE. (und.edu)

It is acknowledged that spinal manipulation is and was widely practiced in many cultures and often in remote world communities such as by the Balinese of Indonesia, the Lomi- Lomi of Hawaii, in areas of Japan, China and India, by the shamans of Central Asia, by sabodors in Mexico, by bone setters of Nepal as well as by bone setters in Russia and Norway. (drjohnduppenthaleronline.com)
Historical reference to Greece provides the first direct evidence of the practice of spinal manipulation. (drjohnduppenthaleronline.com)
Claudius Galen (131-202 CE), a noted Roman surgeon, provided evidence of manipulation including the acts of standing or walking on the dysfunctional spinal region. (drjohnduppenthaleronline.com)

proteinopathic adj ), or proteopathy , protein conformational disorder , or protein misfolding disease , is a class of diseases in which certain proteins become structurally abnormal, and thereby disrupt the function of cells , tissues and organs of the body. (wikipedia.org)
Pedicle screw instrumentation for treating spinal disorder is becoming increasingly widespread. (scienceopen.com)
He also studied valproate and carbamazepine as a treatment for bipolar disorder. (nih.gov)

Hippocrates (460-370 BCE), who is often referred to as the father of medicine, was the first physician to describe spinal manipulative techniques. (drjohnduppenthaleronline.com)

Some of the most commonly seen rheumatoid arthritis symptoms include rheumatoid arthritis to reduce about the symptoms, causes, and treatment of arthritis, make sure to include foods that are rich in cure for this autoimmune knee pain including the symptoms, causes, and is to damage to the joints. (shoutblock.com)

The etiology of central nerve injury can vary from a congenital anomaly, vascular accidents, spinal cord injuries to degenerative illnesses. (bvsalud.org)

In addition, we performed experiments to determine whether treatment had an effect on disease progression, protein levels of enzymes involved in lipid metabolism, cytoskeletal structure, and myelin structure. (und.edu)
This suggests treatment may alter myelin structure, and this was also shown in the FluoroMyelinTM staining. (und.edu)

Surgery may be hazardous with potential haemorrhage, neurovascular injury, iatrogenic fracture and osteochondral injury. (the-medical-dictionary.com)
We established that early surgery, within 24 months of injury, was neither complicated by peri-operative fracture nor by the early recurrence of neurogenic myositis ossificans. (the-medical-dictionary.com)

Though we lack RCT's looking into chiropractic care and each of these, case report data (among other research or hypothesis work) does indicate that restoring optimal function to the nervous system can impact these areas in some cases. (spinalresearch.com.au)

Initially reported to occur rarely, it is now considered a potential late complication of spinal fusion that can necessitate further surgical intervention and adversely affect outcomes. (scienceopen.com)
In the neonate, such injuries are even more harmful, since surgical treatment is limited and neuronal loss is particularly enhanced by neurotrophic factors deprivation. (hindawi.com)
[ 5 ] This was followed by articles by Fowler and Williams, who each presented posterior tibial tendinitis as a syndrome, with the suggestion that surgical intervention may play a role in the treatment of this condition. (medscape.com)

[20] They have been most thoroughly studied with regard to prion disease , and are referred to as protein strains . (wikipedia.org)
To test this hypothesis, we used Western blot analysis to measure protein levels of enzymes involved in lipid synthesis and lipid breakdown. (und.edu)
EAE resulted in a significant increase of cytosolic phospholipase A2 protein levels, but treatment returned those levels back to control to suggest treatment may modulate cytosolic phospholipase A2-mediated lipid breakdown. (und.edu)
In addition, we found treatment significantly decreased phosphorylated acetyl-CoA carboxylase protein levels in EAE mice, an enzyme involved in fatty acid synthesis. (und.edu)
The results of the trial confirmed the drug lowered the level of the toxic disease-provoking protein, huntingtin. (mkexpress.net)

Both diagnosis and treatment of neurological emergencies require neurological expertise and are time-sensitive. (biomedcentral.com)
The goal of this project is to develop and characterize aerolysin-based nanopores as sensing devices to be applied for genome sequencing, proteomic analysis and disease diagnosis. (epfl.ch)
Earlier diagnosis and intervention methods are improving dramatically, and treatment options and sources of support can improve quality of life. (globalregenerative.trade)

Noradrenaline itself is widely used as an injectable drug for the treatment of critically low blood pressure. (wikipedia.org)
[ 10 ] A widely accepted classification system, proposed by Johnson in 1989 and modified by Myerson in 1997, clarified treatment recommendations on the basis of the severity of the PTT dysfunction and the adaptation of the foot to collapse of the medial longitudinal arch. (medscape.com)

This suggests treatment may not alter all EAE disease pathologies. (und.edu)
Les pathologies neurochirurgicales sont un ensemble d'affections qui touche le cerveau, la moelle épinière, et les paires crâniennes nécessitant une prise en charge médico-chirurgicale. (bvsalud.org)
Les pathologies neurochirurgicales sont en fréquentes dans notre contexte. (bvsalud.org)

It normally occurs in the first weeks or months after the injury. (the-medical-dictionary.com)

The breakthrough with this research and trial could present further opportunities for other neurodegenerative diseases. (mkexpress.net)
After signaling the research treatment, you include three systems:( 1) IBIDS Consumer Database,( 2) Full IBIDS Database, or( 3) Peer Reviewed interventions So. (seabaygame.com)

The erectile function domain of the International Index of Erectile Function was evaluated initially at the baseline and then at 24 weeks after treatment. (org.pk)
Treatment with daily tadalafil was associated with a significantly higher erectile function domain score compared to the on-demand use. (org.pk)
A change in body function or cell structure that results in an abnormal or harmful effect, which might lead to disease or health problems. (cdc.gov)
A clear understanding of the normal function of the PTT and the static restraints of the medial longitudinal arch is essential to understanding the operative and nonoperative treatment options for AAFD. (medscape.com)

Anatomy2

Diseases3

Chemicals and Drugs3

Alzheimer's16

Parkinson's7

Lesions3

Multiple sclerosis1

Test the hypothesis2

Lumbosacral spinal2

Degeneration4

Brain17

Fractures3

Vascular disease2

Disorders8

Oxidative stress2

Diabetes mellitus1

Centers for Diseas7

Chronic6

Inflammation3

Brainstem2

Neurologic3

Huntington's9

20191

Vertebral subluxation2

Pathophysiology3

Amyotrophic lateral s2

Mechanisms4

Therapeutic2

Stem cells3

Dorsal1

Neurological diseases4

Complications1

Seizures3

Anatomical1

Stroke1

Axonal2

Clinical4

Patients16

Neurons1

Dementia2

Progressive2

Incidence4

Cardiovascular1

Supplementation1

Manipulation3

Disorder3

Describe1

Arthritis1

Etiology1

Myelin2

Fracture2

Nervous system1

Surgical3

Protein5

Diagnosis3

Widely2

Pathologies3

Occurs1

Research2

Function4