Chromophil cells therefore belong to the group of APUD (amine precursor uptake and decarboxylation) cells. (wikipedia.org)
The detailed study of neuroendocrine cells by Pearse ( 3 , 4 ) led to the development of the concept of amine precursor uptake and decarboxylation (APUD). (basicmedicalkey.com)
Trk-like (A-B-C) proteins which are secreted by the cells making up the sub-population of the endocrine cells carry out the neurotrophin synthesis, amine and/or peptide storage as well as the regulation of the blood circulation of the gastrointestinal tract. (fusabil.org)
Thyroid2
These cells are scattered throughout the whole body, but particularly in glands such as the hypothalamus, hypophysis, thyroid, parathyroid and pancreas. (wikipedia.org)
The steroid-producing endocrine cells of the adrenal cortex, ovary, and testis, as well as the thyroid hormone-producing follicular cells in the thyroid gland, do not form part of the DNS. (basicmedicalkey.com)
Pituitary1
Anterior pituitary cells that produce GROWTH HORMONE. (wakehealth.edu)
Endocrine5
The DNS consists of a wide variety of cells that are present in the central and peripheral nervous system and in many classic endocrine organs ( Table 11.1 ). (basicmedicalkey.com)
Feyrter ( 2 ) considered the clear cells of the gastrointestinal tract to be peripheral endocrine or paracrine cells. (basicmedicalkey.com)
Although the APUD concept provided a unifying theory for explaining some endocrine diseases and ectopic hormone productions, the hypothesis that the cells were all of neural crest origin, as postulated by Pearse, was later disproved by the experiments of LeDouarin ( 5 ) and others. (basicmedicalkey.com)
Gastrointestinal endocrine cells are distributed in the mucosa of the gastrointestinal tract and they synthesize various kinds of gastrointestinal hormones. (fusabil.org)
The existence of endocrine cells has been immunohistochemically demonstrated in the gastrointestinal tract mucosa of different fish species 8 - 18 . (fusabil.org)
Extracellular space2
Paracrine regulation refers to the production of amines and hormones by cells that exert a local effect on the target cells by diffusion through the extracellular space. (basicmedicalkey.com)
In pancreatic islets, GLUT2 allows a rapid equilibration of glucose between the extracellular space and the interior of the cells and it may play a crucial role in the glucose signaling mechanism leading to insulin secretion (43). (justia.com)
Neurons1
insulin-secreting cells, the basolateral membrane of intestinal and kidney absorptive cells, in hepatocytes and in a subset of neurons (21,31,44). (justia.com)
Immunohistochemical1
The current neuroendocrine classification of cells and tumors uses immunohistochemical (IHC), ultrastructural, and molecular biologic features to define members of the DNS ( 6 , 7 and 8 ). (basicmedicalkey.com)
Amines1
These cells share the ability to produce many biologically active amines, peptides, and other substances. (basicmedicalkey.com)