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  • gonadotropin-releasi
  • Gonadotropin-releasing hormone (GnRH) also known as gonadoliberin, and by various other names in its endogenous form and as gonadorelin (INN) in its pharmaceutical form, is a releasing hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. (wikipedia.org)
  • cortisol
  • The variation in cortisol levels according to disease type and severity, as well as variation within the same patient, hampers the establishment of a clear threshold below which CIRCI occurs. (wikipedia.org)
  • In addition to quantifying adrenal insufficiency, the test can distinguish whether the cause is adrenal (low cortisol and aldosterone production) or pituitary (low ACTH production). (wikipedia.org)
  • citation needed] Interpretation for primary adrenal insufficiency, Addison's disease In Addison's disease, baseline cortisol is well below 10 µg/dl and rises no more than 25 percent. (wikipedia.org)
  • tumor
  • Ando S, Sarlis NJ, Krishnan J, Feng X, Refetoff S, Zhang MQ, Oldfield EH, Yen PM. Aberrant alternative splicing of thyroid hormone receptor in a TSH-secreting pituitary tumor is a mechanism for hormone resistance. (springer.com)
  • Ando S, Sarlis NJ, Oldfield EH, Yen PM. Somatic mutation of TRbeta can cause a defect in negative regulation of TSH in a TSH-secreting pituitary tumor. (springer.com)
  • Conversely, acromegaly and gigantism are conditions of GH and IGF-1 excess usually due to a pituitary tumor, and are characterized by overgrowth and tall stature. (wikipedia.org)
  • hypogonadism
  • Acquired causes of secondary hypogonadism include reversible causes such as functional hypothalamic amenorrhea, drugs, chronic illnesses, and irreversible causes such as central nervous system insults (trauma, irradiation, and intracranial tumors). (springer.com)
  • deficiency
  • Increased CRH production has been observed to be associated with Alzheimer's disease and major depression, and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia. (wikipedia.org)
  • liver
  • Almost always the endocrine manifestations occur in a patient with widespread disease involving the lungs, skin or liver. (bmj.com)
  • A separate system of scoring the histological features of nonalcoholic fatty liver disease (NAFLD) called the NAFLD Activity Score (NAS) was used. (clinicaltrials.gov)
  • and either a decrease in the activity score for nonalcoholic fatty liver disease to a score of 3 or less or a decrease in the activity score of at least 2 points, with at least a 1-point decrease in either the lobular inflammation or steatosis score. (clinicaltrials.gov)
  • Cirrhosis is most commonly caused by alcohol, hepatitis B, hepatitis C, and non-alcoholic fatty liver disease. (wikipedia.org)
  • Non-alcoholic fatty liver disease has a number of causes, including being overweight, diabetes, high blood fats, and high blood pressure. (wikipedia.org)
  • Evidence of mild or severe liver disease may be found. (wikipedia.org)
  • genetic
  • Hashimoto's disease during interferon-alpha therapy in a patient with pre-treatment negative anti-thyroid autoantibodies and with the specific genetic susceptibility to the thyroid disease. (nel.edu)
  • Martocchia A, Labbadia G, Paoletti V, Gargano S, Grossi A, Trabace S, Musca A, Falaschi P. Hashimoto's disease during interferon-alpha therapy in a patient with pre-treatment negative anti-thyroid autoantibodies and with the specific genetic susceptibility to the thyroid disease. (nel.edu)
  • Hypothalamic disease is a disorder presenting primarily in the hypothalamus, which may be caused by damage resulting from malnutrition, including anorexia and bulimia eating disorders, genetic disorders, radiation, surgery, head trauma, lesion, tumour or other physical injury to the hypothalamus. (wikipedia.org)
  • hyperthyroidism
  • Therefore, a correct diagnosis is fundamental in order to prevent dramatic consequences, such as improper thyroidectomy in patients with secondary hyperthyroidism due to TSHoma or unnecessary pituitary surgery in patients with RTH. (springer.com)
  • Virtually all the signs and symptoms of Graves' disease result from the direct and indirect effects of hyperthyroidism, with exceptions being Graves' ophthalmopathy, goitre and pretibial myxedema (which are caused by the autoimmune processes of Graves' disease). (wikipedia.org)
  • patients
  • Association between human leukocyte antigen (HLA) and interferon- induced thyroid diseases in four patients with HCV-related chronic hepatitis. (nel.edu)