• transfusion
  • 5 , 6 Early in the new millennium, however, this transfusion paradigm was challenged mainly based on the results from the US Military in Iraq, where thawed AB fresh frozen plasma (FFP) was administered together with RBCs, as well as platelet concentrates (PCs) from the start of resuscitation. (bloodjournal.org)
  • clot
  • 1 - 3 Nevertheless, infusion of a large amount of fluid can cause blood loss and severe hemodilution, induce clot dislocation, and reduce the concentration of platelet and coagulant factors, resulting in deterioration of the resuscitation effect (particularly for uncontrolled hemorrhagic shock). (asahq.org)
  • Issues with fluid resuscitation without control of bleeding is thought to be secondary to dislodgement of the thrombus (blood clot) that is helping to control further bleeding. (wikipedia.org)
  • In addition, fluid resuscitation will dilute coagulation factors that help form and stabilize a clot, hence making it harder for the body to use its natural mechanisms to stop the bleeding. (wikipedia.org)
  • Any higher blood pressure results in the "POP THE CLOT" syndrome and increases the rebleeding, the cyclic hyper resuscitation, blood usage, post op complications and DEATH. (trauma.org)
  • complications
  • The final target for a prehospital or EC measured BP will be that greater than 80 SYSTOLIC will be the level that the QA moral police will cite that those of you who believe in two large bore IVs, Rapid infusors, interosseous and sternal infursors, the 3 to 1 rule, and cyclic hyper resuscitation as causing unnecessary complications, deaths, and costs. (trauma.org)
  • perfusion
  • The typical signs of shock are low blood pressure, rapid heart rate, signs of poor end-organ perfusion (i.e., low urine output, confusion, or loss of consciousness), and weak pulses. (wikipedia.org)
  • patient
  • Keeping the patient hypotensive slows the bleeding, prevents hemodilution, and, strangely enough, does not increase the incidence of ATN. (trauma.org)
  • Despite the administration of broad-spectrum antibiotics, trimethoprim/sulfamethoxazole and voriconazole, and supportive treatment, the patient deteriorated rapidly and developed hypotensive shock associated with a large volume of hematochezia. (bloodresearch.or.kr)
  • tissue
  • Resuscitation is complete when the oxygen debt has been repaid, tissue acidosis eliminated, and normal aerobic metabolism restored in all tissue beds. (east.org)
  • oxygen
  • The depth and duration of shock leads to a cumulative oxygen debt . (east.org)
  • For example, shock may lead to hypoxemia (a lack of oxygen in arterial blood) or cardiac and/or respiratory arrest. (wikipedia.org)
  • abdominal
  • While a fast heart rate is common, those on β-blockers, those who are athletic and in 30% of cases of those with shock due to intra abdominal bleeding may have a normal or slow heart rate. (wikipedia.org)
  • active
  • After resuscitation, angiography detected active bleeding from the superior mesenteric artery, and despite embolizations, a considerable amount of hematochezia still continued, and the toxic megacolon persisted. (bloodresearch.or.kr)