• mechanism
  • Increased microtubule density, for which microtubule stabilization is one potential mechanism, causes contractile dysfunction in cardiac hypertrophy. (rupress.org)
  • Thus, microtubule stabilization, likely facilitated by binding of a microtubule-associated protein, may be a mechanism for the increased microtubule density characteristic of pressure overload cardiac hypertrophy. (rupress.org)
  • seen
  • The radiolucent line, seen in the frontal views, was considered to represent contact of the leading edge of the leaflet with the hypertrophied muscular interventricular septum. (ahajournals.org)
  • Severe hypertrophy was also seen to involve the inferior portion of the muscular septum, causing displacement of the papillary muscles superiorly and to the left. (ahajournals.org)