• belongs
  • Chemically, Perindopril belongs to the class of organic compounds known as peptides that contain an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a peptide bond. (drugsdetails.com)
  • blood pressure
  • Commonly reported adverse events are hypokalemia (low potassium levels), fatigue, orthostatic hypotension (blood pressure decrease on standing up) and allergic manifestations. (wikipedia.org)
  • Under normal conditions, angiotensin II has these effects: Vasoconstriction (narrowing of blood vessels) and vascular smooth muscle hypertrophy (enlargement) induced by AII may lead to increased blood pressure and hypertension. (wikipedia.org)
  • treat
  • The drug is also used to treat hypertension and to reduce the risk of stroke in both hypertensive and nonhypertensive individuals with a history of stroke or transient ischemic attack. (drugsdetails.com)
  • active
  • Following administration, Perindopril is metabolized in vivo by hydrolysis of the ester group to form perindoprilat, the biologically active metabolite. (drugsdetails.com)