Generally, for temporary relief of pain prior to obtaining definitive dental care, the preferred agent is 0.5% bupivacaine (Marcaine, Sensorcaine) with 1:200,000 epinephrine. (medscape.com)
Posimir1
Bupivacaine (Posimir) is indicated in adults for administration into the subacromial space under direct arthroscopic visualization to produce post-surgical analgesia for up to 72 hours following arthroscopic subacromial decompression. (wikipedia.org)
Systemic1
Clinically significant adverse events result from systemic absorption of bupivacaine and primarily involve the central nervous and cardiovascular systems. (wikipedia.org)
Bupivacaine is indicated for local infiltration, peripheral nerve block, sympathetic nerve block, and epidural and caudal blocks. (wikipedia.org)
Infiltration1
Liposomal formulations of bupivacaine (brand name EXPAREL) have not shown clinical benefit compared to plain bupivacaine when used in traditional perineural injections, although some industry-funded studies have suggested benefits when used in local infiltration. (wikipedia.org)
Hypersensitivity to local anesthetic agents: This occurs in less than 1% of the general population. (medscape.com)
Brand2
Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area. (wikipedia.org)
The fixed-dose combination of bupivacaine with Type I collagen (brand name Xaracoll) is indicated for acute postsurgical analgesia (pain relief) for up to 24 hours in adults following open inguinal hernia repair. (wikipedia.org)
Generic1
Bupivacaine is available as a generic medication. (wikipedia.org)
Hydrochloride6
MARCAINE SPINAL (bupivacaine hydrochloride in dextrose injection) is recommended for spinal anesthesia in obstetrical patients. (nih.gov)
The composition of 1 ml of injection solution contains the active substance: bupivacaine hydrochloride - 5 mg. (abchealthonline.com)
Bupivacaine hydrochloride USP is 2-Piperidinecarboxamide, 1-butyl- N -(2,6-dimethylphenyl)-, monohydrochloride, monohydrate, a white, odorless, crystalline powder that is freely soluble in 95 percent ethanol, soluble in water, and slightly soluble in chloroform or acetone. (nih.gov)
Bupivacaine hydrochloride injection, USP is available in sterile isotonic solution for injection via local infiltration, peripheral nerve block, and caudal and lumbar epidural blocks. (nih.gov)
Solution of bupivacaine hydrochloride injection, USP may be autoclaved. (nih.gov)
MARCAINE SPINAL is an amide-local anesthetic indicated in adults for subarachnoid injection for the production of subarachnoid block (spinal anesthesia). (nih.gov)
The dosage of MARCAINE SPINAL administered varies with the anesthetic procedure, the vascularity of the tissues, the number of neuronal segments to be blocked, the depth of anesthesia and degree of muscle relaxation required, the duration of anesthesia desired, individual tolerance, and the physical condition of the patient. (nih.gov)
MARCAINE SPINAL 7.5 mg is generally adequate for spinal anesthesia for lower extremity and perineal procedures. (nih.gov)
There have been reports of cardiac arrest during use of MARCAINE 0.75% solution for epidural anesthesia in obstetrical patients. (nih.gov)
In case of accidental penetration of bupivacaine into the bloodstream, acute systemic toxic reactions may develop, therefore, the drug is not used for intravenous regional anesthesia (Beer blockade). (abchealthonline.com)
The onset of action with bupivacaine is rapid and anesthesia is long lasting. (nih.gov)
Lidocaine5
The amide local anesthetics including lidocaine, bupivacaine and ropivacaine are commonly used for pain control during minor surgery or invasive procedures such as biopsies, small excisions or dental work. (nih.gov)
Lidocaine (lye' do kane), bupivacaine (bue piv' a kane) and ropivacaine (roe piv' a kane) are commonly used local anesthetics that are chemically referred to as aminoethylamides or amide local anesthetics. (nih.gov)
Lidocaine was approved for use as a local anesthetic in the 1948 originally under the commercial name Xylocaine, ropivacaine in 1990 (Naropin), and bupivacaine in 1990 (Marcaine). (nih.gov)
Lidocaine is an amide local anesthetic used in a 0.5-1% concentration in combination with bupivacaine (50:50 mixture). (medscape.com)
Bupivacaine 0.25% may be used in combination with lidocaine plus epinephrine (50:50 mixture). (medscape.com)
Intravascular Injection1
Recent clinical reports and animal research suggest that these cardiovascular changes are more likely to occur after unintended intravascular injection of bupivacaine. (nih.gov)
Bupivacaine is indicated for local infiltration, peripheral nerve block, sympathetic nerve block, and epidural and caudal blocks. (wikipedia.org)
Bupivacaine has caused several deaths when the epidural anaesthetic has been administered intravenously accidentally. (wikipedia.org)
Arthroscopic1
Intra-articular infusions of local anesthetics including bupivacaine following arthroscopic and other surgical procedures is an unapproved use, and there have been post-marketing reports of chondrolysis in patients receiving such infusions. (nih.gov)
Anesthetic1
Known hypersensitivity to bupivacaine or to any local anesthetic agent of the amide-type or to other components of MARCAINE SPINAL. (nih.gov)
Systemic absorption1
Clinically significant adverse events result from systemic absorption of bupivacaine and primarily involve the central nervous and cardiovascular systems. (wikipedia.org)
Amide-type1
Hypersensitivity to the components of the drug, as well as to local anesthetics of the amide type. (abchealthonline.com)
Spinal7
These highlights do not include all the information needed to use MARCAINE ® SPINAL safely and effectively. (nih.gov)
See full prescribing information for MARCAINE ® SPINAL. (nih.gov)
MARCAINE SPINAL 6 mg is generally adequate for vaginal delivery. (nih.gov)
MARCAINE SPINAL 12 mg is generally adequate for lower abdominal procedures. (nih.gov)
Spinal anesthetics, including MARCAINE SPINAL, should not be injected during uterine contractions because cerebrospinal fluid current may carry the drug further cephalad than desired, resulting in a high motor block. (nih.gov)
Monitor cardiovascular and respiratory vital signs and patient's state of consciousness after injection of MARCAINE SPINAL. (nih.gov)
Liposomal2
A liposomal and longer acting preparation of bupivacaine was approved for use in controlling postsurgical pain in 2011 (Exparel). (nih.gov)
Liposomal formulations of bupivacaine (brand name EXPAREL) have not shown clinical benefit compared to plain bupivacaine when used in traditional perineural injections, although some industry-funded studies have suggested benefits when used in local infiltration. (wikipedia.org)
Infusion2
Nevertheless, there have been several case series of jaundice arising a few days to as long as a month after use of bupivacaine given over several days as a constant infusion or as repeated injections into a localized area of pain. (nih.gov)
Additionally, bupivacaine can cause chondrolysis after continuous infusion into a joint space. (wikipedia.org)
Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. (nih.gov)
Clinically1
Likelihood score (bupivacaine): C (probable cause of clinically apparent liver injury). (nih.gov)
Concentration1
A dilute concentration of epinephrine (1:200,000 or 5 mcg/mL) usually reduces the rate of absorption and peak plasma concentration of bupivacaine, permitting the use of moderately larger total doses and sometimes prolonging the duration of action. (nih.gov)
Patients1
Acetaminophen is the drug of choice for the treatment of pain in patients with documented hypersensitivity to aspirin or NSAIDs, as well as in those with upper GI disease or who are taking oral anticoagulants. (medscape.com)
Fixed-dose combin1
The fixed-dose combination of bupivacaine with Type I collagen (brand name Xaracoll) is indicated for acute postsurgical analgesia (pain relief) for up to 24 hours in adults following open inguinal hernia repair. (wikipedia.org)
Block1
Marcaine gives excellent sensory and little motor block. (freezingblue.com)