DiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesHealth Care
Jejunoileal BypassHyperlipidemiasHypercholesterolemiaHyperlipoproteinemia Type IICholesterolAnticholesteremic AgentsReceptors, LDLCholesterol, LDLCholesterol, DietaryHydroxymethylglutaryl-CoA Reductase InhibitorsLipoproteins, LDLXanthomatosisApolipoproteins BEpichlorohydrinAzetidinesArteriosclerosisLipidsDiet, AtherogenicLipoproteinsPrimary PreventionTriglyceridesSimvastatinRisk FactorsApolipoproteins EFibric AcidsHypertriglyceridemiaHypolipidemic AgentsBezafibrateFenofibrateClofibric Acid
CoronaryFamilial hypercholesterolaemiaHypertriglyceridemiaHypertensionHeFHDyslipidemiaObesityLipoproteinDiabetesHoFHType III hyperlipidemiaMedicallyTriglyceridesPrevalence of hypercholesterolemiaAdultsTotal cholesterolPatientsPrevent hypercholesterolemiaLipids in yourAtherosclerotic cardiovascular diseaseFredricksonStrokeTreatmentSlow the progression of atherosclerosisCholesterol levelsStatinsSimvastatinDiagnosisSymptomsSecondary preventionClinicalBloodGeneticReduction
Coronary19
  • Repatha ® is indicated as an adjunct to diet and standard of care therapy (including moderate- to high-intensity statin therapy alone or in combination with other lipid-lowering therapy), to reduce the risk of myocardial infarction, stroke, and coronary revascularization in adult patients with atherosclerotic cardiovascular disease (ASCVD) by further lowering low-density lipoprotein cholesterol (LDL-C) levels. (repatha.ca)
  • Secondary prevention of cardiovascular events in pts with hypercholesterolemia and coronary heart disease (CHD) or at high risk for CHD. (genmed.pk)
  • Individuals with untreated hyperlipidemia are two times as liable to foster coronary course infection (CAD) as those with cholesterol levels in the typical reach. (specialtycareclinics.com)
  • A specialist for the most part recognizes hyperlipidemia during a normal blood test or following a cardiovascular occasion, for example, a coronary episode or stroke. (specialtycareclinics.com)
  • In patients with coronary heart disease (CHD) or at high risk of CHD, ZOCOR can be started simultaneously with diet. (druglib.com)
  • 8 Bennett P, Carroll D. Stress management approaches to the prevention of coronary heart disease. (thieme-connect.de)
  • Prevention of coronary heart disease, cardiovascular and cerebrovascular disease development of total cholesterol prevention, the occurrence of hypercholesterolemia, glycerol three cool, prevent the occurrence of hyperlipidemia. (findtimewatch.com)
  • Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society. (medscape.com)
  • Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. (medscape.com)
  • Familial hypercholesterolemia and coronary heart disease: a HuGE association review. (medscape.com)
  • 20mg to 40mg daily, given as a single dose in the evening in patients at high risk of coronary heart disease with or without hyperlipidaemia. (medscape.co.uk)
  • Diabetic patients often combined with metabolic disorders like hypertension, and hyperlipidemia, easily lead to cardio-cerebrovascular diseases like coronary heart disease, which is a risk factor leading to death [ 2 ]. (biomedcentral.com)
  • The very high-risk patient is one who has multiple major ASCVD [atherosclerotic cardiovascular disease] risk events, something such as an acute coronary syndrome, prior heart attack, peripheral arterial disease, and ischemic stroke. (consultantlive.com)
  • Adults (=18 years),Prevention of Cardiovascular Disease,Ezetimibe and Simvastatin Tablets is indicated in patients with coronary heart disease (CHD) and a history of acute coronary syndrome (ACS) taking their maximum tolerated dose of simvastatin and in need of additional lowering of LDL-C in the expectation of a modest further reduction in the risk of cardiovascular events following at least one year of therapy. (healthdirect.gov.au)
  • Current indications for simvastatin are hypercholesterolemia and reduction in risk for death from coronary, cerebrovascular and peripheral artery disease in patients with these diseases. (nih.gov)
  • Primordial prevention usually refers to healthy lifestyle choices to prevent the development of coronary risk factors. (medscape.com)
  • Primary prevention reduces MI and heart failure, decreases the need for coronary revascularization procedures, and extends and improves the quality of life. (medscape.com)
  • Overall and for the subset of people aged 50 years or older, diabetes, hypertension, hypercholesterolemia, coronary heart disease, and stroke were significantly more prevalent among male veterans with MS than among the general population. (cdc.gov)
  • Page 2 of 10 epidemiologic data on chronic disease prevalence in men with MS. Our objective was to identify chronic diseases that may disproportionately affect male veterans with MS. Diabetes, hypertension, hypercholesterolemia, coronary heart disease (CHD), and stroke were assessed because they are associated with the leading causes of illness and death in the United States (5). (cdc.gov)
Familial hypercholesterolaemia8
  • Hypercholesterolaemia Atorvastatin Miklich is indicated as an adjunct to diet for reduction of elevated total cholesterol (total-C), LDL-cholesterol (LDL-C), apolipoprotein B, and triglycerides in adults, adolescents and children aged 10 years or older with primary hypercholesterolaemia including familial hypercholesterolaemia (heterozygous variant) or combined (mixed) hyperlipidaemia (Corresponding to Types IIa and IIb of the Fredrickson classification) when response to diet and other nonpharmacological measures is inadequate. (ravimiregister.ee)
  • A review on the diagnosis, natural history, and treatment of familial hypercholesterolaemia. (medscape.com)
  • Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment. (medscape.com)
  • Adjunctive treatment of homozygous familial hypercholesterolaemia with diet and other lipid lowering treatments (e.g. (medscape.co.uk)
  • Primary Hypercholesterolaemia,Ezetimibe and Simvastatin Tablets is indicated as adjunctive therapy to diet in patients with primary (heterozygous familial and non-familial) hypercholesterolaemia or mixed hyperlipidaemia where use of a combination product is appropriate:, Patients not appropriately controlled with a statin or ezetimibe alone. (healthdirect.gov.au)
  • Homozygous Familial Hypercholesterolaemia (HoFH),Ezetimibe and Simvastatin Tablets is indicated in patients with HoFH. (healthdirect.gov.au)
  • Children and Adolescents 10-17 years,(pubertal status: boys Tanner Stage II and above and girls who are at least one year post-menarche),Heterozygous Familial Hypercholesterolaemia (HeFH),Ezetimibe and Simvastatin Tablets is indicated as adjunctive therapy to diet in adolescent patients (10-17 years old) with heterozygous familial hypercholesterolaemia where use of a combination product is appropriate:, Patients not appropriately controlled with a statin or ezetimibe alone. (healthdirect.gov.au)
  • Homozygous Familial Hypercholesterolaemia (HoFH),Ezetimibe and Simvastatin Tablets is indicated in adolescent patients (10-17 years old) with HoFH. (healthdirect.gov.au)
Hypertriglyceridemia4
Hypertension5
  • Metabolic syndrome is defined as a cluster of metabolic abnormalities including obesity, hyperlipidemia, hyperglycemia, insulin resistance, and hypertension [ 3 ]. (hindawi.com)
  • Obesity remains strongly associated with diabetes, hypercholesterolemia, and hypertension in the KSA, although the epidemic's characteristics differ between men and women. (cdc.gov)
  • Or if you have one of those along with some other high-risk features, like age over 65, diabetes, hyperlipidemia, hypertension, chronic kidney disease, you're a current smoker, or persistently elevated LDL or triglycerides, or history of heart failure. (consultantlive.com)
  • In the United States, approximately 78 million people - or 1 in 3 adults - have hypertension, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher (1). (cdc.gov)
  • Hypertension and hyperlipidemia are more common among workers exposed to loud noise in the workplace, suggests new research from the National Institute for Occupational Safety and Health (NIOSH), part of the Centers for Disease Control and Prevention (CDC). (medscape.com)
HeFH1
Dyslipidemia2
  • 2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult - 2009 recommendations. (guiasalud.es)
  • Reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and triglycerides (TG), and to increase high-density lipoprotein cholesterol (HDL-C) in patients with primary hyperlipidemia (Fredrickson type IIa, heterozygous familial and nonfamilial) or mixed dyslipidemia (Fredrickson type IIb). (druglib.com)
Obesity8
  • Hyperlipidemia, characterized by the abnormal blood lipid profiles, is one of the dominant factors of many chronic diseases such as diabetes, obesity, and cardiovascular diseases (CVD). (hindawi.com)
  • Apart from CVD, hyperlipidemia is also closely associated with diabetes, insulin resistance, and obesity [ 10 ]. (hindawi.com)
  • Previous studies have reported the therapeutic properties of A. iwayomogi on obesity, hyperlipidemia, and liver fibrosis [ 7 , 8 ]. (hindawi.com)
  • Therefore, we evaluated the effect of ACE on major manifestations of metabolic syndrome including obesity, hyperlipidemia, and fatty liver using a high-fat diet mouse model. (hindawi.com)
  • 10 Kaneko M, Oda N, Wada N, Okazaki I. The study of the relation between the working conditions and the prevalences of obesity, liver disorder and hyperlipidemia: Evaluation of physiological examination data during the terms of car manufacturing work and car sales work. (thieme-connect.de)
  • The recognition of the role of elevated body mass index (BMI) in these changes has made obesity a high priority for health authorities around the world (6). (cdc.gov)
  • Women, the poor, and older people are at higher risk of obesity worldwide (8,9). (cdc.gov)
  • Data from the late 1980s through mid-1990s show a prevalence of obesity averaging about 20%, ranging from as low as 13.1% among men to as high as 26.6% among women. (cdc.gov)
Lipoprotein10
  • With hypercholesterolemia, you either have too much LDL cholesterol or too little high-density lipoprotein (HDL) cholesterol in your blood. (healthline.com)
  • High-density lipoprotein (HDL) cholesterol is also known as "good" cholesterol. (healthline.com)
  • Homozygous familial hypercholesterolemia (HoFH) is a rare form of familial hypercholesterolemia, an autosomal-dominant genetic disorder of lipid metabolism characterized by strikingly elevated levels of low-density lipoprotein cholesterol (LDL-C). (delveinsight.com)
  • 2 This guideline's unique approach was to shift away from the practice of treating lipid targets to specific goals (i.e., for low-density lipoprotein cholesterol [LDL-C] and non-high-density lipoprotein cholesterol [non-HDL-C]). Instead, the guideline recommended moderate- to high-intensity statin therapy for four groups of patients most likely to achieve maximal net benefit based on their increased risk. (aafp.org)
  • Hyperlipidemia is an elevation of total cholesterol (TC) or non-high-density-lipoprotein (HDL) cholesterol (TC minus HDL-cholesterol). (contemporaryclinic.com)
  • Pravastatin is also used to reduce the amount of fatty substances such as low-density lipoprotein (LDL) cholesterol ('bad cholesterol') and triglycerides in the blood and to increase the amount of high-density lipoprotein (HDL) cholesterol ('good cholesterol') in the blood. (safemedication.com)
  • A rare inherited genetic disorder, one form of HYPERLIPOPROTEINEMIA TYPE II, characterized by high level of LOW-DENSITY LIPOPROTEIN (LDL) which if not treated could elevate the chance of heart attack at an early age. (bvsalud.org)
  • Although high-density lipoprotein-cholesterol (HDL-C) showed a flat pattern for all ages in both genders, its level in women was higher than in men. (thieme-connect.de)
  • it also raises high density lipoprotein cholesterol and lowers the LDL/HDL and total cholesterol/HDL ratios. (drugstocker.com)
  • The risk-enhancing factors include premature atherosclerotic disease in the family, primary hypercholesterolemia that doesn't quite meet that 190 mg/dL LDL [low-density lipoprotein] threshold, metabolic syndrome or that conglomeration of factors that was just mentioned, chronic kidney disease, chronic inflammatory conditions such as lupus, rheumatoid arthritis, HIV. (consultantlive.com)
Diabetes15
  • Prevention of CV events in type 2 diabetes: Did not reduce primary composite outcome (nonfatal MI or CV death). (medscape.com)
  • The 1982 publication of The Prevention and Treatment of Five Complications of Diabetes: A Guide for Primary Care Practitioners was an initial attempt to provide straightforward and practical information that primary care practitioners could immediately apply in their practice in the diagnosis and prevention of complications of diabetes. (cdc.gov)
  • The recommendations relate to the prevention, detection, and treatment of the major complications of diabetes. (cdc.gov)
  • Young people with insulin- dependent diabetes mellitus (IDDM) may have a higher prevalence of eating disorders, such as anorexia nervosa and bulimia, and adults with longstanding diabetes and major medical complications have a higher prevalence of symptoms of depression and anxiety. (cdc.gov)
  • Elderly persons who have non-insulin-dependent diabetes mellitus (NIDDM) and other symptomatic medical conditions may also have a higher risk of developing psychological problems. (cdc.gov)
  • This study was to explore the effect of hyperlipidemia on the incidence of cardio-cerebrovascular diseases in patients with type 2 diabetes. (biomedcentral.com)
  • The incidence of cardio-cerebrovascular diseases between diabetes combined with hyperlipidemia group (195 patients) and diabetes group (200 patients) were made a comparison. (biomedcentral.com)
  • Multivariable Cox's proportional hazards regression model was used to analyze the effect of hyperlipidemia on the incidence of cardio-cerebrovascular diseases in patients with type 2 diabetes. (biomedcentral.com)
  • The analysis results of multivariable Cox's proportional hazards regression model showed that the risks of myocardial infarction and total cardiovascular events in diabetes combined with hyperlipidemia group were respectively 1.54 times (95% CI 1.13-2.07) and 1.68 times (95% CI 1.23-2.24) higher than those in diabetes group. (biomedcentral.com)
  • Population attributable risk percent of all-cause mortality and total cardiovascular events in patients with type 2 diabetes combined with hyperlipidemia was 9.6% and 26.8%, respectively. (biomedcentral.com)
  • Hyperlipidemia may promote vascular endothelial injury, increasing the risk of cardio-cerebrovascular diseases in patients with type 2 diabetes. (biomedcentral.com)
  • In high-income countries, type 2 diabetes accounted for 85%~ 95% of diabetes, which might be higher in middle-income and low-income countries. (biomedcentral.com)
  • Three hundred ninety five patients with type 2 diabetes in our hospital from January 2012 to January 2016 were divided into diabetes combined with hyperlipidemia group (195 patients) and diabetes group (200 patients). (biomedcentral.com)
  • Less than 50% of high-risk primary prevention patients are being treated, and remarkably, only a little more than half of patients with diabetes are getting the appropriate LDL-lowering therapy, typically statins. (medscape.com)
  • Identification of individuals at high-risk for pancreatic cancer using a digital patient-input tool combining family cancer history screening and new-onset diabetes. (cdc.gov)
HoFH3
Type III hyperlipidemia1
  • Reduce elevated TG and VLDL-C in patients with primary dysbetalipoproteinemia (Fredrickson type III hyperlipidemia). (druglib.com)
Medically1
Triglycerides9
Prevalence of hypercholesterolemia1
Adults8
  • Unfortunately, hypercholesterolemia is a common issue among U.S. adults. (healthline.com)
  • Females, older adults, and Chinese people may be at higher risk. (bidrx.com)
  • 10) National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). (guiasalud.es)
  • Two PCSK9 inhibitors (evolocumab [Repatha] and ali-rocumab [Praluent]) are approved by the U.S. Food and Drug Administration (FDA) for use in addition to diet and maximally tolerated statin therapy in adults with heterozygous familial hypercholesterolemia or clinical ASCVD who require additional reductions in LDL-C. 15 , 16 Evolocumab is also approved to treat patients with homozygous familial hypercholesterolemia. (aafp.org)
  • The recognition and management of hyperlipidemia in adults: A policy statement of the European Atherosclerosis Society. (thieme-connect.de)
  • Guideline for Diagnosis and Treatment of Hyperlipidemias in Adults. (thieme-connect.de)
  • Nonalcoholic fatty liver disease (NAFLD) is a globally observed metabolic disease with high prevalence both in adults and children. (mdpi.com)
  • A study by Pande et al suggests millions of US adults with peripheral arterial disease (PAD) are not receiving secondary prevention therapies. (medscape.com)
Total cholesterol2
Patients28
  • Phase 3, 12-week, randomized, double-blind, placebo- and ezetimibe-controlled trial (N=1,896) in patients with primary hyperlipidemia (including 526 who had ASCVD) on maximum dose statin therapy. (repatha.ca)
  • These high LDL levels, if untreated, can cause aggressive narrowing and blocking of the blood vessels even before birth, which progresses rapidly, triggering serious cardiac issues for patients much earlier in life than the general population. (delveinsight.com)
  • The retail health clinic setting provides a unique opportunity to identify patients with hyperlipidemia and related cardiovascular risk factors. (contemporaryclinic.com)
  • Because the benefits of statins may include prevention of serious or potentially fatal events in a small group of very high-risk pregnant patients, contraindicating these drugs in all pregnant women is not appropriate. (safemedication.com)
  • FDA expects removing the contraindication will enable health care professionals and patients to make individual decisions about benefit and risk, especially for those at very high risk of heart attack or stroke. (safemedication.com)
  • This includes patients with homozygous familial hypercholesterolemia and those who have previously had a heart attack or stroke. (safemedication.com)
  • Patients who are at high risk of heart attack or stroke who require statins after giving birth should not breastfeed and should use alternatives such as infant formula. (safemedication.com)
  • Health Care Professionals: Health care professionals should discontinue statin therapy in most pregnant patients, or they can consider the ongoing therapeutic needs of the individual patient, particularly those at very high risk for cardiovascular events during pregnancy. (safemedication.com)
  • Reduce total-C and LDL-C in patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments (e.g. (druglib.com)
  • Prevention of cardiovascular disease Prevention of cardiovascular events in adult patients estimated to have a high risk for a first cardiovascular event (see section 5.1), as an adjunct to correction of other risk factors. (ravimiregister.ee)
  • Reduction of cardiovascular mortality and morbidity in addition to diet in patients with moderate or severe hypercholesterolaemia and a high risk of a first cardiovascular event. (gl-pharma.com)
  • Reduction of post-transplant hyperlipidaemia in patients receiving immunosuppressive therapy after organ transplantation. (gl-pharma.com)
  • This dose is only recommended in patients with severe hypercholesterolaemia and high risk for cardiovascular complication who have not achieved their treatment goals on lower doses and when benefits are expected to outweigh the potential risks. (medscape.co.uk)
  • A dose of 5mg daily in combination with non-pharmacological measures (e.g. exercise, diet and weight reduction) may be suitable for patients with less severe hypercholesterolaemia. (medscape.co.uk)
  • An epidemiological survey showed the incidence of acute stroke in patients with high hyper-sensitive C-reactive protein (hs-CRP) level was two times higher than healthy people and myocardial infarction was three times higher [ 9 ]. (biomedcentral.com)
  • Abstract Background Most studies focused on the benefits of lycopene on serum lipids but no studies have been specifically designed to assess the role of a tomato sauce from vine-ripened tomatoes on patients affected by polygenic hypercholesterolemia. (researchgate.net)
  • Methods In this cross-over study, we evaluated a population of 108 ambulatory patients affected by polygenic hypercholesterolemia of both gender, who were allocated to a tomato sauce (namely OsteoCol) 150 ml/day or a sterol-enriched yogurt (containing sterols 1.6 g/die) treatment, for 6 weeks. (researchgate.net)
  • carotenoid content may support treatment of patients affected by common hypercholesterolemia. (researchgate.net)
  • In our primary prevention cohort, we know there are different groups of patients who are at higher risk that we can't quite put our finger on. (consultantlive.com)
  • But the intensity of LDL lowering depends on the recommendations based on the absolute risk of the patient, for higher risk patients we recommend even more intensive LDL lowering. (consultantlive.com)
  • Also, as you mentioned in secondary prevention, there are tiers of secondary prevention with certain patients being at very high risk who need the most aggressive LDL lowering. (consultantlive.com)
  • ALT elevations are clearly more frequent in patients taking higher doses of simvastatin (40 and 80 mg daily). (nih.gov)
  • Data on health-related quality of life accrued from digitally engaged patients identified improvements among patients reporting high adherence to study treatment, but patient numbers were small. (jmir.org)
  • First, we were eager to do this study because, as I think most people know, there are a certain number of patients that get adverse effects, typically myalgias, from statins , and they're very difficult patients to treat and many of them are very high risk. (medscape.com)
  • The procedures that we do are very expensive, but the elegance and art of medicine are really in identifying those patients that are under that umbrella of high-risk primary prevention and coming up with evidence-based strategies for them. (medscape.com)
  • We took a chance and we enrolled 30% primary prevention patients. (medscape.com)
  • What happened was the primary prevention patients had a much larger treatment effect than the secondary prevention patients. (medscape.com)
  • A summary of available imaging tests for low-, intermediate-, and high-risk asymptomatic patients is outlined in this document. (bvsalud.org)
Prevent hypercholesterolemia2
Lipids in your1
  • Hyperlipidemia (also known as "lipid disorder") refers to high lipids in your blood. (healthline.com)
Atherosclerotic cardiovascular disease2
  • This issue of American Family Physician includes a review of patient-centered evidence supporting the use of lipid-lowering therapy for the prevention of atherosclerotic cardiovascular disease (ASCVD). (aafp.org)
  • Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of mortality in the United States despite a strong emphasis on prevention, accounting for more than 800,000 deaths in 2017. (jabfm.org)
Fredrickson1
  • ZOCOR has not been studied in conditions where the major abnormality is elevation of chylomicrons (i.e., hyperlipidemia Fredrickson types I and V). (druglib.com)
Stroke4
  • A level of 40 mg/dL or lower (for males) and 50 mg/dL or lower (for females) is considered to put you at a higher risk of a heart attack and stroke . (healthline.com)
  • People with high cholesterol levels are more prone to heart-related issues like heart attack and stroke . (healthline.com)
  • However, when you have too much of this fatty substance, its considered hyperlipidemia, hypercholesterolemia or high blood cholesterola major risk factor for heart attack, heart disease and stroke. (healthycholesterolclub.com)
  • Suvast is used to prevent different heart diseases such as stroke, heart attack and other conditions that is caused by high blood cholesterol. (drugstocker.com)
Treatment13
  • The first choice of treatment for hypercholesterolemia is usually lifestyle modification. (healthline.com)
  • Your doctor may recommend a plan of treatment for high cholesterol that includes lifestyle modifications and potentially medication. (healthycholesterolclub.com)
  • Treatment of heterozygous familial hypercholesterolemia in adolescents (10?17 yrs females more than 1 yr postmenarche). (genmed.pk)
  • [ 6 ] The role of hyperlipidemia and statin treatment in the prevention of aortic stenosis is unclear, although hypercholesterolemia is an often cited risk factor. (medscape.com)
  • Thus, prevention and treatment of hyperlipidemia are effective approaches to reduce the incident rate of chronic diseases. (hindawi.com)
  • There is a growing interest in TCM treatment of hyperlipidemia. (hindawi.com)
  • In the last few decades, hundreds of Chinese herbal medicines in the form of compounds, extracts, single herbs, or formulae have been reported to be effective for the prevention and treatment of hyperlipidemia [ 16 ], especially those high-fat diet (HFD) induced cases. (hindawi.com)
  • Because of the chronic nature of cardiovascular disease, treatment of hyperlipidemia is not generally necessary during pregnancy. (safemedication.com)
  • The purpose of this study is to examine the rates of statin use for secondary prevention of ASCVD events in the United States over the last decade and determine whether disparities in the treatment of ASCVD still persist among women and racial/ethnic minorities. (jabfm.org)
  • 3 Investigating Committee of Guideline for Diagnosis and Treatment of Hyperlipidemias, Japan Atherosclerosis Society. (thieme-connect.de)
  • Dietary treatment of familial hypercholesterolemia. (medscape.com)
  • Treatment of primary hypercholesterolaemia or mixed dyslipidaemia, in addition to diet, when response to diet and other non-pharmacological measures (e.g. exercise, weight loss) is inadequate. (gl-pharma.com)
  • Adjunctive treatment of primary hypercholesterolaemia or mixed dyslipidaemia with dietary measures when response to diet and other non-pharmacological treatments (e.g. exercise and weight reduction) is inadequate. (medscape.co.uk)
Slow the progression of atherosclerosis2
Cholesterol levels6
Statins6
  • Statins are the most commonly prescribed medications for hypercholesterolemia. (healthline.com)
  • Rosuvastatin is a member of the drug class of statins, used in combination with exercise, diet, and weight-loss to treat high cholesterol and related conditions and to prevent cardiovascular disease. (illnesshacker.com)
  • We conducted a trend analysis using data from 2008 through 2016 to describe age-adjusted trends in the use of statins for secondary prevention using the Medical Expenditure Panel Survey. (jabfm.org)
  • Our study found there was no increase in the national rates of statin use following the ACC/AHA 2013 secondary prevention guideline and the availability of generic statins. (jabfm.org)
  • An important addition to the guidelines is the emphasis on risk-enhancing factors if present, put someone into a higher cardiovascular risk category they might be considering about statins and primary prevention. (consultantlive.com)
  • They all had to have documented statin intolerance and they had to, in writing, state that they understood that statins were established for cardiovascular prevention, but that they would not and could not take a statin. (medscape.com)
Simvastatin1
  • High-dose simvastatin for aneurysmal subarachnoid hemorrhage: multicenter randomized controlled double-blinded clinical trial. (druglib.com)
Diagnosis1
  • Familial hypercholesterolemia: a challenge of diagnosis and therapy. (medscape.com)
Symptoms5
Secondary prevention9
  • Cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease CG67. (guiasalud.es)
  • 2 Such goals must be defined, because indiscriminate use of expensive monoclonal antibodies (i.e., the current cost of therapy is approximately $14,000 per year) for primary and secondary prevention of ASCVD will have a deep impact on health care costs. (aafp.org)
  • When assessing any patient when we first look at them, we think of primary prevention or secondary prevention. (consultantlive.com)
  • Then in our secondary prevention cohort, we need to think about that very high-risk patient, or that just plain old high-risk patient. (consultantlive.com)
  • Secondary prevention relies on early detection of disease process and application of interventions to prevent progression of disease (MeSH definition). (medscape.com)
  • This article summarizes the guidelines for the primary and secondary prevention of CHD. (medscape.com)
  • We focus so much on secondary prevention , and to me, when we get to secondary prevention, it represents a failure on our part. (medscape.com)
  • We focus all our resources on secondary prevention. (medscape.com)
  • In CLEAR Outcomes, we wanted to have evidence for both primary and secondary prevention. (medscape.com)
Clinical3
  • Risk estimation and the prevention of cardiovascular disease: a national clinical guideline. (guiasalud.es)
  • Dr. Cho's clinical research interests are women and heart disease and the role of new treatments for hyperlipidemia and novel risk factor. (clevelandclinic.org)
  • High-Grade Serous Carcinoma at Risk-Reducing Salpingo-Oophorectomy in Asymptomatic Carriers of BRCA1/2 Pathogenic Variants: Prevalence and Clinical Factors. (cdc.gov)
Blood13
  • Hyperlipidemia is a condition where you have a high level of lipids (fats) in your blood. (healthline.com)
  • Because HDL cholesterol plays an important role in getting rid of LDL, you want higher levels of HDL in your blood. (healthline.com)
  • Various inherited or acquired disorders that cause high lipid levels in the blood fall under this umbrella category. (healthline.com)
  • If you have these mutations, your blood LDL cholesterol can reach dangerously high levels. (healthline.com)
  • A high level of cholesterol indicates you have too many fats in your blood. (specialtycareclinics.com)
  • Conversely, Curcuma longa ( C. longa ) has been used to treat the pathological condition of blood stasis and reportedly exerts a beneficial effect on hyperlipidemia [ 9 , 10 ]. (hindawi.com)
  • High cholesterol is significant risk factor for cardiovascular disease, along with high blood pressure and smoking. (contemporaryclinic.com)
  • Long-term mental work or high-intensity exercise may lead to a decrease in blood oxygen, causing discomfort. (findtimewatch.com)
  • Using high-performance optical sensors and self-developed optimization algorithms, accurately measure and record your blood pressure. (findtimewatch.com)
  • Thus, prevention of elevated blood pressure can avert many CVD-related deaths. (cdc.gov)
  • Reducing workplace noise levels is critical not just for hearing loss prevention - it may also impact blood pressure and cholesterol," NIOSH Director John Howard, MD, said in a news release. (medscape.com)
  • Worksite health and wellness programs that include screenings for high blood pressure and cholesterol should also target noise-exposed workers. (medscape.com)
  • For anyone in an environment with increased noise levels, it's not just hearing loss that we have to think about, but there may in fact be some risk for high blood pressure and high cholesterol. (medscape.com)
Genetic3
Reduction2