• Abnormal
  • The International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) is a coding of diseases and signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or diseases, as classified by the World Health Organization (WHO). (wikipedia.org)
  • primary
  • The recommended dose of evolocumab to treat primary hyperlipidemia is 140 mg injected subcutaneously (under the skin) every 2 weeks or 420 mg injected subcutaneously once a month. (medbroadcast.com)
  • statin
  • Since individuals with FH underlying body biochemistry is slightly different, their high cholesterol levels are less responsive to the kinds of cholesterol control methods which are usually more effective in people without FH (such as dietary modification and statin tablets). (wikipedia.org)
  • Nevertheless, treatment (including higher statin doses) is usually effective. (wikipedia.org)
  • stroke
  • Over time, these plaques can block the arteries and cause heart disease, stroke, and other symptoms or problems throughout the body. (medlineplus.gov)
  • Mitral stenosis poses a high risk of forming emboli which may travel to the brain and cause stroke. (wikipedia.org)
  • The results of the JUPITER trial (2008) suggested rosuvastatin may decrease the relative risk of heart attack and stroke in patients without hyperlipidemia, but with elevated levels of highly sensitive C-reactive protein. (wikipedia.org)
  • Severe
  • Play media The most common symptoms of pancreatitis are severe upper abdominal or left upper quadrant burning pain radiating to the back, nausea, and vomiting that is worse with eating. (wikipedia.org)
  • atorvastatin
  • Geriatric: Plasma concentrations of atorvastatin in healthy elderly subjects are higher than those in young adults, and clinical data suggests a greater degree of LDL-lowering at any dose for patients in the population as compared to young adults. (wikipedia.org)
  • risk
  • Advise patient to drink plenty of fluids and maintain a high fiber intake to minimize risk of constipation. (drugs.com)
  • The Internal Carotid Artery is also at high risk to be affected. (wikipedia.org)
  • Very high levels that would increase the risk of pancreatitis is treated with a drug from the fibrate class. (wikipedia.org)
  • Other efforts include managing high blood pressure, high blood cholesterol, and infection risk. (wikipedia.org)
  • In 1982, some small-scale clinical investigations of lovastatin, a polyketide-derived natural product isolated from Aspergillus terreus, in very high-risk patients were undertaken, in which dramatic reductions in LDL cholesterol were observed, with very few adverse effects. (wikipedia.org)
  • include
  • Symptoms of embolisation in an organ vary with the organ involved but commonly include: Pain in the involved body part Temporarily decreased organ function Later symptoms are closely related to infarction of the affected tissue. (wikipedia.org)
  • Symptoms of limb infarction include coldness, decreased or no pulse beyond the site of blockage, pain, muscle spasm, numbness and tingling, pallor and muscle weakness, possibly to the grade of paralysis in the affected limb. (wikipedia.org)
  • Other symptoms may include weight gain, feeling tired, and foamy urine. (wikipedia.org)
  • Complications may include blood clots, infections, and high blood pressure. (wikipedia.org)
  • liver
  • Hyperlipidaemia is caused by two factors: Hypoproteinemia stimulates protein synthesis in the liver, resulting in the overproduction of lipoproteins. (wikipedia.org)
  • Results
  • Early-stage preclinical studies suggested that bexarotene reduced amyloid plaques and improved mental functioning in a small sample of mice engineered to exhibit Alzheimer's-like symptoms although subsequent studies have yielded mixed results. (wikipedia.org)
  • closely related
  • Lovastatin is also naturally produced by certain higher fungi, such as Pleurotus ostreatus (oyster mushroom) and closely related Pleurotus spp. (wikipedia.org)