Atropa baetica, commonly known as the Andalusian belladonna, is one of Europe's rarest wildflowers. (wikipedia.org)
A close relative of the infamous deadly nightshade (Atropa belladonna), its specific name derives from that of the Roman province of Hispania Baetica, while its common name refers to the Spanish region of Andalucía - both designating the area in the south of Spain where it is most frequently encountered. (wikipedia.org)
The leaves of belladonna contain 0.3-0.75% of the amount of alkaloids (mainly hyoscyamine), in the roots - a little more. (medprep.info)
Hyoscyamine Sulfate is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity. (lktlabs.com)
Atropa belladonna is a highly poisonous plant which contains variety of active alkaloids such as atropine, scopolamine and many others. (ijpsonline.com)
It is prepared from plant Atropa belladonna, commonly known as 'deadly nightshade' known to be most poisonous plant in world[ 3 ]. (ijpsonline.com)
Atropa belladonna is a medicinal plant and main commercial source of tropane alkaloids (TAs) including scopolamine and hyoscyamine, which are anticholine drugs widely used clinically. (bvsalud.org)
Although the antiviral properties of Atropa belladonna and some of its active components, such as atropine and scopolamine, have been studied, the effect of another important component, hyoscyamine, against JEV infection has not yet been investigated. (bvsalud.org)
Atropine, a naturally occurring belladonna alkaloid, is a racemic mixture of equal parts of d- and l-hyoscyamine, whose activity is due almost entirely to the levo isomer of the drug. (sdrugs.com)
It is a secondary metabolite found in certain plants of the Solanaceae family, including henbane ( Hyoscyamus niger ), mandrake ( Mandragora officinarum ), jimsonweed ( Datura stramonium ), tomato ( Solanum lycopersicum ) and deadly nightshade ( Atropa belladonna ). (curecrowd.com)
The term "tropane" is derived from just one genus in the family Solanaceae - Atropa (the belladonna genus), named after the Greek Fate, Atropos, who cut the thread of life. (allaboutheaven.org)
Only the 1: 1 mixture of ( R ) - and ( S ) -hyoscyamine is called atropine (see Cahn-Ingold-Prelog convention for naming). (zxc.wiki)
In herbal medicine the leaves of this plant that contains numerous alkaloids with anticholinergic and antimuscarinic properties are used: l-hyoscyamine and atropine, scopolamine or hyoscine and, all of them potentially high toxic. (e-lactancia.org)
While the leaf, blossom and rhizome have a resemblance with Atropa, the fruits of scopolia are akin to that of Hyoscyamus. (herbs2000.com)
Hyoscine1
Hyoscyamine should not be confused with hyoscine, an older alternate name for the related nightshade-derived anticholinergic scopolamine . (curecrowd.com)
Scopolamine and hyoscyamine1
Rich in alkaloids such as scopolamine and hyoscyamine, if ingested by humans, the trumpets can cause diarrhoea, confusion, migraines, paralysis and even death. (australiangeographic.com.au)
Anticholinergic3
Like the other three (generally accepted) species of Atropa, it is an extremely poisonous plant, containing a variety of tropane alkaloids with anticholinergic, deliriant, antispasmodic and mydriatic properties. (wikipedia.org)
Myers J, Moro-Sutherland D, Shook J. Anticholinergic poisoning in colicky infants treated with hyoscyamine sulfate. (lktlabs.com)
Tropane alkaloids (TA) including anisodamine, anisodine, hyoscyamine and scopolamine are a group of important anticholinergic drugs with rapidly increasing market demand, so it is significant to improve TA production by biotechnological approaches. (biomedcentral.com)
Baetica3
The Rif and the Baetic System, which face each other across the Alboran Sea (which includes the Strait of Gibraltar), together constitute one of the finest of the Mediterranean biodiversity hotspots - rich in endemic species, of which Atropa baetica is a notable example. (wikipedia.org)
Chromosome number of Atropa baetica and infraspecific taxa 2n=72 Atropa baetica is a calcicole species with a distribution centred upon the limestone mountains of the South and Southeast of the Iberian Peninsula and Northwest Africa. (wikipedia.org)
Although native in the Serrania de Cuenca, Atropa baetica has also been aided in the distribution of its seed there by human activity: in 1936, local gatherers of medicinal plants gathered ripe berries from plants in the area and sowed the seed in various localities in the Serrania in an attempt to replace the plants that they were harvesting and thus ensure the feasibility of future harvests of mature plants. (wikipedia.org)
Species1
Another species, Atropa acuminata Roy, grows in India and is used in England. (medprep.info)
Muscarinic receptors1
Hyoscyamine functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as well as the eye, heart, bladder, and gastrointestinal tract. (lktlabs.com)
Found1
Hyoscyamine sulphate was also found to cause significant downregulation of TLR4. (bvsalud.org)
Activity1
In this study, we investigated the antiviral effect of hyoscyamine against JEV and its immunomodulatory activity in embryonated chicken eggs. (bvsalud.org)
Important1
When hyoscyamine is used along with opioids or other anti-peristaltic agents, measures to prevent constipation are especially important given the risk of paralytic ileus . (curecrowd.com)
Significant1
Pretreatment with hyoscyamine sulphate resulted in a significant decrease in the viral load in both chorioallantoic membrane (CAM) and brain tissues at 48 and 96 hours postinfection. (bvsalud.org)
Alkaloids2
Like the other three (generally accepted) species of Atropa, it is an extremely poisonous plant, containing a variety of tropane alkaloids with anticholinergic, deliriant, antispasmodic and mydriatic properties. (wikipedia.org)
Enhanced secretion of tropane alkaloids in Nicotiana tabacum hairy roots expressing heterologous hyoscyamine-6beta-hydroxylase. (ncats.io)
Sulfate1
Because of its anticholinergic properties, hyoscyamine sulfate drops are often prescribed for the treatment of colic in infants. (nih.gov)
Anticholinergic3
However, five cases are reported of infants with anticholinergic toxicity following the administration of hyoscyamine drops for the treatment of colic. (nih.gov)
These cases emphasize the need for a heightened awareness by emergency physicians and pediatricians of possible anticholinergic toxicity caused by the use of hyoscyamine for infant colic. (nih.gov)
Hyoscyamine as a natural plant alkaloid derivative and anticholinergic. (ncats.io)
Although native in the Serrania de Cuenca, Atropa baetica has also been aided in the distribution of its seed there by human activity: in 1936, local gatherers of medicinal plants gathered ripe berries from plants in the area and sowed the seed in various localities in the Serrania in an attempt to replace the plants that they were harvesting and thus ensure the feasibility of future harvests of mature plants. (wikipedia.org)
Variety1
Hyoscyamine is used to treat a variety of stomach/intestinal problems such as cramps and irritable bowel syndrome. (ncats.io)