FetalisAscitesFetusesFetusDopplerEdemaNonimmunePrenatal diagnosisAnomaliesEchocardiographyUmbilicalUltrasoundAbnormalitiesAnemiaAmniocentesisPlacentaCharacterized by maternalGestationalChromosomalObstetricianTransfusionsMaternal circulationNeonatalHematocritPregnancyBiophysicalAntibodiesFluidDestructionHeartMethodsBlood cellsRisk
Fetalis14
- Hydrops fetalis is a serious fetal condition defined as abnormal accumulation of fluid in 2 or more fetal compartments, including ascites , pleural effusion , pericardial effusion , and skin edema. (medscape.com)
- Immune-related hydrops fetalis (IHF) results from alloimmune hemolytic disease or Rh isoimmunization and before routine immunization of Rh-negative mothers, with most cases being caused by erythroblastosis from Rh alloimmunization. (medscape.com)
- The rise in illicit intravenous (IV) opioid use during pregnancy has been reported to lead to isoimmune hemolysis in the fetus, which results in fetal death or severe hydrops fetalis. (medscape.com)
- Nonimmune-related hydrops fetalis (NIHF) now accounts for almost 90% of cases of hydrops. (medscape.com)
- Hydrops fetalis is often diagnosed with routine sonograms in which the typical features are depicted. (medscape.com)
- In other fetuses, a clinical suspicion of hydrops fetalis may exist because of a previous family history of a similarly affected baby or because ultrasonography is performed to evaluate polyhydramnios. (medscape.com)
- Blood tests performed in the mother can provide information regarding Rh and other immune causes of hydrops fetalis, as well as evidence of infection and metabolic diseases. (medscape.com)
- This study reviewed and analyzed the prenatal diagnosis experience of thalassemia in our center over the past decade and the abnormal ultrasonic characteristics of fetuses with hemoglobin (Hb) Bart's hydrops fetalis. (nih.gov)
- RESULTS: Invasive prenatal α-thalassemia diagnosis and ultrasonography were performed in 1049 patients at risk for Hb Bart's hydrops fetalis syndrome at our hospital from 2012 to 2021. (bvsalud.org)
- Hb Bart's hydrops fetalis syndrome was diagnosed in 280 fetuses. (bvsalud.org)
- CONCLUSIONS: The extensive experience at our center shows that carrier screening, molecular diagnostics, genetic counseling, and prenatal diagnosis are effective measures to prevent Hb Bart's hydrops fetalis syndrome. (bvsalud.org)
- Antenatal diagnostic work up done aimed to exclude hydrops fetalis and its numerous aetiologies. (ispub.com)
- Initial diagnoses of non- immune hydrops fetalis possibly due to an infective cause and pulmonary hypoplasia were made. (ispub.com)
- Hydrops fetalis, or hydrops, is a condition in which fluid accumulates in different parts of the fetal body. (columbia.edu)
Ascites4
- Cite this: An Ominous Sign: Fetal Ascites at Mid-gestation - Medscape - Sep 27, 2012. (medscape.com)
- The most common body cavity effusion was pericardial effusion, ascites, and fetal systemic edema. (bvsalud.org)
- This process can lead to fetal anemia, and in severe cases can progress to hydrops (edema), ascites, heart failure, and death. (wikipedia.org)
- The fetal physiological consequences of severe anemia in the fetus can also lead to edema, ascites, hydrops, heart failure, and death. (ashpublications.org)
Fetuses2
- Ultrasonographic findings (see the images below) are often reliably helpful in the diagnosis of the disease causing fetal hydrops, especially in fetuses in whom a chest mass or cardiac disease is present. (medscape.com)
- Fetal survival rates after intrauterine transfusion through the umbilical cord are more than 90% for fetuses that do not have hydrops and about 75% for fetuses that have hydrops. (wikipedia.org)
Fetus3
- During the procedure, medicine may be given to the fetus to temporarily stop fetal movement. (wikipedia.org)
- Possible outcomes include no harm to the fetus, fetal loss, fetal malformation, preterm delivery, fetal growth restriction or postnatal infection. (aafp.org)
- Hemolytic disease of the fetus and newborn (HDFN) is rare condition that occurs when maternal red blood cell (RBC) or blood group antibodies cross the placenta during pregnancy and cause fetal red cell destruction. (ashpublications.org)
Doppler3
- Color Doppler interrogation of the fetal brain showed markedly increased vascularity within the fetal brain at the level of the circle of Willis (Figure 4 ). (hindawi.com)
- [ 6 ] In this case, on the basis of elevated middle cerebral Doppler velocity and evidence of fetal hydrops, severe anemia was suspected. (medscape.com)
- Fetal anemia is monitored throughout pregnancy using Doppler measurement of the middle cerebral artery (MCA) peak systolic velocity (PSV). (wikipedia.org)
Edema2
- In mirror syndrome, maternal hypertension, edema, and often proteinuria are present in association with fetal hydrops. (medscape.com)
- Other anomalies become evident later in the second trimester, as organ systems develop: cardiac malformations, duodenal atresia, hydrops, choroid plexus cysts, nuchal edema, renal pyelectasis, omphalocele, hypoplastic midphalanx of the fifth finger, and short femur and humerus can be used to screen for aneuploidy. (parents-life.com)
Nonimmune1
- If the prenatal patient becomes infected with fifth disease during the first 20 weeks of gestation, the risk of fetal manifestations is about 9 percent and includes nonimmune hydrops and death. (aafp.org)
Prenatal diagnosis2
- Fetal medicine is a complex undertaking that involves a multidisciplinary team for prenatal diagnosis and fetal therapy. (medscape.com)
- However, below we will try to describe the main methods of prenatal diagnosis of fetal used today in most medical institutions of Ukraine. (parents-life.com)
Anomalies1
- [ 9 ] Fetal cardiac anomalies are the most common cause of NIHF, and chromosomal anomalies are the second-most-common cause. (medscape.com)
Echocardiography3
- Fetal echocardiography confirmed a dilated right atrium and ventricle (Figure 1 ). (hindawi.com)
- Fetal echocardiography demonstrating right atrial and ventricular enlargement. (hindawi.com)
- Fetal echocardiography will be recommended to further evaluate fetal heart structure and function. (columbia.edu)
Umbilical3
- At this point, invasive testing via percutaneous umbilical cord blood sampling (PUBS, also called cordocentesis), potentially followed by fetal transfusion is indicated. (wikipedia.org)
- If insertion into an umbilical vessel is not possible, blood may be transfused into the fetal abdomen. (wikipedia.org)
- With cordocentesis, cord blood is taken by entering the umbilical cord after the 20th week of pregnancy and genetic examination is possible. (aliekiz.com)
Ultrasound2
- A 36-year-old gravida 6 para 3 presented at 37 and 5/7 completed gestational weeks with ultrasound findings suggestive of chronic fetal anemia such as right ventricular enlargement, diminished cerebral vascular resistance, and elevated middle cerebral artery end-diastolic velocity. (hindawi.com)
- In Ukraine, non-invasive prenatal testing (NIPT) has been approved for use as a second-line screening test for those identified by conventional screening (based on ultrasound and maternal serum markers) as having an increased chance of fetal Down syndrome (or trisomy 13 or 18). (parents-life.com)
Abnormalities1
- The panel findings, along with gestational age, can suggest a number of fetal abnormalities, depending on the results pattern. (medscape.com)
Anemia6
- One should consider FMH as part of the differential diagnosis for fetal or immediate neonatal anemia. (hindawi.com)
- The degree of fetal anemia can be measured directly by cordocentesis or determined indirectly through middle cerebral artery velocity measurements. (medscape.com)
- It is used in cases of severe fetal anemia, such as when fetal red blood cells are being destroyed by maternal antibodies. (wikipedia.org)
- This non-invasive technique is used as a surrogate measurement for assessing fetal anemia. (wikipedia.org)
- The result confirms the level of fetal anemia and indicates the correct amount of blood to be transfused. (wikipedia.org)
- In cases where severe anemia is suspected as a cause, cordocentesis may be recommended. (columbia.edu)
Amniocentesis1
- However, invasive fetal testing must eventually be performed by means of amniocentesis or cordocentesis. (medscape.com)
Placenta1
- It occurs when maternal antibodies cross the placenta during pregnancy and destroy fetal red blood cells (RBCs). (wikipedia.org)
Characterized by maternal1
- Mirror syndrome is a rare entity characterized by maternal disease that mimics fetal hydrops. (medscape.com)
Gestational2
- A 36-year-old gravida 6 para 3 at 37 and 5/7 completed gestational weeks was referred to our perinatal diagnostic center for fetal right atrial enlargement. (hindawi.com)
- A 42 year old gravida 8 para 9 + 0 rhesus positive mother was referred to the pediatric Surgery unit at Cornwall Regional Hospital at 35 weeks gestational age for non immune hydrops. (ispub.com)
Chromosomal1
- Screening tests screen for various fetal metabolic, chromosomal, and anatomic defects. (medscape.com)
Obstetrician1
- Prenatal care will be managed by a maternal-fetal medicine specialist, an obstetrician with special training and expertise in high-risk pregnancies. (columbia.edu)
Transfusions2
- With the introduction of widespread immunoprophylaxis for red blood cell alloimmunization and the use of in utero transfusions for immune hydrops therapy, IHF represents a minority of cases. (medscape.com)
- Risks of intrauterine transfusions may include uterine infection, fetal infection, preterm labor, excessive bleeding and mixing of fetal and maternal blood, amniotic fluid leakage from the uterus, or (rarely) fetal death. (wikipedia.org)
Maternal circulation2
- Fetomaternal hemorrhage represents a transfer of fetal blood to the maternal circulation. (hindawi.com)
- Fetomaternal hemorrhage (FMH) refers to the passage of fetal blood into the maternal circulation before or during delivery. (hindawi.com)
Neonatal1
- Fetal and neonatal consequences include low birth weight and poor mental and psychomotor performance. (medscape.com)
Hematocrit2
- the fetal hematocrit was 8.8% with a platelet count of 117,000 cells/µL. (medscape.com)
- The fetal blood sample is drawn and immediately analyzed for hematocrit using an automated analyzer in the operating room or hospital hematology laboratory. (wikipedia.org)
Pregnancy2
- The primary risk of maternal chickenpox in early pregnancy is fetal infection, which may result in the congenital varicella syndrome. (aafp.org)
- 20-38% of women with unexplained high MS-AFP (ie, in the absence of fetal abnormality) suffer adverse pregnancy outcomes (premature birth, preeclampsia, 2-4 x IUGR, 10 x perinatal mortality, 10 x placental abruption)! (radiologykey.com)
Biophysical3
- On the other hand, signs of acute fetal decompensation such as deterioration of the fetal heart tracing, diminished biophysical score, decreased cord pH, and increased cord base deficit were noted. (hindawi.com)
- A biophysical profile was performed the following morning and revealed a score of 2/10 with recurrent fetal decelerations. (hindawi.com)
- Fetal monitoring was done using biophysical profiles and daily kick charts. (ispub.com)
Antibodies1
- It is due to maternal blood group antibodies that cause fetal red cell destruction and in some cases, marrow suppression. (ashpublications.org)
Fluid2
- Amniotic fluid was collected before the procedure for fetal karyotype and polymerase chain reaction (PCR) for parvovirus B19. (medscape.com)
- This is caused by fluid accumulation at the back of the fetal neck. (parents-life.com)
Destruction1
- The immune type is caused by destruction of fetal red blood cells by the mother's immune system. (columbia.edu)
Heart1
- The patient was kept overnight for observation due to a nonreactive fetal heart rate tracing. (hindawi.com)
Methods1
- Both methods pose a risk of fetal death. (medscape.com)
Blood cells1
- In addition, the A and B antigens are not well developed on fetal red blood cells. (ashpublications.org)
Risk1
- If the prenatal patient is infected with the varicella-zoster virus, the risk of fetal manifestations is less than 2 percent. (aafp.org)