• In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. (unl.edu)
  • Human esterase-D, also a type-B carboxylesterase, does not seem to be evolutionary related. (expasy.org)
  • Carboxylesterase 1 is a member of a large family of carboxylesterases that are responsible for the hydrolysis of ester and amide bonds (1, 2). (rndsystems.com)
  • Carboxylic ester hydrolase , 9homo-a0a0d7ay28 Cylindrobasidium torrendii FP15055 ss-10. (inra.fr)
  • Carboxylic ester hydrolase , 9homo-a0a0d7b4n4 Cylindrobasidium torrendii FP15055 ss-10. (inra.fr)
  • Carboxylic ester hydrolase , 9homo-a0a0d7b624 Cylindrobasidium torrendii FP15055 ss-10. (inra.fr)
  • Carboxylic ester hydrolase , 9homo-a0a0d7biw2 Cylindrobasidium torrendii FP15055 ss-10. (inra.fr)
  • Carboxylic ester hydrolase , 9euro-a0a0f8v754 Aspergillus ochraceoroseus. (inrae.fr)
  • 3.1.1.1) are serine hydrolases known to metabolize xenobiotics containing ester amide and thioester bonds (see [13] for review). (ecologicalsgardens.com)
  • Orthologous to human NOTUM (notum, palmitoleoyl-protein carboxylesterase). (zfin.org)
  • Saboori and Newcombe [19] previously showed that a carboxylesterase protein which was purified from human monocytes could be inhibited by oxon treatment. (ecologicalsgardens.com)
  • Red cell acylpeptide hydrolase (APH) was shown to be an improved biomarker for exposure to the oxon forms of chlorpyrifos and diazoxon with the added advantages of a much longer half-life of the OP adducted protein compared with butyrylcholinesterase (BChE) (33d vs. 11d) and a significantly increased sensitivity of OP adduct determination. (nih.gov)
  • Ten genes were transcriptionally induced exclusively by the BP178 therapy, and seven of them is usually mapped and identified as pathogenesis-related protein1, glycosidase, a member of ABC transporter loved ones, ser/thr protein kinase, cold shock protein (chaperone), pre-mRNAsplicing issue CLF1, and CXE carboxylesterase. (atminhibitor.com)
  • Duck acyl-[acyl-carrier protein] hydrolase, medium chain (EC 3.1.2.14 ), an enzyme that may be associated with peroxisome proliferation and may play a role in the production of 3-hydroxy fatty acid diester pheromones. (expasy.org)
  • its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. (unl.edu)
  • Carboxylesterases among other serine hydrolases are inhibited by covalent reaction of the active-site serine residue with organophosphate compounds (oxons) [13]. (ecologicalsgardens.com)
  • Moreover we show that treatment of cholesterol-loaded THP-1 macrophages with a specific reversible inhibitor of CES1 (benzil) GPSA or a bioactive metabolite of an OP insecticide (paraoxon) that broadly targets multiple serine hydrolases including CES1 causes significant retention of cholesteryl esters in cultured macrophages under conditions which promote lipoprotein-dependent cholesterol efflux. (ecologicalsgardens.com)
  • In this study, we have used a murine liver microsomal system to investigate the relative contributions of P450 and carboxylesterase isozymes to hepatic metabolism of EC. (aspetjournals.org)
  • however, reaction with PAX and not PMSF or EC resulted in loss of immunoreactivity for hydrolase B. These data correlated with levels of covalent binding of [ ethyl - 14 C]EC to liver microsomes, which were significantly elevated in incubations conducted with PAX or PMSF. (aspetjournals.org)
  • These results are consistent with the premise that EC is metabolized by CYP2E1 and hydrolase A in liver microsomes of mice. (aspetjournals.org)
  • 2 The antibodies for the carboxylesterases were raised against rat liver microsomal hydrolase A and hydrolase B. For ease of description, the murine liver microsomal proteins recognized by these antibodies are designated with the same nomenclature. (aspetjournals.org)
  • The first ORF showed high homology with xylanases belonging to family 8 of the glycoside hydrolases and this gene was designated xylA . (megazyme.com)
  • The second ORF was the axhD3 gene belonging to glycoside hydrolase family 43. (megazyme.com)
  • Phenmedipham hydrolase (phenylcarbamate hydrolase), an Arthrobacter oxidans plasmid-encoded enzyme (gene pcd) that degrades the phenylcarbamate herbicides phenmedipham and desmedipham by hydrolyzing their central carbamate linkages. (expasy.org)
  • Biochemistry bioassays confirmed the involvement of monooxygenase enzyme, carboxylesterase, superoxide dismutase and peroxidase in multi-insecticide resistance mechanism. (preprints.org)
  • An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. (ouhsc.edu)
  • Except the hydrolase, each of the other genes code for proteins straight involved in plant-defense responses. (atminhibitor.com)
  • Alpha/beta-hydrolase , 9homo-a0a0d7b1w8 Cylindrobasidium torrendii FP15055 ss-10. (inra.fr)
  • Alpha/beta-hydrolase , 9homo-a0a0d7bdn7 Cylindrobasidium torrendii FP15055 ss-10. (inra.fr)
  • Predicted to enable palmitoleyl hydrolase activity. (zfin.org)
  • Carboxylic ester hydrolase , lyghe-a0a0k8spt0 Lygus hesperus (Western plant bug) Uncharacterized protein , lyghe-a0a0k8sth4 Lygus hesperus (Western plant bug) Uncharacterized protein , lyghe-a0a146kuv1 Lygus hesperus (Western plant bug). (inra.fr)
  • In this study, a protein annotated as a carbamate C-N hydrolase was identified in the methomyl-degrading strain Aminobacter aminovorans MDW-2, and the encoding gene was termed ameH. (usda.gov)
  • Ten genes were transcriptionally induced exclusively by the BP178 therapy, and seven of them is usually mapped and identified as pathogenesis-related protein1, glycosidase, a member of ABC transporter loved ones, ser/thr protein kinase, cold shock protein (chaperone), pre-mRNAsplicing issue CLF1, and CXE carboxylesterase. (atminhibitor.com)
  • 16. Synergistic role of specificity proteins and upstream stimulatory factor 1 in transactivation of the mouse carboxylesterase 2/microsomal acylcarnitine hydrolase gene promoter. (nih.gov)
  • Belongs to the AB hydrolase superfamily. (expasy.org)
  • Putative serine hydrolase , lyghe-a0a0a9zhh3 Lygus hesperus (Western plant bug). (inra.fr)
  • During the development of the seed coat, the expression of the synthesis-related gene GGTs and the hydrolase gene TAs was continuously decreased, resulting in the decrease of tannin content in the dry sample of the seed coat of Chinese hickory. (figshare.com)
  • An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. (wakehealth.edu)
  • Thermobifida fusca cutinase ( TfC ) is a carboxylesterase (CE) that degrades the environmental pollutant, polyethylene terephthalate (PET). (authorea.com)
  • FC 3.16), a glycoprotein involved in signaling mechanisms (FC 5.38), acetyltransferase (FC four.26), and hydrolase (FC three.39). (atminhibitor.com)
  • Except the hydrolase, each of the other genes code for proteins straight involved in plant-defense responses. (atminhibitor.com)
  • The phylogenetic and sequence analysis showed that TA genes and neighboring clade genes (TA-like genes) had similar sequences compared with other carboxylesterase genes, which may be the origin of TA genes produced by tandem repeat. (figshare.com)
  • AChE is a hydrolase that hydrolyzes choline esters. (wikipedia.org)
  • The I 50 s values of dichlorvos to carboxylesterase for L. bostrychophila and L. entomophila were 1.43 and 3.28 µM, respectively, and to AChE were 324 and 612 nM, respectively. (bioone.org)
  • Szafran, Brittany Nichole, "The role of the endocannabinoid system in immune homeostasis with an emphasis on the immune effects of carboxylesterase inhibition by chlorpyrifos in murine lung tissue" (2021). (msstate.edu)
  • Carboxylesterase 1 is a member of a large family of carboxylesterases that are responsible for the hydrolysis of ester and amide bonds (1, 2). (rndsystems.com)
  • ZHANG L,GAO X,LIANG P. Beta -cypermethrin resistance associated with high carboxylesterase activities in a strain of house fly, Musca domestica (Diptera:Muscidae)[J]. Pestic Biochem Phys, 2007,89:65-72. (nyxxb.cn)
  • First, a negative feedback mechanism between inflammation and the eCB system was examined by identifying serine hydrolases inhibited by lipopolysaccharide (LPS) stimulation in mice. (msstate.edu)
  • Human carboxylesterase 2 (CES2) has triacylglycerol hydrolase (TGH) activities and plays an important role in lipolysis. (omeka.net)