LipaseEsteraseEsterProteinEnzymesSerine hydrolasesPutativeLiverGlycosidePhenmediphamCES1EnzymeProteinsAlphaActivityEstersProteinAcylcarnitine hydrolaseSuperfamilyPutativeGeneEnzymeTriacylglycerol lipaseBioHCutinaseAcetyltransferaseGenesAChEInhibitionAcetylcholinesteraseFamilyStrainMechanismMiceHUMAN
Lipase1
- Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. (unl.edu)
Esterase2
- In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. (unl.edu)
- Human esterase-D, also a type-B carboxylesterase, does not seem to be evolutionary related. (expasy.org)
Ester7
- Carboxylesterase 1 is a member of a large family of carboxylesterases that are responsible for the hydrolysis of ester and amide bonds (1, 2). (rndsystems.com)
- Carboxylic ester hydrolase , 9homo-a0a0d7ay28 Cylindrobasidium torrendii FP15055 ss-10. (inra.fr)
- Carboxylic ester hydrolase , 9homo-a0a0d7b4n4 Cylindrobasidium torrendii FP15055 ss-10. (inra.fr)
- Carboxylic ester hydrolase , 9homo-a0a0d7b624 Cylindrobasidium torrendii FP15055 ss-10. (inra.fr)
- Carboxylic ester hydrolase , 9homo-a0a0d7biw2 Cylindrobasidium torrendii FP15055 ss-10. (inra.fr)
- Carboxylic ester hydrolase , 9euro-a0a0f8v754 Aspergillus ochraceoroseus. (inrae.fr)
- 3.1.1.1) are serine hydrolases known to metabolize xenobiotics containing ester amide and thioester bonds (see [13] for review). (ecologicalsgardens.com)
Protein5
- Orthologous to human NOTUM (notum, palmitoleoyl-protein carboxylesterase). (zfin.org)
- Saboori and Newcombe [19] previously showed that a carboxylesterase protein which was purified from human monocytes could be inhibited by oxon treatment. (ecologicalsgardens.com)
- Red cell acylpeptide hydrolase (APH) was shown to be an improved biomarker for exposure to the oxon forms of chlorpyrifos and diazoxon with the added advantages of a much longer half-life of the OP adducted protein compared with butyrylcholinesterase (BChE) (33d vs. 11d) and a significantly increased sensitivity of OP adduct determination. (nih.gov)
- Ten genes were transcriptionally induced exclusively by the BP178 therapy, and seven of them is usually mapped and identified as pathogenesis-related protein1, glycosidase, a member of ABC transporter loved ones, ser/thr protein kinase, cold shock protein (chaperone), pre-mRNAsplicing issue CLF1, and CXE carboxylesterase. (atminhibitor.com)
- Duck acyl-[acyl-carrier protein] hydrolase, medium chain (EC 3.1.2.14 ), an enzyme that may be associated with peroxisome proliferation and may play a role in the production of 3-hydroxy fatty acid diester pheromones. (expasy.org)
Enzymes3
- Cytochrome P450 and carboxylesterase enzymes have been implicated in the metabolism of the carcinogen ethyl carbamate (EC). (aspetjournals.org)
- N -Nitrosodimethylamine (NDMA) demethylation and p -nitrophenyl acetate (PNA) hydrolysis were used as catalytic markers of CYP2E1 and carboxylesterase enzymes, respectively. (aspetjournals.org)
- It belongs to the carboxylesterase family of enzymes. (wikipedia.org)
Serine hydrolases3
- its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. (unl.edu)
- Carboxylesterases among other serine hydrolases are inhibited by covalent reaction of the active-site serine residue with organophosphate compounds (oxons) [13]. (ecologicalsgardens.com)
- Moreover we show that treatment of cholesterol-loaded THP-1 macrophages with a specific reversible inhibitor of CES1 (benzil) GPSA or a bioactive metabolite of an OP insecticide (paraoxon) that broadly targets multiple serine hydrolases including CES1 causes significant retention of cholesteryl esters in cultured macrophages under conditions which promote lipoprotein-dependent cholesterol efflux. (ecologicalsgardens.com)
Putative1
- The third (partial) ORF coded for a putative carboxylesterase. (megazyme.com)
Liver4
- In this study, we have used a murine liver microsomal system to investigate the relative contributions of P450 and carboxylesterase isozymes to hepatic metabolism of EC. (aspetjournals.org)
- however, reaction with PAX and not PMSF or EC resulted in loss of immunoreactivity for hydrolase B. These data correlated with levels of covalent binding of [ ethyl - 14 C]EC to liver microsomes, which were significantly elevated in incubations conducted with PAX or PMSF. (aspetjournals.org)
- These results are consistent with the premise that EC is metabolized by CYP2E1 and hydrolase A in liver microsomes of mice. (aspetjournals.org)
- 2 The antibodies for the carboxylesterases were raised against rat liver microsomal hydrolase A and hydrolase B. For ease of description, the murine liver microsomal proteins recognized by these antibodies are designated with the same nomenclature. (aspetjournals.org)
Glycoside2
- The first ORF showed high homology with xylanases belonging to family 8 of the glycoside hydrolases and this gene was designated xylA . (megazyme.com)
- The second ORF was the axhD3 gene belonging to glycoside hydrolase family 43. (megazyme.com)
Phenmedipham1
- Phenmedipham hydrolase (phenylcarbamate hydrolase), an Arthrobacter oxidans plasmid-encoded enzyme (gene pcd) that degrades the phenylcarbamate herbicides phenmedipham and desmedipham by hydrolyzing their central carbamate linkages. (expasy.org)
CES11
- CES1 and carboxylesterase 2 (CES2) are the two major human carboxylesterase isoforms and share 48% sequence homology. (ecologicalsgardens.com)
Enzyme2
- Biochemistry bioassays confirmed the involvement of monooxygenase enzyme, carboxylesterase, superoxide dismutase and peroxidase in multi-insecticide resistance mechanism. (preprints.org)
- An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. (ouhsc.edu)
Proteins1
- Except the hydrolase, each of the other genes code for proteins straight involved in plant-defense responses. (atminhibitor.com)
Alpha2
Activity1
- Predicted to enable palmitoleyl hydrolase activity. (zfin.org)
Esters1
- AChE is a hydrolase that hydrolyzes choline esters. (wikipedia.org)
Protein3
- Carboxylic ester hydrolase , lyghe-a0a0k8spt0 Lygus hesperus (Western plant bug) Uncharacterized protein , lyghe-a0a0k8sth4 Lygus hesperus (Western plant bug) Uncharacterized protein , lyghe-a0a146kuv1 Lygus hesperus (Western plant bug). (inra.fr)
- In this study, a protein annotated as a carbamate C-N hydrolase was identified in the methomyl-degrading strain Aminobacter aminovorans MDW-2, and the encoding gene was termed ameH. (usda.gov)
- Ten genes were transcriptionally induced exclusively by the BP178 therapy, and seven of them is usually mapped and identified as pathogenesis-related protein1, glycosidase, a member of ABC transporter loved ones, ser/thr protein kinase, cold shock protein (chaperone), pre-mRNAsplicing issue CLF1, and CXE carboxylesterase. (atminhibitor.com)
Acylcarnitine hydrolase1
- 16. Synergistic role of specificity proteins and upstream stimulatory factor 1 in transactivation of the mouse carboxylesterase 2/microsomal acylcarnitine hydrolase gene promoter. (nih.gov)
Superfamily1
- Belongs to the AB hydrolase superfamily. (expasy.org)
Putative1
- Putative serine hydrolase , lyghe-a0a0a9zhh3 Lygus hesperus (Western plant bug). (inra.fr)
Gene1
- During the development of the seed coat, the expression of the synthesis-related gene GGTs and the hydrolase gene TAs was continuously decreased, resulting in the decrease of tannin content in the dry sample of the seed coat of Chinese hickory. (figshare.com)
Enzyme1
- An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. (wakehealth.edu)
Triacylglycerol lipase2
- Now known to be catalysed by EC 3.1.1.1 , carboxylesterase and EC 3.1.1.3 , triacylglycerol lipase. (genome.jp)
- Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. (unl.edu)
BioH1
- Carboxylesterase BioH family. (expasy.org)
Cutinase1
- Thermobifida fusca cutinase ( TfC ) is a carboxylesterase (CE) that degrades the environmental pollutant, polyethylene terephthalate (PET). (authorea.com)
Acetyltransferase1
- FC 3.16), a glycoprotein involved in signaling mechanisms (FC 5.38), acetyltransferase (FC four.26), and hydrolase (FC three.39). (atminhibitor.com)
Genes2
- Except the hydrolase, each of the other genes code for proteins straight involved in plant-defense responses. (atminhibitor.com)
- The phylogenetic and sequence analysis showed that TA genes and neighboring clade genes (TA-like genes) had similar sequences compared with other carboxylesterase genes, which may be the origin of TA genes produced by tandem repeat. (figshare.com)
AChE2
- AChE is a hydrolase that hydrolyzes choline esters. (wikipedia.org)
- The I 50 s values of dichlorvos to carboxylesterase for L. bostrychophila and L. entomophila were 1.43 and 3.28 µM, respectively, and to AChE were 324 and 612 nM, respectively. (bioone.org)
Inhibition1
- Szafran, Brittany Nichole, "The role of the endocannabinoid system in immune homeostasis with an emphasis on the immune effects of carboxylesterase inhibition by chlorpyrifos in murine lung tissue" (2021). (msstate.edu)
Acetylcholinesterase1
- To investigate a separate mechanism by which serine hydrolases and eCBs may regulate immune responses, mice were treated with chlorpyrifos (CPF), a pesticide known to inhibit serine hydrolases, at doses that do not inhibit acetylcholinesterase in the nervous system. (msstate.edu)
Family1
- Carboxylesterase 1 is a member of a large family of carboxylesterases that are responsible for the hydrolysis of ester and amide bonds (1, 2). (rndsystems.com)
Strain1
- ZHANG L,GAO X,LIANG P. Beta -cypermethrin resistance associated with high carboxylesterase activities in a strain of house fly, Musca domestica (Diptera:Muscidae)[J]. Pestic Biochem Phys, 2007,89:65-72. (nyxxb.cn)
Mechanism1
- First, a negative feedback mechanism between inflammation and the eCB system was examined by identifying serine hydrolases inhibited by lipopolysaccharide (LPS) stimulation in mice. (msstate.edu)
Mice1
- Hepatocyte-specific expression of human carboxylesterase 2 attenuates nonalcoholic steatohepatitis in mice. (omeka.net)
HUMAN1
- Human carboxylesterase 2 (CES2) has triacylglycerol hydrolase (TGH) activities and plays an important role in lipolysis. (omeka.net)